• Title/Summary/Keyword: regenerative process

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The Effect of Ginseng on Muscle Injury and Inflammation

  • Alvarez A.I.;Oliveira A. C. Cabral de;Perez A.C.;Vila L.;Ferrando A.;Prieto J.G.
    • Proceedings of the Ginseng society Conference
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    • 2002.10a
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    • pp.159-175
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    • 2002
  • The effect of Panax ginseng administration in muscle inflammatory process induced after eccentric exercise, that causes myofibrillar disruption, was studied. Changes in lipid peroxidation, inflammation, glycogen levels in muscle and release of myocellular proteins to blood were measured. The analyses were performed immediately after eccentric exercise and over week since this period are necessary for the muscle damage-repair cycle. The ginseng extract $(100\;mg\;kg^{-1})$ was orally administered to rats for three months, before the eccentric exercise performance. The results showed the protective role of ginseng against skeletal muscle damage. This effect could be associated with their membrane stabilising capacity since creatine kinase (CK) activity was significantly decreased 96 h post-exercise from $523{\pm}70\;to\;381{\pm}53$ and 120 h post-exercise from $443{\pm}85\;to\;327{\pm}75$ in treated animals. ${\beta}-glucuronidase$ activity, as indicator of inflammation, showed a significant reduction of about $15-25\%$ in soleus, vastus and triceps in these post-exercise times. The lipid peroxidation, measured by malondyaldehyde levels, was significantly decreased in the 24 h postexercise period in soleus and vastus intermedius muscles and on the recovery period. Finally ginseng administration reduced significantly the decrease of the glycogen levels immediately after exercise and when the regenerative process took place (72-168 h post exercise). Collectively, the results have showed that ginseng did not inhibit the vital inflammatory response process associated with the muscle damage-repair cycle but presumably ameliorate the injury.

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Removal of S $O_{2}$ and NO by Dry Sorbent(II) - Efficiency of Cu-Ce and Cu-7Al - (건식법에 의한 이산화황과 산화질소의 제거(II) - Cu-Ce 및 Cu-7Al의 효율 -)

  • 신창섭
    • Journal of Korean Society for Atmospheric Environment
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    • v.9 no.4
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    • pp.288-294
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    • 1993
  • Flue gas control systems for small-scale combustors must be designed to provide highly effective removal of three criteria pollutants (S $O_{2}$, N $O_{x}$ and particulate matter), and must be safe, reliable and small. These requirements make dry, regenerative clean-up process particularly attractive and this paper describes a new concept for integrated pollutant control : a filter comprised of layered, gas permeable membranes that act as an S $O_{2}$ sorbant, a N $O_{x}$ reduction catalyst and a particulate filter. A mixed metal oxide sorbent, Cu-Ce was used as a sorbent/catalyst and the activity was compared with Cu-7Al. The S $O_{2}$ removal eficiency of Cu-Ce was increased with temperature increase up to 500$^{\circ}$C and the catalytic activity for NO was higher than that of Cu-7Al. By the sulfation of Cu-Ce, the reduction activity was increased at the temperature higher than 350$^{\circ}$C. The regeneration of Cu-Ce was very fast and some amount of elemental sulfar was found.

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Energy Regenerative 3-Phase Bidirectional AC-DC Converter for the Secondary Battery Charge/Discharge System (에너지 회수가 가능한 2차전지 충방전시스템용 3상 양방향 AC-DC 컨버터)

  • Lim, Seung-Beom;Won, Hwa-Young;Chae, Soo-Yong;Seo, Young-Min;Lee, Jun-Young;Ko, Jong-Sun;Hong, Soon-Chan
    • Proceedings of the KIPE Conference
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    • 2008.06a
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    • pp.259-261
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    • 2008
  • The electronic products such as laptop PC, cellular phone, robots and etc. need the DC power source. Recently, the secondary battery is frequently used as the portable DC power source and it needs forming process. In this paper, we proposed the bidirectional converter that the battery can be charged with high power factor and the discharged energy is regenerated into AC power source. In the charging mode, the converter acts as the boost rectifier. And the AC input current is controlled in phase with the AC input voltage. As a result, the power factor is improved nearly to unity. In the discharging mode, the DC power of battery wasted in resistor is regenerated to the AC bus line. Finally, the validity of the proposed bidirectional converter is verified by computer simulations and experimentation.

