Kim, Sora;Min, Byung-Il;Park, Kihyun;Yang, Byung-Mo;Suh, Kyung-Suk
Journal of Radiation Protection and Research
/
v.41
no.4
/
pp.424-435
/
2016
Background: The International Commission on Radiological Protection (ICRP) recommendations and the Federal Guidance Report (FGR) published by the U.S. Environmental Protection Agency (EPA) have been widely applied worldwide in the fields of radiation protection and dose assessment. The dose conversion coefficients of the ICRP and FGR are widely used for assessing exposure doses. However, before the coefficients are used, the user must thoroughly understand the derivation process of the coefficients to ensure that they are used appropriately in the evaluation. Materials and Methods: The ICRP provides recommendations to regulatory and advisory agencies, mainly in the form of guidance on the fundamental principles on which appropriate radiological protection can be based. The FGR provides federal and state agencies with technical information to assist their implementation of radiation protection programs for the U.S. population. The system of radiation dose assessment and dose conversion coefficients in the ICRP and FGR is reviewed in this study. Results and Discussion: A thorough understanding of their background is essential for the proper use of dose conversion coefficients. The FGR dose assessment system was strongly influenced by the ICRP and the U.S. National Council on Radiation Protection and Measurements (NCRP), and is hence consistent with those recommendations. Moreover, the ICRP and FGR both used the scientific data reported by Biological Effects of Ionizing Radiation (BEIR) and United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) as their primary source of information. The difference between the ICRP and FGR lies in the fact that the ICRP utilized information regarding a population of diverse races, whereas the FGR utilized data on the American population, as its goal was to provide guidelines for radiological protection in the US. Conclusion: The contents of this study are expected to be utilized as basic research material in the areas of radiation protection and dose assessment.
Lee, Jin Wuk;Park, Seonyeong;Jang, Seok-Won;Lee, Sanggyu;Moon, Sanga;Kim, Hyunji;Kim, Pilje;Yu, Seung Do;Seong, Chang Ho
Journal of Environmental Health Sciences
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v.45
no.5
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pp.457-464
/
2019
Objectives: Quantitative structure-activity relationship (QSAR) is one of the effective alternatives to animal testing, but its credibility in terms of toxicity prediction has been questionable. Thus, this work aims to evaluate its predictive capacity and find ways of improving its credibility. Methods: Using $TOPKAT^{(R)}$, OECD toolbox, and $Derek^{(R)}$, all of which have been applied world-wide in the research, industrial, and regulatory fields, an analysis of prediction credibility markers including accuracy (A), sensitivity (S), specificity (SP), false negative (FN), and false positive (FP) was conducted. Results: The multi-application of QSARs elevated the precision credibility relative to individual applications of QSARs. Moreover, we found that the type of chemical structure affects the credibility of markers significantly. Conclusions: The credibility of individual QSAR is insufficient for both the prediction of chemical toxicity and regulation of hazardous chemicals. Thus, to increase the credibility, multi-QSAR application, and compensation of the prediction deviation by chemical structure are required.
Yasser, Norhan;Salem, Reda;Alkhazindar, Maha;Abdelhamid, Ismail A.;Ghozlan, Said A.S.;Elmenofy, Wael
Microbiology and Biotechnology Letters
/
v.49
no.3
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pp.305-315
/
2021
The cotton leafworm, Spodoptera littoralis, is a major pest in Egypt and many countries worldwide, and causes heavy economic losses. As a result, management measures to control the spread of the worm are required. S. littoralis nucleopolyhedrovirus (SpliNPV) is one of the most promising bioagents for the efficient control of insect pests. In this study, a chitinase gene (chitA) of a 1.8 kb DNA fragment was cloned and fully characterized from SpliNPV-EG1, an Egyptian isolate. A sequence of 601 amino acids was deduced when the gene was completely sequenced with a predicted molecular mass of 67 kDa for the preprotein. Transcriptional analyses using reverse transcription polymerase chain reaction (RT-PCR) revealed that chitA transcripts were detected first at 12 h post infection (hpi) and remained detectable until 168 hpi, suggesting their transcriptional regulation from a putative late promoter motif. In addition, quantitative analysis using quantitative RT-PCR showed a steady increase of 7.86-fold at 12 hpi in chitA transcription levels, which increased up to 71.4-fold at 120 hpi. An approximately 50 kDa protein fragment with chitinolytic activity was purified from ChitA-induced bacterial culture and detected by western blotting with an anti-recombinant SpliNPV chitinase antibody. Moreover, purification of the expressed ChitA recombinant protein showed in vitro growth inhibition of two different fungi species, Fusarium solani and F. oxysporum, confirming that the enzyme assembly and activity was correct. The results supported the potential role and application of the SpliNPV-ChitA protein as a synergistic agent in agricultural fungal and pest control programs.
