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http://dx.doi.org/10.5851/kosfa.2021.e61

Effect of Flutriafol Exposure on Residue Characteristics in Pig Muscle and Fat Tissue  

Jeong, Jin Young (Animal Nutrition & Physiology Division, National Institute of Animal Science, Rural Development Administration)
Kim, Byeonghyeon (Animal Nutrition & Physiology Division, National Institute of Animal Science, Rural Development Administration)
Ji, Sang Yun (Animal Nutrition & Physiology Division, National Institute of Animal Science, Rural Development Administration)
Baek, Youl Chang (Animal Nutrition & Physiology Division, National Institute of Animal Science, Rural Development Administration)
Kim, Minji (Animal Nutrition & Physiology Division, National Institute of Animal Science, Rural Development Administration)
Park, Seol Hwa (Animal Nutrition & Physiology Division, National Institute of Animal Science, Rural Development Administration)
Jung, Hyunjung (Animal Nutrition & Physiology Division, National Institute of Animal Science, Rural Development Administration)
Publication Information
Food Science of Animal Resources / v.42, no.1, 2022 , pp. 186-196 More about this Journal
Abstract
This study investigated the effect of exposure to flutriafol based on residues in pigs. Pigs were exposed to different concentrations (0.313, 0.625, 3.125, 6.25, and 12.5 mg/kg bw/d, n=20) for 4 wk in different treatment groups. Serum biochemical analysis, residue levels, and histological analysis were conducted using the VetTest chemistry analyzer, liquid chromatography mass spectrometry, and Masson's trichrome staining, respectively. The body weight (initial and final) was not significantly different between groups. Parameters such as creatinine, blood urea nitrogen, alanine aminotransferase, and lipase levels were significantly different as compared to the control group. Flutriafol increased the residue limits in individual tissue of the pigs in a dose dependent manner. Flutriafol exposures indicated the presence of fibrosis, as confirmed from Masson's trichrome staining. These results suggest that flutriafol affects the morphology and serum levels in pigs. The dietary flutriafol levels can provide a basis for maximum residue limits and food safety for pork and related products.
Keywords
pig; flutriafol; fibrosis;
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