• Journal of the Korean Society of Safety
• /
• v.14 no.2
• /
• pp.32-41
• /
• 1999

If the Leak-Before-Break (LBB) concept is applicable to the nuclear piping design, it is not necessary to consider the dynamic effect due to pipe rupture. Therefore, the construction cost can be significantly reduced by eliminating unnecessary pipe whip restraints and jet impingement devices. The objective of this paper is to develop the Piping Evaluation Diagram (PED) for efficient application of LBB concept to piping system at an initial piping design stage. For this purpose, the 3-D finite element analyses were performed to evaluate the crack stability. And the stress-strain curve based on the pipe material tests were used to calculate the detectable leakage crack length. Finally, the present PED which was composed as a function of NOP load and allowable SSE load, was developed for an application of LBB concept to the safety injection and shutdown cooling line in Korean Next Generation Reactor (KNGR).

• The Transactions of the Korean Institute of Electrical Engineers A
• /
• v.48 no.9
• /
• pp.1055-1063
• /
• 1999

This paper present a conceptual possibilistic approach using fuzzy set theory to manage the uncertainties in the given reliability input date of the practical power system. In this paper, an algorithm is introduced to calculate the possibilstic reliability indices according to the degree of uncertainty in the given data. The probability distribution function can be transformed into an appropriate possibilstic representation using the probability-Possibility Consistency principle(PPCP) algorithm. In this the algorithm, the transformation is performation by making a compromise between the transformation consistency and the human updating experience. Fuzzy classifcation theory is applied to reduced the number of load data. The fuzzy classification method determines the closeness of load data points by assigning them to various clusters and then determening the distance between the clusters. The IEEE-RTS with 32-generating units is used to demonstrate the capability of the proposed algorithm.

• Journal of the Korean Society for Railway
• /
• v.4 no.3
• /
• pp.110-115
• /
• 2001

Recently, many engineers actively participate in research and development w.r.t the weight reduction and the safety increase of vehicle body structure to meet the requirement of fuel economy and regulations. However, vehicle design concept related with weight reduction and safety increase is reduced to the design conflict problem. In the paper, the axial and bending collapse test of aluminum extruded beams are performed and the collapse characteristics are investigated. The analysis method to verify the fracture characteristics of aluminum extruded beam is presented and discussed.

• Journal of Korea Association of Health Promotion
• /
• v.3 no.1
• /
• pp.55-61
• /
• 2005

Functional constipation is regarded as a long-standing symptomatic manifestation of abnormal defecation expressed by either a reduced frequency of bowel movements and /or an altered act of evacuation. Patients with constipation can be treated with laxatives, diets and regular habits. Thorough evaluation of functional constipation is considered in those in whom conservative treatment with dietary advice and use of laxatives fails. Patients with normal colonic transit and normal anorectal function may only need reassurance, education and dietary advice with fiber supplementation. For constipated patients in whom such treatment modalities fail, laxatives including bulk-forming and osmotic agents may be used Although most laxatives, if used intermittently, are relatively safe, they must be chosen bearing in mind possible side effects, patient compliance and their action mechanisms. A subgroup of patients with slow transit through the colon ay be unresponsive to conventional laxatives, and, in these subjects, a trial with enteroprokinetics and sometimes stimulant laxatives should be attempted. This article presents our view of the assessment and pharmacologic treatment of functional constipation.

• Journal of Power Electronics
• /
• v.18 no.3
• /
• pp.672-680
• /
• 2018

A bidirectional exponential-gain switched-capacitor (SC) DC-DC converter is developed in this paper. When compared with existing exponential SC converters, the number of switches is significantly reduced and its structure is simplified. The voltage transfer features, voltage ripple across capacitors, efficiency and output impedance of the proposed converter are analyzed in detail. Optimization of the output impedance is also discussed and the best type of capacitance distribution is determined. A common function of the voltage gain to the output impedance is found among the proposed converter and other popular SC voltage multipliers. Experimental evaluation is carried out with a 6-24V bidirectional prototype converter.

