• Title/Summary/Keyword: rate-independent model

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Optimization of Total Flavonoids Extraction Process from Wheat Sprout using Central Composite Design Model (중심합성계획모델을 이용한 밀싹으로부터 플라보노이드성분의 추출공정 최적화)

  • Lee, Seung Bum;Wang, Xiaozheng;Yoo, Bong-Ho
    • Applied Chemistry for Engineering
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    • v.29 no.4
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    • pp.446-451
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    • 2018
  • Effective ingredients were extracted using wheat sprout with high levels of flavonoids, and the extraction process was optimized with a central composite design model. The response value of the central composite design model establishes the extraction yield and the content of the flavonoids. The main and interactive effects were then analyzed depending on independent variables such as the extraction time, the volume ratio of alcohol to ultrapure water, and the extraction temperature. The extraction time and temperature were relatively large for the extraction yield. For the total flavonoids, the extraction time was most significantly affected. Considering both the extraction yield and the content of the total flavonoids, optimal extraction conditions were as follows: the extraction time (2.44 h), volume ratio of alcohol to ultrapure water (50.00 vol%), extraction temperature ($54.41^{\circ}C$). Under these condition, the extraction yield was 30.14 wt% and the content of the total flavonoids was $35.37{\mu}g\;QE/mL\;dw$. From the actual experimental result, the extraction yield under this condition was 29.92 wt% and the content of the total flavonoids was $35.32{\mu}g\;QE/mL\;dw$, which had an error rate of 0.39% and 0.74%, respectively. This is a multi-analysis comprehensive analysis that analyzes two simultaneous values of responses, but is considered to be highly accurate and also provides an excellent reliability of the optimization process in this study.

Estimation of heritability and genetic correlation of body weight gain and growth curve parameters in Korean native chicken

  • Manjula, Prabuddha;Park, Hee-Bok;Seo, Dongwon;Choi, Nuri;Jin, Shil;Ahn, Sung Jin;Heo, Kang Nyeong;Kang, Bo Seok;Lee, Jun-Heon
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.1
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    • pp.26-31
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    • 2018
  • Objective: This study estimated the genetic parameters for body weight gain and growth curve parameter traits in Korean native chicken (KNC). Methods: A total of 585 $F_1$ chickens were used along with 88 of their $F_0$ birds. Body weights were measured every 2 weeks from hatching to 20 weeks of age to measure weight gain at 2-week intervals. For each individual, a logistic growth curve model was fitted to the longitudinal growth dataset to obtain three growth curve parameters (${\alpha}$, asymptotic final body weight; ${\beta}$, inflection point; and ${\gamma}$, constant scale that was proportional to the overall growth rate). Genetic parameters were estimated based on the linear-mixed model using a restricted maximum likelihood method. Results: Heritability estimates of body weight gain traits were low to high (0.057 to 0.458). Heritability estimates for ${\alpha}$, ${\beta}$, and ${\gamma}$ were $0.211{\pm}0.08$, $0.249{\pm}0.09$, and $0.095{\pm}0.06$, respectively. Both genetic and phenotypic correlations between weight gain traits ranged from -0.527 to 0.993. Genetic and phenotypic correlation between the growth curve parameters and weight gain traits ranged from -0.968 to 0.987. Conclusion: Based on the results of this study population, we suggest that the KNC could be used for selective breeding between 6 and 8 weeks of age to enhance the overall genetic improvement of growth traits. After validation of these results in independent studies, these findings will be useful for further optimization of breeding programs for KNC.

A Pathway Analysis on Determination of Nursery Teachers' Reporting Intention for Child Abuse: Focused on Planned Behavior Theory (보육교사의 아동학대 신고의도 결정 경로 분석 -계획행동이론 중심-)

  • Kim, Ji-Woon;Kim, Yong-Duck
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.12
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    • pp.425-436
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    • 2019
  • This study constructs independent potential variables that are variables expected to affect child abuse reporting intention of child care teachers. In addition, this study establishes a research model based on the relationships between potential variables according to the results of previous studies and planning behavior theory. The purpose of this study was to examine what factors affect and how reporting intention is determined. The subjects of this study included a convenience sample of nursery teachers working in 67 daycare centers in the C region. The following results were obtained. First, the research model proposed in this study was found to be a suitable model to explain the child abuse teacher's intention to report child abuse through the analysis of the measurement and structural models. Second, the child abuse teacher's knowledge of child abuse is an important factor explaining the reporting intention and has an indirect effect through the mediation. Third, attitudes toward reporting of child care teachers were found to be the most direct factor that predicts reporting intentions. Fourth, subjective norms and reporting intentions of child care teachers were not statistically significant. Bsead on these results, basic data for improving child abuse reporting rate of childcare teachers were presented.

