• 제목/요약/키워드: recording period

검색결과 244건 처리시간 0.159초

정상 망막과 변성 망막을 위한 전기자극 파라미터 (Electrical Stimulation Parameters in Normal and Degenerate Rabbit Retina)

  • 진계환;구용숙
    • 한국의학물리학회지:의학물리
    • /
    • 제19권1호
    • /
    • pp.73-79
    • /
    • 2008
  • 망막색소변성(retinitis pigmentosa: RP)과 연령 관련 황반변성(age-related Macular Degeneration: AMD)은 망막변성으로 인해 실명에 이르는 대표적인 질환이며 망막이식장치의 개발을 통해 치료될 수 있다고 간주되고 있다. 최근에 국내에서도 망막이식장치 개발을 위한 연구팀이 조직되었다. 성공적인 망막이식장치 개발을 위하여 여러 가지 선결요소가 필요하지만 그 중 한 가지가 이식장치에 인가할 전기자극을 최적화하는 것이다. 변성망막의 전기적 특성은 정상 망막과 다르리라 예측되므로 우리는 장차 개발될 망막 이식장치에 인가할 전기자극 최적화를 위한 가이드라인을 제공하기 위해 정상 망막과 변성 망막의 전압자극 파라미터에 관한 실험을 하였다 망막을 분리한 후 망막절편을 신경절세포 층이 다채널전극의 표면을 향하게 하여 전극에 붙인다 in-vitro 상태에서 망막 신경절세포의 전기신호를 기록하기 위해 전극 직경: $30{\mu}m$, 전극간 거리: $200{\mu}s$, 전극 임피던스 1kHz 에서 $50k{\Omega}$인 8행 8열의 다채널전극을 사용하였다. 다채널전극의 60채널 중 두 채널을 자극전극과 접지로 사용하여 단극전기자극을 인가하였고 나머지 전극을 기록전극으로 사용하였다. 가한 전기자극은 전압자극으로 전하균형을 맞춘 이상성자극을 아노딕 사각파를 먼저 주고 캐쏘딕 사각파가 나중에 나오는 형태로 두 사각파간의 지체는 없도록 하였으며 동일한 자극을 2초 간격으로 50회 반복하여 인가하였다. 다양한 전기자극을 사용하였는 바 첫째는 사각파의 크기를 달리하였다 $(0.5{\sim}3V)$. 둘째는 사각파의 시간을 달리하였다 $(100{\sim}1,200{\mu}s)$. 전하밀도는 옴의 법칙과 쿨롱의 법칙을 이용하여 계산하였다. 전기자극으로 유발된 반응은 50회 자극에 대한 평균치를 얻은 후 자극 후 히스토그램(PSTH)을 그려 분석하였다. 전압자극의 크기를 $0.5{\mu}3V$로 달리하였을 때 믿을 만한 망막신경절세포가 유발되는 자극은 1.5V이었고 이때 계산된 전하밀도의 역치는 $2.123mC/cm^2$이었다. 전압의 크기를 2V로 고정하고 자극 지속시간을 $100{\sim}1,200{\mu}s$로 달리하였을 때 믿을 만한 망막신경절세포가 유발되는 자극의 역치는 $300{\mu}s$에서 관찰되었다. 이때 계산된 전하밀도의 역치는 $1.698mC/cm^2$이었다. L-(1)-2-amino-4-phosphonobutyric acid (APB)을 사용하여 ON-경로를 차단한 후에 전기자극을 인가하였을 때도 자극에 의해 망막신경절 세포의 반응이 유발되는 것을 확인하였다. APB-변성망막에서 전압의 크기를 2V로 고정하고 자극 지속시간을 $100{\sim}1,200{\mu}s$로 달리하였을 때 믿을 만한 망막신경절세포가 유발되는 자극의 역치는 $300{\mu}s$에서 관찰되었으며 이는 정상망막의 결과와 같았다. 추후 APB-변성망막을 가지고 좀더 실험이 진행되어야 정상망막과 변성망막의 전하밀도에 관한 명료한 비교가 가능할 것이다.

