• Asian Pacific Journal of Cancer Prevention
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• v.17 no.4
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• pp.1823-1828
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• 2016

Background: Biological and pharmacological activities of dryocrassin ABBA, a phloroglucinol derivative extracted from Dryopteris crassirhizoma, have attracted attention. In this study, the apoptotic effect of dryocrassin ABBA on human hepatocellular carcinoma HepG2 cells was investigated. Materials and Methods: We tested the effects of dryocrassin ABBA on HepG2 in vitro by MTT, flow cytometry, real-time PCR, and Western blotting. KM male mice were used to detect the effect of dryocrassin ABBA on H22 cells in vivo. Results: Dryocrassin ABBA inhibited the growth of HepG2 cells in a concentration-dependent manner. After treatment with 25, 50, and $75{\mu}g/mL$ dryocrassin ABBA, the cell viability was 68%, 60% and 49%, respectively. Dryocrassin ABBA was able to induce apoptosis, measured by propidium iodide (PI)/annexin V-FITC double staining. The results of real-time PCR and Western ting showed that dryocrassin ABBA up-regulated p53 and Bax expression and inhibited Bcl-2 expression which led to an activation of caspase-3 and caspase-7 in the cytosol, and then induction of cell apoptosis. In vivo experiments also showed that dryocrassin ABBA treatment significantly suppressed tumor growth, without major side effects. Conclusions: Overall, these findings provide evidence that dryocrassin ABBA may induce apoptosis in human hepatocellular carcinoma cells through a caspase-mediated mitochondrial pathway.

• Journal of Korean Home Economics Education Association
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• v.1 no.1
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• pp.63-85
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• 1989

The Change of environment related to human life, science, technology, economics and education level have much effect on home life. Therefore Home Economics Education have to get out of past trite concept that it is only a method to become good housewife and take the role to widen the human life and to grow creative power as a academic part of science. For these, Home Economics should become life education, life education of secondary school has to have relation to lifelong education. To achieve effective result from Home Economics Education, the object, system and methods of Home Economics Education, the object, system and methods of Home Economics Education have to be improved and teaching material has to be studied systematically. As an object of aboves and education planning in clothing is made for deep understanding the study of Home Economics Teaching Material. And to understand the real state, made some questions, had interview with 63-teaching in Kangweon province and show the results. 1) Tab 1~20 are the level of recognition about object, teaching content, time structure of secondary school. The object is recognized as cultural education and basic job education. 2) Tab 21~30 show the real state of textbook and study of it. To take effect from school lecture other teaching material except textbook is required. 3) Tab 31~40 are the result of sewing and handicraft practice. Sewing and handicraft needs much time and almost all time is used in practicing. 4) Tab 42~54 are the planning of textbook study for effective teaching, self-estimation and teaching material making is also considered. All above is collarless blouse’s planning. Base on above result, all objects of clothing life should be teached. For the development of Home Economics Education 1) Understanding and affection of teachers is required. 2) To solve indicated problem, national policy, education plan in school and education finance are fully supported. 3) More studies is required in Home Economics Education.

• Hwankyungkyoyuk
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• v.13 no.2
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• pp.38-50
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• 2000

We are evidently Home Economicus, egoistic rational utility maximiger, and all the capitalism economic situation make us adapt to such life, and recognize that it is rational to act like that. This can be demonstrated in Prisoner′s Dilemma(PD) which always select the non-cooperative choice for free rider in rational selection process of public goods. This paper notice the "what is problem\ulcorner"The problem is not in free rider itself but in free rider egoism. The practical behavior of free rider egoism can be explained by way of Prisoner′s Dilemma. In PD situation, the prisoner makes a rational choice, non-cooperative alternative, but he doesn′arrive at preto-optimality. It is dilemma. Why can′t he arrive \ulcorner Because he is isolated from other prisoner. So we call it prisoner′s dilemma. The PD situation can be compared with our real economic life, which, we think, have kept by rational choice of the public goods. We actually have made our life as an individual one although we organized communities of capitalism. Of course, we know each others as members of same society, but each individual being can′t secure the belief, which has composed basis of community. So, it is very similar and common between PD situation and our real economic life in the production of public goods. We conclude that this non-cooperative process of PD situation can be utilized as instrument of EE. So this non-cooperative process can show us the effectiveness of EE as follows. \circled1 Game situation life PD can be used as good instrument for explaining the rational selection dilemma(error) to Homo-Economicus, the rational agent, with the optimal and rational language. \circled2 We can show that the selection result is dilemma, not arrive pareto - optimality. \circled3 The dilemma can be resolved with accomplishing the good communal life based on the belief, not on the isolation.