Aging and Poverty -Focusing on Age Group Differences in Poverty Trajectories- (노인되기와 빈곤 -빈곤 궤적의 연령집단 차이를 중심으로)

  • Lee, Ji-In;Joo, Eun-Sun
    • Journal of the Korea Convergence Society
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    • v.11 no.5
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    • pp.261-273
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    • 2020
  • The purpose of this study is to examine the trajectories of multi-dimensional poverty in the process of transitioning from middle age to old age, and to identify the factors that influence them. Using the Korea Welfare Panel Data(2006 ~ 2018), we examined the trajectory of changes in multi-dimensional poverty for 13 years by prospective elderly and middle aged group aged 55 or older in 2006 through the potential growth model. Multidimensional poverty is divided into seven dimensions in four areas: economy (income, employment), environment (residential), health, social culture (leisure, family relations, and social relations). The results showed that the level of multi-dimensional poverty decreased with time, and the overall poverty level was higher than that of the pre-old and the average. As a result of analyzing the condition model with the independent variable, the variables affecting poverty change were found in the order of spouse free and educational level for the elderly and gender and education level for the elderly. In other words, multi-dimensional poverty is gradually improving, but the rate of change and the variables that affect each age group are different.

Diagnosis and Visualization of Intracranial Hemorrhage on Computed Tomography Images Using EfficientNet-based Model (전산화 단층 촬영(Computed tomography, CT) 이미지에 대한 EfficientNet 기반 두개내출혈 진단 및 가시화 모델 개발)

  • Youn, Yebin;Kim, Mingeon;Kim, Jiho;Kang, Bongkeun;Kim, Ghootae
    • Journal of Biomedical Engineering Research
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    • v.42 no.4
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    • pp.150-158
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    • 2021
  • Intracranial hemorrhage (ICH) refers to acute bleeding inside the intracranial vault. Not only does this devastating disease record a very high mortality rate, but it can also cause serious chronic impairment of sensory, motor, and cognitive functions. Therefore, a prompt and professional diagnosis of the disease is highly critical. Noninvasive brain imaging data are essential for clinicians to efficiently diagnose the locus of brain lesion, volume of bleeding, and subsequent cortical damage, and to take clinical interventions. In particular, computed tomography (CT) images are used most often for the diagnosis of ICH. In order to diagnose ICH through CT images, not only medical specialists with a sufficient number of diagnosis experiences are required, but even when this condition is met, there are many cases where bleeding cannot be successfully detected due to factors such as low signal ratio and artifacts of the image itself. In addition, discrepancies between interpretations or even misinterpretations might exist causing critical clinical consequences. To resolve these clinical problems, we developed a diagnostic model predicting intracranial bleeding and its subtypes (intraparenchymal, intraventricular, subarachnoid, subdural, and epidural) by applying deep learning algorithms to CT images. We also constructed a visualization tool highlighting important regions in a CT image for predicting ICH. Specifically, 1) 27,758 CT brain images from RSNA were pre-processed to minimize the computational load. 2) Three different CNN-based models (ResNet, EfficientNet-B2, and EfficientNet-B7) were trained based on a training image data set. 3) Diagnosis performance of each of the three models was evaluated based on an independent test image data set: As a result of the model comparison, EfficientNet-B7's performance (classification accuracy = 91%) was a way greater than the other models. 4) Finally, based on the result of EfficientNet-B7, we visualized the lesions of internal bleeding using the Grad-CAM. Our research suggests that artificial intelligence-based diagnostic systems can help diagnose and treat brain diseases resolving various problems in clinical situations.

