• Title/Summary/Keyword: reactive group

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Differences in Body Weight, Dietary Efficiency, Brain Obesity Control Factor (AMPK), Reactive Oxygen Species (MDA), and Antioxidant Enzymes (SOD) in Young Mice According to the Intensity of Aerobic Exercise for 8 Weeks (8주간의 유산소 운동강도에 따른 어린 생쥐의 체중, 식이효율, 뇌의 비만조절 인자(AMPK), 활성산소(MDA), 항산화효소(SOD)의 차이)

  • Jeon, Mi Yang
    • Journal of Korean Biological Nursing Science
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    • v.23 no.3
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    • pp.247-255
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    • 2021
  • Purpose: The goal of this study was to see how different aerobic exercise intensities affected AMP-activated protein kinase (AMPK), reactive oxygen, and antioxidant enzymes in young mice during an 8-week period. Methods: Forty male C57BL/6 mice, aged seven weeks, were randomly assigned to one of four groups: control (n=10), low-intensity exercise (n=10), moderate-intensity exercise (n=10), and high-intensity exercise (n=10). For eight weeks, aerobic activity was performed once a day for 35-40 minutes, five days a week. The data were analyzed using descriptive statistics, analysis of variance (ANOVA), chi-squared tests, and the Tukey test in the SPSS/WIN 25.0 program. Results: Weight (p=.001) was substantially different between the moderate-intensity exercise group and the control group in AMPK (p<.001). In addition, there were no significant differences between the moderate-intensity exercise group and the control group in reactive oxygen malondialdehyde (MDA) levels (p=.136) and antioxidant enzyme superoxide dismutase (SOD) levels (p=.521). Conclusion: These findings suggest that moderate-intensity aerobic exercise increased AMPK activation and helped young mice shed weight.

Dye-resist Properties of Reactive Dye-resist Agents in Reactive Dyeing of Silk

  • Park, Sung-Hee;Oh, Myung-Joon;Koh, Joon-Seok
    • Textile Coloration and Finishing
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    • v.19 no.5
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    • pp.8-16
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    • 2007
  • The dye-resist effect of reactive dye-resist agents in reactive dyeing of silk was investigated. The dichlorotriazine-based dye-resists achieved a higher effectiveness than others since they make a charge barrier of diffusion in the silk fiber periphery due to high reactivity of dichlorotriazine group. Similarly, in the case of hetero-multifunctional dye-resist agent, the dye-resist agent containing both a dichlorotriazine and an ${\alpha}$-bromoacrylamide reactive groups achieved better resist effectiveness than those containing both a monochlorotriazine and an ${\alpha}$-bromoacrylamide groups. Also, their resist effectiveness was improved by increasing the number of sulfonate groups in the dye-resist agents and the number of reactive groups in the reactive dyes applied to them.

The Effects of the Sasa Borealis Leaves Extract on Plasma Adiponectin, Resistin, C-Reactive Protein and Homocysteine Levels in High Fat Diet-Induced Obese C57/BL6J Mice (조릿대 잎 추출물이 고지방식이 유도 비만 마우스 (C57/BL6J)의 혈장 Adiponectin, Resistin, C-reactive Protein 및 Homocysteine 농도에 미치는 영향)

