• Title/Summary/Keyword: research structure

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SOLUTION STRUCTURE AND INTERACTION ON THE CARBOXYL- TERMINAL DOMAIN OF ESCHERICHIA COLI RNA POLYMERASE $\alpha$ SUBUNIT STUDIED BY NMR

  • Jeon, Young-Ho;Tomofumi Negishi;Masahiro Shirakawa;Toshio Yamazaki;Nobuyuki Fujita;Akira Ishihama;Yoshimasa Kyogoku
    • Proceedings of the Korean Biophysical Society Conference
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    • 1996.07a
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    • pp.11-11
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    • 1996
  • The three-dimensional structure of the carboxyl-terminal domain of the E.coli RNA polymerase $\alpha$ subunit, which is regarded as the contact site for transcription activator proteins and the promoter UP element, was determined by NMR spectroscopy. Its compact structure of four helices and two long arms enclosing its hydrophobic core shows a folding topology distinct from those of other DNA-binding proteins. (omitted)

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High Luminous Efficacy AC-PDP with Long Discharge Gap and Grooved Dielectric Structure

  • Lee, Dong-Woo;Choi, Kwang-Yeol;Choi, Sung-Chun;Baek, Dong-Gi;Lim, Jong-Rae;Ahn, Byung-Nam;Park, Won-Bae
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08a
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    • pp.123-126
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    • 2007
  • In this study, a high luminous efficacy AC-PDP panel with long discharge gap and grooved dielectric layer has been studied. By applying this high efficacy concept and optimized driving waveform featuring negative biased sustain, ${\sim}2.6lm/W$ of luminous efficacy was achieved in 42- inch HD panel. Modified fabricating process and new discharge cell structure were investigated to obtain improved uniformity and operating characteristics.

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A Study on Developing a Metadata Search System Based on the Text Structure of Korean Studies Research Articles (한국학 연구 논문의 텍스트 구조 기반 메타데이터 검색 시스템 개발 연구)

  • Song, Min-Sun;Ko, Young Man;Lee, Seung-Jun
    • Journal of the Korean Society for information Management
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    • v.33 no.3
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    • pp.155-176
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    • 2016
  • This study aims to develope a scholarly metadata information system based on conceptual elements of text structure of Korean studies research articles and to identify the applicability of text structure based metadata as compared with the existing similar system. For the study, we constructed a database(Korean Studies Metadata Database, KMD) with text structure based on metadata of Korean Studies journal articles selected from the Korea Citation Index(KCI). Then we verified differences between KCI system and KMD system through search results using same keywords. As a result, KMD system shows the search results which meet the users' intention of searching more efficiently in comparison with the KCI system. In other words, even if keyword combinations and conditional expressions of searching execution are same, KMD system can directly present the content of research purposes, research data, and spatial-temporal contexts of research et cetera as search results through the search procedure.

3-D Hydrogen-Bonded Frameworks of Two Metal Complexes with Chelidamic Acid: Syntheses, Structures and Magnetism

  • Zhou, Guo-Wei;Guo, Guo-Cong;Liu, Bin;Wang, Ming-Sheng;Cai, Li-Zhen;Huang, Jin-Shun
    • Bulletin of the Korean Chemical Society
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    • v.25 no.5
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    • pp.676-680
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    • 2004
  • Complexes M($C_7H_2NO_5)3H_2O{\cdot}H_2O{\cdot}0.25MeCN$ (M=Ni, Co) were crystallized from the reactions of $Ni(CH_3COO)_2{\cdot}4H_2O\;or\;Co(CH_3COO)_2{\cdot}2H_2O$ with KSCN and 2,6-dicarboxy-4-hydroxypyridine (chelidamic acid). The structures were characterized by X-ray crystallography. The crystal structures of 1 and 2 show a distorted octahedral coordination geometry around the M(II) ions, which are chelated by one nitrogen atom and two oxygen atoms of the chelidamic acid and three water molecules. Complexes 1 and 2 display the hydrogen-bonded 3D framework. The magnetic behavior of 2 exhibits antiferromagnetic interaction.