Journal of the Korean Society of Environmental Restoration Technology
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v.22
no.5
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pp.13-25
/
2019
The Baekdudaegan protected area is a regulatory-oriented policy that does not consider the residents, and has been affected by the shrinking of local economy and the reduction of community activities. In order to minimize the damages, Baekdudaegan resident support programs has been implemented but various problems have been pointed out failing to lead to local revitalization. In addition, the zoning districts consists only of the core district and buffer district, which makes it more difficult to improve the lives and satisfy the needs of residents due to the stricter regulations. This study suggests the revitalization of Baekdu-daegan protected area by reforming the zoning system of Baekdu-daegan protected area. Considering related plans and systems, legal validity, residents' repulsion, area, etc., four reorganization plans were drawn according to each strength and weakness. Principles, additional permissible activities, example of amendment to 'Baekdudaegan Protection Act' according to each plan were also presented. The results of this study can contribute to the improvement of income and welfare of the residents in Baekdudaegan protected area. However, further research is needed because it is a limitation that the specific scope of the proposed plans could not be set.
This study examines the regulatory issues and introduction problems of TV-betting data broadcasts in Korea by in-depth interview with a panel group. TV-betting data broadcast services of card games and horse racing games are widely in use in Europe and other parts of the world. In order to carry out the study, a demo program of TV-betting data broadcast in the OCAP(OpenCableTM Application Platform Specification) system environment, which is the data broadcasting standard for digital cable broadcasts in Korea was exposed to the panel group and then they were interviewed after watching and using the program. The results could be summarized as below. First of all, while TV-betting data broadcasts have many elements of entertainment, the respondents thought that it would be difficult to introduce TV-betting in data broadcasts as in overseas countries largely due to social factors. In addition, in order to introduce TV-betting data broadcasts, they suggested that excessive speculativeness must be suppressed through a series of regulatory system devices, such as by guaranteeing credibility of the media based on safe security systems for transactions, scheduling programs with effective time constraints to prevent the games from running too frequently, limiting the betting values, and by prohibiting access to games through set-top boxes of other data broadcast subscribers. The general consensus was that TV-betting could be considered for gradual introduction within the governmental laws and regulations that would minimize its ill effects. Therefore, the government should formulate long-term regulations and policies for data broadcasts. Once the groundwork is laid for safe introduction of TV-betting on data broadcasts within the boundary of laws and regulations, interactive TV games are expected to be introduced in Korea not only for added functionality of entertainment but also for far-ranging development of data broadcast and new media industries.
A solution on pesticide minor use is being requested world widely on behalf of growers and for the appropriate measure for pesticide regulation. Presently, definition on "minor use" is different by country. And furthermore registration for pesticide use and the regulation approach are dependent on whether the crop is minor or major. For these reasons, management for pesticide minor use are more complicated and aggravated. This paper aimed to provide information on definition of minor use, minor use programs and regulatory incentives for minor use registration, with the purpose of supporting in developing a possible solution on minor use situation in Korea. In conclusion, two suggestions were made based on the worldwide information on pesticide minor use. First, a prudent consideration should be taken in defining minor use legally in Korea, which should include all situations regarded with minor use of pesticide, besides the use of pesticide on the crops cultivated in small area. Secondly, it is proposed to strengthen the present program, the "Ex Officio Registration" (implemented since 1998 in Korea, lead by the Rural Development Administration) by introducing a cooperative program like IR-4 Project of the USA, which is well known as an effective program for minor use solution as mentioned in the OECD guidance.
The purpose of this paper is to explore the relationship between industrial regulations and the R&D activities of firms by analysing the case of manufacturing enterprises in Korea. The sample is gathered from the 2012 Korean Innovation Survey data of Korean Institute of Science & Technology Evaluation and Planning and merged with Korean Regulation Index data of Korean Institute of Public Administration. The Ordinary Least Square (OLS) as well as 2 Stage Least Square (2SLS) regression results show that the impact of the level of the manufacturing field's regulation on firms' R&D activities or inputs may be both positive and negative, depending on the size of the firms. The analysis results suggest that regulatory policy makers need to formulate and implement R&D programs that consider the different effects of industrial regulations on large enterprises or Small and Medium sized Enterprises (SMEs).
