• 생명과학회지
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• 제29권2호
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• pp.256-264
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• 2019

Lymphotoxin ${\beta}$ receptor ($LT{\beta}R$)는 TNF 계열로 림프조직의 미세구조와 기관형성에 중요한 역할을 한다. MLCK와 ROCK는 세포의 stress fiber 형성조절에 관여하는 주요 신호전달자이다. Fibroblastic reticular cell (FRC)에서 $LT{\beta}R$ 자극을 통한 이런 신호전달자들의 관련성을 알아보기 위해 ML-7 (MLCK 저해제)이 사용되었다. ML7 처리된 FRC에서 SF가 완전히 파괴되었고 anti-$LT{\beta}R$ antibody 처리 세포와 유사하게 ML7 처리 FRC에서 응축된 세포형태를 관찰 할 수 있었다. Y27632로 ROCK를 저해 했을 때 FRC의 액틴 세포골격과 세포형태 변화가 유도 되었다. FRC에서 p-MLC가 액틴과 함께 SF 구성성분을 이루었다. FRC세포 추출물로 Rho-guanosine diphosphate (GDP)/guanosine triphosphate (GTP) 교환활성을 확인했다. Agonistic anti-$LT{\beta}R$ antibody로 $LT{\beta}R$을 자극 했을 때 Rho-GDP/GTP 교환활성이 크게 감소했다. MLCK 저해처럼 $LT{\beta}R$ 자극은 MLC의 인산화를 감소시켰다. Agonistic anti-$LT{\beta}R$ antibody-treated FRC에서 세포골격 구성요소인 세포막과 세포골격 링커 역할을 하는 p-ezrin의 인산화는 감소 되었고 b- actin, 그리고 tubulin 발현도 줄었다. 이런 결과는 FRC의 $LT{\beta}R$ 신호전달을 통한 SF 조절에는 MLCK와 ROCK가 관여하고 있다는 것을 알 수 있었다.

• 대한조선학회논문집
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• 제56권1호
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• pp.34-46
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• 2019

This paper provides the numerical results for the self-propulsion performance in waves of a car ferry vessel with damage in one of its twin-screw propulsion systems without flooding the engine room. The numerical simulations were carried out according to the Safe Return to Port (SRtP) regulation made by the Lloyd's register, where the regulation requires that damaged passenger ships should have an ability to return to port with a speed of 6 knots in a Beaufort 8 sea condition. For the validation of the present numerical analysis study, the resistance performance and the self-propulsion performance of the car ferry in intact and damaged conditions in calm water were calculated, which showed a satisfactory agreement with the model test results of Korea Research Institute of Ship and Ocean engineering (KRISO). Finally, the numerical simulation of self-propulsion performance in waves of the damaged car ferry ship was carried out for a normal sea state and for a Beaufort 8 sea state, respectively. The estimated average Brake Horse Power (BHP) for keeping the damaged car ferry ship advancing at a speed of 6 knots in a Beaufort 8 sea state reached about 47% of BHP at MCR condition or about 56% of BHP at NCR condition of the engine determined at the design state. In conclusion, it can be noted that the engine power of the damaged car ferry ship in single propulsion condition is sufficient to satisfy the SRtP requirement.

• 한국건설순환자원학회논문집
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• 제4권4호
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• pp.379-387
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• 2016

본 연구에서는 지하부위의 누수 예방 기술 정책 수립을 위한 방수 성능 분석 연구에 대하여 설문조사를 실시하고 이를 분석하였다. 설문 분석 결과, 현재 공동주택 지하공간에 대한 누수는 심각하며, 응답자 대부분도 이를 심각하게 인식하고 있다. 환경을 고려하지 않은 누수설계 및 누수예방 설계의 부재, 환경에 적합하지 않은 시공 시스템의 활용이 누수문제의 주요 원인이라 판단되었으며, 이를 개선하기 위하여 지하부위 외방수공법의 도입을 의무화하고, 설계시 공동주택 지하부위에 적용할 수 있는 표준 방수 기술 및 공법을 수립해야 될 것이며, 지하 시공환경을 고려한 방수 시공방법의 개발의 필요성이 강조되었다. 따라서 상기의 상황을 미루어 볼 때 법-제도에 의해 명시된 방수설계, 재료 및 공법, 유지관리 등을 방수시공의 전반적인 상황 컨트롤할 수 있는 가이드라인의 제시는 필수요소로 부각되었다.

• KIEAE Journal
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• 제10권5호
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• pp.109-114
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• 2010

There are many business in complex building, and recently noise claims have increased in those buildings. It is one of the most desirable methods reducing the noise level to establish the noise criteria considering the admittable noise level between the source and receiving room, which are to be derived from the subjective response in the real conditions. Because the degree of annoyance and loudness for the intruding noises in complex building could be changed with background noise level, it is suggested to be researched the relationship between the noise levels and subjective response. In this study, the subjective response for three different background levels in receiving business or rooms were investigated for the typical eight business noise source including aerobic music. The results can be summarized as follows. In conditions of low background noise level(40 dB(A)), there is a tendency of intentionally attention situation (listening) in a subjective test. The other hand in conditions of relatively high background noise level(50 dB(A)), there is a unconscious situation (heraing). As the degree of moderately heard or annoyed in SD rating scale means that the noise is easily recognized in neighboring shops, usually the limit of noise criteria were decided on this rating point, so it will be reasonable to be adopted the criteria rating scale as slight heard or annoyed degree (SD criteria 3).

