• 대한방사성의약품학회지
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• 제6권2호
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• pp.171-176
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• 2020

Covalent organic frameworks (COFs) are porous crystalline polymers in which organic units are linked by covalent bonds and have a regular arrangement at the atomic level. Recently, the COFs have been much attention in bio-medical area such as bio-imaging, drug delivery, and therapeutics. These 2D nanoparticles are proving their value in nanomedicine due to their large surface area, functionalization through functional groups exposed on the surface, chemical stability due to covalent bonding, and high biocompatibility. The high ω-electron density and crystallinity of COFs makes it a promising candidate for bioimaging probes, and its porosity and large surface area make it possible to be utilized as a drug delivery vehicle. However, the low dispersibility in water, the cytotoxicity problems of COFs are still challenged to be solved in the future. In this regard, several efforts that increase the degree of dispersion through functionalization on the surface of COFs for the application to the biomedical field have been reported. In this review, we would like to describe the advantages and limitations of COFs for bio-imaging and anti-cancer treatment.

• 대한두경부종양학회지
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• 제39권2호
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• pp.41-44
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• 2023

Follicular dendritic cell sarcoma (FDCS) is rare lymphoid sarcoma occurs anywhere in body, mostly in lymph nodes. Sixty-two-year-old man presented left submandibular gland region mass for 5 months. Mass excision with submandibular gland resection was performed. Histopathology showed proliferation of spindle and ovoid cells with storiform arrangement which were positive for CD21, CD23, Vimentin, Ki-67, suggested FDCS in submandibular gland region lymph node. Tumor size was 3cm with no involvement of resection margin, nor cellular atypia and necrosis, so regular follow up was performed. After 4 years, new enhancing mass in left submandibular area was found. Wide excision of mass with neck dissection on left level I-III was performed. Histopathology confirmed recurrence of FDCS. The patient underwent radiation therapy from left mandible to hyoid area. After 2 years, new nodule was found in left lung upper lobe, and wedge resection confirmed metastasis of FDCS. The patient is on adjuvant chemotherapy.

• 비교교육연구
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• 제28권3호
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• pp.23-47
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• 2018

본 연구는 한국과 러시아 상호 간의 학위인정제도에 대한 이해를 높이고 관련 쟁점에 대한 논의를 통하여 향후 학위인정협정 체결 시에 도움을 줄 수 있는 방안을 마련하고자 수행되었다. 이를 위하여 한국과 러시아에서 양국의 학위인정 방식을 살펴보고 양국의 국가 간 학위 상호인정 현황을 분석하였으며, 마지막으로 한-러 학위인정 협정 논의 과정에서 나타나는 쟁점과 이에 대한 개선방안을 제시하였다. 학위인정 협약 논의에 있어서 쟁점은 첫째, 협약의 수준(명칭)을 정부간 협정(agreement)으로 할 것인가 기관 간 약정(arrangement)을 할 것인가, 둘째, 협정문에서 제시되고 있는 자격이 구체적으로 의미하는 바와 그 범위는 무엇인가, 셋째, 상호 학위인정 적용의 보편성 문제와 관련하여, 협정 체결시 동 협정이 모든 러시아의 연방주체들에게도 보편적으로 적용될 수 있는가 하는 것이었다. 본 연구에서는 포괄적이고 일반적 수준에서 학위 상호인정협정을 체결하고, 동 협정에서 자격은 학문적 자격으로 한정하도록 하며, 상호협정 체결시의 보편성을 명문화해야 한다는 방안을 제시하였다. 본 연구 결과를 바탕으로 한-러 학위상호인정협정 체결과 실행 과정의 체계화를 마련하는 것과 실제 협정체결과 체결 후의 후속조치를 위해서는 양국 전문가들과 정부 담당자들 간의 정기적 지속적 논의의 필요성을 제안하였다.

• 대한화장품학회지
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• 제30권2호
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• pp.279-294
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• 2004

본 연구는 화장품에서 사용되는 액정기술에 대하여 기술하였다. 액정이란 고체와 액체의 중간 상태에 존재하는 다양한 형태의 구조를 액정이라 한다. 계면활성제의 높은 농도에서 여러 가지 액정 상이 형성된다. 결정과 같이 분자배열이 규칙적이지는 않지만, 액체 상보다는 비교적 규칙적인 상태를 액정 또는 메조페이스(meso-phase)라고도 말한다. 일반적으로 화장품에서의 액정기술의 종류, 새로운 액정기술에 대하여 설명하였으며, 액정을 만드는 방법에 대하여도 자세히 기술하였다. 특히, 액정을 형성하기 위한 특별한 유화제의 종류에 대하여도 소개하였다 액정을 형성하기 위한 대표적인 원료는 수소첨가 레시친, 세라마이드, 디팔미토일하이드록시프롤린, DEA-세틸포스페이트, 제미니형 계면활성제가 있다. 액정의 형성을 관찰하기 위하여 편광 현미경을 사용하였으며, 가장 잘 나타나는 범위는 400배, 600배, 1,000배에서 잘 나타났다. 또한 액정이 가장 잘 만들어지는 droplet 입자크기는 1-10$\mu\textrm{m}$이었다. 임상 결과로서, 비타민 B$_{5}$의 액정에 대하여 피부 보습효과를 측정한 결과 일반 에멀젼보다 우수한 결과(20% 이상)를 보였다(ANOMA t-test, p '||'&'||'lt; 0.05).