  • PDF

도심지 열대야 및 빛공해에 의한 매미 울음 영향 (Effects of Tropical Night and Light Pollution on Cicadas Calls in Urban Areas)

  • 기경석;김지연;윤기상;이재윤
    • 한국환경생태학회지
    • /
    • 제30권4호
    • /
    • pp.724-729
    • /
    • 2016
  • 지금까지 매미 울음에 영향을 미치는 환경요인에 관한 연구는 많지 않으며 특히 야간에 우는 매미에 대한 이해는 매우 부족한 상황이다. 따라서 본 연구는 도심지 열대야 및 빛 공해가 매미 울음에 영향을 미치는지 밝히는데 그 목적이 있다. 연구대상지는 서울시 서초구 아파트단지와 원주시 치악산국립공원이었다. 연구 대상종은 여름철 우점종인 참매미와 말매미를 선정하였다. 매미 울음은 7~8월 사이에 아파트단지는 25일간, 치악산은 14일간, 매일 24시간 녹음하였다. 매미 울음에 영향을 미치는 환경요인은 기온, 강수량, 습도, 일조량을 선정하였다. 통계분석은 시간당 울음, 24시간 울음, 야간 울음(21:00~04:00)의 세 가지 항목과 기상요인과의 상관관계를 분석하였다. 분석 결과 첫번째, 참매미는 아침 여명기에 울음을 시작하고 이른 아침에 울음의 피크를 이루며, 말매미는 오전과 오후에 울음의 피크를 형성하고 저녁 여명기에 울음을 멈추어 두 종간 울음 패턴의 차이가 있었다. 두 번째, 참매미는 말매미가 본격적으로 울기 시작하면 울음 빈도가 낮아져 종간 영향을 미칠 가능성이 높은 것으로 나타났다. 세 번째, 참매미와 말매미 울음과 기상요인과의 상관관계 분석결과, 두 종 모두 기온이 높을수록 많이 울고 비가 오는 날은 적게 우는 경향을 나타내었다. 네 번째, 야간으로 한정해 보았을 때, 말매미는 야간의 온도가 높을 때($24^{\circ}C{\sim}30^{\circ}C$, 평균 $27^{\circ}C$) 우는 데 반해, 참매미는 기상요인과는 상관관계를 나타내지 않았다. 그러나 참매미는 조명이 있는 지역에서만 야간에 울고 있어 빛공해가 원인으로 추정되었다.

중학교 "환경" 교과의 교수.학습 및 평가 방법 연구 (A Study on Teaching-Learning and Evaluation Methods of Environmental Studies in the Middle School)