• 대한건축학회논문집:계획계
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• 제33권12호
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• pp.105-112
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• 2017

Through various media, damage of both smoking and second-hand smoking has been recognized, and brought global scale of interest in antismoking. In Korea, government has tightened regulations of smoking in non-smoking zone since December, 1980, and after National Health Promotion Act in 1995, non-smoking zone has been gradually expanded. On the other hand, there were law suits to find those regulation towards smokers are either unconstitutional or not for 4 times. In this current state, people need smoking area to prevent second-hand smoking and to consider smokers in multi-unit dwelling. Main purpose of this research is to plan smoking spaces based on various typology of multi-dwelling plan for protection of both smokers and non-smokers' right. The research group collected and analyzed the smoking behaviors in various multi-unit dwelling types such as flat type, tower type, hybrid type and others. Based on those data, the group found three phenomena. First, there are internal regulations in multi-unit dwelling to make non-smoking zone based on National Health Promotion Act and resident representative meeting decision. Second, main smoking activities are occurring at major traffic line and entrances. Third, smoking inside of multi-unit dwelling complex causes second-hand smoking to residents live in $1^{st}$ floor and when they enter. Therefore, one can achieve both smokers' and non-smokers' protection of right by creating a designated smoking space near main entrances of multi-unit dwelling complex to consider smokers' and prevents second-hand smoking by using shaft space, which is in core space, to ventilate tobacco smoke through roof.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제20권4호
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• pp.67-80
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• 2014

Purpose : Long-term Care Insurance sets up facility standard and installation standard of aged care facilities and decides the presence of minimum number of rooms and its size in care facilities by using systematic instruments. Therefore, most aged care facilities had renovation in expansion and reconstruction following the revised regulations and even facility space structure and space composition are continuously improving. The study is to determine the purpose and trend by comparing before and after space composition of facilities which followed the implementation of Long-term Care Insurance and also to suggest hierarchical space composition suitable for aged care facilities through derived problems and to provide basic materials to plan the most appropriate facility for the aged. Methods : J-graph based on Space Syntax Theory will be schematized through in-site facility survey and before and after facility floor plan. Space composition trend will be analyzed by comparing indexes through S3 program. Results : As a result of 5 cases analysis, the following results were found; the average of whole space depth is increasing due to the Extension, the number of volunteers is decreasing and rooms for geriatric care helpers are being created due to the geriatric care helper introduction duty. Also, there are solariums being created to improve the health of the aged and dispensaries are being placed on every floor with the increase of documentary work for geriatric care helpers. With the policy implementation, care facility space composition and structure are changing with facility standard and it was analyzed that facilities were mostly put under the control of limited number of people in care room and total ground area per person. It was also found that there is increase in care space integration through before and after comparison of whole integration value. This is considered as the important result not only in facility standard satisfaction, but also in care support of geriatric care helpers and the aged, its main users. Implication : In order for elderly care facilities to have quality improvement and to develop as suitable facilities for characteristics of the aged, independent environmental facility standard preparation of elderly care facilities is needed through mutual cooperation of construction fields with regulation and policy related researches.

• 전자공학회논문지
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• 제50권1호
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• pp.148-156
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• 2013

본 논문에서는 디지털 제어부를 공유하며, 회로 동작시간의 분배 방식을 통해 다중 출력을 지원하는 SMPS를 제안한다. 제안된 회로는 Pseudo Relaxation Oscillating 기법의 DPWM 발생기를 사용한다. 제안된 SMPS는 회로의 동작시간 분배 방식을 사용하여 기존의 DPWM 발생기에서 문제가 되는 큰 면적의 디지털 로직 컨트롤러를 공유하는 형태이기 때문에 칩 면적과 효율 측면에서 큰 이점을 가지지만, 각 DPWM 발생기의 실시간 제어가 어려우며 불안정한 출력 전압을 공급할 수 있다는 단점을 가진다. 이를 해결하기 위해 본 논문에서는 동작시간 분배 방식으로 인해 동작클록이 인가되지 않은 DPWM 발생기들의 출력전압을 실시간으로 피드백 받아 안정된 출력 전압을 공급할 수 있는 실시간 전류 보정 기법을 제안한다. 제안된 SMPS를 100MHz의 내부 제어 동작 주파수와 10MHz 스위칭 주파수로 동작시킬 시, 소모되는 내부 코어 회로의 최대 전류는 4.9mA이며, 출력 버퍼를 포함한 전체 시스템의 전력 소모는 30mA이다. 또한 800mA, 100KHz의 load current regulation 조건으로 시뮬레이션 시, 3.3V 출력전압에 대한 최대 리플 전압은 11mV, Over/Undershoot voltage는 각각 10mV, 19.6mV 이다. 코어 회로의 크기는 $700{\mu}m{\times}800{\mu}m$의 작은 면적으로 구현가능하다. 제안된 회로는 Dong-bu Hitek BCD $0.35{\mu}m$ 공정을 이용한 시뮬레이션을 통해 검증되었다.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제9권12호
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• pp.387-402
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• 2020

