• 제목/요약/키워드: residue study

검색결과 1,374건 처리시간 0.025초

농약 및 동물용의약품으로 사용되는 약제의 잔류허용기준 설정 개선 - 축산물 중 cypermethrin의 잔류 사례 (Harmonization of MRL Setting for Compounds Used Both as Pesticides and as Veterinary Drugs with Regulatory Aspects - Cypermethrin in Food of Animal Origin)

  • 권진욱
    • 한국환경농학회지
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    • 제30권1호
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    • pp.89-97
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    • 2011
  • 축산물 중 cypermethrin 잔류를 예로 농약 및 농물용의 약품으로 사용되는 약제와 이성질체를 포함한 약제에 대한 잔류허용기준 설정의 문제점과 개선사항을 실험과 문헌을 통해 검토하였다. 과학적이고 합리적인 잔류허용기준설정을 위해서는 분석 대상 시료 및 적용부위의 명확성과 합의된 정의의 도출 그리고, 분석 대상화합물의 명확한 지정이 있어야 한다. 그리고 이를 바탕으로 규제 검사, 연구목적의 모니터링, 관련 분석법 개발 등이 보다 깊은 연관성을 가질수 있도록 관련 전문가들의 관심과 합의점 도출은 매우 중요하다.

Bioconcentration of Pirimiphos-methyl in Killifish (Oryzias latipes)

  • Seo, Jong-Su;Chang, Hee-Ra;Hamer, Mick;Kim, Kyun
    • 한국환경농학회지
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    • 제28권4호
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    • pp.453-461
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    • 2009
  • Killifish (Oryzias latipes) were exposed to an organophosphate pesticide, pirimiphos-methyl, in a flow-through system to determine the bioconcentration factor (BCF) following GLP (Good Laboratory Practice). This study was conducted at two different concentrations (1 and $10\;{\mu}$g/L) of $^{14}C$-labeled pirimiphos-methyl for 28 days uptake and 14 days depuration according to the OECD 305 test guideline. The $BCF_{ss}$ for total radioactive residues in whole fish were 1,251 and 1,277 for low and high concentrations, respectively. The $BCF_k$ based on the uptake and depuration rate constants were 1,200 for both low and high concentrations. During the depuration phase, the accumulated test substance was rapidly depurated from fish. Greater than 95% of the residue at steady-state was depurated after 2 days. Although the measured BCF values were high, pirimiphos-methyl could be evaluated as a low risk from bioaccumulation by aquatic organisms due to the short depuration period and low amount of bound residue (1.5%). We suggest that in evaluating bioaccumulation, not only the BCF should be considered, but also depuration time and bound residue in aquatic organisms give an indication of the potential environmental risks.

$CHF_3$/$C_2$$F_6$ 반응성이온 건식식각에 의한 실리콘 표면의 오염 및 제거에 관한 연구 (A Study on the Silicon surface and near-surface contamination by $CHF_3$/$C_2$$F_6$ RIE and its removal with thermal treatment and $O_2$ plasma exposure)

  • 권광호;박형호;이수민;곽병화;김보우;권오준;성영권
    • 전자공학회논문지A
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    • 제30A권1호
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    • pp.31-43
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    • 1993
  • Thermal behavior and $O_{2}$ plasma effects on residue and penetrated impurities formed by reactive ion etching (RIE) in CHF$_{3}$/C$_{2}$F$_{6}$ have been investigated using X-ray photoelectron spectroscopy (XPS) and secondary ion mass spectrometry (SIMS) techniques. Decomposition of polymer residue film begins between 200-300.deg. C, and above 400.deg. C carbon compound as graphite mainly forms by in-situ resistive heating. It reveals that thermal decomposition of residue can be completed by rapid thermal anneal above 800.deg. C under nitrogen atmosphere and out-diffusion of penetrated impurities is observed. The residue layer has been removed with $O_{2}$ plasma exposure of etched silicon and its chemical bonding states have been changed into F-O, C-O etc.. And $O_{2}$ plasma exposure results in the decrease of penetrated impurities.