Since 1960's along with industrialization and urbanization, economic growth has been . achieved, however, at the same time, environmental condition has been seriously deteriorated. . Currently, volume of wastewater has been increasing at annual rate of 7% in sewage and 20% in industrial wastewater. However, the nation's sewage treatment serves only 33% of the municipal wastewater as of 1991. Major portion of air pollutants comes from combustion of oil and coal which comprise 81% of total energy use and emission gases from motor vehicles increasing at an accelerated rate. It is known that Korea generates the highest amount of waste per capta. Nevertheless, it is not sufficient to reduce the volume of waste by means of resources recovery and recycling. Recognizing the importance of global environmental problems such as ozone layer depletion, global warming and acid rain, international society has been making various efforts since the 1972 Stockholm conference. In particular, it is expected that the Rio conference which has adopted the Rio declaration and Agenda 21 will form a crucial turning point of the emerging new world order after the Cold War confrontation. To cope with such issues as domestic pollution and global environmental problems, the fundamental national policy aims at harmonizing "environmental protection and sustainable development". The Ministry of Environment has recently set up a mid-term comprehensive plan which includes annual targets for environmental protection. According to the government plan, gradual improvement of various environmental conditions and specific measures to achieve them is planned in time frame. Additional sewage treatment plants will be constructed in urban areas with the target to treat 65% of the nation's municipal sewage by 1996. Supply of clean fuels such as LNG will also be expanded starting from large cities as a cleaner substitute energy for coal and oil. In parallel with expansion of LNG, emphasis will be placed on installation of stack monitoring system. Due to the relatively limited land, government's basic policy for solid waste treatment is to develop large scale landfill facilities rather than small sized ones. Thirty three regional areas have been designated for the purpose of waste management. For each of these regions, big scale landfill site is going to be developed. To increase the rate of waste recycling the government is planning to reinforce separate collection system and to provide industries with economic incentives. As a part of meeting the changing situation on global environmental problems after UNCED, and accommodation regulatory measures stipulated in the global environmental conventions and protocols, national policy will try to alter industrial and economic structure so as to mitigate the increasing trends of energy consumption, by encouraging energy conservation and efficiency. In this regard, more attention will be given to the policy on the development of the cleaner technology. Ultimately, these policies and programs will contribute greatly to improving the current state of national public health.
When assessing environmental or other regulatory programs, economists and other policy analysts have traditionally used the approach that consists of comparing the benefits from regulation with the costs that must be borne to capture these benefits. The vast majority of economic analysis of regulation was based upon the assumption that regulations increase production costs. Porter had disputed this seemingly straightforward claim. In his view, economists had failed to incorporate the capacity of stringent regulations to induce innovation into their analysis. However, at the same time, the hypothesis had been criticized by economists. This study analyzed the determinants of innovation performances as well as activities of small and medium manufacturers, based on a recently held survey among mainly manufacturing SMEs in Korea. In particular, this study took the level of innovation activities, the strength of environmental regulations, and moreover the impediment that the company went through as factors. In addition, the characteristics of innovative SMEs were compared with the other counterparts. The empirical analysis revealed that the level of environmental awareness, existence of innovative activities, characteristics of firms, and moreover the innovation types are the most important determinants of SMEs’ innovation performance both in technology as well as in economic perspective.
Nuclear power plants (NPPs) in Korea are required to be maintained using a defense in-depth approach to prevent leakage of radioactive substances outside the plant and allow safe shutdown in the event of a fire. Periodic testing must be conducted to ensure that the fire protection facilities perform as required by the laws for various nuclear reactor types. In June 2017, for the first time in Korea, a nuclear plant, Kori Unit 1, was permanently shut down. It was prepared for decommissioning in accordance with the fire protection regulations imposed by the regulatory body. However, a standard protocol is necessary for systematically establishing the fire protection program for decommissioning of NPPs in the future. Therefore, the nuclear legal systems of countries with many operating nuclear power plants, such as the United States, Japan, Canada, and various European countries, were reviewed and guidelines for establishing a fire protection program for decommissioning NPPs was suggested; the fire protection requirements stated by Reg Guide 1.191 (Decommissioning fire protection program for NPPs during decommissioning and permanent shutdown) were used as a model. Suggestions for establishing legal regulations to optimize fire protection programs and secure basic technology for decommissioning NPPs were also made.
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