• Title/Summary/Keyword: reference size

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Accuracy of genotype imputation based on reference population size and marker density in Hanwoo cattle

  • Lee, DooHo;Kim, Yeongkuk;Chung, Yoonji;Lee, Dongjae;Seo, Dongwon;Choi, Tae Jeong;Lim, Dajeong;Yoon, Duhak;Lee, Seung Hwan
    • Journal of Animal Science and Technology
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    • v.63 no.6
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    • pp.1232-1246
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    • 2021
  • Recently, the cattle genome sequence has been completed, followed by developing a commercial single nucleotide polymorphism (SNP) chip panel in the animal genome industry. In order to increase statistical power for detecting quantitative trait locus (QTL), a number of animals should be genotyped. However, a high-density chip for many animals would be increasing the genotyping cost. Therefore, statistical inference of genotype imputation (low-density chip to high-density) will be useful in the animal industry. The purpose of this study is to investigate the effect of the reference population size and marker density on the imputation accuracy and to suggest the appropriate number of reference population sets for the imputation in Hanwoo cattle. A total of 3,821 Hanwoo cattle were divided into reference and validation populations. The reference sets consisted of 50k (38,916) marker data and different population sizes (500, 1,000, 1,500, 2,000, and 3,600). The validation sets consisted of four validation sets (Total 889) and the different marker density (5k [5,000], 10k [10,000], and 15k [15,000]). The accuracy of imputation was calculated by direct comparison of the true genotype and the imputed genotype. In conclusion, when the lowest marker density (5k) was used in the validation set, according to the reference population size, the imputation accuracy was 0.793 to 0.929. On the other hand, when the highest marker density (15k), according to the reference population size, the imputation accuracy was 0.904 to 0.967. Moreover, the reference population size should be more than 1,000 to obtain at least 88% imputation accuracy in Hanwoo cattle.

Effects of the Reference Sample Size on the Performance of the Two-Sample Rank Detector (두 표본 순위 검파에서 기준 표본 크기가 검파기 성능에 미치는 영향)

  • Bae, Jinsoo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.40 no.8
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    • pp.1515-1517
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    • 2015
  • The effects of the reference sample size on the detection probability of the two-sample rank detector is investigated in this paper. The larger reference sample size shows the better performance of the detector. The effect is also shown to be saturated as the reference sample size becomes larger.

Comparison of prediction accuracy for genomic estimated breeding value using the reference pig population of single-breed and admixed-breed

  • Lee, Soo Hyun;Seo, Dongwon;Lee, Doo Ho;Kang, Ji Min;Kim, Yeong Kuk;Lee, Kyung Tai;Kim, Tae Hun;Choi, Bong Hwan;Lee, Seung Hwan
    • Journal of Animal Science and Technology
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    • v.62 no.4
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    • pp.438-448
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    • 2020
  • This study was performed to increase the accuracy of genomic estimated breeding value (GEBV) predictions for domestic pigs using single-breed and admixed reference populations (single-breed of Berkshire pigs [BS] with cross breed of Korean native pigs and Landrace pigs [CB]). The principal component analysis (PCA), linkage disequilibrium (LD), and genome-wide association study (GWAS) were performed to analyze the population structure prior to genomic prediction. Reference and test population data sets were randomly sampled 10 times each and precision accuracy was analyzed according to the size of the reference population (100, 200, 300, or 400 animals). For the BS population, prediction accuracy was higher for all economically important traits with larger reference population size. Prediction accuracy was ranged from -0.05 to 0.003, for all traits except carcass weight (CWT), when CB was used as the reference population and BS as the test. The accuracy of CB for backfat thickness (BF) and shear force (SF) using admixed population as reference increased with reference population size, while the results for CWT and muscle pH at 24 hours after slaughter (pH) were equivocal with respect to the relationship between accuracy and reference population size, although overall accuracy was similar to that using the BS as the reference.