• Journal of the Korean Home Economics Association
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• v.38 no.8
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• pp.53-68
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• 2000

This study examines family life problems & solution of married women in Chonbuk area as a part of study on family life Issues. Data were collected by questionnaires. The sample consisted of 1142 married women. The major findings were summarized as follows : (1) The degree of recognition about family life problem is rated economic life > woman's parents-in-law> woman's real parents> spouse> children related problems. (2) In the family conflict solution types, the most used types is a rational. (3) The degree of recognition about the family violence is rated abusive languages of husband>husband behavior under the influence of alcohol wife's child abuse>husband's child abuse>abusive languages of wife>battered wife. (4) The kins are still considered the primary source for functions of personal support. Also, the needs for the children related equipments is higest among the public support equipments.

• Journal of Digital Contents Society
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• v.9 no.4
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• pp.645-652
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• 2008

The study of Artificial Life Art has affected the development of art using artificial life. Artificial Life Art started as a concern for microscopic organisms and has developed into works producing some creativities through the choices of spectators. The interests in real animals have resulted in the production of artificial animals such as cyber pets, and the interests in humans have been led to the creation of avatars. We will analyze the invisible emotional field of Naoko Tosa's works which use cyber pets and avatars, and clarify how the creative changes of Artificial Life Art affect the development of interactive art.

• Proceedings of the KSR Conference
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• 2009.05a
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• pp.1125-1131
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• 2009

This paper presents the evaluation of fatigue life for a journal box attached to rolling stock bogie under random dynamic loading condition. Because a journal box was under random dynamic loading conditions, the fatigue life assessment due to these loads requires the analysis considering the multiaxial effect of random dynamic loading. To do this work, the finite element analysis has been conducted to calculate random dynamic response using multiaxial acceleration data. Then, the fatigue life assessment of component has been conducted using vibration fatigue analysis applying the power spectral densities of the responses obtained through the FEA The results of fatigue life assessment were compared to the damage from the strain measurement. This study shows that can be evaluated the fatigue life assessment considering real service condition about a component attached to rolling stock bogie.

• YAKHAK HOEJI
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• v.56 no.1
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• pp.66-69
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• 2012

This study aims to assess the aggregate contribution of new drugs to the increase in life expectancy. We constructed a panel data combining mortality data in KOSIS and a drug dataset generated by assigning new drugs listed in 2000~2009 to their respective ICD codes. We found that 10% increase in stock of new drug led to 0.13~0.27% increase in the probability of survival to age 65. Due to lack of disease-specific life table, we used indirect approach to estimate the effect of new drugs on longevity. Using ordinary least squares, the estimate of the probability of survival to age 65 (logarithm) on life expectancy for all ages was 24.92. In conclusion, the increase in life expectancy of the entire population in Korea between 2000 and 2009 resulting from NMEs is 1.95 years, which explains 46.6% of real increase in life expectancy.

• Industrial Engineering and Management Systems
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• v.14 no.2
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• pp.183-195
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• 2015

In this paper, we propose a two-stage group acceptance sampling plan for generalized inverted exponential distribution under truncated life test. Median life is considered as a quality parameter. Design parameters are obtained to ensure that true median life is longer than a given specified life at certain level of consumer's risk and producer's risk. We also explore situations under which design parameters based on median lifetime can be used for other percentile points. Tables and specific examples are reported to explain the proposed plans. Finally a real data set is analyzed to implement the plans in practical situations and some suggestions are given.

• Journal of Industrial and Engineering Chemistry
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• v.67
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• pp.266-275
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• 2018

Herein, a novel operating life (OL) test method was evaluated with 200 mAh pouch-type lithium-ion batteries. By combining the calendar life (CL) test with intermediate pulse power cycling, more realistic life prediction was possible, which encompassed real operation of batteries accompanying with thermal acceleration. Larger capacity decrease and resistance increase of pouch cell were observed in the OL test, which was well explained using the SEI film growth model. After dissemble of pouch cell, capacity loss and resistance increase mostly occurred within anode, reflecting that SEI film growth on anode surface was highly attributable to cell degradation.

• Smart Structures and Systems
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• v.8 no.3
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• pp.275-302
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• 2011

This is a review paper on mathematical modeling of actively controlled piezo smart structures. Paper has four sections to discuss the techniques to: (i) write the equations of motion (ii) implement sensor-actuator design (iii) model real life environmental effects and, (iv) control structural vibrations. In section (i), methods of writing equations of motion using equilibrium relations, Hamilton's principle, finite element technique and modal testing are discussed. In section (ii), self-sensing actuators, extension-bending actuators, shear actuators and modal sensors/actuators are discussed. In section (iii), modeling of thermal, hygro and other non-linear effects is discussed. Finally in section (iv), various vibration control techniques and useful software are mentioned. This review has two objectives: (i) practicing engineers can pick the most suitable philosophy for their end application and, (ii) researchers can come to know how the field has evolved, how it can be extended to real life structures and what the potential gaps in the literature are.