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고속 그래픽 처리를 위한 잉여수계 승산기 설계에 관한 연구 (A Study on the design of RNS Multiplier to speed up the Graphic Process)

  • 김용성;조원경
    • 전자공학회논문지B
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    • 제33B권1호
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    • pp.25-37
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    • 1996
  • 실시간 컴퓨터 그래픽 처리를 위하여는 고속 연산(승산 및 가산)회로가 필요하다. 잉여수 체계(RNS:Residue Number System)는 병렬성과 고속성을 갖는 정수연산체계이고, 또한 순환군(cyclic group)은 가산과 승산이 동형인 잉여수 연산을 수행하므로 고속의 승산기와 가산기의 설계가 가능하다. 그러므로, 본 논문에서는 DRNS(Double Residue Number System)를 제안하고, 순환부호(circula- tive code)를 이용한 고속의 잉여수 승산기를 설계하여, 이를 그래픽 프로세서의 연산기로 사용하고자 한다. 설계된 승산기는 TTL소자 74s09, 74s32를 사용한 경우 87MHz속도의 연산이 가능하다.

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식혜의 이소말토올리고당에 관한 연구(II) -효소적 분석- (A Study on Sugars in Korean Sweet Rice Drink "Sikhye"(II) -Enzymatic Analysis of Isomaltooligosaccharides and Rice Residue-)

  • 안용근
    • 한국식품영양학회지
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    • 제10권1호
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    • pp.87-91
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    • 1997
  • 식혜에 함유된 이소말토올리고당과 밥알에 30unit/ml의 $\alpha$-아밀라아제, 글루코아밀라아제, $\alpha$-글루코시다아제, $\beta$-아밀라아제를 가하여 작용시킨 결과 글루코아밀라아제 외에는 일부밖에 가수분해하지 못하였다. 그리고, 인체의 효소인 $\alpha$-아밀라아제와 $\alpha$-글루코시다아제를 함께 작용시켜도 25% 이상 가수분해하지 못하므로 비피두스균의 활성인자로 작용할 것으로 보인다. 밥알은 물에 녹지 않기 때문에 식이섬유로도 작용할 것으로 보인다.

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규석 분말도에 따른 ALC의 물리적 특성 변화 (Physical Properties of ALC with Various Fineness of Quartzite)

  • 추용식;정의종;송훈;이종규;김영곤;강대구
    • 한국세라믹학회지
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    • 제47권5호
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    • pp.407-411
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    • 2010
  • ALC was fabricated using cement, lime and quartzite by hydrothermal reaction. ALC has low strength and brittleness on account of inner pores. The studies for resolving these problems were driven by many researchers. Among these researches, the controls of quartzite fineness have been studied for unsuitable properties of ALC. This study experimented with variation of 90 ${\mu}m$ residue for obtain good physical properties. It was found that 90 ${\mu}m$ residue influenced on physical properties of ALC. The lower amount of 90 ${\mu}m$ residue, the higher compressive and bending strength. But the continuing decrease of 90 ${\mu}m$ residue did not cause the increase of strength. In order to application of these results in process, the states of process and hydrothermal products will be considered.

망간단괴-Cd 상호작용에 대한 등온흡착식 적용 (Application of Adsorption Isotherms for Manganese Nodule-Cadmium Interaction)

  • 전영신;김진화;김동수
    • 자원리싸이클링
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    • 제8권1호
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    • pp.37-43
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    • 1999
  • 본 연구는 망간단괴와 그로부터 유가금속을 침출한 잔사를 카드뮴 폐수의 흡착제로 이용하는 기초실험으로 초기 카드뮴 농도에 따른 흡착성을 살펴보았다. 또한 이를 Freundlich, Langmuir, Temkin 등온흡착식에 적용하여 각 흡착계를 설명하였다. 카드뮴 이온의 초기농도가 증가함에 따라 흡착량은 증가하였으나 흡착성은 점차로 감소하는 경향을 보였다. 이를 Freundlich, Langmuir 식에 적용한 결과, 선형성을 나타내었다. 그리고 Freundlich 식에서 흡착제의 흡착능력을 평가하는 k값은 망간단괴가 11.72로 제일 컸다. 망간단괴의 경우는 Langmuirtlr의 단분자층을 형성하여 흡착되는 흡착질의 최대흡착량인 $X_m$값또한 0.16으로 침출잔사, 잔사-생단괴 혼합, 활성탄에 비해 큼을 알 수 있었다.

