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Antioxidative Activity and Antiaging Effects of Duchesnea indica (Andr.) Focke extract (뱀딸기추출물의 항산화 활성 및 항노화에 관한 연구)

  • Roh, Eon-Joo;Park, Si-Hyang;Hwang, Su-Mi;Ro, Hyeon-Su;Kim, Byung-Kwan
    • Journal of the Korean Applied Science and Technology
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    • v.27 no.4
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    • pp.539-544
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    • 2010
  • In this study, we evaluated the anti-oxidative, anti-wrinkle and whitening effect of Duchesnea indica (Andr.) Focke extract. Duchesnea indica (Andr.) Focke was extracted by two different solvents which were n-hexane and ethyl acetate. The anti-oxidant activity was measured by free radical scavenging activity using DPPH (1,1-diphenyl-2-picrylhydrazyl radical). And the inhibitory activities of tyrosinase for whitening effect and collagenase for anti-wrinkle were investigated. For anti-oxidant activity and whitening activity, ethyl acetate fraction of Duchesnea indica (Andr.) Focke extract showed more significant activity than n-hexane fraction of Duchesnea indica (Andr.) Focke extract. For anti-wrinkle activity, ethyl acetate fraction of Duchesnea indica (Andr.) Focke extract exhibited strong inhibition effects compared with reference. Therefore, Duchesnea indica (Andr.) Focke extract may be useful as a new antioxidant and anti-aging agent.

A NUMERICAL STUDY ON FLOWS IN A FUEL TANK WITH BAFFLES AND POROUS MEDIA TO REDUCE SLOSHING NOISE (연료탱크 슬로싱 소음 저감을 위한 배플 및 다공성 물질 설치에 따른 유동해석 연구)

  • Lee, Sang-Hyuk;Hur, Nahm-Keon
    • Journal of computational fluids engineering
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    • v.14 no.2
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    • pp.68-76
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    • 2009
  • The sloshing tank causes the instability of the fluid flows and the fluctuation of the impact pressure by the liquid on the tank. These flow characteristics inside the sloshing tank can generate the uncomfortable sloshing noise. In the present study, a numerical analysis for the reduction of a fuel tank sloshing noise was performed. To simulate the flow characteristics in a sloshing tank with partially filled liquid, a VOF method was used for interfacial flows by applying a momentum source term for the sloshing motion in a non-inertial reference frame. This numerical method was verified by comparing its results with the available experimental data. For the reduction of the sloshing noise, the horizontal and vertical baffles and porous media inside a sloshing tank were considered and numerically analyzed in the present study. For various installations of these baffles and porous media, the characteristics of the liquid behavior in the sloshing tank were obtained along with the impact pressure on the wall and the height of the free surface along the wall. These basic results can be used for the design of the actual vehicular fuel tank with the reduced sloshing noise.

Skin depth profiling by using fiber optic probes in the near infrared

  • Woo, Young-Ah;jung, Suh-Eun;Kim, Hyo-Jin
    • Proceedings of the SCSK Conference
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    • 2003.09b
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    • pp.218-218
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    • 2003
  • Recently we showed the prototype portable device for the determination of human skin moisture by using near infrared spectroscopy. In order to optimize the acquiring condition of NIR spectrum of skin and control the target information of water depending the site such as epidermis and dermis, skin depth profiling was investigated changing the distance between illuminations and receiving of radiation in the terminal of fiber probe. The colleted light information could be controlled by changing the distance of the fiber optic probes. It was confirmed that the longer distance we used, the deeper site from the skin surface we could get information from in this study. Four kinds of probes with distances such as 0.03 mm, 0.1 mm, 0.5 mm, and 1.0 mm were used. In addition, the gap size from 0.3 mm to 3.0 mm was studied to control the intensity of water absorbance effectively and to avoid saturation of water absorption. We also investigated the reference materials depending the reflectance ratio for water absorption not to be saturated because of the strong absorptivity of water. Furthermore, spectroscopic information regarding free water and bound water around 1850 nm was investigated by using the different distance of fiber optic probes. This study would be great help to control the spectroscopic information of water to be measured depending the site where water exists.