• 대한지역사회영양학회지
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• 제19권2호
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• pp.142-162
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• 2014

Objectives: To evaluate the critical environmental factors on healthy-aging of Korean people, we investigated the significant factors influencing health status of septuagenarians living in rural area of Jeonla province, known to be one of the representative longevity regions in Korea. Methods: We divided subjects into healthy group (36M/25F) or poor-health group (26M/73F) based on self-reported health status, body mass index, a number of prescription, and blood test data. General characteristics, physical measurements, lifestyle, dietary behavior and nutrient intake, physical health and mental health data were statistically compared between the two groups. Results: Average age was not different between healthy group and poor-health group in men and women, respectively. In men, significantly favorable factors to health were observed to be higher education, regular exercise, higher grip strength and walking function, body mass index (${\geq}18.5kg/m^2$), moderate frequency of drinking and eating-out, non-smoking, normal red blood cell (RBC) count, higher serum dehydroepiandrosterone-sulfate (DHEAS) level, good digestive function and appetite, normal hearing function, regular meals, adequate vegetable and fruit intake, diverse food intake, adequate energy and nutrients (protein, vitamin $B_1$, $B_6$, C and E, folate, niacin, P, Zn and K) intake, higher mini-nutrient status assessment (MNA) score and low level of depression. On the other hand, in women, those were literacy, living arrangement, moderate frequency of drinking, healthy teeth, higher grip strength and walking function, bone mineral density, normal RBC and white blood cell (WBC) count, higher DHEAS concentration, higher MNA score, normal cognition and memory function, having snack and adequate fruit intake. Conclusions: These results could be useful to plan effective strategies to increase health-life expectancy of Korean old people living in rural areas.

• 대한물리치료과학회지
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• 제3권2호
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• pp.1021-1036
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• 1996

The purpose of this study are ( i ) to examine operating situation of physical therapy department and job satisfaction of physical therapists in health centers, (ii) to analyze utilization patterns and patient satisfaction of physical therapy services among health center visitors, and finally, (iii) to suggest policy implications in facilitating improvement on physical therapy services of health centers. The materials are collected from 105 physical therapists among nationwide health centers and 203 patients of 5 health centers in Pusan, Korea. The survey is conducted from February 13 to March 30, 1996 with a structured self - administered questionnaire. Major results of the study are as follows. First, the result of regression analysis between job satisfaction and affecting factors identify following variables as the significant determinants; self-development(+), job itself(+), and co-worker support (+). Second, the current operating situation of physical therapy department shows such problem as; i )shortage and unstable job security of physical therapists, ii )absence of rehabilitation specialist, iii )lack of understanding on physical therapy of co-workers, iv)shortage of physical therapy equipment and facility, v)burdensome task of physical therapists, and vi) inappropriate purchase process of equipment. Third, patient satisfaction for physical therapy services are revealed relatively high. And the result of regression analysis between patient satisfaction and affecting factors identify following variables as the significant determinants; credibility of physical therapist(+), satisfaction for waiting time(+), cleanliness(+). Fourth, the patients appeal about physical therapy services such problem as; i) shortage of physical therapists, physical therapy equipment, and facility, ii) inconvenient administrative procedure for utilization physical therapy services. Fifth and last, recommendations for the improvement of physical therapy services of health centers are as follows; i )recruiting more physical therapists, ii )regular employment of physical therapists instead of daily use employment, iii )re-arrangement of facility for patient's convenience, iv )establishing reasonable purchasing system of equipment for physical therapy, v) reforming administrative procedure for patient focused care.