  • 남상준
    • 한국환경교육학회지:환경교육
    • /
    • 제7권1호
    • /
    • pp.1-17
    • /
    • 1994
  • This study was performed to determine appropriate teaching-learning and evaluation methods for Environmental Studies. To promote the relevance of our study to the needs of the schools and concerned educational communities of environmental education, we reviewed related literature, conducted questionnaire surveys, interviewed related teachers and administrator, held meetings with experts, and field-tested our findings. For selecting and developing teaching-learning methods of Environmental Studies, findings of educational research in general are considered. moreover, principles of environmental education, general aim of environmental education, orientations of environmental education, and developmental stages of middle school students in educational psychology were attended. In addition, relevance to the purpose of the Environmental Studies curriculum, appropriateness for value inquiry as well as knowledge inquiry, small group centered class organization, social interaction centered teaching-learning process, regional environmental situation, significance of personal environment, evaluation methods of Environmental Studies, multi- and inter-disciplinary contents of the Environmental Studies textbook, suitability to the evaluation methods of Environmental Studies, and emphasis on the social interaction in teaching-learning process were regarded. It was learned the Environmental Studies can be taught most effectively in via of holding discussion sessions, conducting actual investigation, doing experiment-practice, doing games and plate, role-playing and carrying out simulation activities, and doing inquiry. These teaching-learning methods were field-tested and proved appropriate methods for the subject. For selecting and developing evaluation method of Environmental Studies, such principles and characteristics of Environmental Studies as objective domains stated in the Environmental Studies curriculum, diversity of teaching-learning organization, were appreciated. We categorized nine evaluation methods: the teacher may conduct questionnaire surveys, testings, interviews, non-participatory observations; they may evaluate student's experiment-practice performances, reports preparation ability, ability to establish a research project, the teacher may ask the students to conduct a self-evaluation, or reciprocal evaluation. To maximize the effect of these methods, we further developed an application system. It considered three variables, that is, evaluates, evaluation objectives domains, and evaluation agent, and showed how to choose the most appropriate methods and, when necessary, how to combine uses of different methods depending on these variables. A sample evaluation instrument made on the basis of this application system was developed and tested in the classes. The system proved effective. Pilot applications of the teaching-learning methods and evaluation method were made simultaneously; and the results and their implications are as follows. Discussion program was applied in a lesson dealing with the problems of waste disposal, in which students showed active participation and creative thinking. The evaluation method used in this lesson was a multiple-choice written test for knowledge and skills. It was shown that this evaluation method and device are effective in helping students' revision of the lesson and in stimulating their creative interpretations and responces. Pupils showed great interests in the actual investigation program, and this programme was proved to be effective in enhancing students' participation. However, it was also turned out that there must be pre-arranged plans for the objects, contents and procedures of survey if this program is to effective. In this lesson, non-participatory observation methods were used with a focus on the attitudes of students. A scaled reported in general description rather than in grade. Experiment-practice programme was adopted in a lesson for purifying contaminated water and in this lesson, instruction objectives were properly established, the teaching-learning process was clearly specified and students were highly motivated. On the other hand, however, it was difficult to control the class when some groups of students require more times to complete their experiment, and sometimes different results. As regards to evaluation, performance observation test were used for assessing skills and attitudes. If teachers use well-prepared Likert scale, evaluation of all groups within a reasonablely short period of time will be possible. The most effective and successful programme in therms of students' participation and enjoyment, was the 'ah-nah-bah-dah-market' program, which is kind of game of the flea market. For better organized program of this kind, however, are essential, In this program, students appraise their own attitudes and behavior by responding to a written questionnaire. In addition, students were asked to record any anecdotes relating to self-appraisal of changes on one's own attitudes and behaviours. Even after the lesson, students keep recording those changes on letters to herself. Role-playing and simulation game programme was applied to a case of 'NIMBY', in which students should decide where to located a refuse dumping ground. For this kind of programme to e successful, concepts and words used in the script should be appropriate for students' intellectual levels, and students should by adequately introduced into the objective and the procedures of the lessons. Written questionnaire was used to assess individual students' attitudes after the lesson, but in order to acquire information on the changes of students' attitudes and skills, pre-test may have to be made. Doing inquiry programme, in which advantages in which students actually investigated the environmental influence of the areas where school os located, had advantages in developing students' ability to study the environmental problems and to present the results of their studies. For this programme to be more efficient, areas of investigation should be clearly divided and alloted to each group so that repetition or overlap in areas of study and presentation be avoided, and complementary wok between groups bee enhanced. In this programme, teacher assessed students' knowledge and attitudes on the basis of reports prepared by each group. However, there were found some difficults in assessing students' attitudes and behaviours solely on the grounds of written report. Perhaps, using a scaled checklist assessing students' attitudes while their presentation could help to relieve the difficulties.

  • PDF

젖소 유방염 관리에 따른 세균 및 체세포수 등급 실태 조사 분석 (Analytical studies of bovine mastitis management by standard plate counts(SPC) and somatic cell counts(SCC))

