• Information Systems Review
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• v.25 no.4
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• pp.131-159
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• 2023

Recently, amidst the backdrop of the COVID-19 pandemic shifting towards an endemic phase, there has been a rise in discussions and debates about the future of the metaverse. Simultaneously, major metaverse platforms like Roblox have been launching services integrated with generative AI, and Apple's mixed reality hardware, Vision Pro, has been announced, creating new expectations for the metaverse. In this situation where the outlook for the metaverse is divided, it is crucial to diagnose the metaverse from an ecosystem perspective, examine its key ecological features, driving forces for development, and future possibilities for advancement. This study utilized Wang's (2021) Information Ecology Theory (IET) framework, which is representative of ecosystem research in the field of Information Systems (IS), to derive the Metaverse Industrial Ecosystem (MIE). The analysis revealed that the MIE consists of four main domains: Tech Landscape, Category Ecosystem, Metaverse Platform, and Product/Service Ecosystem. It was found that the MIE exhibits characteristics such as digital connectivity, the integration of real and virtual worlds, value creation capabilities, and value sharing (Web 3.0). Furthermore, the interactions among the domains within the MIE and the four characteristics of the ecosystem were identified as driving forces for the development of the MIE at an ecosystem level. Additionally, the development of the MIE at an ecosystem level was categorized into three distinct stages: Narrow Ecosystem, Expanded Ecosystem, and Everywhere Ecosystem. It is anticipated that future advancements in related technologies and industries, such as robotics, AI, and 6G, will promote the transition from the current Expanded Ecosystem level of the MIE to an Everywhere Ecosystem level, where the connection between the real and virtual worlds is pervasive. This study provides several implications. Firstly, it offers a foundational theory and analytical framework for ecosystem research, addressing a gap in previous metaverse studies. It also presents various research topics within the metaverse domain. Additionally, it establishes an academic foundation that integrates concept definition research and impact studies, which are key areas in metaverse research. Lastly, referring to the developmental stages and conditions proposed in this study, businesses and governments can explore future metaverse markets and related technologies. They can also consider diverse metaverse business strategies. These implications are expected to guide the exploration of the emerging metaverse market and facilitate the evaluation of various metaverse business strategies.

• Clinical and Experimental Pediatrics
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• v.48 no.3
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• pp.315-320
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• 2005

Objective : Toll like receptor(TLR) is known to be involved in innate immunity. Many microbial antigens stimulate TLR, and as a result of intracellular signal transduction, they activate nuclear factor-kB which produces diverse inflammtory cytokines. Until now, many research topics in Kawasaki disease focused on cytokine increasement. In this study, we aim to reveal TLR increasement which might be associated with initiation of inflammatory response. Methods : We obtained the peripheral blood of ten patients who were diagnosed with Kawasaki disease in Yonsei University College of Medicine from March 2003 to August 2003, as well as those of a febrile control group and the same number of a normal control group. Flow cytometry was done in all samples for quantification of TLR-2 expression in CD14 positive monocyte. And we also extracted total RNA of periphral monocyte and quantificated expression of TLR-2 mRNA by RT-PCR. Results : The expression of TLR-2 in Kawasaki disease increased significantly compared with the normal control group but not when compared with the febrile control group. And the expression decreased slightly in the subacute phase of Kawasaki disease compared with the acute phase, but this was statistically insignificant. mRNA expression of TLR-2 in peripheral blood monocyte also increased in the acute phase of Kawasaki disease. Conclusion : Expression of TLR-2 in Kawasaki disease increased when compared with the normal control group, which means that innate immunity is associated with the pathogenesis of Kawasaki disease.

• Journal of the Korean Geographical Society
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• v.47 no.4
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• pp.606-624
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• 2012

The main objective of this paper is to provide an adequate and comprehensive review of what has been done in South Korea in the field of geospatial analysis and modeling. This review focuses on spatial data analysis and spatial statistics, spatial optimization, and geosimulation among various aspects of the field. It is recognized that geospatial analysis and modeling in South Korea got through the initial stage during the 1990s when computer and analytical cartography and GIS were introduced, moved to the growth stage during the first decade of the $21^{st}$ century when there was a surge of relevant researches, and now is heading for its maturity stage. In spatial data analysis and spatial statistics, various topics have been addressed for spatial point pattern data, areal data, geostatistical data, and spatial interaction data. In spatial optimization, modeling and applications related to facility location problems, districting problems, and routing problems have been mostly researched. Finally, in geosimulation, while most of research has focused on cellular automata, studies on agent-based model and simulation are in beginning stage. Among all these works, some have fostered methodological advances beyond simple applications of the standard techniques.