  • Kim, Eun-Young;Jung, Eun-Young;Lim, Hyeon-Sook;Heo, Young-Ran
    • Journal of Nutrition and Health
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    • v.40 no.4
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    • pp.303-311
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    • 2007
  • As obesity is known to be related to hyperlipidemia, diabetes and coronary heart disease, and other chronic diseases, many researches have focused on functional food materials showing anti-obesity activity. The adipokines secreted by adipose tissue, resistin and adiponectin are known to play an important role in the pathogenesis of chronic diseases directly. C-reactive protein and homocysteine are molecules regulated by adipose tissue indirectly also relate to the chronic diseases. This study was performed to study of the anti-obesity effects of Sasa borealis in diet-induced obese mice (C57/BL6J). The mice were divided into four group: NFD (Normal fat diet), HFD (High fat diet), BSE (High fat diet containing 5% of 70% ethanol extract of Sasa borealis leaves), BLW (High fat diet containing 5% of water extract of Sasa borealis leaves). The experimental diets were fed for 11 weeks. The final body weight of the mice in the groups of BSE and BLW groups were significantly lower than the HFD group. The effects of weight reduction were due to reduced body fat accumulation. The adiponectin levels are significantly decreased in HFD group compared than NFD group and increased taken by Sasa borealis containing diet. The resistin levels are not significantly different between experimental groups. The CRP and homocyteine levels are significantly higher in HFD group than NFD group and significantly decreased by Sasa borealis containing diet, especially BLW group. These results indicate that orally administered Sasa borealis not only has the effect of reducing the body weight and total fat weight, but preferable effect in adiponectin levels and related molecules as CRP and homocysteine. Therefore we expect the Sasa borealis may have an anti-obesity function and anti-metabolic syndrome effect in diet-induced obese mice.

The Effects of Oral Cryotherapy on Oral Mucositis, Reactive Oxygen Series, Inflammatory Cytokines, and Oral Comfort in Gynecologic Cancer Patients Undergoing Chemotherapy: A Randomized Controlled Trial (구강 냉요법이 항암화학요법을 받는 부인암환자의 구내염, 활성산소, 염증성 사이토카인, 구강 안위감에 미치는 효과: 무작위대조군실험설계)

  • Shin, Nayeon;Kang, Younhee
    • Journal of Korean Academy of Nursing
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    • v.49 no.2
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    • pp.149-160
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    • 2019
  • Purpose: The purpose of this study was to examine the effects of oral cryotherapy on oral mucositis, reactive oxygen series, inflammatory cytokines, and oral comfort in patients undergoing chemotherapy for gynecologic cancers. Methods: Participants were randomly assigned to the experimental group (n=25, receiving oral cryotherapy during chemotherapy) and the control group (n=25, receiving the usual care consisting of 0.9% normal saline gargles three times before meals). Oral mucositis was assessed using the oral assessment guide, while oral comfort was assessed using the oral perception guide. Reactive oxygen series was measured as total oxidant stress, and the level of two inflammatory markers, interleukin-6 (IL-6) and tumor necrosis factor-alpha ($TNF-{\alpha}$), were examined. The data were analyzed using t-test, chi-square test, Fisher's exact test, Mann-Whitney U-test, and repeated measures analysis of variance. Results: There was a significant difference in the oral mucositis score, reactive oxygen series score, $TNF-{\alpha}$ level, and oral comfort score between the two groups, and there were significant changes over time and in the group-by-time interactions. There was a significant difference in the IL-6 score between the two groups, but there were no significant changes over time or in the group-by-time interactions. Conclusion: The study results revealed that oral cryotherapy was more effective than the usual care regime of normal saline gargles for reducing oral mucositis, reactive oxygen series, and inflammatory cytokines and for improving oral comfort in gynecologic cancer patients undergoing chemotherapy.

Preparation and Dyeability of Reactive Dyes Fixable at Neutral pH (중성욕 고착형 반응성 염료의 제조 및 그의 염색성)