The Intertidal Macrobenthic Community along an Artificial Structure (인공구조물에 따른 조간대 대형저서동물 군집변화)

  • Yu Ok-Hwan;Lee Hyung-Gon;Lee Jae-Hac
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.39 no.spc1
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    • pp.132-141
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    • 2006
  • Artificial structures have been designed as pilot structures to promote the creation and restoration of tidal flats. However, little information is available as to whether such artificial construction affects the macrobenthic community structure. We monitored the variation of the macrobenthic community structure and species composition near natural and artificial structures (seaweed and a timber fence) on the tidal flats near the Iwon Dike, Korea. In total, 137 macrobenthic species were recorded during this study, predominantly crustaceans (47%), polychaetes (18%), and molluscs (27%). Polychaetes comprised over 50% of the total density, followed by gastropods (38%) and crustaceans (11%). Macrobenthic species composition in the artificial and natural areas, was initially similar, but it differed after 7 months. The gastropod Umbonium thomasi, the most dominant species, was present at both sites in the first month after the start of the experiment, but disappeared at the artificial sites within 7 months, suggesting disturbance by the environmental factors. The number of species and diversity (H') varied significantly within sites at the beginning of the experiment, but no difference was observed after 7 months. Multivariate analysis (multidimensional scaling) revealed significant differences in community structure between the artificial and the natural areas from 7 months after the start of the experiment, except from 18 to 21 months. The community structures were mainly influenced by U. thomasi. Community structure at the artificial sites was affected by environmental variables, such as carbon, COD/IL sulfide, loss of ignition, kurtosis and silt, which changed over time. We observed no significant correlations between environmental variables and the dominant species, except in the case of Spio sp. and Macrophthalmus dilatatus, suggesting that the biological interactions and temporary disturbances such as typhoon, as well as the effects of artificial structures may also be important regulating factors in this system.

Crystal Structure of the Regulatory Domain of MexT, a Transcriptional Activator of the MexEF-OprN Efflux Pump in Pseudomonas aeruginosa

  • Kim, Suhyeon;Kim, Songhee H.;Ahn, Jinsook;Jo, Inseong;Lee, Zee-Won;Choi, Sang Ho;Ha, Nam-Chul
    • Molecules and Cells
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    • v.42 no.12
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    • pp.850-857
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    • 2019
  • The Gram-negative opportunistic pathogen, Pseudomonas aeruginosa, has multiple multidrug efflux pumps. MexT, a LysR-type transcriptional regulator, functions as a transcriptional activator of the MexEF-OprN efflux system. MexT consists of an N-terminal DNA-binding domain and a C-terminal regulatory domain (RD). Little is known regarding MexT ligands and its mechanism of activation. We elucidated the crystal structure of the MexT RD at 2.0 Å resolution. The structure comprised two protomer chains in a dimeric arrangement. MexT possessed an arginine-rich region and a hydrophobic patch lined by a variable loop, both of which are putative ligand-binding sites. The three-dimensional structure of MexT provided clues to the interacting ligand structure. A DNase I footprinting assay of full-length MexT identified two MexT-binding sequence in the mexEF-oprN promoter. Our findings enhance the understanding of the regulation of MexT-dependent activation of efflux pumps.

A Procedure for a Strength Assessment of Permanent Means of Access Structure (Permanent Means of Access 강도 평가 방법에 대한 연구)

  • Jang, Beom-Seon;Chung, Sung-Wook;Ko, Dae-En;Chun, Min-Sung;Kim, Ji-Young
    • Journal of the Society of Naval Architects of Korea
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    • v.46 no.1
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    • pp.31-42
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    • 2009
  • Common structural rule (CSR) doesn' t provide any other specific regulations for permanent means of access (PMA) platform structure in a cargo oil tank. The PMA platform is recommended to comply with scantling requirement of local support member. However, it leads to too conservative scantlings compared with actual loads imposed on the platform. This paper proposes a strength assessment procedure for the PMA structure based on a nonlinear ultimate strength. The ultimate strength is evaluated in a sufficiently conservative way. The first linear buckling mode is used as an initial imperfection shape and its magnitude is determined using the definitions of DNV PULS. Since the same imperfection mode as the failure mode of the ultimate limit state is assumed, it can accelerate the failure. Au ultimate strength capacity curve obtained from a series of nonlinear FE analysis is compared with actual stresses calculated by CSR cargo hold analysis.

