• Journal of Genetic Medicine
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• v.1 no.1
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• pp.23-26
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• 1997

Myotonic dystrophy (DM) is caused by the expansion of CTG trinucleotide repeat near the 3' end of the gene encoding for a member of protein kinase gene family (DMPK). The normal range of the CTG repeat was determined in 178 normal individuals (141 unrelated individuals and 37 of 9 families) by polymerase chain reaction (PCR), polyacrylamide gel electrophoresis and silver staining method. And the expansion of the CTG repeats in a DM family was analyzed with Southern analysis. In normal population, the range of CTG repeat is between 5 and 34 and 19 different alleles were observed in that range, and $(CTG)_{11-14}$ alleles were predominant. 4 members of an affected family showed the 0.5-2.0 kb size expansion of CTG repeats. In this study we could predict the incidence of DM in Korea as 1 in 20,000 and we could establish the diagnostic procedure for myotonic dystrophy.

• Journal of Institute of Control, Robotics and Systems
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• v.22 no.10
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• pp.869-875
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• 2016

In this paper, a novel scheme with which to mitigate a repeat-back jamming effect is proposed for the GPS L1 coarse/acquisition signal. The proposed scheme estimates the code tracking bias caused by repeat-back jamming signals using a Combined Pseudo-random noise signal. It then mitigates the repeat-back jamming effect by subtracting the estimated code timing on a normal correlation channel from the estimated value. Through a Monte-Carlo simulation, the proposed scheme can diminish the running average of code tracking bias to less than 10% of the bias using the conventional scheme.

• Journal of Embryo Transfer
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• v.12 no.1
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• pp.117-122
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• 1997

The objective of this study was to enhance the pregnancy rate of repeat-breeder Hanwoo with gonadotropin-releasing hormone(Gn-RH) at the time, dose and site of administration.The results obtained were summaried as fallows:1.Ovulation time and pregnancy rate following GnRH administration time was 46.0, 27.4, 42.0 and 43.2hr and 33.3, 57.1, 37.5 and 40.0% at non-treatment, estus, 1st A' and 2nd Al treatment, respectively.2. Ovulation in repeat-breeder was induced 100% within 24hr with GnRH administration at the time of estrus.3. Ovulation time and pregnancy rate following GnRH adminstration dose and site was 25.2, 32.6, 17.6 and 27.6hr, and 28.6, 42.9, 75.0 and 66.7% at 50$\mu$g+IU, 50$\mu$g+IM, 100$\mu$g+IU and 100$\mu$g+IM treatments, respectively. It is concluded that GnRH administration for repeat-breeder was enhanced the pregnancy rate when treated with 100$\mu$g intrauterine at the time of estrus.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.16 no.2
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• pp.199-210
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• 2005

Objective : Attention deficit hyperactivity disorder(ADHD) affects $5-10\%$ of children in Korea, with more boys and girls being diagnosed. Despite seriousness of ADHD, little is known about its causes. From the current genetic epidemiologic studies, ADHD is known as a heritable disorder. Till now, however, there have been very few genetic studies about ADHD in Korea. The aim of the this study is to examine the association between dopamine transporter gone type 1 and ADHD using case-control design in Korean ADHD probands and normal controls. Materials and Method : Child Psychiatric Genetic research team in Seoul National University Hospital, Clinical Research Institute recruited the ADHD probands using clinical interview/observation, diverse rating scales, and neuropsychological tests. For eliminating phenocopy or ADHD, diagnosis of ADHD was based upon clinical data, psychometric data, and parent/teacher reports. Total 85 ADHD-probands were recruited as final study subjects and independent 100 normal adults participated in this study as control group. For all the ADHD probands, and controls, the 3'-UTR-VNTR polymorphism of DAT1 was analyzed. Based on the DAT1 allele and genotype informations, Chi-square test based on case-control design was performed. Results : As for genetic study, total of 85 probands and 100 controls were included for the genetic analysis. Four different alleles, 350bp (7repeat), 440bp (9repeat), 480bp (10repeat) and 520bp (11repeat) were found in DAT1 gene of study subjects. In case-control analysis, ADHD probands and parents have significantly more 9 repeat allele and 9/10 genotype. Also, The probands with 9repeat allele have more commission errors in ADS. Conclusion : The positive association between ADHD and DAT1 gene was replicated in this report like other previous results for caucasian children and Korean children with ADHD. There are ongoing studies on other candidate genes such as DRD4 and DRD5 and it would be required to explore the association of these candidate genes in Korean children with ADHD. These ongoing genetic research will contribute to the understanding of heterogenous genetic and environmental etiologies of ADHD phenotype, which will lead to the development of more comprehensive treatment and preventive interventions for ADHD.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2004.04a
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• pp.160-165
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• 2004