Fast Frame Selection Method for Multi-Reference and Variable Block Motion Estimation (다중참조 및 가변블록 움직임 추정을 위한 고속 참조영상 선택 방법)

  • Kim, Sung-Dae;SunWoo, Myung-Hoon
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.45 no.6
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    • pp.1-8
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    • 2008
  • This paper introduces three efficient frame selection schemes to reduce the computation complexity for the multi-reference and variable block size Motion Estimation (ME). The proposed RSP (Reference Selection Pass) scheme can minimize the overhead of frame selection. The MFS (Modified Frame Selection) scheme can reduce the number of search points about 18% compared with existing schemes considering the motion of image during the reference frame selection process. In addition, the TPRFS (Two Pass Reference frame Selection) scheme can minimize the frame selection operation for the variable block size ME in H.264/AVC using the character of selected reference frame according to the block size. The simulation results show the proposed schemes can save up to 50% of the ME computation without degradation of image Qualify. Because the proposed schemes can be separated from the block matching process, they can be used with any existing single reference fast search algorithms.

Fast Multiple Reference Frame Selection Method for Motion Estimation and Compensation in Video Coding (동영상 부호화의 움직임 추정 및 보상을 위한 고속 다중 참조 프레임 선택 기법)

  • Kim, Jae-Hoon;Kim, Myoung-Jin;Hong, Min-Cheol
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.32 no.11C
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    • pp.1066-1072
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    • 2007
  • In this paper, we propose a fast multiple reference frame selection method for motion estimation and compensation in video coding. Reference frames selected as an optimal reference frame by variable block sizes motion estimation have the statistical characteristic that was based on block size. Using the statistical characteristic, reference frames for smaller block size motion estimation can be selected from reference frame which was decided as an optimal one for the upper layer block size. Simulation results show that the proposal method decreased the computations about 60%. Nevertheless, PSNR and bit rate were almost same as the performances of original H.264 multiple reference motion estimation.

A Web Cache Replacement Technique of the Divided Scope Base that Considered a Size Reference Characteristics of Web Object

  • Seok, Ko-Il
    • Proceedings of the Korea Contents Association Conference
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    • 2003.05a
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    • pp.335-339
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    • 2003
  • We proposed a Web cache replacement technique of a divided scope base that considered a size reference characteristics of a Web object for efficient operation of a Web base system and, in this study, analyzed performance of the replacement technique that proposed it though an experiment. We analyzed a reference characteristics of size to occur by a user reference characteristics through log analysis of a Web Base system in an experiment. And we divide storage scope of a cache server as its analysis result and tested this replacement technique based n divided scope. The proposed technique has a flexibility about a change of a reference characteristics of a user. Also, experiment result, we compared it with LRU and the LRUMIN which were an existing replacement technique and confirmed an elevation of an object hit ratio.

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Fast Reference Region Adjustment Using Sizing Factor Generation in Correlation-Based Image Tracking

  • Sung, Si-Hun;Chien, Sung-Il
    • Journal of Electrical Engineering and information Science
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    • v.3 no.2
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    • pp.230-238
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    • 1998
  • When size and shape of moving object have been changed, a correlator often accumulates walk-off error. A success of correlation-based tracking largely depends on choosing suitable window size and position and thus transferring the proper reference image to the next frame. For this, we propose the Adaptive Window Algorithm with Four-Direction Sizing Factors (AWA-FSF) for fast adjusting a reference region to enhance reliability of correlation-based image tracking in complex cluttered environments. Since the AWA-FSF is capable of adjusting a reference image size more rapidly and properly, we can minimize the influence of complex background and clutter. In addition, we can finely tune the center point of the reference image repeatedly after main tracking process. Thus we have increased stability and reliability of correlation-based image tracking. We tested performance of the AWA-FSF using 45 real image sequences made of over 3400 images and had the satisfied results for most of them.

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Liver Size Measurement Method by Ultrasonography and Reference Range based on Normal Adult Physique Index (초음파검사에 의한 간 크기 측정방법 및 정상 성인의 체격지수별 참조범위)