Elasto-plastic time history analysis of an asymmetrical twin-tower rigid-connected structure

  • Wu, Xiaohan;Sun, Yanfei;Rui, Mingzhuo;Yan, Min;Li, Lishu;Liu, Dongze
    • Computers and Concrete
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    • v.12 no.2
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    • pp.211-228
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    • 2013
  • The structure analyzed in this paper has particular building style and special structural system. It is a rigid-connected twin-tower skyscraper with asymmetrical distribution of stiffness and masses in two towers. Because of the different stiffness between the north and the south towers, the torsion seismic vibration is significant. In this paper, in order to study the seismic response of the structure under both frequent low-intensity earthquakes as well as rare earthquakes at the levels of intensity 7, the analysis model is built and analyzed with NosaCAD. NosaCAD is an nonlinear structure analysis software based on second-development of AutoCAD with ObjectARX. It has convenient modeling function, high computational efficiency and diversity post-processing functions. The deformations, forces and damages of the structure are investigated based on the analysis. According to the analysis, there is no damage on the structure under frequent earthquakes, and the structure has sufficient capacity and ductility to resist rare earthquakes. Therefore the structure can reach the goal of no damage under frequent earthquakes and no collapse under rare earthquakes. The deformation of the structure is below the limit in Chinese code. The time sequence and distribution of damages on tubes are reasonable, which can dissipate some dynamic energy. At last, according to forces, load-carrying capacity and damage of elements, there are some suggestions on increasing the reinforcement in the core tube at base and in stiffened stories.

Extending torsional balance concept for one and two way asymmetric structures with viscous dampers

  • Amir Shahmohammadian;Mohammad Reza Mansoori;Mir Hamid Hosseini;Negar Lotfabadi Bidgoli
    • Earthquakes and Structures
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    • v.25 no.6
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    • pp.417-427
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    • 2023
  • If the center of mass and center of stiffness or strength of a structure plan do not coincide, the structure is considered asymmetric. During an earthquake, in addition to lateral vibration, the structure experiences torsional vibration as well. Lateraltorsional coupling in asymmetric structures in the plan will increase lateral displacement at the ends of the structure plan and, as a result, uneven deformation demand in seismically resistant frames. The demand for displacement in resistant frames depends on the magnitude of transitional displacement to rotational displacement in the plan and the correlation between these two. With regard to the inability to eliminate the asymmetrical condition due to various reasons, such as architectural issues, this study has attempted to use supplemental viscous dampers to decrease the correlation between lateral and torsional acceleration or displacement in the plan. This results in an almost even demand for lateral deformation and acceleration of seismic resistant frames. On this basis, using the concept of Torsional Balance, adequate distribution of viscous dampers for the decrease of this correlation was determined by transferring the "Empirical Center of Balance" (ECB) to the geometrical center of the structure plan and thus obtaining an equal mean square value of displacement and acceleration of the plan edges. This study analyzed stiff and flexible torsional structures with one-way and two-way mass asymmetry in the Opensees software. By implementing the Particle Swarm Optimization (PSO) algorithm, the optimum formation of dampers for controlling lateral displacement and acceleration is determined. The results indicate that with the appropriate distribution of viscous dampers, not only does the lateral displacement and acceleration of structure edges decrease but the lateral displacement or acceleration of the structure edges also become equal. It is also observed that the optimized center of viscous dampers for control of displacement and acceleration of structure depends on the amount of mass eccentricity, the ratio of uncoupled torsional-to-lateral frequency, and the amount of supplemental damping ratio. Accordingly, distributions of viscous dampers in the structure plan are presented to control the structure's torsion based on the parameters mentioned.