  • 허정호;정명호;박영호;조명희;이주홍
    • 한국동물위생학회지
    • /
    • 제21권3호
    • /
    • pp.285-300
    • /
    • 1998
  • 1. The number of average milking cows, clinical forms of mastitis, mastitis-developing cows, and cows killed by mastitis a year were 25.7, 1.8(7%), 6.3(26%), and 2.7(10.1%)heads, respectively. The annual grade changes of standard plate counts(SPC) and somatic cell counts(SCC) showed the grade 1A of SPC diminished sharply from April to August, we think it was due to the lack of proper management in farming season and the grade 3 of SCC indirectly influenced increased in huge during August. 2. The average number of parturitions of farms was 2.3, but 50% of below 1 parturition were 22 farms(31%), 50% of above 3 parturitions were 16(23%) out of 71 farms. According to grades of the number of parturitions of milking cows per each farm, the farms' grades recording 3 parturitions and 50% were little bit excellent. 3. The actual situation research of foremilking CMT revealed 35 out of 74 farmer didn't do CMT Among them(35 out of 74 farmers), 80% did not test thanks to the troublesome process of the CMT. SCC grade 3, among farms who did foremilking CMT once or twice a month and who did not were 29% and 40% respectively and SPC grade 1A were 55% and 9%, respectively. 4. The research of actual situation on milking management let us know 29 farms(39%) did not do lastmilking, 37 farms(49%) usually did overmilking, and 34 farms(46%) did milking for 4 or 5 minutes. Grades according to average requiring times of milking showed SCC grade 1 of farms milking within 7 minutes was 11% and SPC grade 1A was 34%, on the other side, farms milking more than 7 minutes were 0% in SCC grade 1 and 13% in SPC grade 1A. Grades according to the starting time of milking after rubbing teats showed SPC grade 1A of farms starting milking at about 1 minute and over 2 minutes were 50% and 20%, respectively. 5. The research of actual situation on hygienic milking management uncovered 65 farms(88%) were using one towel which was used in washing teats and udders to wash more than 3 to 4 cows, and 53 farms(72%) were using one dried towel to dry udders not for each cow but for more than 3 to 4 cows after washing. Also, on milking turns disclosed 30 farms(40%) were milking cows in the order of incoming without isolation of a dominant group. According to grades of towels used in washing teats and udders, farms using a towel for each cow were 56% and a towel for over 3 cows were 31% in SPC grade 1A. According to using-or-not grades of dried towels after washing udders, farms using a towel for each cow were 79% and a towel for over 3 cows were 21% in SPC grade 1A. 6. Farms doing teat-dipping before milking were 7(10%), not doing teat-dipping after milking, or doing sometimes were 9(12%), and doing right after milking were 57(77%). And farms doing teat-dipping after dry cows and before delivery were 21(28a ). Farms using bethadine as an antiseptic solution were 70(95%), 40 farms(59%) diluted it with water as weak as 5 to 10 times, and on drying cows 64 farms(87%) slowly did it more than 2 days. Grade 1A of SPC of farms doing teat-dipping at every milking was 38%, farms doing occasionally or not was 33%, and farms doing it right after milking was 37% and doing after milking more than 5 cows was 20%. Grade 1A of SPC among farms diluting bethadine 5 times and diluting 5 to 10 times with water were 36% and 33%, respectively, and Grade 3 of SCC were 35% and 32%, respectively. 7. Studies on nonlactating period medical treatment, as the cows were on dry, 54 farms treated with their own hands.73 farms(98%) had bovine mastitis treated for themselves. And on applying medicines against mastitis, 55 farmers chose them on the basis of their own experience, 42 farms(57%) were treated more than 3 days. 41 farms(55%) dumped away the mastitis infected milk separately, 24 farms(32%) were feeding and milking at the same time. 8. Fifty-six farms(76%) always washed and disinfected milking machines after milking. Farms using the milking machines at low, or variable vacuum pressures, or at the vacuum pressure, set at the moment of its installation were 31(42%), and farms that did not know pulsation ratio were 27(37%). Farms changing liners when they were torn 8(11%), 58 farms(78%) said they checked milking system when there were wrong with them, 31 farms(42%) changed milking hoses when they found out problems, and 42 farms(57%) cleaned vacuum and milking systems when they felt dirty. The SPC grade 1A of farms washing and sterilizing milking machines was 38% and farms only washing was 28%.

  • PDF

한대(漢代) 이전의 의적(醫籍)을 통한 '포제(炮制)'의 연구 (A Study on processing of medicinal on medical books of before Han(漢)dynasty)

