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Status of Blood Products Release at a General Hospital in Gyeonggi-Do (경기도 일개 종합병원에서 혈액제제 출고 현황)

  • Choi, Ho-Keun;Choi, Kyung-Suk
    • Korean Journal of Clinical Laboratory Science
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    • v.54 no.1
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    • pp.73-77
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    • 2022
  • Blood products (BPs) can only be obtained through blood donation and hence represent a finite resource. BPs should therefore be used conservatively. However, BPs are being used indiscriminately without evidence. The purpose of this study was to evaluate the reasons for the use of BPs and their appropriateness. The investigation was carried out based on hemoglobin levels. Data were obtained from Nov 1, 2020, to Oct 31, 2021, from a hospital's OCS/EMR systems. The BPs were dispensed in 21,303 cases, and the number of hemoglobin levels >7.0 g/dL or higher among red blood cell drugs used by each treatment department was 1,173 (>7.0 g/dL). The misuse of blood transfusions is increasing social costs, with the adequacy of transfusion becoming increasingly important. Hence, each medical institution should review the transfusion guideline evaluation index, check the status of the release of BPs, and institute educational programs covering transfusion guidelines and continually evaluate their adequacy.

Effects of the Plasma Treatment on the Physical Property of ZnO Thin Film (플라즈마 처리가 ZnO 박막의 물리적 특성에 미치는 영향)

  • Cho, Jae-Won;Joung, Tae-Young;Rhee, Seuk-Joo
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.24 no.3
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    • pp.173-176
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    • 2011
  • The characteristic changes in ZnO thin film according to H- and O- plasma treatments have been studied by Photoluminescence (PL) spectroscopy at room temperature. The red shift of UV peak by 20-30 meV in PL spectra after plasma treatments is identified, which indicates that there are changes in the binding energy of bound exciton and/or the movement of energy levels of lattice defects and impurities. The width of UV peak is decreased after plasma treatments, which is believed to be closely related to the crystal quality of ZnO film. The increase of UV peak intensity after H-plasma treatment is also observed, and this could mean that the radiative recombination is strengthened because the hydrogen atoms in the plasma diffuse into the film where they passivate and neutralize the defects and the impurities.

Effects of Ginseng on the Formation of Glycated Protein (당화단백질의 형성에 미치는 인삼의 효과)

  • Maeng, Sung-Ho;Chun, Kang-Woong;Bae, Jin-Woo
    • Journal of Ginseng Research
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    • v.26 no.4
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    • pp.173-177
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    • 2002
  • We examined effects of red ginseng on the formation of glycated protein in vivo and in vitro. The mixtures (1 : 1 : 1, v/v/v) with glucose (1.5 g/dl, hemoglobin (10 g/d) and red ginseng extract (0.5 g/dl) in 0.067 M phosphate saline buffer were incubated for 5 days in shaking water bath (37$\^{C}$, 70 RPM). Male rats were divided into three groups with one health and two diabetes, consisting of 20 heads in each group. Diabetic rats, induced by streptozotocin injection, were treated with or without red ginseng extract (100 mg/kg/day) for 3 months. The concentration of blood glucose and the rate of glycated hemoglobin were determined by commercial kits. The rate of glycated hemoglobin was significantly decreased by the addition of ginseng extract in comparison with non-addition group in vitro (12.17$\pm$ 1.01% vs 15.9$\pm$ 1.95%, meansd, p<0.01). Even though the levels of blood glucose in rats were not significantly different from each other, the rate of glycated hemoglobin in ginseng treated diabetic rats was $\pm$ se significantly lower than non-treated diabetic rats after 3 months (15.1$\pm$ 2.06% vs 20.1 $\pm$ 2.9%, mean$\pm$ sd, p<0.05). Additionally, the body weight was increased, drinking water volume was decreased non-significantly by the treatment of ginseng extract. These results suggest that ginseng can also inhibit the formation of glycated protein by other mechanisms which are not related with hyoglyemic effect of ginseng.

Measurement of Cell Death Constant in Anabaena flos-aquae (Cyanophyceae) by the Molecular Probe (Anabaena flos-aquae 에서의 세포사멸계수(Cell Death Constant)의 측정)

  • 오인혜
    • The Korean Journal of Ecology
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    • v.20 no.3
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    • pp.169-173
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    • 1997
  • The measurement of cell death constant in Anabaena flos-aquae was tested by the Live/Dead BacLight Viability kit(Molecular Probes Co., Seatle, WA). When the Live/Dead BacLight Viability kit was applied to Anabaena flos-aquae, the cells with intact cell membranes(live cells) stained fluorescent green, while the cell with damaged membranes(dead cells) stained fluorescent red and the background remained virtually nonfluorescent. The rations of live : dead cells in the cell suspension were controlled artifically and Live/Dead BacLight Viability kit was applied to them. The ratios of green:red fluorescent cells in the cell suspension were the same as those of live : dead cells controlled artifically. It was also approved by the fluorescence emission. The cell death constant was measured in the P-limited Anabaena flos-aquae chemostal culture in the N-fixing and $KNO_3-supplied$ conditions. The culture in N-fixing chemostat had a dead cell proportion of 1.2% at the growth rate of 0.7/day and increased to 2.6% at the growth rate of 0.3/day. The cell death constant of N-fixing culture was 0.008/day.There was a same trend in the $KNO_3-supplied$ chemostat culture. The proportion of dead cell was 1.6% of dead cell proportion at the growth rate of 0.7/day and increased to 4.3% at the growth rate of 0.3/day.

