• 한국임상약학회지
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• 제15권2호
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• pp.139-148
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• 2005

Appropriate drug classification is important fur rational drug consumption. This study was conducted to evaluate the appropriateness of current drug classification system and suggest possible ways for improving the system. Nonprescription drug market has been decreased. Since total 27,962 products had been classified (prescription 17,187 vs. nonprescription 10,775 products, 61.5% vs. 38.5%) in July 2000 for implementing separation of drug prescribing and dispensing system, there are no classification changes. Reclassification is not motivated by product holder and regulatory system did not lead classification change either. Consumers' ease access to some nonprescription drugs is demanded. But point of public awareness and cultural and health environmental views, saff drug use rather than advantages from broad supply of nonprescription drugs is more critical. We concluded that current 2-categorized (prescription and nonprescription) drug classification system is appropriate, and addition of general sale category should be approached carefully with long term Preparations such as establishment of better nonprescription drug consuming infrastructure by public information provision and education for improving public medicinal knowledge and strengthening self medication guidance, and review of current classification status of marketed drugs and switching possibilities. For systemizing and encouraging reclassification, introduction of regulatory renewal system as a continuous reevaluation program which is the best way to review appropriateness of drug classification as well as provision of detailed guidance for industry including policy, requirement and process fer reclassification application, are necessary.

• Asian Pacific Journal of Cancer Prevention
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• 제14권10호
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• pp.5579-5587
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• 2013

Research indicates that a small population of cancer cells is highly tumorigenic, endowed with the capacity for self-renewal, and has the ability to differentiate into cells that constitute the bulk of tumors. These cells are considered the "drivers" of the tumorigenic process in some tumor types, and have been named cancer stem cells (CSC). Epithelial-mesenchymal transition (EMT) appears to be involved in the process leading to the acquisition of stemness by epithelial tumor cells. Through this process, cells acquire an invasive phenotype that may contribute to tumor recurrence and metastasis. CSC have been identified in human head and neck squamous cell carcinomas (HNSCC) using markers such as CD133 and CD44 expression, and aldehyde dehydrogenase (ALDH) activity. Head and neck cancer stem cells reside primarily in perivascular niches in the invasive fronts where endothelial-cell initiated events contribute to their survival and function. Clinically, CSC enrichment has been shown to be enhanced in recurrent disease, treatment failure and metastasis. CSC represent a novel target of study given their slow growth and innate mechanisms conferring treatment resistance. Further understanding of their unique phenotype may reveal potential molecular targets to improve therapeutic and survival outcomes in patients with HNSCC. Here, we discuss the state-of-the-knowledge on the pathobiology of cancer stem cells, with a focus on the impact of these cells on head and neck tumor progression, metastasis and recurrence due to treatment failure.

• 대순사상논총
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• 제17권
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• pp.113-134
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• 2004

According to Hans Kippenberg, the foundation of an academic study of religions coincided with the beginnings of modernization. Since the second half of the nineteenth century most European countries were involved in a process of rapid social change. The repercussions that this had for daily life were momentous. Instead of working for their traditional needs, people now had to produce goods for a market. Old customs ceded to private contracts and political laws. The superior knowledge of science replaced the inherited worldview. This deep changed severed societies from their ties to the past. Many educated people in Europe believed in an imminent end of all religions. Had not the scientific progress superseded the religious worldview? Historians had to come to terms with that expectation when they directed their attention to historical religions. Friedrich Max Muller introduced a new science, so-called Religionswissenschaft through the study of the ancient Vedic sources. He thought that genuine religion was a taste for, and sense of, the infinite. From his point of view, the Indian sources confirm that nature is more than mechanical laws. Thus his interpretation sought to contradict the materialist ideology of his day. Edward Burnett Tylor described religions as a kind of natural philosophy. His notion of 'soul' functioned to explain natural events. This legacy of the past cannot be missed even in modern society. Only the concept of the soul may preserve human dignity in an age of materialism. Gerardus van der Leeuw, also tried to perform the same function of the cultural critique for the renewal of the religious imagination in modern, rationalized Europe imprisoned in the iron-cage. In this respect, we could think that the interpretations of the history of the History of Religions in the light of the intellectual history are very suggestive for the korean student of religion. It helps them to describe the early history of the study of religion in Korea. For example, Yi Neung Wha(李能和) is regarded as 'a father of korean religious studies, but no one could present a proper answer for the question of why and through which connection of his intellectual milieu he was interested in the religious history and the study of religion. We would discover its signification in his confrontation of the prevailing social thought, such as social evolutionism.