The Effects of Internal and External Factors of the Founders' on Startup Success: Focusing on the Mediating Effect of Self-efficacy and Trust in the Business Model (스타트업 창업자의 창업성공에 미치는 영향 요인에 관한연구: 비즈니스 모델에 대한 자기 효능감과 신뢰의 매개효과를 중심으로)

  • Lee, Il Bum;Kang, Min Jung;Kim, Ji Woong
    • The Journal of the Convergence on Culture Technology
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    • v.8 no.1
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    • pp.361-370
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    • 2022
  • This paper suggested a plan to increase the start-up survival rate by identifying independent variables that significantly affect start-up success through analysis of the founder's internal and external factors. As a result of this study, it was found that internal factors (financial ability, risk sensitivity) and external factors (start-up environment, start-up support policy) had a direct positive (+) effect on start-up success. Meanwhile, self-efficacy for business models partially mediated the relationship between factors(financing ability, risk sensitivity, start-up environment and start-up support policies) and start-up success. Self-efficacy for business models fully mediated the relationship between factors(start-up expertise and challenge spirit) and start-up success. Finally, trust in business models partially mediated the relationship between factors(start-up expertise, risk sensitivity, and start-up support policies) and start-up success. And the trust in business models fully mediated the factors(the spirit of challenge, start-up environment) and start-up success.

A Study on the Prediction Model of Stock Price Index Trend based on GA-MSVM that Simultaneously Optimizes Feature and Instance Selection (입력변수 및 학습사례 선정을 동시에 최적화하는 GA-MSVM 기반 주가지수 추세 예측 모형에 관한 연구)

  • Lee, Jong-sik;Ahn, Hyunchul
    • Journal of Intelligence and Information Systems
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    • v.23 no.4
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    • pp.147-168
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    • 2017
  • There have been many studies on accurate stock market forecasting in academia for a long time, and now there are also various forecasting models using various techniques. Recently, many attempts have been made to predict the stock index using various machine learning methods including Deep Learning. Although the fundamental analysis and the technical analysis method are used for the analysis of the traditional stock investment transaction, the technical analysis method is more useful for the application of the short-term transaction prediction or statistical and mathematical techniques. Most of the studies that have been conducted using these technical indicators have studied the model of predicting stock prices by binary classification - rising or falling - of stock market fluctuations in the future market (usually next trading day). However, it is also true that this binary classification has many unfavorable aspects in predicting trends, identifying trading signals, or signaling portfolio rebalancing. In this study, we try to predict the stock index by expanding the stock index trend (upward trend, boxed, downward trend) to the multiple classification system in the existing binary index method. In order to solve this multi-classification problem, a technique such as Multinomial Logistic Regression Analysis (MLOGIT), Multiple Discriminant Analysis (MDA) or Artificial Neural Networks (ANN) we propose an optimization model using Genetic Algorithm as a wrapper for improving the performance of this model using Multi-classification Support Vector Machines (MSVM), which has proved to be superior in prediction performance. In particular, the proposed model named GA-MSVM is designed to maximize model performance by optimizing not only the kernel function parameters of MSVM, but also the optimal selection of input variables (feature selection) as well as instance selection. In order to verify the performance of the proposed model, we applied the proposed method to the real data. The results show that the proposed method is more effective than the conventional multivariate SVM, which has been known to show the best prediction performance up to now, as well as existing artificial intelligence / data mining techniques such as MDA, MLOGIT, CBR, and it is confirmed that the prediction performance is better than this. Especially, it has been confirmed that the 'instance selection' plays a very important role in predicting the stock index trend, and it is confirmed that the improvement effect of the model is more important than other factors. To verify the usefulness of GA-MSVM, we applied it to Korea's real KOSPI200 stock index trend forecast. Our research is primarily aimed at predicting trend segments to capture signal acquisition or short-term trend transition points. The experimental data set includes technical indicators such as the price and volatility index (2004 ~ 2017) and macroeconomic data (interest rate, exchange rate, S&P 500, etc.) of KOSPI200 stock index in Korea. Using a variety of statistical methods including one-way ANOVA and stepwise MDA, 15 indicators were selected as candidate independent variables. The dependent variable, trend classification, was classified into three states: 1 (upward trend), 0 (boxed), and -1 (downward trend). 70% of the total data for each class was used for training and the remaining 30% was used for verifying. To verify the performance of the proposed model, several comparative model experiments such as MDA, MLOGIT, CBR, ANN and MSVM were conducted. MSVM has adopted the One-Against-One (OAO) approach, which is known as the most accurate approach among the various MSVM approaches. Although there are some limitations, the final experimental results demonstrate that the proposed model, GA-MSVM, performs at a significantly higher level than all comparative models.