• Journal of the Ergonomics Society of Korea
• /
• v.19 no.3
• /
• pp.51-60
• /
• 2000

Non-verbal sound feedback, called earcon, has been used for portable digital electronic products to give appropriate information for the selected function. This study evaluated usability based on user cognition time, error rate, and subjective satisfaction using 20 male and female subjects. The study compared five major user functions from a portable digital electronic product with currently available earcons and the same functions from the product with the new earcons (suggested by this study) which considered user cognitive characteristics, such as loudness, pitch, melody, and length. For subjective evaluation, the study assessed various earcons by subjective impression of sounds using the seven-point rating scales. Major statistical results indicated that the new earcons significantly reduced user error rates and generally improved user performance functions, such as 'play, off, stop, fast forward, and rewind.'

• Journal of the Korea Safety Management & Science
• /
• v.4 no.2
• /
• pp.237-249
• /
• 2002

A cutting fluid can improve machining quality and tool life by maintaining the tool toughness and by providing a lubrication effect to reduce the friction between the chip and tool interface. Although liquid nitrogen as an environmentally safe coolant has been widely recognized in cryogenic machining, its function as a lubricant is plausible due to its chemical inertness, physical volatility and low viscosity. Since a reduced friction is a direct witness of the lubrication effect from a tribological viewpoint, this paper presents an evaluation of the apparent friction coefficient on the tool-chip interface in cryogenic cutting operations to prove and characterize the lubricity of LN2 in cryogenic machining. The mathematical approaches have been formulated to derive the normal and frictional forces on the tool-chip interface for the oblique cutting tests.

• Proceedings of the SCSK Conference
• /
• 2003.09b
• /
• pp.219-238
• /
• 2003

Indole-3-acetic acid (IAA) molecule has been successfully encapsulated in biocompatible inorganic matrix in order for the cosmetic application such as superfacial fine line reduction. The encapsulation was realized through chemical reaction involving simultaneous formation of inorganic lattice and 1M giving rise to an 1M-inorganic nanohybrid (IAA-brid) which shows excellent storage stability and sustained releasing property of indole-3-acetic acid. The clinical efficacy of essence cream containing IAA-brid as anti-wrinkle formulation was also carefully evaluated by measuring the roughness of the skin replica before and after treatment. Upon administration of the cream on the eye-area, the fine-line is drastically reduced.

• Journal of the military operations research society of Korea
• /
• v.28 no.2
• /
• pp.116-124
• /
• 2002

In just-in-time production systems, U-shaped production lines rather than traditional straight lines are often adopted since they have some advantages. The advantages of U-lines over straight lines are that the workstations required can be reduced and the necessary number of workers can be easily adjusted when the demand rates are changed. In this paper, we present a new genetic algorithm(GA) to minimize the number of workstations primarily and improve the work relatedness secondarily in the U-line production systems. Also, a new heuristic method is presented according to the work related factors and characteristics of U-line balancing. Some major aspects of the proposed GA are discussed, with emphasis on representation, decoding and evaluation function. Extensive experiments are carried out on well-known test-bed problems in the literature to verify the performance of our algorithm . The computational results show that our algorithm is a promising alternative to existing heuristics.

• IMMUNE NETWORK
• /
• v.14 no.3
• /
• pp.138-148
• /
• 2014

MicroRNAs (miRNAs) are endogenous small RNA molecules best known for their function in post-transcriptional gene regulation. Immunologically, miRNA regulates the differentiation and function of immune cells and its malfunction contributes to the development of various autoimmune diseases including systemic lupus erythematosus (SLE). Over the last decade, accumulating researches provide evidence for the connection between dysregulated miRNA network and autoimmunity. Interruption of miRNA biogenesis machinery contributes to the abnormal T and B cell development and particularly a reduced suppressive function of regulatory T cells, leading to systemic autoimmune diseases. Additionally, multiple factors under autoimmune conditions interfere with miRNA generation via key miRNA processing enzymes, thus further skewing the miRNA expression profile. Indeed, several independent miRNA profiling studies reported significant differences between SLE patients and healthy controls. Despite the lack of a consistent expression pattern on individual dysregulated miRNAs in SLE among these studies, the aberrant expression of distinct groups of miRNAs causes overlapping functional outcomes including perturbed type I interferon signalling cascade, DNA hypomethylation and hyperactivation of T and B cells. The impact of specific miRNA-mediated regulation on function of major immune cells in lupus is also discussed. Although research on the clinical application of miRNAs is still immature, through an integrated approach with advances in next generation sequencing, novel tools in bioinformatics database analysis and new in vitro and in vivo models for functional evaluation, the diagnostic and therapeutic potentials of miRNAs may bring to fruition in the future.