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Stem cell therapy in animal models of inherited metabolic diseases (유전성 대사 질환 동물 모델에서의 줄기 세포 치료)

  • Choi, Dongho;Lee, Dong Hwan;Jung, Sung-Chul
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.5 no.1
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    • pp.116-125
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    • 2005
  • Orthotopic liver transplantation is the treatment of choice for inherited metabolic diseases. However, the supply of donor organs is limiting and therefore many patients cannot benefit from this therapy. In contrast, hepatocytes can be isolated from a single donor liver. They can be transplanted into several recipients, and this procedure may help overcome the shortage of donor livers. A great deal of work with animal models indicates that hepatocytes transplanted into the liver or spleen can survive, function, and participate in the normal regenerative process. Recent clinical studies suggest that hepatocyte transplantation may be useful for bridging patients to whole organ transplantation and for providing metabolic support during liver failure and for replacing whole organ transplantation in certain inherited metabolic diseases. Nowadays, hepatocytes from various stem cells have been regarded as an another cell source for treatment of inherited metabolic diseases. Although cell therapy using stem cells for inherited metabolic disease patient has been accepted only as an experimental trial yet, hepatocytes from stem cells can solve a lot of obstacles in the treatment of inherited metabolic diseases.

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A Study on the Eco-Tecnique of EcoCenter - Focused on the Building Material and Solar System - (에코센터의 생태건축기술에 관한 연구 - 건축재료와 태양에너지활용시스템을 중심으로 -)

  • Choi, Young-Ho;Shim, Woo-Gab
    • KIEAE Journal
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    • v.4 no.2
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    • pp.65-72
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    • 2004
  • Ecological architecture enables people to recycle and reuse architectural resources within the category of ecosystem and also to minimize the effect on environment in a whole process, including architectural planning, usage and exhaustion to use sustainable energies. Rammed earth wall construction method utilized in EcoCenter located in Crystalwaters ecological village in Austrailia is a good example, which maximizes its advantages and also covers its limits to use soil and wood as structural resources. In a case of wood, they used non-treated timber to minimize environmental load and utilized used materials in openings. In the roofs, aluminum coated steel which is plated with zinc collects rain effectively even though it is not regenerable. Nontoxic finishes and insulation in floor and ceiling with used papers are able to minimize its environmental load. Solar energy system applied in EcoCenter enables them to market extra energy with electricity companies as well as support needs of its own buildings to utilize photovoltaic panel system with PV panels. Passive solar system is planned effectively in heating and cooling to apply regenerative walls in a use of rammed earth wall construction and natural ventilation systems through openings.

Effects of Sagunjatang-Ga-Nokyong on Neurologic Recovery in Rats after Spinal Cord Injury

  • Kim, Hyun-Seok;Yoon, Il-Ji
    • The Journal of Korean Medicine
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    • v.29 no.5
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    • pp.1-13
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    • 2008
  • Objective : This study is investigate the effects of Sagunjatang-Ga-Nokyong(SGJ-NY) treatment on regenerative responses of corticospinal tract(CST) axons in the injured spinal cord. Methods :Using rats, we damaged their spinal cord, and then applied SGJ-NY extract to the lesion. Then we observed GAP-43 and NGF protein, astrcyte, axonal regeneration responses and axonal elongation. Result :Determination of GAP-43 and NGF protein levels were increased. And increased proliferation of astrocyte and enhanced processes in astrocytes were observed by SGJ-NY treatment. Higher number of astrocytes within the injury cavity in SGJ-NY treated group were showed, yet CSPG proteins were a weaker staining in the cavity in SGJ-NY. CST axons extended into the cavity and to the caudal area in SGJ-NY treated group were increased. Conclusion : SGJ-NY treatment might increase neural activity in the injured spinal cord tissue, and improved axonal regeneration responses. In this process, activation of astrocytes may play a role in promoting enhanced axonal elongation. the current study show that SGJ-NY exerts positive activity on inducing nerve regeneration responses by elevating neural tissue migration activities.