• 한국간호교육학회지
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• 제6권2호
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• pp.171-185
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• 2000

The twenty-first century may be said to be entering into a specialized qualification age to meet the needs of new technical innovations such as environmental changes, demographical changes, changes in the constitution of diseases, changes in the needs of the national health, reforms of information and knowledge, etc., which requires the provision of competitive services that can fulfill the high level needs of consumers. In consequence, it is needed to apply a practical nursing model that can serve as a guide for healthy society and to secure the sphere that can affect nursing policy-making by keeping pace with the changing environment. Furthermore, it is also urgent to expand more the activity sphere of nurse specialists with authority and autonomy, establish their legal foundation, establish a qualification accreditation system for nurse specialists, and develop educational programs. In Korea, the law relative to organ transplant past the national assembly on February 9, 2000, legally acknowledged brain death, which indicated to us the emergence of an age of organ transplant. Therefore, it necessitates to find out those of brain death from whom organ transplant is feasible in clinical practices, with their families' consent link to those terminal organ failure patients who are in need of an organ, and mediate both parties so that smooth transplant can be accomplished. A series of these complicated procedures require systematically trained specialists with high level techniques of organic management. With this in mind, this study was conducted on 69 clinical nurse specialists for organ transplant, accredited by the hospital, who are in active service in clinical practices. The resultant findings were revealed, as follows: 1. The qualifications of clinical nurse specialists for organ transplant should be accredited by Ministry of Health and Welfare or Korea Nurses Association. 2. The validity of qualifications should be for three years, and their renewal should be based on marks of a supplemental training or an education course for more than 12 hours a year. 3. The qualification of the clinical nurse specialist necessitates theoretical lectures and practices on those nurses who have had clinical experience in the pertinent field. 4. The course of training is required to be one year in the length of training and take more than 20 credits (320 hours) and 5 credits (240 hours).

• Human Ecology Research
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• 제60권3호
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• pp.331-344
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• 2022

The purpose of this study was to identify a support method for the introduction of metaverse-based classes (MBC) in home economics (HE) education. This was achieved by diagnosing the stages of concern and levels of use exhibited by HE teachers applying the concerns-based adoption model (CBAM). Questionnaires were sent to a convenience sample of middle- and high-school HE teachers using the KSDC (Korea Social Science Data Center). Overall, 271 responses were received, and the data were analyzed using KSDC E-STAT 3.0 and SPSS 28.0.1.1. The results were as follows: First, regarding the level of knowledge of MBC, the introductory level was the most common (139 respondents, 51.3%,), followed by the beginner level (81, 29.9%), the intermediate level (28, 10.3%,), the advanced level (12, 4.4%), and the master level (11, 4.1%). Average responses on a 5-point Likert scale to questions about the use of metaverse in HE classes were as follows: possibility (4.02), necessity (3.82), and usefulness (3.90). Second, HE teachers' stages of concern in MBC were as follows (in descending order): unconcerned - stage 0, and information - stage 1 (86.9), personal - stage 2 (85.6), management - stage 3 (80.9), collaboration - stage 5 (57.5), consequence - stage 4 (57.4), and refocusing - stage 6 (55.2). Third, the use of MBC was highest for orientation - level 1 (173 respondents, 63.8%), followed by non-use - level 0 (34, 12.5%), preparation - level 2 (29, 10.7%), mechanical - level 3 (15, 5.5%), refinement - level 5 (8, 3.0%), renewal - level 7 (8, 3.0%), routine - level 4 (3, 1.1%), and integration - level 6 (1, 0.4%). Many HE teachers had heard about MBC but were in the introductory level of not knowing what it is, and at the stage of being unconcerned or wanting to know about MBC. Of the 271 respondents, only 35 used metaverse in classes. Therefore, it is necessary to provide teacher training opportunities that provide basic information on the significance and implementation of MBC for HE teachers. Also, an MBC guideline book should be developed and distributed to HE teachers. Finally, a teacher community meeting is needed to share the expertise of teachers with substantial experience in using MBC.

