• Archives of design research
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• v.18 no.3 s.61
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• pp.55-62
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• 2005

Recently, the opening of the world economy and regional ization of national demand endless endeavors and investments to upbring design-industry for regional economic development. Our domestic commodities, declined in price competitiveness against China and Southeast Asian nations, need construction of brand image of commodities and consumers' response through expanded concernments in marketing spheres. The design-industry is a important means to strengthen competitiveness of the domestic industry through discrimination of commodities and creativity of high added value. Design-industry has some problems in circumstances; commodity development and marketing are below the level in the sphere of manufacture industry yet and businessmen are unwilling to invest demanded for development of new design. Establishment of the personal foundation, useful for accumulating competent designers' experiences and technologies, can not pass limit. In addition, a system and a policy to protect design-industry have a problem in effectiveness. Concrete strategies to activate design industry which meets social and cultural circumstances of Daegu and Gyeongbuk region are to establish policy for construction of specialists' infra, systematization of study & development of design, common ownership of information on design, and expansion of design company. The business to upbring design in the region should be operated to develop competitive commodities which is helpful to the regional economy and to increase value of the regional enterprises' brand. In addition, foundation of design should be expanded personal, material, and informational infra through design-centered so that they are helpful to activate economy of Daegu and Gyeongbuk through making design reformational cluster.

• Archives of Pharmacal Research
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• v.10 no.1
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• pp.42-49
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• 1987

This study is to evaluate the potential use of aclarubicin-loaded gelatin microspheres as an intravascular biodegradable drug delivery system for the regional cancer therapy. The diameter of the microspheres prepared by water in oil emulsion polymerization could be controlled by adjusting the stirring rate in the range of 10-50 $\mu$m : D(in $\mu$m) = -73.8 log (rpm) + 262.7. The addition of proteolytic enzyme increased the in vitro aclarubicin release but it did not change the amount of the initial burst release which reached about 45%. Microspheres injected intravenously into the mouse tail vein embolized only to the lung when observed by fluorescence microscopy. From histological examination following injection of gelatin microspheres into mouse femoral muscle, mild inflammation was observed from the appearance of neutrophils after 2 days and rapid repair process was confirmed thereafter. Biodegradation process of gelatin microspheres lodged on the pulmonary capillary bed was followed up by microscopic observation; degradation was taking place by about 36 hrs, followed by severe damage on the spheerical shape and microspheres was no longer found 10 days after injection.

• Archives of Plastic Surgery
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• v.42 no.4
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• pp.475-477
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• 2015

We report the case of a 33-year-old male who presented with a malignant melanoma on his anterior chest wall. The lesion was only found in the red ink pigment of the tattoo, as were several in-transit dermal metastases. Possible explanations include a pre-existing lesion which was seeded with red ink or the possibility of the red ink causing an inflammatory reaction leading to malignant transformation. This is the first reported case of a melanoma developing in the red ink pigment of a multi-colored tattoo.

• Archives of design research
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• v.15 no.4
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• pp.295-306
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• 2002

This research has focused on CI development by regional government, with emphasis on CI case study of Suncheon, Chonnam Province. Suncheon is located at the most east pan of Chonnam Province and famous as a starting point of temple Tour. CI for Suncheon City was studied and developed to promote the pride and love for Suncheon and to enhance the unique image of Suncheon to the tourists.

• Archives of Craniofacial Surgery
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• v.20 no.6
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• pp.401-404
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• 2019

Merkel cell carcinoma (MCC) is a relatively rare and aggressive cutaneous neuroendocrine malignancy. It is characterized by high rates of recurrence and metastasis, both to regional lymph nodes and to distant locations. Its characteristic clinical manifestation is a single, painless, hard, erythematous nodule on a sun-exposed area, particularly in older men. Surgical management of both the primary site and the sentinel lymph node is the standard of care. In this article, we describe the diagnosis and treatment of a case of MCC in the left cheek.

