• 제목/요약/키워드: repeated measures data

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불완전한 반복측정 자료의 보정방법 (Methods for Handling Incomplete Repeated Measures Data)

  • 우해봉;윤인진
    • 한국조사연구학회지:조사연구
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    • 제9권2호
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    • pp.1-27
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    • 2008
  • 사회조사 자료를 활용한 통계분석에 있어서 불완전 자료의 문제는 거의 모든 연구자들이 경험하는 하나의 보편적인 문제이다. 불완전 자료의 문제는 특히 패널조사와 같은 종단적 자료를 활용한 연구에 있어서 중요한 이슈가 된다. 본 연구의 목적은 최근까지 이루어진 불완전 자료에 대한 보정방범을 소개하는 것이다. 특히, 본 연구는 패널자괴에서 발생한 불완전 자료의 처리에 대한 관심이 부족한 점을 고려하여 최근까지 이루어진 보정방법들을 반복측정 패널자료 분석에 적용하는데 초점을 맞춘다. 첫째, 본 연구는 불완전 자료에 대한 적절하지 못한 사후처리는 분석결과에 있어서 유의미한 차이로 이어 수 있음을 시사한다. 특히, 분석결과는 반복측정 자료를 사용하는 연구의 경우 불완전 자료의 발생은 궤적의 초기값보다는 시간의 경과에 따른 궤적의 변화를 적절히 추정하는데 문제를 가질 수 있음을 시사하고 있다. 둘째, 분석결과는 완전제거법이나 평균대체법이 EM, FIML, MICE 방법들에 비해 불완전 자료의 처리효과가 상대적으로 떨어짐을 보여준다. 특히, 완전제거법이나 평균대체법과 같은 방법에 비해 최대우도법이나 다중대체법이 갖는 상대적 우위는 MCAR 가정에 비해 보다 현실적인 가정이라고 할 수 있는 MAR 조건하에서 크게 나타난다. 본 연구의 분석결과는 또한 비록 결측치의 발생기제가 MNAR 상황이라고 하더라도 연구자가 결측치의 발생과 관련된 변수들을 보정과정에서 적절하게 활용하면 편의의 상당부분을 감소시킬 수 있음을 시사한다.

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집단미술치료가 암병동 간호사의 직무스트레스와 소진에 미치는 효과 (The Effects of a Group Art Therapy on Job Stress and Burnout among Clinical Nurses in Oncology Units)

  • 장옥점;류의정;송현정
    • 임상간호연구
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    • 제21권3호
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    • pp.366-376
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    • 2015
  • Purpose: The purpose of this study was to evaluate the effects of a group art therapy on decreasing job stress and burnout of clinical oncology nurses. Methods: The study was conducted using a non-equivalent control group, non-synchronized design with repeated measures. A total of 29 clinical oncology nurses participated in the study; 15 were assigned in the experimental group, and 14 in the control group. Data were collected from May to July, 2014. The study questionnaires were administered in three different time points (pretest, 8th week, and 12th week). Data were analyzed using $x^2-test$, Fisher's exact test, t-test, paired t-test, and repeated measures ANOVA. Results: The first hypothesis "the experimental group with group art therapy will have lower job stress than that of the control group" was support (F=7.88, p=.003). The second hypothesis, "the experimental group will have lower burnout than that of the control group" was not statistically supported (F=1.80, p=.188). Conclusion: The findings of the study indicated that the group art therapy for oncology nurses may positively influence in decreasing job stress, which open a venue for developing a nursing intervention with group art therapy for clinical nurses in future.

Property of regression estimators in GEE models for ordinal responses

  • Lee, Hyun-Yung
    • Journal of the Korean Data and Information Science Society
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    • 제23권1호
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    • pp.209-218
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    • 2012
  • The method of generalized estimating equations (GEEs) provides consistent esti- mates of the regression parameters in a marginal regression model for longitudinal data, even when the working correlation model is misspecified (Liang and Zeger, 1986). In this paper we compare the estimators of parameters in GEE approach. We consider two aspects: coverage probabilites and efficiency. We adopted to ordinal responses th results derived from binary outcomes.

