• Journal of Preventive Medicine and Public Health
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• v.34 no.4
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• pp.309-315
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• 2001

Objective : To develop a boner understanding of the relationship between weight status and the prevalence of obesity related diseases in the Korean population. Methods : The 1998 Korean National Health and Nutrition Survey was used and 10,880 persons who had previously taken health examinations were selected for study. The Korean Society for the Study of Obesity's classification of weight status was used. Hypertension, diabetes mellitus, dyslipidemia, osteoarthritis, chronic heart disease, stroke were included as obesity related disease. A logistic regression model was developed to estimate the prevalence odds ratio by obesity class adjusted for demographic and socioeconomic factors and we converted the odds ratio to a prevalence ratio using the base line prevalence of disease to aid in the interpretation of the ratios. Results : The prevalence of obesity was 26.3% based on the KSSO classification $(BMI\geq25)$. A graded increase in the prevalence ratio was observed with increasing severity of overweight and obesity for all health outcomes with the exception of chronic heart disease in men and stroke in both men and women. With normal weight individuals as the reference, for men who were younger than 50 years, the prevalence ratios were highest for hypertension BMI<23-25: 1.70(95% CI=1.41-2.05), 25$BMI\geq30$: 4.83(95% CI=3.70-5.84). The prevalence ratios for dyslipidemia were as high as hypertension, but were lower than hypertension for diabetes mellitus and osteoarthritis. Prevalence ratios generally were greater in younger adults. The prevalence of having 2 or more obesity related diseases increased with weight status category, except in people who were older than 50 years. Conclusions : Based on results, obesity is an increasingly important health problem in Korea and the disease burden increases according to weight status. For Korean adults, the strongest relationship was seen between weight status and hypertension and dyslipidemia. In older people the impact of excess weight and obesity is stronger than that seen in younger people. Increased efforts in the study of obesity and prevention and treatment of obesity and obesity related disease are required.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.25 no.4
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• pp.355-363
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• 2007

The purpose of this study is to maximize the use of framework data by a method for updating road framework data using a economical, rapid, and accurate Vehicle-based kinematic survey to get the latest road data among "transportation framework data" which was built in 2003. We collected data using a Vehicle-based kinematic survey with DGPS (Differential Global Positioning System) in Daejeon and Pyeongtaek city and verified the accuracy of line and point features between surveying and previous results. The result showed that Daejeon city which is located near GPS CORS (Continuously Operating Reference Station)s and receive a signal well had lower errors than 1/5,000 digital base map, and Pyeongtaek city which is located far from the stations and receive a signal badly had errors beyond the limits. The study showed that postprocessing method or Total Station surveying should be used where signals cannot be detected well after analyzing a receiving rate from GPS CORSs, the stations of other organizations should be shared, and further studies are needed.

• Journal of Korea Multimedia Society
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• v.11 no.4
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• pp.423-433
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• 2008

The surface curvatures extracted from the face contain the most important personal facial information. In particular, the face shape using the depth information represents personal features in detail. In this paper, we develop a method for recognizing the range face images by combining the multiple face regions using fuzzy integral. For the proposed approach, the first step tries to find the nose tip that has a protrusion shape on the face from the extracted face area and has to take into consideration of the orientated frontal posture to normalize. Multiple areas are extracted by the depth threshold values from reference point, nose tip. And then, we calculate the curvature features: principal curvature, gaussian curvature, and mean curvature for each region. The second step of approach concerns the application of eigenface and Linear Discriminant Analysis(LDA) method to reduce the dimension and classify. In the last step, the aggregation of the individual classifiers using the fuzzy integral is explained for each region. In the experimental results, using the depth threshold value 40 (DT40) show the highest recognition rate among the regions, and the maximum curvature achieves 98% recognition rate, incase of fuzzy integral.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.6
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• pp.2941-2946
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• 2016