• 한국실내디자인학회논문집
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• 제20권6호
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• pp.262-271
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• 2011

The purpose of this study was to classify types of family visitors' behaviors more concretely, which could be useful in planning of exhibition spaces in a science museum, with given priority to their behaviors according to interaction between them, and to understand characteristics of the behaviors. With this view, the scope of this study was restricted to subjects, who were family visitors of Gwacheon National Science Museum, consisting of parents and their one elementary school child per family unit. For understanding their behaviors, itinerary tracking and observation method of behavior were conducted. Moreover, for understanding substantial types and characteristics of family visitors' behaviors, multivariate analysis was applied. Accordingly, the results of the study are as follows. First, as a result of factor analysis, two main factors were derived. In other words, they were 'Durability of viewing' as the first and 'Interactivity between family members' as the second, which were shown valid in classification of the types of their behaviors. Second, according to the factors derived, the types of their behaviors were classified into in-depth cooperative viewing, selective independent viewing, interest concentration child-led viewing and consideration parent-led viewing. They were shown valid in topological localization and classification, as a result of analysis of the main factors. Third, in view of common characteristics of the types, it is judged that active orientation prior to regular viewing could encourage visitors coming to the museum for the first time to feel more friendly to unfamiliar exhibition environments, during the initial seek time, and to reduce visual supersaturation. Fourth, it is judged that distributed arrangement of exhibits, which result in continuous standby, could avoid confused visitor circulation by the estimated time required for viewing.

• Journal of the Korean Wood Science and Technology
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• 제46권2호
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• pp.125-131
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• 2018

This study was conducted to understand and to compare the qualitative aspects of anatomical characteristics in compression wood (CW), lateral wood (LW), and opposite wood (OW) in a stem of Ginkgo biloba. The qualitative analysis was examined by optical microscopy and scanning electron microscopy. CW in Ginkgo biloba disks were dark brown in color, and the OW and LW were light brown in color. CW and OW showed abrupt transitions from earlywood to latewood, while LW showed a gradual transition. Cross sections of CW presented circular tracheids with angular outlines, many intercellular spaces, and varying sizes of lumens. Cross sections of LW and OW showed rectangular tracheids, fewer intercellular spaces, and varying sizes of lumens. In radial sections, CW showed an irregular arrangement of tracheids in earlywood, while LW and OW showed comparatively regular arrangements. Slit-like bordered pits on the tracheid cell wall, piceoid pits in the crossfield, and a few spiral checks were present in CW. LW and OW showed bordered pits with slightly oval-shaped apertures, as well as cuppresoid pits in the crossfields. Rays were primarily uniseriate, with few biseriate rays in the tangential sections of CW, LW, and OW. The tips of the tracheids were branched in CW but had a normal appearance in LW and OW.

• 한국의류산업학회지
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• 제20권5호
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• pp.592-599
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• 2018

The purpose of this study is to investigate consumer needs, image sensibility and preference of bedding fabric according to size and spacing of dot pattern. 18 kinds of dot pattern fabrics were designed with different diameters(6, 8, 10cm) and distances(4, 7, 10cm) in regular arrangement of diamond figure. The subjects were 162 male and female university students. The data were analyzed by SPSS 24.0. Fabrics were assessed subjectively using a 5-point scale 17 consumer needs and 33 sensory descriptors. The most consumer's needs for bedding fabric was shown to be functionality of bedding including hygiene, touch, warmth, ease of washing and management, air permeability, and hygroscopicity. The other parameters of consumer's needs were shown to be physical property and design parameter. The results of analysis of the dimension of image sensibility for fabrics with different size and spacing of dots are derived from six factors including joyfulness, coziness, uniqueness, charm, femininity, and complexity. As a result of analysis of preference with fabric kinds, there was a significant difference in preference with fabrics. The preferred fabrics were characterized by the pattern and the base fabric being striking three-dimensionally with 1/3 twill and 3/1 twill fabric. Sensory descriptors related to joyful image and unique image were analyzed as evaluation terms that can distinguish the preferences of fabrics. Correlation analysis showed the fabrics are preferred as the difference in luminance and reflectance between the base and pattern of the fabric become larger and the spacing of patterns become closer.

• 생명과학회지
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• 제16권2호
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• pp.225-230
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• 2006

생육온도가 느타리버섯 자실체의 생육 및 조직에 미치는 영향을 검토하기 위하여 온도를 $7^{\circ}C,\;15^{\circ}C,\;23^{\circ}C$로 달리하여 생육시키고, 자실체의 특성 및 조직의 미세구조 변화를 관찰 한 결과, 생육온도가 높을수록 갓의 두께는 얇아지고, 대의 두께 및 대의 길이는 길어졌으며, 버섯의 갓 색깔이 백색에 가깝게 변화하였다. 생육온도에 따른 자실체의 미세구조변화는 생육온도가 높아질수록 주름에 있어서 담자포자의 비산이 빠르고, 노화현상이 두드러졌다. 생육온도별로 느타리버섯 대부위의 물리적 특성을 조사한 결과 생육온도가 높을수록 경도는 낮아졌는데 이는 세포의 노화 및 균사의 밀도가 낮았기 때문으로 생각된다. 또한 대의 세포학적인 특정으로 액포화가 두드러져 생육온도가 높을수록 생육일수는 빨라지나 그만큼 노화가 쉽게 일어남을 확인하였다.