• Archives of Plastic Surgery
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• v.40 no.3
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• pp.263-266
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• 2013

Bleeding, is one of the most common postoperative complications after palatoplasty in patients with cleft palate. The purpose of this article is to present our experience using a Foley catheter balloon for perioperative palatoplasty bleeding management. A retrospective data analysis was performed for all cases of palatoplasty performed by the author from 1999 to 2012 that experienced postoperative hemorrhage. These patients were managed by utilizing posterior nasal compression with a Foley catheter balloon for the period 2006 to 2012. We have compared two methods (we use before 2006 the reoperative method) with regards to the later development of palatal fistulae and cases with reoperative hemostasis. The study found no statistically significant differences between the conventional and proposed method in relation to the development of palatal fistulae (P=0.7). These findings suggest that nasal packing using a Foley balloon is a safe and effective method for postoperative bleeding control after palatoplasty in patients with cleft palate.

• Archives of design research
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• v.3 no.1
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• pp.83-93
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• 1990

The constant evolution of society, culture and scientific technology, coupled with changes in life style and behavioral patterns, has led mankind to peroeive diverse needs for space. Particularly, the rapid structural change in the field of marketing has entailed changes in techinques for construction and presentation of space for an improved marketing environment. To satisfy such new, diverse needs for space, interior designers will have to redefine the "mankind and environmen( concept and examine their design methodology anew. The question of how to design available space for a certain purpose will remain a daunting task for designers in the future, as it has been in the past. In the pursuit of convenience and conformity to mankind's surroundings, every nation has, in common with other nations, basic design elements, design skills and other factors. In designing camercial space in a particular region, it is essential, however, to have a proper understanding of the social economic and cultural context indigenous to that region, as well as the impact on environmental and ecological change and marketing strategy. This study discusses design metholdology for the comming camercial space on the basis of the space concept and current status in Korea, with major emphasis on Korea's regional characteristics.

• Proceedings of The Korean Society of Agricultural and Forest Meteorology Conference
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• 2001.06a
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• pp.43-48
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• 2001

Many applications in the areas of agricultural, hydrological and environmental resource management require data over very large areas and with a high imaging frequency - monitoring crop growth, water stress, seasonal wetland flooding and natural vegetation development. This precludes the use of fine resolution data (Landsat, Spot) on the grounds of cost, accessibility and low imaging frequency. Meteorological satellites have the potential to fill this need, given their very wide spatial coverage, and high repeat imaging. The Remote Sensing Unit (RSU) at the Zambia Meteorological Department routinely receives, processes and archives imagery from both Meteosat and NOAA AVHRR satellites. Here I wish to present some examples of applications of these data sets that arise from the RSU work - relationships between rainfall and vegetation development as assessed by satellite, derived information and seasonal patterns of flooding in the Barotse floodplain and the Kafue flats. I also wish to outline ways in which a more widespread use of this data by the Zambian institutions canbe achieved.

• Archives of Pharmacal Research
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• v.24 no.2
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• pp.105-108
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• 2001

$\alpha$-Benzoyloxypaeoniflorin (1), a new antioxidant monoterpene $\alpha$-glycoside anomer was isolated from Paeonia suffruticosa along with known compounds, $\beta$-benzoyloxypaeoniflorin (2), paeonolide, paeoniflorin and mudanpioside H. The structure of 1 has been determined by comparing spectral data with those of $\beta$-Benzoyloxypaeoniflorin(2). Compound 1 exhibited moderately potent radical scavenging activity on DPPH radical.

• Archives of Pharmacal Research
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• v.26 no.10
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• pp.796-799
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• 2003

Two known farnesylacetone derivatives (1 and 2) were isolated from the Korean brown alga Sargassum sagamianum off Jeju Island, Korea. Compounds 1 and 2 were identified as (5E,10Z)-6, 10, 14-trimethylpentadeca-5, 10-dien-2, 12-dione and (5E,9E,13E)-6, 10,4-trimethylpentadeca-5,9,13-trien-2,12-dione, respectively, by comparison with the literature data. Compounds 1 and 2 showed moderate acetylcholinesterase and butyrylcholinesterase inhibitory activities with $IC_{50}$ values of 65.0∼48.0 and 34.0∼23.0 $\muM$, respectively.