• Title/Summary/Keyword: rate of resistance increase

Search Result 687, Processing Time 0.028 seconds

Relationship between Eradication of Helicobacter pylori Infection and Clarithromycin Resistance (Helicobacter pylori 감염의 치료와 Clarithromycin 내성간의 연관성)

  • Sohn Seung Ghyu;Lee Jong Hwa;Lee Jung Hun;Lee Sang Hee
    • Korean Journal of Microbiology
    • /
    • v.41 no.3
    • /
    • pp.177-182
    • /
    • 2005
  • H. pylori strains were isolated from antral biopsies taken during upper endoscopy in 114 dyspeptic patients with no previous therapy against H. pylori. Rapid urease test, PCR amplification of SSA and cagA gene for H. pylori detection, and Western blot for CagA expression detection were performed. H. pylori infected patients were treated with omeprazole, clarithromycin (a macrolide), and amoxicillin. At 6 weeks after the discontinuation of therapy, the bacterial eradication rate was determined by endoscopy. The resistance rate to clarithromycin and amoxicillin was $20.2\%$ and $0.0\%$, respectively. The clarithromycin resistance was mainly caused by the A2142G mutation in the 23S rRNA gene of H. pylori. MICs of clarithromycin for the A2142G mutant isolates were significantly higher than MICs for the A2143G mutant isolates. H. pylori eradication was obtained in all patients with clarithromycin-susceptible isolates but not in patients with clarithromycin-resistant isolates (P = 0.0001). These results did not appear to be biased by any differences in CagA expression. The resistance of H. pylori to clarithromycin included in the therapeutic regimens is the most important reason for treatment failure. H. pylori antimicrobial susceptibility testing of the gastric biopsy culture should be performed before choosing the first triple therapy in infected patients and the increase in prevalence of clarithromycin resistance in Korea was problematic.

Effects of Different Exercise Training Mode on Exercise Specificity and Transability (트레이닝 형태의 차이가 운동 특이성(exercise specificity)과 전사효과(transability)에 미치는 영향)

  • Kim, Young-Il;Kwak, Yi-Sub
    • Journal of Life Science
    • /
    • v.19 no.7
    • /
    • pp.968-975
    • /
    • 2009
  • The purpose of the present study was to examine effects of different exercise training modes (Aerobic Training, Resistance Training) on exercise specificity and transability. The tested subjects, composed of 10 healthy males without known family history or medical illnesses, were divided into two groups: Aerobic Training Group (ATG; n=5) and Resistance Training Group (RTG; n=5). An aerobic training program, based on maximum oxygen consumption rates taken during standard testing, was conducted in 60 minute sessions 3 times a week, and the Heart Rate Reserve (HRR) at 70% of maximum oxygen consumption rate was measured the using Polar. In the weight training program, based on repetition maximum rate (1-RM) taken during standard testing, the weight at 70% of such rates was measured during 60 minute sessions of 7 categories of exercise (Bench press, Leg press, Squat, Shoulder press, Arm curt Lat pull down, Triceps pull down), conducted 3 times a week. The data collected from this research were calculated to obtain average and differences compared to standards using an SPSS 11.0 statistics package. In conclusion, increase in V0$_{2max}$ and production of NO$_x$ (NO$_2$/NO$_3$), reduction of %fat, MAPwere shown effective in aerobic training and in different exercise tests, and aerobic testing within the aerobic training group (ATG) was shown to be more effective. In contrast, resistance training was shown to be more effective for the reduction of CK and LDH, and even in different tests, the resistance test within the resistance training group (RTG) showed to be more effective. Exercise specificity also significantly increased in both groups (ATG, RTG). but there was no significant difference in transability in both groups (ATG, RTG).