Background: The limitations of total serum PSA values remain problematic, especially after an initial negative prostate biopsy. In this prospective study of Chilean men with a continued suspicion of prostate cancer due to a persistently elevated total serum PSA, abnormal digital rectal examination and initial negative prostate biopsy were compared with the use of the on-line Chun nomagram, detection of primary malignant circulating prostate cells (CPCs) and free percent PSA to predict a positive second prostate biopsy. We hypothesized that men negative for circulating prostate cells have a small risk of clinically significant prostate cancer and thus may be conservatively observed. Men positive for circulating prostate cells should undergo biopsy to confirm prostate cancer. Materials and Methods: Consecutive men with a continued suspicion of prostate cancer underwent 12 core TRUS prostate biopsy; age, total serum PSA and percentage free PSA and Chun nomagram scores were registered. Immediately before biopsy an 8ml blood simple was taken to detect primary mCPCs. Mononuclear cells were obtained by differential gel centrifugation and identified using double immunostaining with anti-PSA and anti-P504S. Biopsies were classifed as cancer/no-cancer, mCPC detecton test as negative/positive and the total number of cells/8ml registered. Areas under the curve (AUC) for percentage free PSA, Chun score and CPCs were calculated and compared. Diagnostic yields were calculated with reference to the number of possible biopsies that could be avoided and the number of clinically significant cancers that would be missed. Results: A total of 164 men underwent a second biopsy; 41 (25%) had cancer; the AUCs were 0.65 for free PSA, 0.76 for the Chun score and 0.87 for CPC detection, the last having a significantly superior prediction value (p=0.01). Using cut off values of free PSA <10%, Chun score >50% and ${\geq}1$ CPC detected, CPC detection had a higher diagnostic yield. Some 4/41 cancers complied with the criteria for active surveillance, free PSA and the Chun score missed a higher number of significant cancers when compared with CPC detection. Conclusions: Primary CPC detection outperformed the use of free PSA and the Chun nomagram in predicting clinically significant prostate cancer at repeat prostate biopsy.

• Korean Journal of Remote Sensing
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• v.11 no.3
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• pp.33-47
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• 1995

The representation of point-observed environmental variables in Geographic Information Systems(GIS) has often been inadequate to meet the need of regional-scale ecological and environmental applications. To create a map of continuous surface that would represent more reliable spatial variations for these applications, I present three spatial estimation methods. Using a secondary variable of the proximity to coast line together with rainfall acidity data collected at the 63 acid rain monitoring stations in Korea, average rainfall acidity map was cteated using co-kriging. For comparison, two other commonly used interpolation methods (inverse distance weighting and kriging) were also applied to rainfall acidity data without reference to the secondary variable. These estimation methods were evaluated by both visual assessments of the output maps and the quantitative comparison of error measures that were obtained from cross validation. The co-kriging method produced a rainfall acidity map that showed noticeable improvement in repoducing the inherent spatial pattern as well as provided lower statistical error as compared to the methods using only the primary variable.

• Journal of Periodontal and Implant Science
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• v.49 no.5
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• pp.299-309
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• 2019

Purpose: To analyze the ridge profile of the anterior maxilla using cone-beam computed tomography and to assess the clinical significance of the ridge profile by performing virtual implant placement. Methods: Thirty-two cone-beam computed tomography scans of anterior maxillae were included. For each tooth, a vertical line was made along the longitudinal axis, and 3 horizontal lines at 1-, 3-, and 5-mm levels below the labial bone crest were drawn perpendicularly to the vertical reference. At these levels, the thickness of the alveolar ridge (RT), and the labial (LT) and palatal bone plate (PT) were measured. Then, virtual implant placement using standard and tapered implants was performed. A generalized linear mixed model was used for statistical analysis. Results: The teeth were located labially based on the proportion of LT and PT with respect to RT. At the 1-mm level, the value of LT was between $1.0{\pm}0.4mm$ for central incisors and $1.3{\pm}0.6mm$ for canines. A large number of teeth had area(s) with less than 1-mm-thick labial bone between the 1- and 5-mm levels below the crest. The mean PT was generally thicker than the LT in all tooth types. The greatest mean value of labial concavity was observed for canines, compared to other tooth types. Men had a greater RT than did women, but had a comparable LT. Less apical fenestration was observed when tapered implants were used. Conclusions: Most teeth in the anterior maxilla had a thin labial bone plate, with no significant difference between sexes. Tapered implants may be advantageous for the anterior maxilla.

• YAKHAK HOEJI
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• v.52 no.3
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• pp.188-194
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• 2008