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Constructing Proteome Reference Map of the Porcine Jejunal Cell Line (IPEC-J2) by Label-Free Mass Spectrometry

  • Kim, Sang Hoon;Pajarillo, Edward Alain B.;Balolong, Marilen P.;Lee, Ji Yoon;Kang, Dae-Kyung
    • Journal of Microbiology and Biotechnology
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    • v.26 no.6
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    • pp.1124-1131
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    • 2016
  • In this study, the global proteome of the IPEC-J2 cell line was evaluated using ultra-high performance liquid chromatography coupled to a quadrupole Q Exactive Orbitrap mass spectrometer. Proteins were isolated from highly confluent IPEC-J2 cells in biological replicates and analyzed by label-free mass spectrometry prior to matching against a porcine genomic dataset. The results identified 1,517 proteins, accounting for 7.35% of all genes in the porcine genome. The highly abundant proteins detected, such as actin, annexin A2, and AHNAK nucleoprotein, are involved in structural integrity, signaling mechanisms, and cellular homeostasis. The high abundance of heat shock proteins indicated their significance in cellular defenses, barrier function, and gut homeostasis. Pathway analysis and annotation using the Kyoto Encyclopedia of Genes and Genomes database resulted in a putative protein network map of the regulation of immunological responses and structural integrity in the cell line. The comprehensive proteome analysis of IPEC-J2 cells provides fundamental insights into overall protein expression and pathway dynamics that might be useful in cell adhesion studies and immunological applications.

Comparative Studies on the Composition of Korean Human and Cow's Milk (I) -Amino Acid Composition of Human and Cow's Milk of Korea- (한국인(韓國人) 모유(母乳)와 우유(牛乳)의 성분(成分) 조성(組成)에 관(關)한 비교(比較) 연구(硏究) (I) -한국인(韓國人) 모유(母乳)와 우유중(牛乳中)의 Amino산(酸) 조성(組成)에 관(關)한 연구(硏究)-)

  • Ko, Young-Su;Kim, Jung-Ja;Han, In-Ja
    • Journal of Nutrition and Health
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    • v.3 no.2
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    • pp.87-94
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    • 1970
  • The amino acid composition of human and cow's milk represents a standard of reference in infantnutrition. The amino acid compositions determined by automatic amino acid analyzer, Yanagimote Model LC-5. Protein in the human and cow's milk were found to be hydrolyzed to yield free amino acids. Qualitative data for free amino acids in the milk are as follows: 1) Amounts of acidic amino acids such as glutamic and aspartic acid in cow's milk were obserbed to be about 2 times compared with human milk and it is considered that the abundance in these amino acids may contribute significantly to the specific flavor of cow's milk. 2) It is much interesting that in the human milk the contents of sulfur-containing amino acids were high comparatively better than cow's milk; cystine was found to be 3 times ana methionine, 2 times. 3) In the human milk a high content of some essential amino acids such as threonine, isoleucine and leucine was demonstrated and a specific flavor sweet amino acids. 4) Large amounts of basic amino acid such as histidine was found to occur in human milk and arginine in cow's milk.

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Damage evaluation of RC beams strengthened with hybrid fibers

  • Sridhar, Radhika;Prasad, Ravi
    • Advances in concrete construction
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    • v.8 no.1
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    • pp.9-19
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    • 2019
  • This paper describes an experimental investigation on hybrid fiber reinforced concrete (HYFRC) beams. And the main aim of this present paper is to examine the dynamic characteristics and damage evaluation of undamaged and damaged HYFRC beams under free-free constraints. In this experimental work, totally four RC beams were cast and analyzed in order to evaluate the dynamic behavior as well as static load behavior of HYFRCs. Hybrid fiber reinforced concrete beams have been cast by incorporating two different fibers such as steel and polypropylene (PP). Damage of HYFRC beams was obtained by cracking of concrete for one of the beams in each set under four-point bending tests with different percentage variation of damage levels as 50%, 70% and 90% of maximum ultimate load. And the main dynamic characteristics such as damping, fundamental natural frequencies, mode shapes and frequency response function at each and every damage level has been assessed by means of non-destructive technique (NDT) with hammer excitation. The fundamental natural frequency and damping values obtained through dynamic tests for HYFRC beams were compared with control (reference) RC beam at each level of damage which has been acquired through static tests. The static experimental test results emphasize that the HYFRC beam has attained higher ultimate load as compared with control reinforced concrete beam.