• 심성연구
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• 제38권1호
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• pp.161-200
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• 2023

본 민담 '임금님 귀는 당나귀 귀'는 왕의 당나귀 귀가 이발사에 의해 발견되고, 그 비밀을 발설하지 못해 병이 난 이발사가 깊은 땅 구덩이에 비밀을 털어놓고 흙으로 덮지만 그 자리에서 자라난 갈대가 바람에 흔들리면서 비밀이 폭로된다는 단순한 이야기로 등장인물은 왕과 이발사 뿐이다. 동서고금을 통해 전해 내려져 오는 이 민담은 우리나라에서도 경문왕 설화와 민담으로 전해져 오고, 초등학교 교과서에서도 이야기되고 있다. 어떤 것이 의식화되면 자동적으로 기계적인 것이 되는 경향으로 인해 진부해지기 때문에 경직되기 마련이다. 우리의 의식적인 삶이 경직되는 것을 피하고자 할 때 무의식에 있는 정신적 사건들의 흐름과 접촉을 통한 지속적인 갱신의 필요성이 생기는데, 집단적 의식의 내용들 중 가장 중심적 상징인 왕은 이러한 갱신의 필요성에 훨씬 따르게 마련이다. 심리학적으로 보자면 왕의 '당나귀 귀'는 삶의 흐름에서 잃어버린 근원적 감정과의 비합리적 접촉을 가능하게 해준다. 이발사는 영적 변환과 관련된 상징이며, 바람에 흔들리는 갈대는 비밀스러운 지식을 드러내는 신과 관련된 상징으로 왕이 '당나귀 귀'로 만물의 소리를 듣고 변환되어 하나이자 전체가 되어야 하는 것은 신의 뜻이었던 것이다. 한 개체의 정신적 총체이며 역설적으로 또한 전체 집단적 무의식의 조절 중심을 나타내는 자기는 합리적이고 물질적인 시대를 사는 우리들에게 인간 의식이 발달함에 따라 너무 멀리와 버려 잃어버린 인간의 근원적 층과 하나가 되어 변환될 것을 촉구하는 것 같다.

• Journal of Nutrition and Health
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• 제47권2호
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• pp.145-156
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• 2014

본 연구에서는 영양 식생활 교육자료에 대한 인증 시스템을 개발하기 위하여 2011년 4월부터 10월에 걸쳐 연구를 진행하였다. 문헌고찰, 인터뷰, 자문회의 및 전문가 회의, 설문조사, 공청회 개최 등의 체계적인 연구 절차를 통해 타당성, 신뢰성, 적용가능성을 갖춘 인증 시스템을 개발하고자 하였다. 인증 시스템 개발을 위하여 보건복지부의 우수건강도서, 환경부의 우수환경도서, 교육과학기술부의 우수과학도서, 문화체육관광부의 우수학술도서 및 우수교양도서, 농림수산식품부의 농업교육프로그램, 대한의학회의 건강정보심의인증, 시각장애인연합회의 사용자웹접근성인증, 한국정보화진흥원의 웹접근성품질마크, 문화체육관광부의 데이터베이스품질인증 제도를 분석 참고하였다. 본 연구에서 개발된 영양 식생활 교육자료에 대한 인증 시스템은 제 3자에 의한 인증 시스템으로 운영되며, 이를 위해 인증 운영기관에 인증위원회가 구성되어 인증 전반에 대한 업무를 관장한다. 인증 심사 절차는 신청 및 접수, 자료 정리 및 분류, 1차 심사 (서면평가), 2차 심사 (전체회의), 결과통보의 순으로 진행한다. 인증 심사위원은 3인으로 구성하며, 총 인증 심사기간은 2개월로 하고, 상반기와 하반기로 년 2회 접수를 실시한다. 인증 심사 결과는 적합 또는 부적합으로 평가하며, 최종 인증을 받은 교육자료는 인증서 및 인증마크를 발급받고, 홈페이지, 보도자료 등을 통한 홍보 추진, 공동주관기관을 통한 판촉 및 홍보를 지원하도록 한다. 인증 유효기간은 웹사이트의 경우에만 2년으로 하며, 갱신심사로 기간을 연장할 수 있다. 이상에서 개발된 영양 식생활 교육자료에 대한 인증 제도는 정보에 대한 신뢰성을 높여 교육과 학습에 대한 만족도를 높여줄 것으로 기대된다.