Fexofenadine, ($\pm$)-4-1-hydroxy-4-{4-(hydroxydiphenylmethyl)-1-piperidinyl}-butyl-a,a-dimethyl benzeneacetic acid, is a selective histamine $H_1$ receptor antagonist, and is clinically effective in the treatment of seasonal allergic rhinitis and chronic idiopathic urticaria as a first-line therapeutic agent. The purpose of the present study was to evaluate the bioequivalence of two fexofenadine hydrochloride tablets, $Allegra^{(R)}$ (Handok Pharmaceuticals Co., Ltd.) and Alecort (Samchundang Pharmaceutical Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The release of fexofenadine from the two fexofenadine hydrochloride formulations in vitro was tested using KP VIII Apparatus II method with various dissolution media. Twenty six healthy male subjects, 25.62$\pm$3.35 years in age and 70.05$\pm$11.71 kg in body weight, were divided into two groups and a randomized 2$\times$2 cross-over study was employed. After a single tablet containing 120 mg as fexofenadine hydrochloride was orally administered, blood samples were taken at predetermined time intervals and the concentrations of fexofenadine in serum were determined using HPLC with fluorescence detector. The dissolution profiles of two formulations were similar in all tested dissolution media. The harmacokinetic parameters such as $AUC_t$, $C_{max}$ and $T_{max}$ were calculated, and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t$, $C_{max}$ and untransformed $T_{max}$. The results showed that the differences between two formulations based on the reference drug, $Allegra^{(R)}$, were -1.37, 5.22 and 16.50% for $AUC_t$, $C_{max}$ and $T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 (e.g., log 0.83$\sim$log 1.08 and log 0.81$\sim$log 1.03 for $AUC_t$ and $C_{max}$, respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Alecort tablet was bioequivalent to $Allegra^{(R)}$ tablet.

• The Journal of the Korean dental association
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• v.56 no.12
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• pp.695-706
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• 2018

Objectives: The purpose of this study was to investigate the ratio of 4 root canals and the incidence of Radix Entomolaris in mandibular first molars and find out anatomical difference according to number of roots by analysis of cone-beam CT images in a Korean population. Materials and Methods: Total 142 images containing mandibular first molars were selected from CBCT images taken from 2013 to 2017 at Gangneung-Wonju National University Dental Hospital. After reconstructing the image with reference to the Cemento-enamel junction, the root canals were detected at the bottom of the pulpal floor and the number of roots and root canals were analyzed. Various lengths and MLO-DLO-DBO angle were measured between each canal orifices and the external contour line of the tooth, and the distolingual canal wall thickness was measured. Student t-test was used for statistical significance. Results: Among the total 142 teeth, 4 canals were 42.2% and Radix Entomolaris was 25.3%. As the results of measuring various lengths and the angle, the distolingual canal orifice in Group 2(with Radix Entomolaris) tends to deviate to the lingual side than the mesiolingual canal orifice and to the mesial side than the distobuccal canal orifice. Besides, thickness of the distolingual canal wall in Group 2(with Radix Entomolaris) was significantly thinner than that of Group 1 at every level except pulpal floor level. Conclusion: It is necessary to consider the difference according to the presence of Radix Entomolaris in endodontic treatment.

• Korean Journal of Remote Sensing
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• v.35 no.2
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• pp.203-215
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• 2019

As hyperspectral sensors that can be mounted on drones are developed, it is possible to acquire hyperspectral imagery with high spatial and spectral resolution. Although the importance of atmospheric correction has been reduced since imagery of drones were acquired at a low altitude,studies on the conversion process from raw data to spectral reflectance should be done for studies such as estimating the concentration of surface materials using hyperspectral imagery. In this study, a vicarious radiometric calibration and an atmospheric correction algorithm based on atmospheric radiation transfer model were applied to hyperspectral data of drone and the results were compared and analyzed. The vicarious calibration method was applied to an empirical line calibration using the spectral reflectance of a tarp made of uniform material. The atmospheric correction algorithm used ATCOR-4 based Modran-5 that was widely used for the atmospheric correction of aerial hyperspectral imagery. As a result of analyzing the RMSE of the difference between the reference reflectance and the correction, the vicarious calibration using the tarp in a single period of hyperspectral image was the most accurate, but the atmospheric correction was possible according to the application purpose of using hyperspectral imagery. If the correction process of normalized spectral reflectance is carried out through the additional vicarious calibration for imagery from multiple periods in the future, accurate analysis using hyperspectral drone imagery will be possible.

• Journal of Korean Tunnelling and Underground Space Association
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• v.23 no.5
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• pp.339-357
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• 2021

As the construction of trans infrastructure using the underground tunnel have been rapidly increased, various nearby excavation of existed underground facility including subway structure has been occurred in urban tunnelling. The concern and worry relating to the safety and stability of the existed facility by nearby excavation is becoming the key issues in urban tunnelling. In this study, it was conducted for existed the subway station structure at Seoul subway line which was closely located in the new Dongbuk urban metro railway to determine the behavior characteristics of station structure according to adjacent tunnel construction. Also, it was reviewed the evaluation of the safety zone and excavation method for subway structure. And after a review of damage evaluation, track irregularities and structural calculation by using a numerical analysis, stability of the subway structure according to nearby tunnel excavation was evaluated to be secured. This study is expected to be applied as useful reference in advance if you need to review the effects of existed structure according to nearby construction in complex urban tunnelling.