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A Lattice Model Study of Native Contact Restraints in Protein Folding

  • 오원석;신재민
    • Bulletin of the Korean Chemical Society
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    • 제17권9호
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    • pp.808-813
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    • 1996
  • To explore protein folding mechanism, we simulated a folding pathway in a simplified 3×3×3 cubic lattice. In the lattice folding Monte Carlo simulations, each of the 28 possible native packing pairs that exist in the native conformation was used as a conformational restraint. The native packing restraints in the lattice model could be considered as a disulfide linkage restraint in a real protein. The results suggest that proteins denatured with a small disulfide loop can, but not always, fold faster than proteins without any disulfide linkage and than proteins with a larger disulfide loop. The results also suggest that there is a rough correlation between loop size of the native packing restraint and folding time. That is, the order of native residue-residue packing interaction in protein folding is likely dependent on the residue-residue distance in primary sequence. The strength of monomer-monomer pairwise interaction is not important in the determination of the packing order in lattice folding. From the folding simulations of five strong folding lattice sequences, it was also found that the context encoded in the primary sequence, which we do not yet clearly understand, plays more crucial role in the determination of detailed folding kinetics. Our restrained lattice model approach would provide a useful strategy to the future protein folding experiments by suggesting a protein engineering for the fast or slow folding research.

Effect of Flutriafol Exposure on Residue Characteristics in Pig Muscle and Fat Tissue

  • Jeong, Jin Young;Kim, Byeonghyeon;Ji, Sang Yun;Baek, Youl Chang;Kim, Minji;Park, Seol Hwa;Jung, Hyunjung
    • 한국축산식품학회지
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    • 제42권1호
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    • pp.186-196
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    • 2022
  • This study investigated the effect of exposure to flutriafol based on residues in pigs. Pigs were exposed to different concentrations (0.313, 0.625, 3.125, 6.25, and 12.5 mg/kg bw/d, n=20) for 4 wk in different treatment groups. Serum biochemical analysis, residue levels, and histological analysis were conducted using the VetTest chemistry analyzer, liquid chromatography mass spectrometry, and Masson's trichrome staining, respectively. The body weight (initial and final) was not significantly different between groups. Parameters such as creatinine, blood urea nitrogen, alanine aminotransferase, and lipase levels were significantly different as compared to the control group. Flutriafol increased the residue limits in individual tissue of the pigs in a dose dependent manner. Flutriafol exposures indicated the presence of fibrosis, as confirmed from Masson's trichrome staining. These results suggest that flutriafol affects the morphology and serum levels in pigs. The dietary flutriafol levels can provide a basis for maximum residue limits and food safety for pork and related products.

Method of Ga removal from a specimen on a microelectromechanical system-based chip for in-situ transmission electron microscopy

  • Yena Kwon;Byeong-Seon An;Yeon-Ju Shin;Cheol-Woong Yang
    • Applied Microscopy
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    • 제50권
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    • pp.22.1-22.6
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    • 2020
  • In-situ transmission electron microscopy (TEM) holders that employ a chip-type specimen stage have been widely utilized in recent years. The specimen on the microelectromechanical system (MEMS)-based chip is commonly prepared by focused ion beam (FIB) milling and ex-situ lift-out (EXLO). However, the FIB-milled thin-foil specimens are inevitably contaminated with Ga+ ions. When these specimens are heated for real time observation, the Ga+ ions influence the reaction or aggregate in the protection layer. An effective method of removing the Ga residue by Ar+ ion milling within FIB system was explored in this study. However, the Ga residue remained in the thin-foil specimen that was extracted by EXLO from the trench after the conduct of Ar+ ion milling. To address this drawback, the thin-foil specimen was attached to an FIB lift-out grid, subjected to Ar+ ion milling, and subsequently transferred to an MEMS-based chip by EXLO. The removal of the Ga residue was confirmed by energy dispersive spectroscopy.