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Comparative Study on the Color Stability of Temporary Prosthetic Materials for Dental CAD-CAM (치과 CAD-CAM용 임시 수복재의 색 안정성 비교 연구)

  • Lee, Hye-Eun;Kim, Won-Soo;Kim, Jung-suk;Lee, Ju-hee;Won, Seuck-Jae
    • Journal of Technologic Dentistry
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    • v.38 no.3
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    • pp.165-173
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    • 2016
  • Purpose: This study was conducted to examine the color stability of temporary prosthetic materials for dental CAD-CAM. Method: 2 kinds of existing acrylic resin temporary filling materials and 2 kinds of polymer prosthetic materials for dental CAD-CAM were used for testing, and five specimens respectively were absorbed in soy sauce, red pepper paste, and coffee. A Chroma Meter was used as analysis equipment. The color change of the specimens was observed to calculate ${\Delta}E$ value throughout 2 days, 3 days, 4 days, and 5 days and this was analyzed and the following result was obtained. Results: Snap's ${\Delta}E$ value was bigger than Vipi block(p<0.05). Red pepper paste had the largest impact on the color change of resin(${\Delta}E$), followed by soy sauce and coffee(p<0.000). With the passage of time, ${\Delta}E$ value was inversely(-) related and decreased somewhat(p<0.000).

Self Esteem and Career Identity of Nursing Students (간호대학 학생들의 자아존중감 및 진로정체감에 관한 연구)

  • Cho, Hee;Lee, Gue-Young
    • Journal of Korean Public Health Nursing
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    • v.20 no.2
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    • pp.163-173
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    • 2006
  • Purpose: This is a descriptive study to identify the self esteem and career identity of nursing students. Method: The sample consisted of 416 junior nursing students of diploma programs in the cities of Seoul and Kyung-gi area, and Kyungbook province. Data were analyzed by the program of SPSS WIN 11.5. Results: Self esteem was significantly higher in the students attending rural school than in those attending urban school (F=3.46, p<.03), in those between the age of 24-25 years than in the rest (F=2,17, p<.05), and in those satisfied on admission to nursing school than in those less satisfied (F=3.12 p<.04). Career identity was significantly higher in the students between the age of 24-25 years than in the rest (F=6.10, p<.000), and in those satisfied on admission to nursing school than in those less satisfied (F=49.64, p<.000). The results of correlational analysis between self esteem and career identity revealed that career identity increased with increasing self esteem(r=.316 p<.001). Conclusion: Based on the above findings, programs are needed for the improvement of self esteem and career identity, and further research is suggested on the development of such programs.

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Effects of Inoculation with Phosphate-Solubilizing Microorganisms on Availability and Plant Uptake of Phosphorus in Red-yellow and Calcareous Soils of Korea (한국(韓國)의 적황색(赤黃色) 및 석회질토양(石灰質土壤)에서 인산(燐酸)의 유효화(有效化) 및 작물(作物)의 인산흡수(燐酸吸收)에 대한 인산염(燐酸鹽) 가용화균(可溶化菌) 접종(接種) 효과(效果))

  • Suh, Jang-Sun;Kim, Kwang-Sik
    • Korean Journal of Soil Science and Fertilizer
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    • v.29 no.2
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    • pp.173-180
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    • 1996
  • Effects of inoculation with phosphate-solubilizing microorganisms, Pseudomonas putida and Aspergillus niger, were studied in both acidic red-yellow and alkaline calcareous soils cropped with pimiento. In red-yellow soil after cultivation, the amounts of soil available phosphorus on non-fertilizer and fertilizer plots inoculated with Aspergillus niger, and on rice straw plot inoculated with Pseudomonas putida and Aspergillus niger were significantly higher than uninoculation treatments, but there were no differences in calcareous soil. With inoculation of either Pseudomonas putida or Aspergillus niger, increase in phosphorous uptake by pimiento cultivated in calcareous soil was detected on non-fertilizer, and fertilizer plots except rice straw plot. Although there were no significant differences in soil cellulase activities among treatments, the activity was the highest on rice straw plot in red-yellow soil. The phosphatase activities in red-yellow soil were increased by the inoculation with Aspergillus niger only, and the activity in calcareous soil was improved by the inoculation with either Pseudomonas putida or Aspergillus niger.