간호학생 대상 시뮬레이션기반 기본소생술 반복교육의 효과와 지속성 (Effectiveness and Retention of Repeated Simulation-based Basic Life Support Training for Nursing Students)

  • 정지수;허혜경
    • 중환자간호학회지
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    • 제6권2호
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    • pp.24-36
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    • 2013
  • Propose: This study was to investigate the educational effect and retention of repeated simulation-based basic life support (BLS) training for nursing students. Methods: A comparison group design with pretest and posttest was used. A total of 35 nursing students (18 for the experimental group, 17 for the control group) participated in the study. A repeated simulationbased BLS training program which include a lecture, skills training, and two repeated sessions of simulation practice and debriefing was provided twice for experimental group. Knowledge, self-efficacy, and skill performance of cardiopulmonary resuscitation (CPR) were measured three times: at baseline, week 2, and week 6. Descriptive analysis, repeated measures ANOVA, and t-test were used for data analyses. Results: Knowledge, self-efficacy and skill performance of CPR were not significantly changed by group assignment, by the time, and interaction of group by time. Effectiveness of intervention was not maintained until Week 6. Conclusion: The results suggest that the timing of repeat education, total training time, and students' mastery of CPR performance should be considered when developing simulation-based programs to improve and maintain students' CPR knowledge, self-efficacy, and skill performance.

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선형혼합모형을 활용한 생물학적 동등성 분석 (Bio-Equivalence Analysis using Linear Mixed Model)

  • 안형미;이영조;유경상
    • 응용통계연구
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    • 제28권2호
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    • pp.289-294
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    • 2015
  • 생동성 시험과 같은 임상약리학분야의 연구는 일반적으로 한 개체 내에서 반복하여 측정된 자료구조를 사용하므로 선형혼합모형을 이용하여 분석하는 것이 보편적이다. 이러한 모형에서 랜덤효과는 개체 내 관측 자료 사이의 상관관계를 설명하고, 공분산행렬은 개체-내 변동을 설명한다. 생동성 분석은 두 약물의 약동학적 변수인 Cmax와 AUC의 기하평균비에 대한 90% 신뢰구간이 동등성 한계인 [0.8, 1.25] 범위에 드는지 알아보는 분석으로, 고정효과에는 시기, 순서군, 치료효과를, 랜덤효과에는 개체효과를 가지는 선형혼합모형을 이용하여 분석한다. 이러한 분석이 적용된 실제 예를 살펴보기 위하여 레보플록사신 연구의 자료를 활용하였다.

Robustness for Pairwise Multiple Comparison Procedures with Trimmed Means under Violated Assumptions : Bonferroni, Shaffer, and Welsch Procedure

  • Kim, Hyun-Chul
    • Communications for Statistical Applications and Methods
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    • 제4권3호
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    • pp.775-785
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    • 1997
  • Robustness rates for repeated measures pairwise multiple comparison procedures were investigated in a split plot design with one between- and one within-subjects factor using untrimmed and trimmed data. Five factors were manipulated in the study: distribution, sphericity, variance-covariance heteroscedasticity, total sample size, and sample size ratio. The Welsch test (W) and the Welsch test on trimmed data $(W_{RT})$ performed better than the other procedures, but had a liberal tendency. The trimmed difference score Bonferroni Procedure $(B_{DT})$ was a good choice in some conditions.

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A Study on Decision Tree for Multiple Binary Responses

  • Lee, Seong-Keon
    • Communications for Statistical Applications and Methods
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    • 제10권3호
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    • pp.971-980
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    • 2003
  • The tree method can be extended to multivariate responses, such as repeated measure and longitudinal data, by modifying the split function so as to accommodate multiple responses. Recently, some decision trees for multiple responses have been constructed by Segal (1992) and Zhang (1998). Segal suggested a tree can analyze continuous longitudinal response using Mahalanobis distance for within node homogeneity measures and Zhang suggested a tree can analyze multiple binary responses using generalized entropy criterion which is proportional to maximum likelihood of joint distribution of multiple binary responses. In this paper, we will modify CART procedure and suggest a new tree-based method that can analyze multiple binary responses using similarity measures.