  • 김성철;하홍기;김기욱
    • 대한한의학원전학회지
    • /
    • 제24권4호
    • /
    • pp.157-174
    • /
    • 2011
  • We derived following result by organizing research about processing of medicinal of before Han(漢) dynesty. The human being intake of natural substance for the purpose of treatment was what happened later than the use of natural substance as food. According to the record of by the early years of Shang(商) dynasty, we can assume that we cooked food with water and fire. The reason why there is no appearance of common production that can be included under the name of 'Tang Ye(湯液)' in the medical record discovered from Ma Wang Dui(馬王堆) is because 'Tang Ye' was yet developed. However, as the presentation of format of medicine process, there was gradual formation of medicinal fluid concept. There are quite of records on major details of cloth manufacture like washing and selection, grinding, processing of medicine from the recordings of "Wu Shi Er Bing Fang(五十二病方)", "Yang Sheng Fang(養生方)", "Za Liao Fang(雜療方)" discovered at Ma Wang Dui. It used words like 'Ze(擇)', 'Qu(去)' for the selection and 'Jiu(酒)', 'Zhuo(濯)' for the wash as a process method before cloth manufacture. When filter the processed medicine, it used words like 'Zhuo(捉)', 'Suo(索)', 'Jun(浚)' and used 'Yin Gan(陰乾)', 'Bao(暴)', 'Yang(暘)' for dry. The 'cutting(切削)' that crushes the medicine used different names based on the properties of medicines. The most frequent crush is 'Ye(冶)' and it means the powered medicine after dry. There was thermal process of mild fire(微火) and heating of 'Wen(溫)'. There are many states of medicine seen from the medical record discovered at Ma Wang Dui so they can be said as original medicine. 藥末劑 is relatively commercialized type then. Here, it includes later 湯劑 but there was no name such as 'decoction(湯)' or 'decoction of medical ingredients(湯液)'. Also, 'Fu Ju(㕮咀)' is the transformation of what was 'Fu Qie(父且)' at "Ja Liao Fang" of medical books of Ma Wang Dui with time flow. The original meaning of 'Fu Qie(父且)' is 'Fu Zu(斧俎)' and it means the crushing medicine with axe. The most important thing among the medical books of Han dynasty is "Shen Nong Ben Cao Jing(神農本草經)" and "Shang Han Za Bing Lun(傷寒雜病論)" of Zhang Zhong Jing(張仲景). "Shen Nong Ben Cao Jing" mentioned the dry method of medicine, collection and process production time, cooked and uncooked use of medicine and there are several types of medicine. Other than those, it mentioned 'Seven methods of combining herbs(七情合和)' to address cautions for combining medicines. Therefore, the 'processing of medicinal' in east Han dynasty period entered the theoretical step. However, there is only little recording on cloth manufacture of detailed medicine. From the "Shang Han Za Bing Lun" of Zhang Zhong Jing, the development in the way of 'processing of medicinal' reveled the cloth manufacture for each medicine. This tradition is continued until today and so it presents the development of purpose of 'processing of medicinal' is to greatly present the effect of medicine and to reduce the side-effect.

한국 청소년들의 온라인 게임문화와 정체성에 관한 애니메이션 다큐멘터리 연구 (An Animated Documentary Study of Korean Youth Culture and Identity)

  • 박만기
    • 만화애니메이션 연구
    • /
    • 통권45호
    • /
    • pp.397-415
    • /
    • 2016
  • 이 소논문은 시각적 민족지학의 기반의 실습/실행 기반 연구(Practice-led Research)로써 가상공간 속 게임 캐릭터 혹은 아바타, 그리고 대규모 다중 사용자 온라인 롤플레잉 게임(MMORPGs)과 관련하여 한국 청소년들은 어떻게 자신들의 정체성과 게임 문화를 애니메이션 미디어를 통해 형성하는지 알아보는데 그 목적이 있다. 이 실습/실행기반 연구는 영국 빅토리아 시대의 로버트 루이스 스티븐슨의 소설 '지킬 앤 하이드'의 주제, 이중적 자아 정체성 혹은 정체성 혼란이라는 개념을 바탕으로 한국의 청소년들의 온라인 아바타 생성과 게임문화를 탐구한다. 이를 위한 문헌조사와 관련하여, 본인은 조심스럽게 한국의 빠른 근대화는 영국 빅토리아 시대와 평행을 이룬다고 주장한다. 예를들어, 경제적 압박과 변동 (예: 한국의 1997 IMF 사건), 그리고 그에 따른 심리적 불안과 우울증과 연관된다. 이러한 면에서, 본인의 애니메이션 실습 (애니메이션 다큐멘터리, '지킬의 레터' 2014 - 사례연구 소개)은 소설,'지킬 앤 하이드'와 실제 한국인 소년의 살인사건 사이의 연관 관계를 조사한다. 이와 관련해서 본인은 이러한 비극적 사건의 근본적인 문제들을 밝혀내기 위해 한국의 청소년들이 어떻게 온라인 게임을 그들의 일상의 삶에서 활용하는지 또한 그들의 정체성 형성에 어떠한 영향을 끼치는지를 알기위해 이와 같은 '실습/실행 기반 연구'를 구성하였다. 이는 1차적 자료를 얻기 위해 효과적이며, 이를 위해 온라인과 오프라인 조사방법을 병행한 민속지학적 접근방식을 차용하였다. 이러한 실습/실행 연구의 목적은 온라인 게임 속 유저들과 그들의 실제 삶을 비교함으로써 한국 청소년들의 문화와 정체성의 의미를 이해하며, 한국적인 특정 사례로 볼 수 있는지 알아보는 데 있다. 따라서 이 소논문에서는 한국적 특정 사례와 관련한 연구 결과에 대해 설명하기보다는 이와 같은 의문점을 답하기 위한 연구과정, 전략 그리고 애니메이션 실습 활용 방법에 대해 그 초점을 맞추려고 한다. 이를 위해 온라인과 오프라인 연구방법과 관련하여 어떻게 애니메이션 실습을 활용하는지를 4가지 성격의 애니메이션 리얼리티 혹은 다큐멘터리를 소개한다. 결국 서로 다른 성격의 애니메이션 다큐멘터리 실습방법에 의해 어떻게 한국 청소년들의 이중적 정제성과 나아가 한국적 특정사례를 효과적으로 전달하고 시각화 할 수 있는지 알아본다.