  • Choi, Chang Nam;Lee, Young Mi;Lee, Woong Eui
    • Textile Coloration and Finishing
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    • v.9 no.3
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    • pp.42-49
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    • 1997
  • In order to study the dyeability of reactive dyes fixable at neutral pH, three reactive dyes(DYE-NC, DYE-PC, and DYE-LC) were prepared by the reaction of Cibacron Brilliant Red 3B-A with nicotinic acid, pyridine, and lutidine, respectively. FT-IR and UV/Vis spectrophometry were used to identify the dyes prepared. While the maximum absorption wavelength (&{\lambda}_{max}&) of Cibacron Brilliant Red 3B-A was 515nm, the &{\lambda}_{max}& of DYE-NC, DYE-PC, and DYE-LC were 522nm, 525nm, and 536nm, respectively. The &{\lambda}_{max}& was shifted to the longer wavelength by introducing the electron donating groups to the pyridine ring of Cibacron Brilliant Red 3B-A. All of the reactive dyes synthesized showed good exhaustion and fixation property to cotton fabric at higher temperature and neutral pH condition. It was regarded that the quaternary pyridinium ion functionated as the leaving group instead of the chloride ion. Among them, DYE-NC showed the best dyeability at the above condition. It was considered that the electron withdrawing carboxylic acid group in nicotinic acid enhanced the cationic property of nitrogn in pyridine ring, resulting the good reactivity with OH group in cellulose.

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Printing of Polyester and Cotton Blends using Diaminoanthraquinone Disperse Dye and Monochlorotriazinyl Reactive Dye Mixtures (디아미노안트라퀴논계 분산염료/모노클로로트리진형 반응염료에 의한 폴리에스테르/면 혼방 직물의 날염)

  • 강숙녀
    • Textile Coloration and Finishing
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    • v.6 no.2
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    • pp.30-39
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    • 1994
  • To study the printing behaviors of Polyester and cotton(P/C) fabrics printed with disperse and reactive dyes, the effects of alkalis on the fixation of reactive dyes and the alkali-stability of disperse dyes in various methods of fixation were examined. The anthraquinone disperse dyes which have diamino derivatives as substituents without hydroxy group, such as C.I. Disperse Violet 1(D.V.1), C.I. Disperse Violet 28(D.V.28) and C.I.Disperse Blue 60(D.B.60) showed good results of fixation without regard to the concentration of NaHCO$_3$. In case of high temperature steaming(HTS) and unsaturated steaming(US)/HTS, D.V. 1 was alkali-stable and effective for P/C printing. A good result was obtained with D.V.1 and C.I.Reactive Orange 13(R.O.13) paste of 4% $K_{2}CO_{3}$. It was found that the unfixed D.V.28 bearing chloro group can hinder the fixation of monochlorotriaxinyl reactive dyes, and D.B.60 made little stain on 100% cotton. In thermosol(Tm), the dye uptake of D.V.1 was not decreased so much, but those of D.V.28 and D.B.60 were greatly decreased.

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Treadmill exercise enhances motor coordination and ameliorates Purkinje cell loss through inhibition on astrocyte activation in the cerebellum of methimazole-induced hypothyroidism rat pups

  • Shin, Mal-Soon;Kim, Bo-Kyun;Lee, Shin-Ho;Kim, Tae-Soo;Heo, Yu-Mi;Choi, Jun-Ho;Kim, Chang-Ju;Lim, Baek-Vin
    • Korean Journal of Exercise Nutrition
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    • v.16 no.2
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    • pp.73-84
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    • 2012
  • Thyroid hormones are important for the development of the brain including the cerebellum. In the present study, we investigated the effect of treadmill exercise on the survival of Purkinje neurons and the activation of astrocytes in the cerebellar vermis of hypothyroidism-induced rat pups. On the day of perinatal 14, pregnant rats were divided into two groups (n = 5 in each group): the pregnant control group and the pregnantmethimazole (MMI)-treated group. For the induction of hypothyroidism in the rat pups, MMI was added to the drinking water (0.02% wt/vol), from the day of perinatal 14 to postnatal 49. After delivery, male rat pups born from the pregnant control group were assigned to the control group. Male rat pups born from the MMI-treated group were divided into the hypothyroidism-induction group, the hypothyroidism-induction with treadmill exercise group, and the hypothyroidism-induction with thyroxine (T4) treatment group (n = 10 in each group). The rat pups in the exercise group were forced to run on a treadmill for 30 min once a day for 4 weeks, starting on postnatal day 22. In the hypothyroidism-induced rat pups, motor coordination was reduced and Purkinje cell death and reactive astrocytes in the cerebellar vermis were increased. Treadmill exercise enhanced motor coordination, increased the survival of Purkinje neurons, down-regulated reactive astrocytes, and enhanced brain-derived neurotrophic factor (BDNF) and receptor tyrosine kinase B (TrkB) expressions in the hypothyroidism-induced rat pups. These results suggest that treadmill exercise has beneficial effects in terms of protecting against thyroid dysfunction by increasing T3 and T4 and the related protein, BDNF, as well as TrkB, inhibition on astrocyte activation and the reduction of Purkinje cell loss regarding the cerebellum in hypothyroidism rat pups.