Practical statistics in pain research

  • Kim, Tae Kyun
    • The Korean Journal of Pain
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    • 제30권4호
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    • pp.243-249
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    • 2017
  • Pain is subjective, while statistics related to pain research are objective. This review was written to help researchers involved in pain research make statistical decisions. The main issues are related with the level of scales that are often used in pain research, the choice of statistical methods between parametric or nonparametric statistics, and problems which arise from repeated measurements. In the field of pain research, parametric statistics used to be applied in an erroneous way. This is closely related with the scales of data and repeated measurements. The level of scales includes nominal, ordinal, interval, and ratio scales. The level of scales affects the choice of statistics between parametric or non-parametric methods. In the field of pain research, the most frequently used pain assessment scale is the ordinal scale, which would include the visual analogue scale (VAS). There used to be another view, however, which considered the VAS to be an interval or ratio scale, so that the usage of parametric statistics would be accepted practically in some cases. Repeated measurements of the same subjects always complicates statistics. It means that measurements inevitably have correlations between each other, and would preclude the application of one-way ANOVA in which independence between the measurements is necessary. Repeated measures of ANOVA (RMANOVA), however, would permit the comparison between the correlated measurements as long as the condition of sphericity assumption is satisfied. Conclusively, parametric statistical methods should be used only when the assumptions of parametric statistics, such as normality and sphericity, are established.

건강한 여성의 하이힐 계단오르기 보행이 안쪽빗넓은근과 가쪽넓은근의 근활성비와 개시시간에 미치는 영향 (Effects of Shoe Heel Height on the Onset of VMO Relative to VL and VMO/VL EMG Ratio during Stair Ascent in Women without Knee Pathology)

  • 김현희;송창호
    • 대한물리의학회지
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    • 제6권2호
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    • pp.135-143
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    • 2011
  • Purpose: The purpose of this study was to investigate onset timing of vastus medialis oblique(VMO) relative to vastus lateralis(VL) the VMO/VL electromyographic(EMG) ratio according to heel height Methods: A repeated measures design was used. Fifteen healthy female college students with no known knee musculoskeletal dysfunction were recruited this study. They carried out a standardised stair acent activity under 4 conditions; barefoot, and with heel height of 1, 3, 7 cm. Muscle activity was measured by surface EMG (Myosystem 1400A, Noraxon Inc., U.S.A). Data were analysed using $1{\times}4$ repeated measures ANOVA. Results: Onset timing differed with heel height(p<.05). However, the VMO/VL EMG ratio was not significantly difference between conditions. Conclusion: We found that 7 cm heel height delayed in VMO onset compared with 3 cm heel height during stair ascent, but no change in the relative EMG intensity of VMO and VL as measured by th VMO/VL ratio. The findings indicate that high-heeled shoes may have disadvantages in knee stability because of delayed onset of VMO. Due to a lack of knee joint stability, wearing of high heeled shoes should be avoided.

식후저혈압 위험 노인의 식전 물 섭취가 식후 혈압변화에 미치는 효과 (Effect of Water Drinking on the Postprandial Fall of Blood Pressure in the Elderly)

  • 손정태;이은주
    • 기본간호학회지
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    • 제17권3호
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    • pp.304-313
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    • 2010
  • Purpose: The purpose of this study was to examine preventive effects of water drinking on postprandial fall of blood pressure in the elderly. Method: Participants were 25 elders who had experienced postprandial fall of systolic blood pressure of more than 15mmHg in a previous study. Within subject repeated measures design using random order allocation was used to control extraneous variables among participants. During the experiment, each participant had to drink 400mL water before lunch, whereas when in the control, they only had their lunch. Blood pressure and heart rate were measured for both times before lunch and at 15 minutes intervals up to 90 minutes after lunch. Data were analyzed using descriptive statistics, repeated measures of ANOVA, paired t-test and Bonferroni adjustment as Post-hoc analysis. Results: Water drinking before lunch elicited significant pressor effects by increasing systolic and diastolic pressure $13.9{\pm}4.7/5.2{\pm}2.2mmHg$ compared blood pressure during the control p<.005, p<.022. Heart rate, however, did not change significantly at either time. Conclusion: Drinking water before meal is recommended for elders who experience postprandial hypotension. However, the appropriate volume of water to prevent postprandial fall in blood pressure should be further studied.