중학생의 식품 구매 행동 실태 (A Survey on Food Purchasing Behavior among Middle School Students)

  • 오미란;이혜숙;나현주;김영남
    • 한국가정과교육학회지
    • /
    • 제18권4호
    • /
    • pp.173-192
    • /
    • 2006
  • 본 연구는 청소년의 성장과 성숙 그리고 건강에 직간접으로 영향을 미칠 수 있는 식품 구매 행동에 주목하고, 청소년의 바람직한 식품 선택 및 구매를 위한 식생활 교육 프로그램 개발에 기초가 될 자료를 마련하고자 중학생 253명을 대상으로 식품 구매 행동을 파악하고, 식품을 구매할 때 고려하는 사항, 식품 구매에 미치는 광고, 친구와 부모님의 영향을 조사하였다. 연구 결과를 요약하면 다음과 같다. 첫째, 대부분의 중학생들은 식품 관련 정보를 광고와 같은 대중매체를 통해 얻고 있었으며, 용돈에서 식품 구입비가 차지하는 비율은 $20{\sim}30%$가 가장 많았다. 중학생들은 평균 $2{\sim}3$일에 1회 정도 배고픔이나 갈증을 해소하기 위해 하교 후에 집 근처 가네 또는 편의점에서 주로 과자류와 빙과류를 구매하고 있는 것으로 나타났다. 둘째, 성별, 어머니의 학력, 가정의 경제수준, 용돈 금액, 용돈 수령 주기, 용돈 사용 내역 기록 실태, 학교 소재 지역에 따라 식품 구매 행동에 있어서 차이가 나타났다.(p<.05, p<.01, p<.001). 셋째, 중학생들은 식품을 구매할 때 가격(용량)이나 맛을 가장 중요하게 생각하고 있는 것으로 나타났다. 넷째, 식품을 구매할 때 고려하는 사항들은 성별, 부모의 학력, 그리고 용돈 액수에 따라 차이가 나타났다(p<.05, p<.01, p<.001). 다섯째, 광고, 친구, 그리고 부모님이 중학생의 식품 구매에 미치는 영향을 분석한 결과, 중학생들은 식품 광고를 보면 구매 의욕이 생기고 같은 종류의 식품이라면 광고된 식품을 선택하고 스스로의 선택에 비교적 만족하는 편이지만 식품 광고의 내용을 전적으로 신뢰하거나 광고된 식품의 품질이 더욱 우수하고 생각하고 있지는 알았다. 여섯째, 성별, 어머니의 직업, 가정의 경제 수준, 그리고 용돈 액수에 따라 식품을 구매 할 때 광고, 친구, 부모님이 미치는 영향이 다르게 나타났다(p<.05, p<.01, p<.001). 이상의 인구 결과로 볼 때, 식품을 구매할 때 가격(용량)과 맛을 가장 중요하게 고려하고 주로 광고나 친구에 영향을 받는 청소년의 식품 구매 행동은 청소년의 성장, 성숙 및 건강에 지대한 부정적 영향을 미칠 수 있으므로 식품에 대한 올바른 지식의 습득을 토대로 건강 지향적인 합리적인 식품 선택 및 구매 능력을 신장시킬 수 있는 교육의 강화가 필요하다고 본다.

