• Title/Summary/Keyword: reactions

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Clinical characteristics of adverse reaction to radiocontrast media in children - A single center experience (소아에서 방사선 조영제 유해반응의 임상적 특징)

  • Kim, Min Jung;Lee, Bo Ra;Choi, Young Hun;Kang, Dong Yoon;Kang, Hye-Ryun;Suh, Dong In
    • Allergy, Asthma & Respiratory Disease
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    • v.6 no.6
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    • pp.315-321
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    • 2018
  • Purpose: Radiocontrast media are widely used in medical imaging to improve diagnostic accuracy. However, studies on the adverse reactions of radiocontrast media in children are limited. We aimed to describe the characteristics of adverse reactions to radiocontrast media among children who had a computed tomography scan or magnetic resonance imaging in a tertiary university hospital. Methods: We retrospectively collected data on adverse reactions to radiocontrast media by the reporting system of a tertiary university hospital. We selected data from children under the age of 19 from July 2011 to December 2017 and analyzed their characteristics. We focused mainly on the characteristics of the index case which is defined by the first adverse event of each subject. Results: During the period, a total of 88,050 radiocontrast media-enhanced imaging studies were performed and 184 cases of adverse reactions were reported. A total of 71 were identified as index cases. Forty-nine (69.0%) were male and the mean age was $12.7{\pm}3.2$ years. The incidence of radiocontrast media-related adverse reactions was 0.09% and severe reactions were 0.002%. The most common clinical feature was skin manifestations (54.9%), followed by gastrointestinal symptoms (40.8%) and neuropsychiatric symptoms (7.4%). Conclusion: Adverse reactions to radiocontrast media rarely occur in children and the incidence of severe reactions is low. Most reactions are mild and are related to the skin and gastrointestinal system. This report would provide good evidence for establishing a management strategy in children scheduled for imaging studies using radiocontrast media.

Relationships between Parent's Reactions to Preschoolers' Negative Emotions, Coping Styles and Peer Acceptance (유아의 부정적 정서에 대한 부모의 반응유형, 유아의 대처반응 및 또래수용간의 관계 연구)

  • Kang, Hee Yeon;Kang, Moon Hee
    • Korean Journal of Child Studies
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    • v.20 no.3
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    • pp.171-182
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    • 1999
  • This study examined the relations between parents' reactions to their preschool child's negative emotions, coping styles, and peer acceptance. Subjects were 250 5-year-old preschoolers and their parents. Instruments were the Coping with children's Negative Emotions Scale, and coding strategies checklist and peer rating scales for children. Data were analyzed with the SPSS PC + program. Parent's emotion-focused reactions, encouragement of expression and problem-focused reactions were positively associated with both peer acceptance and child coping styles whereas parent's distress, and punitive and minimizing reactions were associated with lower Peer acceptance and child coping styles of venting, denial, aggressive action, and avoidance. In child coping styles, problem solving was positively associated with peer acceptance while aggressive action anti venting were associated with a lower level of peer acceptance. Problem solving tended to be positively associated with peer acceptance, whereas aggressive action and venting tended to be associated with lower level of peer acceptance. (4) There was a statistically significant relations among parent's reactions to preschoolers' negative emotions, preschoolers' coping styles, and peer acceptance. There were the positive relations among parent's supportive reactions preschoolers' coping styles of problem solving and seeking support, and peer acceptance.

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The Effect of Mother's Reactions to Children's Negative Emotions on Children's Peer Relations : The Mediating Role of Children's Empathy and Emotional Regulation Types (아동의 부정적 정서표현에 대한 어머니 반응이 또래관계에 미치는 영향에서 아동의 공감과 정서조절 방식의 매개효과)

  • Oh, Ji-Hyun
    • Korean Journal of Child Studies
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    • v.36 no.2
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    • pp.17-37
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    • 2015
  • The study examined the pathways from maternal reactions to children's negative emotions to children's peer relations through children's empathy and emotional regulation. The participants in this study comprised 463 elementary school 4th-6th graders. They completed questionnaires on maternal reactions to children's negative emotions, levels of children's empathy, maladaptive emotion regulation types and skill levels of children's peer relations. Data were analyzed by means of structural equation modeling. It was found that in the case of maternal emotion coaching reactions, when done indirectly, as well as directly, had an influence on their levels of peer relations. On the other hand, in the case of over-sensitive maternal reactions, when done indirectly, but not directly, had an influence on their levels of peer relations. Therefore, these results indicate that children's empathy mediated the effects of maternal emotion coaching and over-sensitive reactions on peer relations. It also found that there are distinct pathways from maternal reaction types to children's negative emotions to peer relations through empathy and maladaptive emotion regulation types.

