• Title/Summary/Keyword: reduction of damage

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Occurrence and Influence of acid Leachate by Pyrite in Underground Rocks of Road Construction Field in the Miryang Area (밀양지역 도로건설 현장 지반암석내 분포하는 황철석에 의한 산성침출수 발생과 영향)

  • Chae, Sun Hee;Jeong, Chan Ho;Lee, Yu Jin;Lee, Yong Cheon;Shin, Sang Sik;Park, Jun Sik;Ou, Song Min
    • The Journal of Engineering Geology
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    • v.28 no.3
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    • pp.501-512
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    • 2018
  • The acid leachate derived from the sulfide mineral such as pyrite can cause problems such as aging of infrastructure and environment contamination around the civil construction site. The purpose of this study is to assess the environmental effect of an acid leachate derived from pyrite in the Miryang area under road construction. In this study, 13 samples of situ core were used for the net acid generation (NAG) experiment. The chemical composition including pH, oxidation and reduction potential (ORP) and electrical conductance of water samples produced from the NAG test was analyzed. In additional, five polished thin sections of rock cores were made for electro microprobe analyses. In the results of the NAG tests, 7 samples showed lower values than pH 3.5. It strongly indicated that these areas are under the environmental and infrastructure damage by the acid leachate. The chemical type of the 7 samples was classified as the $Fe(Ca)-SO_4$ type, which is totally a different type compared to general groundwater. The concentration of total sulfur ranges from 0.004% to 12.5%. 6 rock samples are plotted on a potentially acid forming zone in the relation diagram between the total sulfide and NAG-pH. In conclusion, it is suggested that a protection method against an environmental demage and an infrastructure corrosions by the acid leachate should be prepared in all of areas under a road construction.

Evaluation of Phototoxicity for Cosmetics and Alternative Method (화장품 광독성 평가와 동물대체시험법)

  • Lee, Jong-Kwon;Sin, Ji-Soon;Kim, Jin-Ho;Eom, Jun-Ho;Kim, Hyung-Soo;Park, Kui-Lea
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.31 no.3 s.52
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    • pp.245-251
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    • 2005
  • Safety is one of the key issue in the regulation of cosmetics. Cosmetic Act deals with it in Korea. The guidance for the testing cosmetic ingredients and their safety evaluation are prepared by Korea Food and Drug Administration. Ultraviolet radiation could Induce skin damage, edema, erythema, photoaging, immune dysfunction and skin cancer. Ultraviolet radiation is classified as Group 2A(probably carcinogenic to humans) by International Agenry for Reaserch on Cancer(IARC). The in vitro methodologies for evaluating the toxic potential of ingredients reported in the literature have not yet been sufficiently validated for use in areas other than the study for mutagenicity/genotoxicity, for pre-screening for severe irritancy, for screening of phototoxicity and for evaluating the percutaneous absorption. The 3T3 neutral red uptake photoxicity test (3T3 NRU PT) was accepted as OECD toxicity guideline in 2002. The 3T3 NRU PT is an in vitro method based on a comparison of the cytotoxicitv of a chemical when tested in the presence and in the absence of exposure to a non-cytotoxic dose of UVA/visible light.

Effect of Ramaria botrytis Methanol Extract on Hepatotoxicity in Benzo(α) Pyrene-treated Mice and Expression of Cytochrome P-450 1A1 Isozyme (벤조피렌 유발 마우스에서 싸리버섯 메탄올 추출물의 간 독성 억제효과 및 사이토크롬 P-450 1A1 Isozyme의 발현에 미치는 영향)

  • Kim, Hyun-Jeong;Lee, In-Seon;Bae, Jun-Tae;Kim, Ok-Mi;Park, Sun-Hee;Chang, Jong-Sun;Park, Jun-Hong;Lee, Kap-Rang
    • The Korean Journal of Mycology
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    • v.31 no.1
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    • pp.34-39
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    • 2003
  • This study was conducted to investigate effects of Ramaria botrytis methanol extract on liver damage in benzo$({\alpha})$pyrene(B$({\alpha})$P)-treated mice. The activities of serum amminotransferase, cytochrome P-450, aminopyrine N-demethylase, aniline hydroxylase and hepatic content of lipid peroxide after B$({\alpha})$P-treatment were increased than control, but those levels were significantly decreased by the treatment of Ramaria botrytis methanol extract. Whereas, the hepatic glutathione content and activities of glutathionie S-transferase and r-glutamylcysteine syntherase were increased by the treatment of Ramaria botrytis methanol extract. In addition, cytochrome P-450 1A1 izozyme protein level, remarkably increased by B$({\alpha})$P-treatment was decreased by the treatment with methanol extract of Ramaria botrytis. These results suggest that the protective effect of methanol extract of Ramaria botrytis on liver injury in B$({\alpha})$P-treated mice may be due to reduction of oxygen free radical.