  • Kim, Yong-Kyun;Han, Dong-Kyoon
    • Journal of radiological science and technology
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    • v.41 no.1
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    • pp.13-24
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    • 2018
  • Liver size is an important component in the diagnosis and follow-up of diffuse liver disease when testing for liver disease using ultrasonography. However, difficulties lies in determining the presence of hepatomegaly and liver atrophy because the method used for measuring liver size differs from one examiner to another and there is no relevant standard based on body build. The present study aims to propose a more objective method for liver size measurement and a reference range based on body build. A total of 260 normal adults (130 males, 130 females) participated in the study. Ultrasonography was performed in all participants to measure the size of the right lobe, left lobe, quadrate lobe, and caudate lobe of liver. Based on Physique Index(PI), a value derived from multiplying weight(kg) by height($m^2$), size of physique was divided into three groups including Group I with PI<150, Group II with $150{\leq}PI{\leq}250$, and Group III with PI>250. Thus, mean liver size by PI and a reference range with 95% reliability were suggested. The superoinferior diameter of right lobe was $12.34{\pm}1.18cm$ in males and $11.07{\pm}0.93cm$ in females, and its reference range was 10.64~11.0cm for Group I, 11.78~12.12cm for Group II, and 13.02~13.84cm for Group III. The anteroposterior diameter(T) of left lobe was $5.93{\pm}1.09cm$ in males and $5.18{\pm}0.99cm$ in females, and its reference range was 4.77~5.17cm for Group I, 5.49~5.79cm for Group II, and 6.68~7.44cm for Group III. The transverse diameter was $3.51{\pm}0.60cm$ in male participants and $3.42{\pm}0.49cm$ in female participants and its reference range was 3.29~3.51cm for Group I, 3.36~3.55cm for Group II, and 3.52~4.0cm for Group III. The caudate lobe index was $11.65{\pm}2.88cm^2$ in males and $9.62{\pm}2.18cm^2$ in females and its reference range was $8.83{\sim}9.75cm^2$ for Group I, $10.62{\sim}11.47cm^2$ for Group II, and $11.89{\sim}14.26cm^2$ for Group III. As a basic measurement method of liver size, the present study suggests measuring the superoinferior diameter for right liver lobe, the anteroposterior diameter for left liver lobe, the transverse diameter for quadrate lobe, and the caudate lobe index for caudate lobe. It is expected that this method along with its relevant reference range can be used as useful indicators in determining hepatomegaly and liver atrophy upon the diagnosis and follow-up testing of diffuse liver disease.

Dynamic Reference Scheme with Improved Read Voltage Margin for Compensating Cell-position and Background-pattern Dependencies in Pure Memristor Array

  • Shin, SangHak;Byeon, Sang-Don;Song, Jeasang;Truong, Son Ngoc;Mo, Hyun-Sun;Kim, Deajeong;Min, Kyeong-Sik
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.15 no.6
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    • pp.685-694
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    • 2015
  • In this paper, a new dynamic reference scheme is proposed to improve the read voltage margin better than the previous static reference scheme. The proposed dynamic reference scheme can be helpful in compensating not only the background pattern dependence but also the cell position dependence. The proposed dynamic reference is verified by simulating the CMOS-memristor hybrid circuit using the practical CMOS SPICE and memristor Verilog-A models. In the simulation, the percentage read voltage margin is compared between the previous static reference scheme and the new dynamic reference scheme. Assuming that the critical percentage of read voltage margin is 5%, the memristor array size with the dynamic scheme can be larger by 60%, compared to the array size with the static one. In addition, for the array size of $64{\times}64$, the interconnect resistance in the array with the dynamic scheme can be increased by 30% than the static reference one. For the array size of $128{\times}128$, the interconnect resistance with the proposed scheme can be improved by 38% than the previous static one, allowing more margin on the variation of interconnect resistance.

A Study on the Current Status of Sizing System for Infants' & Children's Clothing (시판 유아동복 치수체계에 관한 연구)

  • Jung, Myoung Sook;Kang, Hye Jin;Jang, In Sun
    • Journal of the Korean Society of Costume
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    • v.64 no.2
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    • pp.70-83
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    • 2014
  • This study was done to provide the basic data for improving the sizing system for infants and children's clothing. The 97 brands were surveyed through market research and on-line searching. Size and body measurements were analyzed according to the content of nominal size, type of market, national and foreign brands, and meaning of reference size. The results are as follows: 1. The meaning of nominal sizes was categorized as five cases: the size based on body measurements, the size based on age, the meaningless size, letter cord and combination of 2 out of 4 cases above. The nominal size based on height was most observed, and the meaningless nominal size was second. The meaningless nominal size can cause confusion when consumer buys clothing. 2. The department stores mainly used the nominal size based on body measurements, but the Internet shopping malls largely used the meaningless nominal size. 3. Both national brands and foreign brands mainly used the nominal size based on height. But national brands largely used the different nominal sizes. 4. 41 brands indicated body measurements as reference size and 26 brands indicated product measurements as reference size. Therefore consumers tended to confuse the body measurements with the product measurement.