Parents' Emotional Reactions to Preschoolers' Negative Emotions, Emotional Knowledge, and Emotional Reaction: A Comparison Between Low-income and Middle-income Preschoolers (유아의 부정적 정서에 대한 부모의 정서반응과 유아의 정서지식 및 정서반응 - 저소득층 유아와 중류층 유아의 비교 -)

  • Sung, Mi-Young;Choi, In-Suk;Lee, Kang-Yi
    • Journal of the Korean Home Economics Association
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    • v.45 no.8
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    • pp.61-75
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    • 2007
  • This study investigated preschoolers' emotional knowledge, emotional reactions and parents' emotinal reactions to children's negative emotions according to their family income and sex. Subjects were 99 five-year-olds(46 low-income preschoolers, 53 middle-income preschoolers) recruited from three day-care centers and a kindergarten in Seoul and their parents. Each child was individually interviewed with pictorial tasks and parents reported on their own reactions by questionnaires. Results showed that low-income preschoolers were lower than middle-income preschoolers in emotional knowledge. Low-income preschoolers showed higher level of perceptions of the peer's anger in emotional reactions than middle-income preschoolers. Low-income mothers also were more likely than middle income mothers to show punitive reaction in parents' emotional reactions.

Photo-induced inter-protein interaction changes in the time domain; a blue light sensor protein PixD

  • Terazima, Masahide
    • Rapid Communication in Photoscience
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    • v.4 no.1
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    • pp.1-8
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    • 2015
  • For understanding molecular mechanisms of photochemical reactions, in particular reactions of proteins with biological functions, it is important to elucidate both the initial reactions from the photoexcited states and the series of subsequent chemical reactions, e.g., conformation, intermolecular interactions (hydrogen bonding, hydrophobic interactions), and inter-protein interactions (oligomer formation, dissociation reactions). Although time-resolved detection of such dynamics is essential, these dynamics have been very difficult to track by traditional spectroscopic techniques. Here, relatively new approaches for probing the dynamics of protein photochemical reactions using time-resolved transient grating (TG) are reviewed. By using this method, a variety of spectrally silent dynamics can be detected and such data provide a valuable description about the reaction scheme. Herein, a blue light sensor protein TePixD is the exemplar. The initial photochemistry for TePixD occurs around the chromophore and is detected readily by light absorption, but subsequent reactions are spectrally silent. The TG experiments revealed conformational changes and changes in inter-protein interactions, which are essential for TePixD function. The TG experiments also showed the importance of fluctuations of the intermediates as the driving force of the reaction. This technique is complementary to optical absorption detection methods. The TG signal contains a variety of unique information, which is difficult to obtain by other methods. The advantages and methods for signal analyses are described in detail in this review.

Study of Parental Reactions to a Child's Negative Emotions (유아의 부정적 정서에 대한 부모의 반응에 관한 연구)

  • Chung, Myoung-Ja;Lim, You-Kyoung;Kim, Dong-Rye
    • Korean Journal of Human Ecology
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    • v.20 no.6
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    • pp.1109-1119
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    • 2011
  • The purpose of this study was to examine the difference of the father's and mother's reactions to their children's negative emotions, relations among the children's variables, parent's variables, and parent's reactions. The subjects selected were 183 mothers and 183 fathers with children aged three to five-years-old, from a childcare center and kindergarten in Kwang-ju. Parental emotion-related practices regarding children's negative emotions were assessed with an adaptation of the CCNES(Fabes et al, 1990) that was modified by Kim Hee-Jung(1994). Descriptives, Pearson's correlation coefficient, were used for data analysis by using the SPSS 15.0 program. The results of this study can be summarized as follows: First, fathers and mothers used more positive reactions than negative reactions when their children showed negative emotions. The mothers were significantly higher than fathers on encouragement of expression, punitive, and distress reactions. Second, the children's age and gender, parent's age, level of education and income were negatively and positively correlated to the father's and mother's reactions to their children's negative emotions.