The Effect of Technology-Based Entrepreneurship(TBE) Activities on Firms Growth (기술기반창업기업의 기업활동이 기업성장에 미치는 영향)

  • Lee, Myung-Jong;Joo, Youngjn
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.14 no.6
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    • pp.59-76
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    • 2019
  • Most technology-based entrepreneurship(TBE) go through an process of decline or disappear without overcoming the valley of death(VoD). The purpose of this study is to identify the growth dimension of TBE and to test the influence of firms activities on firms growth over time. This study identified the two-dimensional growth dimension divided by size and profit through exploratory factor analysis(EFA) of a number of growth indicators. Then, we defined the discrete state of growth firm in four states, divided by size and profit, and five states, including the closure of business. Multi-nomial logit model is used to predict the effect of TBE activities on a discrete state of growth firm(size×profit, closure of business) based on multiple independent variables. The independent variables are based on five representative firms activities: employment, marketing, R&D, financial activities, and general management activities. The growth stage of TBE over time has been categorized into three stages: early stage, middle stage, and late stage of business, taking into account the main periods during which the survival rate of startups sharply decreases. The analytical data of this study was based on the secondary data of the start-up supporting companies of government and public institutions. The subjects of analysis were TBE within 10 years. As a result of the empirical analysis, the employment and marketing activities of TBE show that early and mid-term activities had an effect on the state of firms growth. However, if there is a difference, employment activities have both positive and negative effects, while marketing activities have only a positive effect on size and profit growth. And besides, R&D activities, financial activities, and general management activities throughout the entire process of firms growth were found to be firms activities that have both positive and negative effects on firms growth. In addition, the age of the founder, the firms' industry, and the geographic location of the firms, which are general characteristics of the company, were found to have a distinctive effect on the growth status of the firms according to the growth stage.

A Dynamic Queue Manager for Optimizing the Resource and Performance of Mass-call based IN Services in Joint Wired and Wireless Networks (유무선 통합 망에서 대량호 지능망 서비스의 성능 및 자원 최적화를 위한 동적 큐 관리자)

  • 최한옥;안순신
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.25 no.5B
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    • pp.942-955
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    • 2000
  • This paper proposes enhanced designs of global service logic and information flow for the mass-call based IN service, which increase call completion rates and optimize the resource in joint wired and wireless networks. In order to hanve this logic implemented, we design a Dynamic Queue Manager(DQM) applied to the call queuing service feature in the Service Control Point(SCP). In order to apply this logic to wireless service subscribers as well as wired service subscribers, the service registration flags between the Home Location Register(HLR) and the SCP are managed to notify the DQM of the corresponding service subscribers’ mobility. Hence, we present a dynamic queue management mechanism, which dynamically manages the service group and the queue size based on M/M/c/K queueing model as the wireless subscribers roam the service groups due to their mobility characteristics. In order to determine the queue size allocated by the DQM, we simulator and analyze the relationship between the number of the subscriber’s terminals and the drop rate by considering the service increment rate. The appropriate waiting time in the queue as required is simulated according to the above relationship. Moreover, we design and implement the DQM that includes internal service logic interacting with SIBs(Service Independent building Blocks) and its data structure.

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Prediction of the Variation in Annual Biomass of White Croaker Argyosomus argentatus in Korean Waters using Leslie Matrix (한국 연근해 보구치, Argyrosomus argentatus의 Leslie Matrix에 의한 자원변동 예측)

  • LEE Sung Il;ZHANG Chang Ik
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.34 no.5
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    • pp.423-429
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    • 2001
  • Prediction of the variation in annual biomass was conducted for the white croaker. Argyrosomus argentatus in Korean waters using leslie Matrix, based upon fishery data for the past 21 years and biological data, We used density-independent and density-dependent Leslie Matrix models. Similar parameters were estimated from two models except that the density-dependent model was influenced by the density effect variable, q(i,t), The eigenvalue of the white croaker population for the $1984\~1995$ period was estimated to be 0.8, indicating a declining pattern of the population. The survival rate of 0-th year class was calculated to be 0.00005. Based on the schedule of the age-specific survival rate and fecundity, the future biomass and catch was predicted for various levels of fishing mortalities (F), If F was set at 0.252/yr ($F_{35x}$) or 0.368/yr ($F_{0.1}$), the biomass and catch increased, and if F was set at 0.922 ($F_{current}$), the biomass and catch decreased, The fishing mortality at equilibrium was estimated to be 0.7/yr. Finally, the management strategy of the white croaker was discussed.

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