• Asian Pacific Journal of Cancer Prevention
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• v.15 no.22
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• pp.9853-9857
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• 2014

Background: The morbidity and mortality rate of liver cancer continues to rise in China and advanced cases respond poorly to chemotherapy. Ribosomal protein L24 has been reported to be a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cell growth of cancer. Materials and Methods: Total RNA of cultured amycin-resistant and susceptible HepG2 cells was isolated, and real time quantitative RT-PCR were used to indicate differences between amycin-resistant and susceptible strains of HepG2 cells. Viability assays were used to determine amycin resistance in RPL24 transfected and control vector and null-transfected HepG2 cell lines. Results: The ribosomal protein L24 transcription level was 7.7 times higher in the drug-resistant HepG2 cells as compared to susceptible cells on quantitative RT-PCR analysis. This was associated with enhanced drug resistance as determined by methyl tritiated thymidine (3H-TdR) incorporation. Conclusions: The ribosomal protein L24 gene may have effects on drug resistance mechanisms in hepatocellular carcinoma HepG2 cells.

• Journal of KIISE:Information Networking
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• v.27 no.1
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• pp.58-67
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• 2000

The paper presents a representative-based feedback mechanism and rate adaptation policy for congestion control in multicast traffic for multimedia applications. In multicast congestion control, feedback implosion occurs as many receivers send feedback to a sender. We propose to use representatives to avoid the feedback implosion. In our scheme, receivers feedback packet loss information periodically and a sender adapts the sending rate based on the information collected through a hierarchy of representatives. A representative is selected in each region and roles as a filter to decrease the number of feedbacks. The simulation results show that the proposed scheme solves the feedback implosion problem and well adapts in a congested situation.

• The Journal of the Korea Contents Association
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• v.1 no.1
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• pp.130-136
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• 2001

Real-time applications like VoIP in mobile networks need smooth handovers in order to minimize or eliminate packet loss as a mobile host(MH) transitions between network links. In this paper, we design a new variable buffering mechanism for IPv6 by which an MH can request that the router on its current subnet buffers pad(eta on its behalf while the MH completes registration procedures with the router of a new subnet. Performance results show that our proposed queueing scheme with a variable space allocation is quite appropriate for mobile internet environment in terms of the packet loss rate.

• Journal of Multimedia Information System
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• v.4 no.1
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• pp.9-18
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• 2017

Ubiquitous computing is a novel paradigm that is rapidly gaining in the scenario of wireless communications and telecommunications for realizing smart world. As rapid development of sensor technology, smart sensor system becomes more popular in automobile or vehicle. In this study, a new vehicle detection mechanism in real-time for blind spot area is proposed based on imaging sensors. To determine the position of other vehicles on the road is important for operation of driver assistance systems (DASs) to increase driving safety. As the result, blind spot detection of vehicles is addressed using an automobile detection algorithm for blind spots. The proposed vehicle verification utilizes the height and angle of a rear-looking vehicle mounted camera. Candidate vehicle information is extracted using adaptive shadow detection based on brightness values of an image of a vehicle area. The vehicle is verified using a training set with Haar-like features of candidate vehicles. Using these processes, moving vehicles can be detected in blind spots. The detection ratio of true vehicles was 91.1% in blind spots based on various experimental results.

• Journal of Information Processing Systems
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• v.3 no.2
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• pp.82-88
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• 2007

Web services are the new building block of today's Internet, and provides interoperability among heterogeneous distributed systems. Recently in web services environment, security has become one of the most critical issues. The hackers attack one of fragile point and can misuse legitimate user privilege because all of the connected devices provide services for the user control and monitoring in real time. Also, the users of web services must temporarily delegate some or all of their rights to agents in order to perform actions on their behalf. This fact risks the exposure of user privacy information. In this paper, we propose secure delegation model based on SAML that provides confidentiality and integrity about the user information in distributed systems. In order to support privacy protection, service confidentiality, and assertion integrity, encryption and a digital signature mechanism is deployed. We build web service management server based on XACML, in order to manage services and policies of web service providers.

• Journal of Information Processing Systems
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• v.5 no.2
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• pp.77-86
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• 2009

In this paper, we propose a framework for the real-time monitoring of wireless biosensors. This is a scalable platform that requires minimum human interaction during set-up and monitoring. Its main components include a biosensor, a smart gateway to automatically set up the body area network, a mechanism for delivering data to an Internet monitoring server, and automatic data collection, profiling and feature extraction from bio-potentials. Such a system could increase the quality of life and significantly lower healthcare costs for everyone in general, and for the elderly and those with disabilities in particular.

• Journal of Institute of Control, Robotics and Systems
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• v.22 no.5
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• pp.326-331
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• 2016

This paper presents a novel robust adaptive AC8B exciter system against synchronous generators for ships. A PID (proportional integral derivative) control framework, which is a part of the AC8B exciter system, is simply composed of nominal and auxiliary control configurations. For selecting these proper parameter values, the former is conventionally chosen based on the experience and knowledge of experts, and the latter is optimally estimated via a neural networks optimization procedure. Additionally, we propose an online parameter learning-based auxiliary control to practically cope with deterioration of control performance owing to uncertainty in electric generator systems. Such a control mechanism ensures the robustness and adaptability of an AC8B exciter to enhance control performance in real-time implementation. We carried out simulation experiments to test the reliability of the proposed robust adaptive AC8B exciter system and prove its superiority through a comparative study in which a conventional PID control-based AC8B exciter system is similarly applied to our simulation experiments under the same simulation scenarios.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2009.05a
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• pp.345-349
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• 2009

This test cell is developed to the institutes or laboratories research and study gas turbine engine for academic purpose with this test data to provide the fundamentals of operational mechanism and structural configuration, and further to verify thermodynamic calculation The test cell is installed to monitor and compare real-time data with reference engine model performance simulation data. using by NI DAQ(Data acquisition)device and LabVIEW program based on 30lbf-micro turbojet engine.

• Journal of the Microelectronics and Packaging Society
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• v.21 no.4
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• pp.25-31
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• 2014

Bioimaging has advanced the field of nanomedicine, drug delivery, and tissue engineering by directly visualizing the dynamic mechanism of diagnostic agents or therapeutic drugs in the body. In particular, wide-field, planar, near-infrared (NIR) fluorescence imaging has the potential to revolutionize human surgery by providing real-time image guidance to surgeons for target tissues to be resected and vital tissues to be preserved. In this review, we introduce the principles of NIR fluorescence imaging and analyze currently available NIR fluorescence imaging systems with special focus on optical source and packaging. We also introduce the evolution of the FLARE intraoperative imaging technology as an example for image-guided surgery.

• Journal of the Korean Society for Precision Engineering
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• v.15 no.5
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• pp.65-71
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• 1998

This paper presents in-process compensation methodology to eliminate cutter runout and improve machined surface quality. The cutter runout compensation system consists of the micro-positioning mechanism with the PZT (piezo-electric translator) which is embeded in the sliding table to manipulate the radial depth of cut in real time. For the implementation of cutter runout compensation methodology. cutting force adaptive control was proposed in the angle domain based upon PI (proportional-integral) control strategy to eliminate chip-load change in end milling process. Micro-positioning control due to adaptive acuation force response improves the machined surface quality by compensation or elimination of cutter runout induced cutting force variation. This results will provide lots of information to build-up the precision machining technology.