Effect of Plant Growth Regulators on Minimizing Ozone Injury in Tobacco(Nicotiana tabacum L.) (식물생장조절제(植物生長調節劑) 처리(處理)가 담배의 오존 피해경감(被害輕減)에 미치는 영향(影響))

  • Park, K.S.;Cho, J.H.;Sohn, J.K.;Lee, S.C.
    • Korean Journal of Weed Science
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    • v.18 no.1
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    • pp.54-62
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    • 1998
  • This experiment was conducted to find out the effects of ABA and IAA on activities of antioxidant enzymes, antioxidant content, and growth of tobacco under exposure to ozone. The exposure to ozone in tobacco plant significantly decreased plant height, but it did not show any difference in vegetative characteristics except plant height of IAA $10^{-3}$M treated. Total chlorophyll content of NC 82 was dramatically decreased with increase in days after ozone treatment. However, reduction of chlorophyll was minimized when plant growth regulators were treated before ozone exposure. Three days treament of ozone in tobacco increased ascorbic acid of oxidised form, while slightly decreased `in reduced ascorbic acid by IAA treatment. But seven days of ozone treatment showed increase in ascorbic acid and decrease in dehydroascorbic acid. Ozone treatment did not show any difference in glutathione content and glutathione reductase activity when plant growth regulators were treated. Activities of superoxide dismutase(SOD), ascorbate peroxidase(AP) and guaiacol peroxidase(GP) were increased by the exposure to ozone for three days. However, there were no difference in activities of SOD, AP and GP due to exposure to ozone for seven days. These reactions may be interpreted as protective responses to prevent or alleviate the damage of tobacco plant by ozone exposure.

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Electrical Characteristics of PV Modules with Odd Strings by Arrangement on Bypass Diode (홀수스트링 PV모듈의 바이패스 다이오드 배치에 의한 전기적 특성)

  • Shin, Woo-Gyun;Go, Seok-Hwan;Ju, Young-Chul;Song, Hyung-Jun;Kang, Gi-Hwan
    • Journal of the Korean Solar Energy Society
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    • v.37 no.4
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    • pp.1-11
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    • 2017
  • Most PV modules are fabricated by 6 cell-strings with solar cells connected in series. Moreover, bypass diodes are generally installed every 2 cell-strings to prevent PV modules from a damage induced by current mismatch or partial shading. But, in the case of special purpose PV module, like as BIPV (Building Integrated Photovoltaic), the number of cell-strings per module varies according to its size. Differ from a module employing even cell-strings, the configuration of bypass diode should be optimized in the PV module with odd strings because of oppositely facing electrodes. Hence, in this study, electrical characteristics of special purposed PV module with odd string was empirically and theoretically studied depending on arrangement of bypass diode. Here, we assumed that PV module has 3 strings and the number of bypass diodes in the system varies from 2 to 6. In case of 2 bypass diodes, shading on a center string increases short circuit current of the module, because of a parallel circuit induced by 2 bypass diodes connected to center string. Also, the loss is larger, as the shading area in the center string is enlarged. Thus, maximum power of the PV module with 2 bypass diode decreases by up to 59 (%) when shading area varies from 50 to 90 (%). On the other hand, In case of 3 and 6 bypass diodes, the maximum power reduction was within about 3 (W), even the shading area changes from 50 to 90 (%). As a result, It is an alternative to arrange the bypass diode by each string or one bypass diode in the PV module in order to completely bypass current in case of shading, when PV module with odd string are fabricated.

