• 한국정보디스플레이학회:학술대회논문집
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• 2009.10a
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• pp.322-325
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• 2009

Amorphous oxide semiconductors (AOSs) are expected as new channel materials in TFTs for largearea and/or flexible FPDs, and several prototype displays have been demonstrated in these five years since the first report of AOS TFT. In this paper, we review fundamental materials science of AOSs that have been clarified to date in connection with operation characteristics of AOS TFTs.

• Bulletin of the Korean Space Science Society
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• 2008.10a
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• pp.35.2-35.2
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• 2008

The Albedo MONitor and RAdiometer (AMON-RA) instrument system is designed to measure Earth global albedo anomaly over the wavelength range of 0.3um to 4um. The instrument consists of two interconnecting optical subsystems i.e. a visible channel and an energy channel. The energy channel instrument consists of a modified Winston cone, a couple of relay mirrors and a pyro-electric detector. First, we report the integration and alignment process, leading to the prototype bolometer instrument. We then discuss the radiometric performance characterization including laboratory measurement results and the future plan for further incorporation of the bolometer instrument into the prototype AMON-RA instrument.

• Korean journal of communication and information
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• v.46
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• pp.9-36
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• 2009

In a competitive media environment, Internet Protocol television (IPTV) has gained appeal because of its essential characteristics, 'Internet and Interactivity'. Our study aims to explore predictors that affect IPTV-VOD adoption within the context of competing media (i.e., existing multi-channel video programming services, such as cable television and digital broadcasting satellite services). In addition, this study examines if IPTV-VOD functions as a substitute for existing multi-channel services, such as cable television and direct broadcasting satellite services. A self-report survey through face-to-face interviews was conducted in Seoul metropolitan area and other six big cities. Our findings showed that primary factors for adopting an IPTV-VOD are: age of user, subjective importance of terrestial broadcasting services, real-time terrestrial broadcasting services, and other interactive service characteristics, such as time-shifting. Also, IPTV-VOD services were found to be a substitute for existing multi-channel video programming services.

• Korean Journal of Bronchoesophagology
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• v.18 no.2
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• pp.45-48
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• 2012

Background Neoplastic vessels tend to proliferate on the surface of malignant lesions in the aerodigestive tract. So, superficial malignant lesions can be detected earlier by enhancing mucosal vascular clarity. To enhance mucosal vascular clarity on endoscopic image, we developed an image processing algorithm of RGB (red-green-blue) channel substitution image (CSI). Methods Each pixel in original white light image (WLI) has its own value of red, green and blue channel. Various combinations of RGB channel substitution was tried on original WLI. Results To make superficial blood vessels darker than brighter background mucosa, in the CSI algorithm, RGB value in each pixel of WLI is substituted; red value to green one, green value to blue one. There was a good contrast between superficial mucosal vessels and background brighter mucosa in the CSI image. Conclusion By RGB CSI algorithm, WLI could be successfully converted to new images with enhanced mucosal vascular clarity. Using RGB CSI algorithm could provide added vascular visibility on original WLI.

• The Korean Journal of Physiology and Pharmacology
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• v.27 no.5
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• pp.481-491
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• 2023

The β subunits of high voltage-gated calcium channels (HGCCs) are essential for optimal channel functions such as channel gating, activation-inactivation kinetics, and trafficking to the membrane. In this study, we report for the first time the potent blood pressure-reducing effects of peptide fragments derived from the β subunits in anesthetized and non-anesthetized rats. Intravenous administration of 16-mer peptide fragments derived from the interacting regions of the β1 [cacb1(344-359)], β2 [cacb2(392-407)], β3 [cacb3(292-307)], and β4 [cacb4(333-348)] subunits with the main α-subunit of HGCC decreased arterial blood pressure in a dose-dependent manner for 5-8 min in anesthetized rats. In contrast, the peptides had no effect on the peak amplitudes of voltage-activated Ca²⁺ current upon their intracellular application into the acutely isolated trigeminal ganglion neurons. Further, a single mutated peptide of cacb1(344-359)-cacb1(344-359)_K357R-showed consistent and potent effects and was crippled by a two-amino acid-truncation at the N-terminal or C-terminal end. By conjugating palmitic acid with the second amino acid (lysine) of cacb1(344-359)_K357R (named K2-palm), we extended the blood pressure reduction to several hours without losing potency. This prolonged effect on the arterial blood pressure was also observed in non-anesthetized rats. On the other hand, the intrathecal administration of acetylated and amidated cacb1(344-359)_K357R peptide did not change acute nociceptive responses induced by the intradermal formalin injection in the plantar surface of rat hindpaw. Overall, these findings will be useful for developing antihypertensives.