기존의 자동차 개발은 주로 정확성(Correctness) 및 안전성(Safety) 확보에 초점을 맞추어 왔으며, 이에 반해 보안성(Security)은 비교적 소홀하게 다루어져 왔다. 하지만 최근 자동차의 인터넷 연결성이 높아짐에 따라 자동차 해킹 사례가 증가하면서, 유엔유럽경제위원회(United Nations Economic Commission for Europe, UNECE)와 같은 국제기관은 자동차 개발에 대한 보안성을 확보하기 위해 사이버보안 규제를 준비하고 있다. 다른 IT 제품과 마찬가지로 자동차 사이버보안 규제에서 또한 개발 초기부터 보안성을 고려하는 "보안 내재화(Security by Design)"의 개념을 강조한다. 특히 자동차 개발은 생명주기가 길고 공급망이 복잡하기 때문에 개발 이후에 아키텍처를 변경하는 것이 매우 어려우므로, 자동차 개발에 있어 보안 내재화는 기존 IT 제품에 비해 훨씬 더 중요시된다. 그러나 문제는 아직 자동차 개발 과정에 보안을 내재화하는 구체적인 방법론이 제시되지 못하고 있다는 것이다. 이에 본 논문에서는 자동차 보안 내재화를 위한 구체적인 방법론을 제안한다. 본 논문에서 제안된 방법론을 통해 자동차 제조사는 자동차 개발 과정에 있어 기능 안전성과 보안성의 측면을 동시에 고려할 수 있으며, 다가오는 UNECE 자동차 사이버보안 규제에 대한 인증에도 대응할 수 있을 것이다.

• KIEAE Journal
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• 제1권2호
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• pp.63-70
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• 2001

With environmental problems and pollutions accumulated by continuous towns or cities developments events, it is becoming necessary to develop in consideration of environmental effects. This consensus leads to prepare a plan system and instrument for ecological city development, which can be a series of planning indicators. To develope a series of process for environmental friendly development, this study has three main goals as follows; development of policies and programs for environmental friendly development, suggestion of environmental friendly urban design models and standards, development of planning indicators and design guidelines Korean land use plan is operated by both zoning system and detailed plan system. But the available kinds of zoning type are too limited to apply to various and vernacular places. In addition to, the detailed plan is understood to be another regulation which constricts the freedom of building right. In this study, Plan System of Environmentally Friendly Space was studied for domestic affairs In German, Plan System of Environmentally Friendly Space is the field have been progressed before. so In this study, example of German was researched intensively, and Plan System of Environmentally Friendly Space was developed, applicable for the real state in domestic. This study was focused on methodology of landscape planning and planning for afforestation. Landscape planning is performed on condition detail investigation of existent state of nature and local characteristic, and Investigation of Planning for afforestation is more detailed than that of Landscape planning. In the basis of methodology of landscape planning and planning for afforestation, Plan for Environmentally Friendly Urban Habitation Model was developed. Plan for Environmentally Friendly Urban Habitation Model was applicable for state of land use planning. Site was selected Chuk-chun in city yang-in, taking the circumstances into consideration. So landscape planning correspond to land use planning was made out. Adjustment of Land use planning and Landscape planning was very important. Undergoing this process, Plan for Environmentally Friendly Urban Habitation Model was performed.

• 한국주거학회논문집
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• 제24권1호
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• pp.33-40
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• 2013

This study has examined layout of communal outdoor space and welfare facilities in the nation's very first senior apartment complex in Segok-dong, Gangnam-gu that has been developed by Seoul City. In order for this space to play a role as a center of communication: 1) A center space of community should be created at the point of intersection of main moving lines of pedestrians. 2) Hierarchical area should be set up between main moving lines of walking and communal outdoor space. 3) It should be designed in a way to reflect demands of seniors and be accommodated their activities and behaviors. 4) It should be functionally connected to local infrastructure facilities so that it can promote social exchanges among seniors. Points to be considered in welfare facilities: 1) They should be placed at the center of the complex to provide convenience to all seniors. 2) Area of senior citizen center should be subject to flexible legal regulation in light of the unique characteristics of the Complex. 3) in case that welfare facilities are installed in the same space, intermediate space is required to alleviate collision between private space and public space. 4) Senior assistance facilities should put more emphasis on running programs that make good use of the space than on securing the space itself.