  • PDF

개에서 Medetomidine-Tiletamine/Zolazepam 마취에 대한 Atipamezole의 길항 효과 (The Clinical Effectiveness of Atipamezole as a Medetomidine-Tiletamine/Zolazepam Antagonist in Dogs)

  • Kwon, Young-sam;Joo, Eun-jung;Jang, Kwang-ho
    • 한국임상수의학회지
    • /
    • 제20권3호
    • /
    • pp.286-293
    • /
    • 2003
  • Medetomidine (30 ug/kg IM) - tiletamine/zolazepam (10 mg/kg IV) 합제를 사용하여 마취한 잡종견(4.00$\pm$0.53kg) 12두에서 atipamezole의 심폐계 영향과 길항효과에 대하여 평가하였다. 4개의 실험군에 각각3두씩 임의로 배당하였다 (대조군: atipamezole 처치를 하지 않은 군, A30군: atipamezole 30 um/kg, A60: atipamezole 60 ug/kg, Al50: atipamezole 150 ug/kg). 모든 실험견은 medetomidine 투여 10분 전 atropine (0.03 mg/kg, IM)으로 전처치하였으며, medetomidine 투여 10분 후 tiletamine/zolazepam (TZ)를 투여하였다. TZ투여 15분 후 atipamezole을 정맥으로 투여하였다. 실험견이 머리를 들 때까지의 평균시간은 대조군 43.06$\pm$2.60분, A30군 43.06$\pm$2.60분, A60군 32.83$\pm$8.13분 Al50군 14.36$\pm$1.60분으로 대조군과 비교할 때 A150군에서 유의성 있게 감소하였으나 (P<0.05) 완전한 보행을 보일 때까지의 평균시간에는 유의성이 나타나지 않았다. 회복기에 보이는 두부의 진전, 과도한 유연, 근육 경련과 같은 부작용은 atipamezole치 용량이 증가할수록 심하게 나타났다. 12두의 실험견중 5두가 medetomidine투여 후 5분 이내에 구토를 하였다. 대조군에서 심박수는 TZ 투여 후 15분을 제외하고, 모든 측정시간대에서 유의성 있는 감소를 나타내었으며, 전 실험군에서 medetomidine 투여 10분 후. A30군에서 atipamezole투여 후 40분에 심박수의 유의성 있는 감소가 나타났다 (P<0.05). Al50군에서는 atipamezole투여 10분 후 심계 항진 및 호흡 항진이 나타났다. 대다수 실험견에서 동맥혈압은 medetomidine과 tiletamine/zolazepam 투여 후 유의성 있게 감소하였으나 (P< 0.05) A60군과 Al50군에서는 atipamezole투여 후 점차적으로 회복되었다. 혈액가스검사와 총 혈구계산치는 유의성 있는 변화가 관찰되지 않았다 본 실험의 결과로 atipamezole 150 mg/kg은 MTZ 병용 마취견 각성에 뛰어난 효과를 나타낸다고 사료된다.

자연공원과 도시공원의 Soundscape 특성 차이 (Differences in the Soundscape Characteristics of a Natural Park and an Urban Park)