Analysis of Track-Bridge Interaction and Retrofit Design for Installation of CWR on Non-ballasted Railway Bridge (무도상 철도교 레일 장대화를 위한 궤도-교량 상호작용 해석 및 개량방안 분석)

  • Yoon, Jae Chan;Lee, Chang Jin;Jang, Seung Yup;Choi, Sang Hyun;Park, Sung Hyun;Jung, Hyuk Sang
    • Journal of The Korean Society For Urban Railway
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    • v.6 no.4
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    • pp.383-392
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    • 2018
  • This study investigated the change of additional axial stress of rail and reaction force at bridge bearings due to the track-bridge interaction when laying CWR on non-ballasted railway bridges including truss bridges with relatively long span. According to the results of the present study, additional axial stresses of rail and reaction forces at bridge bearings showed a large increase when CWR is installed on the non-ballasted railway bridge. The additional axial stress of rail can be acceptable if sufficient lateral resistance can be obtained. However, if the reaction force increases, there is a risk of damage of the bearing or pier, and therefore, it is necessary to take measures to mitigate the reaction force. It is found that additional axial stress of rail decreases when considering the frictional resistance of the bridge movable support, but its effect on the bearing reaction force is very small. On the other hand, when the longitudinal track restraint decreases, both additional axial stress of rail and bearing reaction force are reduced to a large extent. Also, when the ZLR fastening devices are applied to the region where the additional axial stress of rail is highest, bearing reaction force as well as additional axial stress of rail greatly decreased. Therefore, the application of ZLR fastening devices with the reduction of the longitudinal track restraints is very effective for installing CWR on non-ballasted railway bridges.

The Protective Effect of Zizania latifolia Extract against t-BHP-induced Oxidative Stress in HepG2 Cells (고장초 추출물의 t-BHP로 산화적 손상이 유도된 HepG2 세포 보호 효과)

  • Park, Se-Ho;Lee, Jae-Yeul;Yang, Seun-Ah;Bang, Daesuk;Jhee, Kwang-Hwan
    • Journal of Life Science
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    • v.31 no.3
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    • pp.338-345
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    • 2021
  • Zizania latifolia has long been used as a tea for both edible and medicinal purposes. However, research into the use of Z. latifolia as a high value-added edible material is lacking. In a previous study, we confirmed that tricin is the major component in Z. latifolia. In this study, we investigated the protective effect of a Z. latifolia extract (ZLE). Toxicity tests of ZLE or tricin on HepG2 cells revealed no toxicity due to ZLE or tricin at all concentrations used. The reduction in cell viability by tert-butyl hydroperoxide (t-BHP) was suppressed by treatment with ZLE or tricin. In addition, ZLE or tricin effectively inhibited the production of reactive oxygen species (generation of hydrogen peroxide, alkoxy free radicals, and peroxyl free radicals by t-BHP) and oxidative damage. ZLE or tricin treatments also increased the protein expression of superoxide dismutase 1 (SOD1), catalase, heme oxygenase-1 (HO-1), and nuclear factor erythroid-related factor 2 (Nrf2), which are known as antioxidant enzymes, suggesting that the protective effect of ZLE is related to activation of tricin. Taken together, the results indicate that Z. latifolia can be developed as a functional food material for improving liver function.

Protective Effect of Nitric Oxide against Oxidative Stress under UV-B Radiation in Maize Leaves (UV-B 조사시 옥수수 잎의 산화적 스트레스에 대한 Nitric Oxide의 보호효과)

  • Kim, Tae-Yun;Jo, Myung-Hwan;Hong, Jung-Hee
    • Journal of Environmental Science International
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    • v.19 no.12
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    • pp.1323-1334
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    • 2010
  • The effect of nitric oxide (NO) on antioxidant system and protective mechanism against oxidative stress under UV-B radiation was investigated in leaves of maize (Zea mays L.) seedlings during 3 days growth period. UV-B irradiation caused a decrease of leaf biomass including leaf length, width and weight during growth. Application of NO donor, sodium nitroprusside (SNP), significantly alleviated UV-B stress induced growth suppression. NO donor permitted the survival of more green leaf tissue preventing chlorophyll content reduction and of higher quantum yield for photosystem II than in non-treated controls under UV-B stress, suggesting that NO has protective effect on chloroplast membrane in maize leaves. Flavonoids and anthocyanin, UV-B absorbing compounds, were significantly accumulated in the maize leaves upon UV-B exposure. Moreover, the increase of these compounds was intensified in the NO treated seedlings. UV-B treatment resulted in lipid peroxidation and induced accumulation of hydrogen peroxide ($H_2O_2$) in maize leaves, while NO donor prevented UV-B induced increase in the contents of malondialdehyde (MDA) and $H_2O_2$. These results demonstrate that NO serves as antioxidant agent able to scavenge $H_2O_2$ to protect plant cells from oxidative damage. The activities of two antioxidant enzymes that scavenge reactive oxygen species, catalase (CAT) and ascorbate peroxidase (APX) in maize leaves in the presence of NO donor under UV-B stress were higher than those under UV-B stress alone. Application of 2-(4-carboxyphenyl)-4, 4, 5, 5-tetramethylimidazoline-1-oxyl-3- oxide (PTIO), a specific NO scavenger, to the maize leaves arrested NO donor mediated protective effect on leaf growth, photosynthetic pigment and free radical scavenging activity. However, PTIO had little effect on maize leaves under UV-B stress compared with that of UV-B stress alone. $N^{\omega}$-nitro-L-arginine (LNNA), an inhibitor of nitric oxide synthase (NOS), significantly increased $H_2O_2$ and MDA accumulation and decreased antioxidant enzyme activities in maize leaves under UV-B stress. This demonstrates that NOS inhibitor LNNA has opposite effects on oxidative resistance. From these results it is suggested that NO might act as a signal in activating active oxygen scavenging system that protects plants from oxidative stress induced by UV-B radiation and thus confer UV-B tolerance.