Studies on the Polarographic Kinetic Currents for the First Order Reactions at the Droping Mercury Electrode (水銀滴下電極에서 一次反應에 對한 포라로그라프電流에 關한 硏究)

  • Kim, Hwang-Am;Chin, Chang-Hee
    • Journal of the Korean Chemical Society
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    • v.6 no.1
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    • pp.14-18
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    • 1962
  • Solution to the diffusion layer for the first order reaction at a droping mercury electrode (D.M.E.) is presented. Equations are derived for polarographic currents for the reactions at the D.M.E. A factor which is applicable to the D.M.E. is derived, when we use the equations of the polarographic currents for the reactions at a plane electrode(P.E.), and the rate constants of the backward reactions are negligibly small. Polarographic currents from a combination of diffusions and reactions are obtained at the D.M.E. with special approximation. Rate constant for the reaction of ferrous ion with hydrogen-peroxide is determined at the D.M.E.,using the data of Kolthoff and Perry. The agreement of the equation with the data of Kolthoff and Perry for the kinetic current of ferric ion in the presence of hydrogen-peroxide is good. Ratios of diffusion layer at the D.M.E. to the diffusion layer at the P.E. are discussed and show that, when the rate constants of the backward reactions for the first order reactions are larger than 1/0.05 sec-1. and drop-time about 3 sec., these ratioes are about one.

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Social Relief Scheme for Serious Adverse Drug Reactions - Lessons from other countries for Korea (외국의 의약품 부작용 피해구제제도 현황과 국내 실시 방안)

  • Park, Sylvia;Chae, Su-Mi
    • Korean Journal of Clinical Pharmacy
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    • v.18 no.1
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    • pp.18-27
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    • 2008
  • This study investigated social relief schemes for serious adverse drug reactions in foreign countries and deduced lessons and implications for Korea to implement the scheme. A social relief scheme for serious adverse drug reactions provides reliefs for diseases and such health effects as disabilities or deaths that were caused by adverse reactions to pharmaceuticals prescribed at hospitals and clinics as well as those purchased at pharmacies notwithstanding their proper use. The US and the UK do not have specific relief schemes for adverse drug reactions but apply rules of strict liability or negligence. New Zealand and Nordic countries provide no-fault compensation schemes for health effects or injuries caused by medical treatments or medicinal products. Japan and Taiwan have operated the schemes since 1980 and 2000, respectively. In designing the scheme in Korea, we suggested that cases eligible for relief be confined to serious adverse reactions such as death or disability and then extended to diseases. It is desirable to encourage the reporting system of adverse drug reactions and quality use of medicines for the relief scheme to work efficiently.

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Comparative Analysis of Death-Related Iodide Contrast Media due to Adverse Reactions of Contrast Media in Computed Tomography (컴퓨터단층촬영의 요오드화 조영제 부작용으로 인한 사망 관련 조영제 비교 분석)

  • Yu, Seong-Min;Han, Dong-Kyoon;Hong, Joo-Wan
    • Journal of radiological science and technology
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    • v.44 no.1
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    • pp.47-52
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    • 2021
  • The incidence of adverse reactions to iodide contrast media was found to have increased owing to their increased use in computed tomography, but the exact reasons were unknown. Based on reported iodide contrast media adverse reactions data, it is recommended to the components of iodide contrast media before use to minimize adverse reactions. It was found that the use of iopromide and iomeprol in iodide contrast media resulted in a higher incidences of death and threat of life resulting from adverse reactions than other ingredients. Patients who are administered iodide contrast media containing iopromide and iomeprol during the computed tomography test should be carefully examined by the relevant medical professional, as the significance of gender and age varies from component to component. As multiple iodide contrast agents are available, the use of an appropriate iodide contrast media will reduce the incidence of iodide contrast media adverse reactions.

Users' Reactions to Rape News Shared on Social Media: An Analysis of Five Facebook Reaction Buttons

  • Al-Zaman, Md. Sayeed;Ahona, Tasnuva Alam
    • Asian Journal for Public Opinion Research
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    • v.10 no.1
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    • pp.51-73
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    • 2022
  • This study investigated 3.50 million Facebook reactions collected from 9,429 Bangladeshi news items about rape shared on social media from 2016 to 2021. The primary aim of this study was to understand users' different reaction patterns based on the five major Facebook reactions (i.e., love, haha, wow, sad, and angry). Based on the theories of emotion, we quantitatively answer one research question: How do social media users react to rape with the five major Facebook reactions? The results suggest that users are more likely to express disdain toward rape and sympathy toward the victims using Facebook reactions by using the angry button, along with the sad button. In rape news, both reactions are consistent and maintain a strong positive correlation, meaning they increase and decrease together. Although many users tend to mock and laugh at rape incidents and the victims, trend lines suggest that such expressions may not be consistent with time. Despite contextual relevance, we presume that in socially and morally unacceptable events like rape and war, the valences of reactions alter to some extent: angry and sad usually become positive, while love, wow, and haha become negative. Some strengths and limitations of the study are discussed as well.