Vibration response and wave propagation in FG plates resting on elastic foundations using HSDT

  • Nebab, Mokhtar;Atmane, Hassen Ait;Bennai, Riadh;Tounsi, Abdelouahed;Bedia, E.A. Adda
    • Structural Engineering and Mechanics
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    • v.69 no.5
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    • pp.511-525
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    • 2019
  • This paper presents an analytical study of wave propagation in simply supported graduated functional plates resting on a two-parameter elastic foundation (Pasternak model) using a new theory of high order shear strain. Unlike other higher order theories, the number of unknowns and governing equations of the present theory is only four unknown displacement functions, which is even lower than the theory of first order shear deformation (FSDT). Unlike other elements, the present work includes a new field of motion, which introduces indeterminate integral variables. The properties of the materials are assumed to be ordered in the thickness direction according to the two power law distributions in terms of volume fractions of the constituents. The wave propagation equations in FG plates are derived using the principle of virtual displacements. The analytical dispersion relation of the FG plate is obtained by solving an eigenvalue problem. Numerical examples selected from the literature are illustrated. A good agreement is obtained between the numerical results of the current theory and those of reference. A parametric study is presented to examine the effect of material gradation, thickness ratio and elastic foundation on the free vibration and phase velocity of the FG plate.

Antioxidant Compounds from Distylium racemosum Leaves

  • Park, Youngki;Lee, Wi Young;Ahn, Jin Kwon;Lee, Hak-Ju;Chin, Hwi Seung;Kwon, Young Jin
    • Journal of the Korean Wood Science and Technology
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    • v.31 no.6
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    • pp.67-72
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    • 2003
  • The leaves of D. racemosum showed strong DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity and the order of the radical scavenging activity against DPPH radical is ethyl acetate (EtOAc) fraction>crude extracts>residue fraction>hexane fraction>ether fraction, under the experimental conditions. Since EtOAc fraction has highest antioxidative activity among these fractions, the isolation was performed from the EtOAc fraction of the leaves of D. racemosum and four phenolic compounds were isolated and identified as follows: methyl gallate, kaempferol, quercetin and quercitrin. The free radical scavenging activities of these compounds were 79.9%, 93.1%, 93.6% and 66.7% at 10 ㎍/ml, respectively. The IC50 of compound 1, compound 2, compound 3 and compound 4 were 6.1, 4.1, 3.6 and 6.5 ㎍/ml, respectively. These compounds have higher antioxidative activity compared with reference compounds, ascorbic acid (IC50 = 9.6 ㎍/ml).

A nonlocal integral Timoshenko beam model for free vibration analysis of SWCNTs under thermal environment

  • Liani, Mohamed;Moulay, Noureddine;Bourada, Fouad;Addou, Farouk Yahia;Bourada, Mohamed;Tounsi, Abdelouahed;Hussain, Muzamal
    • Advances in materials Research
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    • v.11 no.1
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    • pp.1-22
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    • 2022
  • In this paper, the nonlocal integral Timoshenko beam model is employed to study the free vibration characteristics of singled walled carbon nanotubes (SWCNTs) including the thermal effect. Based on the nonlocal continuum theory, the governing equations of motion are formulated by considering thermal effect. The influences of small scale parameter, the chirality of SWCNTs, the vibrational mode number, the aspect ratio of SWCNTs and temperature changes on the thermal vibration properties of single-walled nanotubes are examined and discussed. Results indicate significant dependence of natural frequencies on the nonlocal parameter, the temperature change, the aspect ratio and the chirality of SWCNTs. This work should be useful reference for the application and the design of nanoelectronics and nanoelectromechanical devices that make use of the thermal vibration properties of SWCNTs.

Applied Koopmanistic interpretation of subcritical prism wake physics using the dynamic mode decomposition

  • Cruz Y. Li;Xisheng Lin;Gang Hu;Lei Zhou;Tim K.T. Tse;Yunfei Fu
    • Wind and Structures
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    • v.37 no.3
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    • pp.191-209
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    • 2023
  • This work investigates the subcritical free-shear prism wake at Re=22,000 by the Koopman analysis using the Dynamic Mode Decomposition (DMD) algorithm. The Koopman model linearized nonlinearities in the stochastic, homogeneous anisotropic turbulent wake, generating temporally orthogonal eigen tuples that carry meaningful, coherent structures. Phenomenological analysis of dominant modes revealed their physical interpretations: Mode 1 renders the mean-field dynamics, Modes 2 describes the roll-up of the Strouhal vortex, Mode 3 describes the Bloor-Gerrard vortex resulting from the Kelvin-Helmholtz instability inside shear layers, its superposition onto the Strouhal vortex, and the concurrent flow entrainment, Modes 6 and 10 describe the low-frequency shedding of turbulent separation bubbles (TSBs) and turbulence production, respectively, which contribute to the beating phenomenon in the lift time history and the flapping motion of shear layers, Modes 4, 5, 7, 8, and 9 are the relatively trivial harmonic excitations. This work demonstrates the Koopman analysis' ability to provide insights into free-shear flows. Its success in subcritical turbulence also serves as an excellent reference for applications in other nonlinear, stochastic systems.