  • 김지연;이재윤;기경석
    • 한국환경생태학회지
    • /
    • 제31권1호
    • /
    • pp.112-118
    • /
    • 2017
  • 본 연구의 목적은 자연공원과 도시공원을 대상으로 soundscape 특성을 밝히는 것이다. 연구대상지는 강원도 원주시 자연공원(치악산국립공원)과 도시공원(장미공원)이었다. Soundscape 녹음은 Digital Recorder를 이용하였으며, 녹음기간은 2015년 4월부터 2016년 1월까지이었다. 분석기간은 계절별로 8일씩, 총 64일(2개소)이었다. 분석항목은 Soundscape의 일주기 변화, Soundscape 유형, 계절별 차이이었다. Soundscape의 일주기 변화 분석 결과, 자연공원은 태양의 주기에 맞추어 생물 소리가 우점하고 있었으며 주간에 비행기소리가 유입되고 있었다. 도시공원은 인위적 소리가 24시간 높은 빈도로 발생하고 있었다. Soundscape의 세부유형 분석 결과, 자연공원의 생물 소리는 야생조류, 포유류, 곤충류, 양서류로 분류되었고, 무생물 소리는 비 소리, 바람 소리로 분류되었다. 인위적 소리는 대부분 비행기 소리이었다. 도시공원의 생물 소리는 야생조류가 우점하였고, 무생물 소리는 비와 바람 소리가 주로 나타났다. 도시공원의 인위적 소리는 자동차, 사람, 음악, 공사, 청소, 비행기 소리 순으로 나타났다. Soundscape의 계절적 차이 분석 결과 생물소리는 자연공원이 도시공원보다 봄, 여름, 가을이 높은 것으로 통계적 유의성이 인정되었다. 인위적 소리는 도시공원이 자연공원보다 4계절 모두 높은 것으로 나타났다. 본 연구의 한국에서 서로 다른 경관에 속해 있는 자연공원과 도시공원을 대상으로 Soundscape 특성을 규명한 첫 번째 연구라는 측면에서 의미가 있다.

暴雨의 時間的 分布에 關한 硏究 (Studies on the Time Distribution of Heavy Storms)

  • 이근후
    • 한국농공학회지
    • /
    • 제26권2호
    • /
    • pp.69-84
    • /
    • 1984
  • This study was carried out to investigate the time distribution of single storms and to establish the model of storm patterns in korea. Rainfall recording charts collected from 42 metheorological stations covering the Korean peninsula were analyzed. A single storm was defined as a rain period seperated from preceding and succeeding rainfall by 6 hours and more. Among the defined single storms, 1199 storms exceeding total rainfall of 80 mm were qualified for the study. Storm patterns were cklassified by quartile classification method and the relationship between cummulative percent of rainfalls and cummulative storm time was established for each quartile storm group. Time distribution models for each stations were prepared through the various analytical and inferential procedures. Obtained results are summarized as follows: 1. The percentile frequency of quartile storms for the first to the fourth quartile were 22.0%, 26.5%, 28.9% and 22.6%, respectively. The large variation of percentile frequency was show between the same quartile storms. The advanced type storm pattern was predominant in the west coastal type storm patterns predominantly when compared to the single storms with small total rainfalls. 3. The single storms with long storm durations tended to show delayed type storm patterns predominantly when compared to the single storms with short storm durations. 4. The percentile time distribution of quartile storms for 42 rin gaging stations was estimated. Large variations were observed between the percentiles of time distributions of different stations. 5. No significant differences were generally found between the time distribution of rainfalls with greater total rainfall and with less total rainfall. This fact suggests that the size of the total rainfall of single storms was not the main factor affecting the time distribution of heavy storms. 6. Also, no significant difference were found between the time distribution of rainfalls with long duration and with short duration. The fact indicates that the storm duration was no the main factor affecting the time distribution of heavy storms. 7. In Korea, among all single storms, 39.0% show 80 to 100mm of total rainfall which stands for the mode of the frequency distribution of total rainfalls. The median value of rainfalls for all single storms from the 42 stations was 108mm. The shape of the frequency distribution of total rainfalls showed right skewed features. No significant differences were shown in the shape of distribution histograms for total rainfall of quartile storms. The mode of rainfalls for the advanced type quartile storms was 80~100mm and their frequencies were 39~43% for respective quartiles. For the delayed type quartile storms, the mode was 80~100mm and their frequencies were 36!38%. 8. In Korea, 29% of all single storms show 720 to 1080 minutes of storm durations which was the highest frequency in the frequency distribution of storm durations. The median of the storm duration for all single storms form 42 stations was 1026 minutes. The shape of the frequency distribution was right skewed feature. For the advanced type storms, the higher frequency of occurrence was shown by the single storms with short durations, whereas for the delayed type quartile storms, the higher frequency was shown gy the long duration single storms. 9. The total rainfall of single storms was positively correlated to storm durations in all the stations throughout the nation. This fact was also true for most of the quartile storms. 10. The third order polynomial regression models were established for estimating the time distribution of quartile storms at different stations. The model test by relative error method resulted good agreements between estimated and observed values with the relative error of less than 0.10 in average.

  • PDF