• Journal of Embryo Transfer
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• v.19 no.2
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• pp.101-112
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• 2004

Chloride($Cl^-$) channels play critical roles in cell homeostasis and its specific functions such as volume regulation, differentiation, secretion, and membrane stabilization. The presence of these channels have been reported in all kinds of cells and even in frog oocytes. These essential role of $Cl^-$­ channels in cell homeostasis possibly play any role in egg homeostasis and in the early stage of development, however, there has been no report about the presence of $Cl^-$­ channel in the mammalian oocyte. This study was performed to elucidate the presence of $Cl^-$­ channels in hamster eggs. When allowing only $Cl^-$­ to pass through the channel of the egg membrane by using impermeant cation such as N-methyl-D-glucamine(NMDG), single channel currents were recorded. These channel currents showed typical long-lasted openings interrupted by rapid flickering. Mean open $time({\tau}o)$ was 43${\pm}$10.14 ms(n=9, at 50 mV). The open probability(Po) was decrease with depolarization. The current-voltage relation showed outward rectification. Outward slop conductance(32${\pm}$5.4 pS, n=22) was steeper than the inward slop conductance(10${\pm}$1.3 pS). Under the condition of symmetrical 140 mM NaCl, single channel currents were reversed at 0 mV(n=4). This reversal potential(Erev) was shifted from 0 mV at 140 mM concentration of internal NaCl(140 mM [Na+]i) to ­9.8${\pm}$0.5 mV(n=4) at 70 mM [Na+]i and 11.5${\pm}$1.9 mV at 280 mM [Na+]i(n=4) respectively, strongly suggesting that these are single $Cl^-$­ channel currents. To examine further whether this channel has pharmacological property of the $Cl^-$­ channel, specific Cl­ channel blockers, IAA-94(Indanyloxyacetic acid-94) and DIDS(4, 4'-diisothiocyan ostillben- 2-2'disulfonic acid) were applied. IAA-94 inhibited the channel current in a dose-dependent manner and revealed a rapid and flickering block. From these electrophysiological and pharmacological resluts, we found the novel $Cl^-$­ channel present in the hamster oocyte membrane. The first identification of $Cl^-$­ channel in the hamster oocyte may give a clue for the further study on the function of $Cl^-$­ channel in the fertilization and cell differentiation.

• Journal of Ginseng Research
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• v.35 no.2
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• pp.191-199
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• 2011

The human ether-a-go-go-related gene (HERG) cardiac $K^+$ channels are one of the representative pharmacological targets for development of drugs against cardiovascular diseases such as arrhythmia. Panax ginseng has been known to exhibit cardioprotective effects. In a previous report we demonstrated that ginsenoside $Rg_3$ regulates HERG $K^+$ channels by decelerating deactivation. However, little is known about how ginsenoside metabolites regulate HERG $K^+$ channel activity. In the present study, we examined the effects of ginsenoside metabolites such as compound K (CK), protopanaxadiol (PPD), and protopanaxatriol (PPT) on HERG $K^+$ channel activity by expressing human a subunits in Xenopus oocytes. CK induced a large persistent deactivatingtail current ($I_{deactivating-tail}$) and significantly decelerated deactivating current decay in a concentration-dependent manner. The $EC_{50}$ for persistent $I_{deactivating-tail}$ was $16.6{\pm}1.3$ ${\mu}M$. In contrast to CK, PPT accelerated deactivating-tail current deactivation. PPD itself had no effects on deactivating-tail currents, whereas PPD inhibited ginsenoside $Rg_3$-induced persistent $I_{deactivating-tail}$ and accelerated HERG $K^+$ channel deactivation in a concentration-dependent manner. These results indicate that ginsenoside metabolites exhibit differential regulation on Ideactivating-tail of HERG $K^+$ channel.

• Journal of Forest and Environmental Science
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• v.12 no.1
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• pp.13-25
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• 1996

In recent erosion control works, securing not only the disaster prevention space but the environmental space, harmonized with surrounding environment and abundant with biological resources, are emphasized. Inspired of by the fact that efforts to secure such spaces have been being briskly promoted in Japan since the beginning of 1990s', we compile and analyze the Japanese sources about the "environmentally-sound erosion control works" to contribute to the erosion control works of our country. Specifically, in this report, we deal with the subjects of "establishment of the comfortable river environment" and "environmentally-sound erosion control works" which includes "erosion control dam", "water channel works and revetments", "fish routes" and "water quality conservation works".

• The Journal of Internal Korean Medicine
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• v.38 no.2
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• pp.259-263
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• 2017

We describe the cases of two patients with chronic subdural hematomas who were treated with Oreong-san. The patients' symptoms improved, as verified by brain computed tomography imaging. Oreong-san may control membrane permeability by inhibiting the aquaporin channel of the outer membrane of a hematoma. We speculate that hydrostatic modulation is a key mechanism underlying the effectiveness of Oreong-san in the treatment of subdural hematomas.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.24 no.2
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• pp.152-155
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• 2011

Even though nano-scale materials were very advantageous for various applications, there are still problems to be solved such as the stabilization of surface state and realization of low contact resistances between a semiconducting nanowire and electrodes in nano-electronics. It is well known that the effects of contacts barrier between nano-channel and metal electrodes were dominant in carrier transportation in individual nano-electronics. In this report, it was investigated the electrical properties of GaN nanorod devices after chemical etching and rapid thermal annealing for making good contacts. After KOH wet-etching of the contact area the devices showed better electrical performance compared with non-treated GaN individual devices but still didn't have linear voltage-current characteristics. The shape of voltage-current properties of GaN devices were improved remarkably after rapid thermal annealing as showing Ohmic behaviors with further bigger conductivities. Even though chemical etching of the nanorod surfaces could cause scattering of carriers, in here it was shown that the most important and dominant factor in carrier transport of nano-electronics was realization of low contact barrier between nano-channel and metal electrodes surely.