A Study on Safety Improvement of Safety Devices at Entrance of Expressway Tunnels (터널 입구부 안전시설물 안전성 증대방안 연구)

  • Lee, Jeom-Ho;Kim, Jang-Wook;Kim, Deok-Soo;Lee, Soo-Beom
    • International Journal of Highway Engineering
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    • v.10 no.4
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    • pp.235-245
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    • 2008
  • Since rapidly increase of tunnel with increasing of expressway, the study on safety improvement of safety device at entrance of expressway tunnels is necessary. The existence of tunnel occurs more speed reduction than an upward slope by itself, the collision accident of tunnel entrance causes heavier damage than that of general accident on the road. So, many kinds of safety devices such as poly-ethylene barrier, guard-rail are placed on the road side. But these devices affect the drivers as an obstacle. Although there are various safety devices that are placed at tunnel entrance, this study is related to following 2-cases. One is that the poly-ethylene barrier is placed and the other is that a safety devices is not placed. The reason that these two cases are selected, is that poly-ethylene barrier is usually placed at many tunnel entrances and safety devices can affect the drivers as an obstacle. This study is related to the difference of right-hand side clearance between inside tunnel and outside tunnel, too. The average difference observed car speed and VDS(vehicle detect system) speed nearby the tunnel is analysed. Through the statistical analysis of the average difference, this study suggests an alternatives on safety improvement of safety devices at entrance of expressway tunnels. It is concluded that the small difference of right-hand side clearance is desirable to drivers when a poly-ethylene barrier is placed. And when the difference of right-hand side clearance is large, no safety devices is desirable, and when the difference of right-hand side clearance is small, poly-ethylene barrier should be placed to improve safety.

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Acute Type V Acromioclavicular Injury Treated by the Modified Bosworth Technique (급성 제 5형 견봉쇄골관절 탈구의 치료)

  • Kim Seung-Key;Yi Sang-Hoon;Park Jong Beom;Bahk, Won-Jong;Jang Il-Seok;Chang Han
    • Clinics in Shoulder and Elbow
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    • v.2 no.2
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    • pp.126-132
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    • 1999
  • Purpose : To evaluate the functional and radiographic outcome of the modified Bosworth method in the surgical treatment of acute type V acromioclavicular joint dislocation. Materials and Methods: From June 1995 to May 1998, 20 patients were operated on for acute and complete acromioclavicular dislocation(Rockwood type V). The operative technique includes fixation of the coracoclavicular joint with Bosworth screw or 6.5mm cancellous screw and imbrication of trapezius and deltoid muscles. The average age was 34 years(range, 19 to 51 years). These 20 patients with an average follow-up of 18months, were evaluated clinically using the UCLA scoring system. Additional radiographical assessment was performed with stress radiographs. Results: Excellent or good clinical results were obtained in 95%(19 cases). And the average coracoclavicular interval ratio was decreased from 3.31(2.2-6.0) to 1.13(1-1.4) in stress radiographs. There were 4 cases of hetero­topic calcification postoperatively but there was no correlation with clinical result. Posttraumatic A-C joint arthritis was developed in one case. In that case, the distal clavicular resection was done under the arthroscopic technique. Conclusion: The severe displacement observed with type V injuries is incompatible with normal shoulder function if the shoulder is left in its displaced position. In type V injuries, significant damage to the deltoid and trapezius musculature and overlying fascia occurs, therefore open reduction and good fixation must be obtained with imbrication of trapezius and deltoid muscles. In our type V acute complete acromioclavicular dislocation, the modified Bosworth technique provides excellent results with a low complication rate.

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