• Quality Improvement in Health Care
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• v.4 no.1
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• pp.82-103
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• 1997

Background : With increased concerns about variation among physician's practice pattern and their impact on the quality of care, clinical practice guidelines have been developed by many different organizations, with differing aims and incentives. From the same point of view, there is growing interest in the development of clinical practice guidelines in Korea, but with only a few examples. As a result, there is not much exploration on the incentive and barrier to develop guidelines as well as description on the development process. The purposes of this study are to describe the process of the four different clinical practice guidelines in a hospital setting, and to identify incentives and barriers in the development of guidelines. Methods : For this research, a clinical practice guideline development committee and four clinical practice guideline development teams were organized in a university hospital which has more than 1,200 bead. Twenty eight doctors, three nurses, and one technician participated as members of development teams for eight months. Four to six meetings were held, and three to seven departments in the hospital were involved. Results : The topics which developed into clinical practice guidelines were cardiopulmonary resuscitation(CPR), blood transfusion, anticoagulation, and angiography. The main goals set by teams were education(CPR, angiography), risk management(blood transfusion), and to enhance quality of care(anticoagulation). Among four teams, only in the team for anticoagulation guideline medical record review and pilot-testing were performed. Also literature review was not carried out systematically. However, all the guidelines were developed by multidisciplinary be used as standard protocols in the practice. Conclusion : Experience and skill in developing process has to be improved to have a more valid and useful practice guideline. In particular, literature review and problem identification by examining medical record should be emphasized. Also further studies on the clinical outcomes of the guidelines application and changes in physicians' behaviors would be required.

• The Journal of the Korea Contents Association
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• v.14 no.4
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• pp.123-134
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• 2014

Recently, the retro content emerges one of the highest topics in the cultural content area. This retro content has been exponentially expanded through the series of and the success of the series highlights the importance of content that can cause user's emotional experience. Along the line, this research tries to know how the retro contents draw user's emotional experience beyond the role of just user's recall for the past through the Answer me 1994 syndrome. As the result of factorial analysis for the user's emotional experience, five factories were classified: the emotional experiences by music, item, sensory, story and actors exposed in the drama. Also, the five emotional experience factories influence the relations between the viewers and retro content. Specifically, the factories for the emotional experiences are statistically significant to the viewer's satisfaction. They significantly influence the viewer's trust and attachment for the retro content as well. The influence for the emotional experience factors which affect to viewer's satisfaction are music, item, sensory, story, and actors in order. The influence on the trust about the retro content are music, sensory, story, item in order. On the other hand, the emotional experience by actors are not significantly affect to the trust for the retro content. Lastly, The influence for the attachment about the retro content are music, item, actors, sensory, and story in order.

• Journal of Gastric Cancer
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• v.14 no.2
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• pp.87-104
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• 2014

Although gastric cancer is quite common in Korea, the treatment outcome is relatively favorable compared to those in western countries. However, there are currently no Korean multidisciplinary guidelines for gastric cancer. Experts from related societies developed guidelines de novo to meet Korean circumstances and requirements, including 23 recommendation statements for diagnosis (n=9) and treatment (n=14) based on relevant key questions. The quality of the evidence was rated according to the GRADE evidence evaluation framework: the evidence levels were based on a systematic review of the literature, and the recommendation grades were classified as either strong or weak. The applicability of the guidelines was considered to meet patients' view and preferences in the context of Korea. The topics of the guidelines cover diagnostic modalities (endoscopy, endoscopic ultrasound, and radiologic diagnosis), treatment modalities (surgery, therapeutic endoscopy, chemotherapy, and radiotherapy), and pathologic evaluation. An external review of the guidelines was conducted during the finalization phase.