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Recent Advances in Studies on Chemical Constituents and Biological Activities of Korean Black Ginseng(Panax ginseng C. A. Meyer) (흑삼의 화학성분 및 생리활성에 대한 최근 연구)

  • Nam, Ki Yeul;Kim, Yeong Su;Shon, Mi Yae;Park, Jong Dae
    • Korean Journal of Pharmacognosy
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    • v.46 no.3
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    • pp.173-188
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    • 2015
  • We have conducted a comprehensive literature review regarding the chemical constituents and biological activities of Korean black ginseng(Panax ginseng C. A. Meyer), three to nine times-steamed and dried ginseng, which shows strong black color through Maillared browning reaction. It has been reported that some chemically deglycosylated and transformed saponins are obtained from black ginseng as artifacts produced during intensive steaming. They have been known to be ginsenosides Rg3, Rg4, Rg5, Rg6, Rh1, Rh2, Rh4, Rk1 and Rk3, quite different from those of red ginseng, among which ginsenosides Rg3, Rg5 and Rk1 are considered to be major components. And also, black ginseng has been recently found to demonstrate anticancer, recovery from learning and memory damages, hypontensive, antidiabetic, antiobesitic, tonic and antiatopic activities, together with antioxidative and exercise performance improving activities, exhibiting their effects to be a little bit stronger than those of red ginseng. These findings suggest that black ginsng might play an important role in the development of promising functional foods and drugs from the viewpoint of the chemical composition and biological activities of black ginseng with a distinction from those of white and red ginsengs. In this review, the authors will survey and evaluate further functions of black ginseng with a focus on its physicochemical properties and biological activities.

Bioactive Components from Red Tide Plankton, Cochlodinium polykrikoides (Cochlodinium polykrikoides 적조 조체의 생리활성 성분)

  • LEE Jong-Soo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.29 no.2
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    • pp.165-173
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    • 1996
  • Large amounts (300 grams) of natural red tide plankton, Cochlodinium polykrikoides, was collected at the Yokji island coastal waters, Kyeongnam, Korea, on October, 1993. Using the bioassay systems, bioactive materials were screened from methanol extracts of C. polykrikoides. Live C. polykrykoides was toxic to fishes, however, the water soluble and chloroform soluble fraction of their methanol extracts did not shown ichthyotoxicity (5 mg/ml), and toxicity to mice (50 mg, i.p,). These fractions did not show any peaks corresponding to paralytic shellfish toxins or diarryhetic shellfish toxins on the fluorometric HPIC chromatograms. Neither fractions did not show antibiotic activities by paper disk (10 mg/disc) test and chloroform soluble fraction showed only $20\%$ growth inhibition activity on the Lymphoid P-388 at the concentration of $180\;{\mu}g/ml$. Hemolytic activity was detected by both fractions. Fatty acid analysis by GC, GC/MS and proton NMR showed that the chloroform soluble fraction composed of $25.3\%$ of DHA (dorosahexaenoic acid) and $15.3\%$ of IPA (eicosapentaenoic acid) as the hemolytic components.

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Highly Efficient Red Emissive Heteroleptic Cyclometalated Iridium(III) Complexes Bearing Two Substituted 2-Phenylquinoxaline and One 2-Pyrazinecarboxylic Acid

  • Sengottuvelan, Nallathambi;Yun, Seong-Jae;Kim, Dae-Young;Hwang, In-Hye;Kang, Sung Kwon;Kim, Young-Inn
    • Bulletin of the Korean Chemical Society
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    • v.34 no.1
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    • pp.167-173
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    • 2013
  • A series of highly efficient red phosphorescent heteroleptic iridium(III) complexes 1-6 containing two cyclometalating 2-(2,4-substitued phenyl)quinoxaline ligands and one chromophoric ancillary ligand were synthesized: (pqx)$_2Ir$(mprz) (1), (dmpqx)$_2Ir$(mprz) (2), (dfpqx)$_2Ir$(mprz) (3), (pqx)$_2Ir$(prz) (4), (dmpqx)$_2Ir$(prz) (5), (dfpqx)$_2Ir$(prz) (6), where pqx = 2-phenylquinoxaline, dfpqx = 2-(2,4-diflourophenyl)quinoxaline, dmpqx = 2-(2,4-dimethoxyphenyl)quinoxaline, prz = 2-pyrazinecarboxylate and mprz = 5-methyl-2-pyrazinecarboxylate. The absorption, emission, electrochemical and thermal properties of the complexes were evaluated for potential applications to organic light-emitting diodes (OLEDs). The structure of complex 2 was also determined by single-crystal X-ray diffraction analysis. Complex 2 exhibited distorted octahedral geometry around the iridium metal ion, for which 2-(2,4-dimethoxyphenyl)quinoxaline N atoms and C atoms of orthometalated phenyl groups are located at the mutual trans and cis-positions, respectively. The emission spectra of the complexes are governed largely by the nature of the cyclometalating ligand, and the phosphorescent peak wavelengths can be tuned from 588 to 630 nm with high quantum efficiencies of 0.64 to 0.86. Cyclic voltammetry revealed irreversible metal-centered oxidation with potentials in the range of 1.16 to 1.89 V as well as two quasi-reversible reduction waves with potentials ranging from -0.94 to -1.54 V due to the sequential addition of two electrons to the more electron-accepting heterocyclic portion of two distinctive cyclometalated C^N ligands.