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Range Extension of Light-Duty Electric Vehicle Improving Efficiency and Power Density of IPMSM Considering Driving Cycle (주행 사이클을 고려한 IPMSM의 효율 및 출력 밀도 개선으로 경량 전기 자동차의 주행거리 연장)

  • Kim, Dong-Min;Jung, Young-Hoon;Lim, Myung-Seop;Sim, Jae-Han;Hon, Jung-Pyo
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.65 no.12
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    • pp.2197-2210
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    • 2016
  • Recently, the trend of zero emissions has increased in automotive engineering because of environmental problems and regulations. Therefore, the development of battery electric vehicles (EVs), hybrid/plug-in hybrid electric vehicles (HEVs/PHEVs), and fuel cell electric vehicles (FCEVs) has been mainstreamed. In particular, for light-duty electric vehicles, improvement in electric motor performance is directly linked to driving range and driving performance. In this paper, using an improved design for the interior permanent magnet synchronous motor (IPMSM), the EV driving range for the light-duty EV was extended. In the electromagnetic design process, a 2D finite element method (FEM) was used. Furthermore, to consider mechanical stress, ANSYS Workbench was adopted. To conduct a vehicle simulation, the vehicle was modeled to include an electric motor model, energy storage model, and regenerative braking. From these results, using the advanced vehicle simulator (ADVISOR) based on MATLAB Simulink, a vehicle simulation was performed, and the effects of the improved design were described.

A Study for Liquid Rocket Engine System Layout and Assembly (액체로켓 엔진시스템 배치 및 조립에 관한 연구)

  • Ryu Chul-Sung;Chung Yong-Hyun;Oh Myung-Hwan;Nam Kyoung-O;Moon Jong-Hoon;Seol Woo-Seok
    • Journal of the Korean Society of Propulsion Engineers
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    • v.8 no.4
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    • pp.102-108
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    • 2004
  • A layout of regenerative liquid rocket engine using turbo pump has been designed for development of high performance liquid rocket engine. each components of engine system was placed by considering assembly and characteristic. first stage engine system is controled by one plane of axis gimballing and composed of four engine assembly to cluster with launch vehicle. second stage engine system is controled by two plane of axis gimballing and composed of one engine assembly. assembly and disassembly Processes and required program have been developed. various shape of instruments were also developed for carrying out assembly and disassembly process efficiently.

Neurogenesis in the Adult Brain (성체 뇌 조직의 신경발생)

  • Kim, Sik-Hyun;Kim, Sang-Su
    • PNF and Movement
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    • v.6 no.3
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    • pp.37-51
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    • 2008
  • Purpose : This paper focuses on the emerging concept that adult central nervous system neurogenesis can be regulated by various physical activity, enriched environment, and pathological conditions. Neurogenesis-the production of new neuron-is an ongoing process that persists in the adult brain of mammalian, including humans. Result : The adult brain was thought be limited in its regenerative function. However, this concepts changed, recent evidence of neurogenesis in certain adult brain areas such as SVZ(subventricular zone) and SGZ(subgranular zone) in hippocampus, raised possibility for improved treatment for patient with stroke. Neural plasticity has an adaptive purpose, because an ability of the brain to change in response to peripheral stimulation, physical activity, experience, and injury. Conclusions : The major function of the neurogenesis in adult brain seems to be replacing the neuron that die regularly in discrete adult brain regions. These cells are capable of functionally integrating into neighboring neural cells, and reconnecting to the correct neural networks. This review suggest that various intervention, including physical activity, voluntary movement training, skilled forelimb reaching training, and enriched environment, induced neural cell production in certain adult brain, and associated with functional recovery after stroke.

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A Study on the Optimal Flash-Point of WDF Production (유화유 생산의 적정 인화점에 관한 연구)

  • Lee, Jin;Kim, Hwaseong
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.33 no.4
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    • pp.310-314
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    • 2020
  • Although waste oil derived fuel (WDF) production technology was developed under a government initiative ~10 years ago, it became stagnant owing to the small size of participating companies, residents' rejection of foul odor, and the nature of the technology for recycling waste that was avoided. However, this subject is under the spotlight again because of recent developments, such as garbage crisis. In particular, plastic is the most difficult waste to dispose of, with more than 4 million tons of plastic waste produced every year according to statistics from the Ministry of Environment. The most effective method for treating plastic waste is to produce WDF through low temperature thermal decomposition. The WDF includes several volatile ingredients that mostly limit the use of fuel for boilers, owing to safety concerns. In particular, flash point is legally stipulated because of secondary contamination in the distribution process and the risk of fire and explosion. It is required that external shipments (distribution) should be maintained in the range of at least 30~60℃ (excluding explosion prevention facilities) for diesel power generation. Therefore, this study seeks to find the flash point that is best suited to WDFs produced from plastic waste.