• Journal of Wetlands Research
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• v.17 no.3
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• pp.245-250
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• 2015

We systematically analyzed the Wetland Conservation Action Plan of Gyeongsangnam Province to evaluate conservation status in local government level. Project topics were categorized into 1) wetland infrastructure, 2) wetland conservation and wise use, 3) education and awareness, and 4) conservation framework. From 2010 to 2013, 42 projects (145 cases, 88,899 million won) were implemented by 14 affiliated organizations under Gyeongsangnam Provincial Government. The number of projects and budget size has been decreased over 4 years, besides most of main projects were continued. The budgets were largely used for wetland project of cities and counties. Development and implementation of various conservation projects may have considerable potential values in wetland conservation, while it is still difficult to assess their overall effectiveness in the society. Diverse wetland management practices in Gyeongsangnam Provincial Government have accumulated fundamental practices and knowledge for an effective local conservation. These administrative experiences will further benefit other local government to establish wetland management framework. To accelerate policy diffusion to other local governments, Gyeongsangnam Province needs to promote and share leading experiences and information of wetland conservation. Enhanced local government framework by the legislation at central government will further support country-level management plans and practices.

• Journal of Korean Society of Transportation
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• v.30 no.1
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• pp.45-58
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• 2012

The traditional four-step demand model has limits in that it cannot reasonably reflect the logistic characteristics of freight transportation system. This is likely to cause problems when estimating the effects of logistics facilities. In order to enhance the reliability and availability of the freight demand estimation procedure it is needed to develop freight demand model which takes into account the logistic characteristics of firms. In the late 1990s, a number of researches on freight demand model considering logistics behaviors began in Europe while a few studies in the area have been conducted recently in Korea. This paper reviews recent advances of the freight model developments in the context of logistic behavior consideration. The main topics include 1) commodity classification, 2) P/C(Production- Consumption) estimation, 3) logistics network representation, 4) logistics chain model, and 5) commodity flow survey. In addition, this paper proposes future direction of the freight demand models with respect to the consideration of logistics characteristics.

• Spatial Information Research
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• v.13 no.3 s.34
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• pp.261-281
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• 2005

Geospatial information and technologies are considered as a fundamental element in the foreign advanced e-governments. Integration of e-Government and GIS technology should be an important task for the Korean e-government. Purpose of this study is to propose integration strategies for Korean e-Government and National GIS projects in a GIS perspective. For the successful integration this study analyzes the evolutional stages of e-Government and changes of GIS paradigms in a more comprehensive way. This study hypothesizes that integration of e-Government and GIS can create greater synergic effects fur the improved citizen services and increased efficiency of governmental administration. To verify the hypothesis, cases of advanced e-Governments in the foreign countries and progress of the Korean e-Government projects are compared and integration strategies are suggested. The strategies are as follows: expanded integration of geospatial and text-based information in e-Government for the greater synergic effects, implementation of GIS portal for e-Government, and development of a variety of geospatial information services for easy access and public participation. Most importantly, innovation of the institutional environments can be considered as an essential requirement to enhance and broaden interdepartmental partnerships. To realize the integration strategies suggested, this study presented the future projects under the following 5 topics: 'service', 'integration of information', 'technology', 'organization' and 'infrastructure for integration'. It is expected that results of this study can contribute to the bigger picture of Korean e-Government and the third National GIS master plan in 2006.

• Journal of the Institute of Electronics and Information Engineers
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• v.49 no.9
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• pp.27-34
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• 2012

Today the energy consumption of ICT networks is about 10% of the worldwide power consumption and will be remarkably increased in the near future. For that reason, the energy saving topics of ICT networks are actually studying in various research institutes. This paper studies the possible energy saving methods assuring the QoS of networks on network level. This paper assumed the energy consumption models according to energy profiles of node and link in IP networks. Especially it formulates the energy problem of a minimum energy consumption with various energy profile models and suggests the methods of energy-aware QoS routing under energy saving and network QoS sustaining condition. It shows the large difference of energy saving according to energy profiles and the possibility of energy saving by using the appropriate energy profile model in the simulation experiment. This paper shows that min_used_path(MP) heuristic of energy-aware QoS routing is the excellent method compared with other heuristic methods as view of reduction ratio of nodes and links and energy saving effect under network QoS sustaining condition. As a result, this paper confirms that the min_used_path(MP) heuristic of energy-aware QoS routing can get energy saving and sustaining of network QoS in IP networks.