At this research, we examined probability of light bulb's life span value and prediction on purpose to inquire out the span of repeat velocity as fracture probability by executing the fatigue test, which is considered property of Tungsten filament's thermal fatigue used as an automobile bulb. As a result we can confirm what the most suitable solution is weibull distribution and log normal distribution. Tungsten filament's span gets longer as the fatigue repeat velocity gets shorter And, repeat span is about 15%~40% shorter than sequence life span.

• Journal of Korean Institute of Industrial Engineers
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• v.11 no.2
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• pp.19-27
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• 1985

Optimal numbers of repeat inspections are obtained for a single inspector who has a fixed probability of detecting a nonconforming item on each inspection and will continue to inspect until further inspection is not warranted when comparing the expected increase of total gain with the inspection cost. It is assumed that the detection probability decreases as the number of repeat inspections increases, and that the lot to be inspected contains an unknown but Poisson distributed number of nonconforming items.

• Journal of The Korean Radiological Technologist Association
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• v.28 no.1
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• pp.178-185
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• 2002

This study was performed to investigate radiographic repeat rate on QC factors and to compare numbers of repeat film according to each year radiogical technologist. I wanted to make basic data to use QC programs in department of diagnostic radiology. This

• Annals of Clinical Neurophysiology
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• v.6 no.1
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• pp.61-63
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• 2004

The copy numbers of the CTG repeats are known to relate to the severity of clinical symptoms for myotonic dystrophy. The positive correlation between clinical manifestations and CTG repeat size has been demonstrated previously. A genetically confirmed myotonic dystrophy patient with 90 CTG repeat number had more severe clinical manifestation than brother with 120 CTG repeats, in adulthood.

• Journal of Embryo Transfer
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• v.17 no.3
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• pp.235-238
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• 2002

The present study was undertaken to find out possibilities for superovulation and recovery of freezable/transferable embryo from repeat breeding crossbred cows. For this study a total of 10 Holstein crossbred cows having history of failure of conception even after more than 4~5inseminations were taken and superovulated using Folltropin-V at 100 to 140% dose schedule. The results indicated that out of 10 donors, 8 responded to superovulatory treatment and yielding a total of 94 embryos, out of which 45 were of transferable/freezable quality. The mean ovulations and mean transferable embryos were 11.5$\pm$2.91 and 4.5$\pm$1.66, respectively. These observations suggests that the repeat breeding cows having conception failure after several artificial inseminations can be used as donors for production of embryos and calves through embryo transfer technology.

• Proceedings of the KSR Conference
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• 2001.10a
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• pp.520-525
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• 2001

It's strongly recommended to check upon the slope stability of soil nearby railroad, since the freezing-thawing repeat in long term may cause decrease of slope stability. The study is, therefore, focused on the strength characteristic transformation of soil, measuring it experimentally, throughout physical and mechanical tests operated by the freezing-thawing repeat tests. The sampling of weathered soil used for the embankment materials along the domestic railway lines are classified by parent-rock, and then collected after it in the first hand. It tells that Uniaxial strength and axial strain were decreased simultaneously as the frequency of freezing-thawing repeat increased and its range was reduced into 25～85 percentage off comparing to uniaxial strength of unfreezing-soils when about 100 times of freezing-thawing repeats occurred. Following the result of direct shear tests, the cohesion of freezing-soil with freezing-thawing repeats shows 11∼60 percentage less than that of unfreezing-soil but the change of internal friction angle of the soil is extremely slight, enough to ignore. As a result. it could be found that strength characteristic transformation has highly correlated with freezing-thawing repeat.