Dyeing of Polyvinyl Alcohol Fibers in Filament Yarn Form with Reactive and Vat Dyes

  • Rashad, Mahmood;Kim, Sam-Soo;Huh, Man-Woo;Yoon, Nam-Sik
    • Textile Coloration and Finishing
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    • v.19 no.5
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    • pp.17-23
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    • 2007
  • As polyvinyl alcohol(PVA) filament yarn is commercially used in many fields due to its high strength and modulus properties. This research was carried out to study the dyeing behavior of PVA and to find out appropriate dye for better dyeing. As the dyeing behavior of PVA fiber is similar to cellulose due to the same functional group, reactive and vat dyes were selected for the dyeing. Color strength of PVA fibers treated with vat dyes was found to be better than those with reactive dyes, because of the low fixation of reactive dye on fibers. Most of the reactive dye may became hydrolyzed, and flushed away with water in washing. Colorfastness to laundering was shown to be very high for both of the reactive-dyed and vat-dyed PVA fibers.

Synthesis and Photopolymerization of Vinyl Ether and Epoxy-Functionalized Silicones

  • Pyun, Sang-Yong;Kim, Whan-Gi
    • Macromolecular Research
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    • v.11 no.3
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    • pp.202-205
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    • 2003
  • The reactive precursors, vinyl ethers, and epoxy-silicones, were synthesized. The vinyl ether monomers were prepared from primary alcohol and ethyl vinyl ether with mercury (II) acetate. The epoxy-functionalized silicones have been achieved by the controlled, rhodium-catalyzed, chemoselective hydrosilation of vinyl ether with siloxanes or silane. It was shown that the hydrosilation proceeds exclusively at the vinyl ether group of alkenyl vinyl ether without participation at the alkenyl group. The photoinduced cationic polymerization of these monomers was studied and found to be all highly reactive.

A Study on the Dyeability of the Aminized Cotton Fabrics (아민기를 도입한 면직물의 염색성에 관한 연구)

  • 최연주;유효선
    • Journal of the Korean Society of Clothing and Textiles
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    • v.19 no.1
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    • pp.51-56
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    • 1995
  • Cotton fabric was treated with acrylonitrile in t-butyl alcohol and then aminized by reduction of the resultant cyanoethyl cellulose with LiAIH4, under various temperatures and times. Aminized cotton fabric toras dyed with acid and reactive dye. Dyeability as to temperatures, pH, and color fastness were compared to the amiRe group content of treated cotton fabrics. The results of this study were as follow: 1. D.S of cyanoethyl cellulose has been increased by increasing treating temperatures and times. Maximum D.S of cyanoethyl cellulose was 1.45. By SEM and the tensile strength, the damage of the treated cotton was not observed. 2. Since aminized cotton has greater affinity on acid dye than untreated cotton, dyeability increased with the increase of amino group content, and the lower pH, $60^{\circ}C$. 3. Since amino group in aminized cotton changes surface charge of cotton, dyeability for reactive dye increased by increasing the amino group content. Optimum dyeability was obtained at pH 5-7, $40^{\circ}C$. And dyeability of the amine treated cotton increased with the NaCl conc. 4. Color fastness to washing & light of the amine treated cotton was very low except for the wash fastness of the reactive dye.

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