A Study on the Wearing Phenomenon of Pantograph Slider for the SEOUL METRO Line 4 Rail Vehicles (4호선 전동차 판토그라프 주습판 마모현상에 관한 연구)

  • Kim, Young-Gyu;Yang, Yong-Joon
    • Proceedings of the KSR Conference
    • /
    • 2007.11a
    • /
    • pp.51-56
    • /
    • 2007
  • Pantograph of the electric train is the important part receiving current by adhereing contact wire. Wearing rate of pantograph or contact wire is changed by the type of pantograph and material of adhering part. In special, the weather influences the relative wearing rate and wearing type of pantograph Slider and Contact wire with steep wearing in arc and life cycle of pantograph slider. Presently, the weather causes side-wearing and over-wearing of pantograph slide installed in electric train. So it is difficult to manage and operate the electric train. Although the quality of slide using in line4 vehicle was finished the test in line 2 vehicle experimentally, it has to apply after pantograph is installed in some electric trains and check the influence in it and contact wire. It is because line4 section is very different from line2 section. Experimental application is the sequence to certify the safety and abrasion resistance importantly by enlarging experimental application with increase of the experimental electric train. The lenth of line4 in Seoul Metro is 71.5[km]. It is long section. The line is mixed DC 1,500[V] section and AC 25,000[V] section. It has underground section of 41.5[km] and ground section of 30[km]. Ground section is about 42% and receives much influence in the rain during the rainy season. After experimental application we found that this pantograph slide has twice as much abrasion resistance despite a little deviation and found the occurrence probability of arc and side-wearing is decreased considerably.

  • PDF

Sliding Wear Behavior of AISI 52100 Steel with Pearlitic and Bainitic Microstructures (미세조직 변화에 따른 AISI 52100 강의 미끄럼마멸 특성)

  • Yoon, N.;Kim, Y.S.
    • Transactions of Materials Processing
    • /
    • v.20 no.7
    • /
    • pp.479-484
    • /
    • 2011
  • Dry sliding wear behavior of AISI 52100 steel that has a pearlite or bainite microstructure was characterized to explore the effect of microstructure on the wear of the steel. Isothermal heat treatments were employed to obtain the different microstructures. Pin-on-disk type wear tests of the steel disk were performed at loads of 25~125N in air against an alumina ball. Sliding speed and wear distance used were 0.1m/sec and 300m, respectively. Worn surfaces, wear debris and cross-sections of the worn surfaces were examined with SEM to investigate the wear mechanism of the steel. Hardness of the steel was also evaluated. Wear rate of the steel was correlated with the hardness and the microstructure. On the whole, wear resistance increased with an increase in hardness. However, the pearlite microstructure showed superior wear resistance as compared to the bainite microstructure with a similar hardness. The effect of the microstructure on the wear rate was attributed to the morphological differences of the carbide in the microstructure, which was found to have a significant effect on strain hardening during the wear.

Electrochemical behavior of Calcium Titanate Coated Ti-6Al-4V Substrate in Artificial Saliva

  • Lee, Byoung-Cheon;Balakrishnan, A.;Ko, Myung-Won;Choi, Je-Woo;Park, Joong-Keun;Kim, Taik-Nam
    • Korean Journal of Materials Research
    • /
    • v.18 no.1
    • /
    • pp.22-25
    • /
    • 2008
  • In this study, calcium titanate $(CaTiO_3)$ gel was prepared by mixing calcium nitrate and titanium isopropoxide in 2-methoxy-ethanol. $CaTiO_3$ gel was single-layer coated on Ti-6Al-4V using a sol-gel dip-coating technique. The coating was calcined at $750^{\circ}C$ in air by utilizing a very slow heating rate of $2^{\circ}C/min$. The crystalline phases of the coating were characterized by x-ray diffraction using a slow scan rate of $1^{\circ}/min$. The morphology of the coating was analyzed by scanning electron microscopy. The corrosion behavior of Ti-6Al-4V samples coated with $CaTiO_3$ films were tested in an artificial saliva solution by potentiodynamic polarization and were quantified by the Tafel extrapolation method. The electrochemical parameters showed a considerable increase in the corrosion resistance for the $CaTiO_3$-coated Ti-6Al-4V samples compared to bare substrates.

Study on the Heat Generation Characteristics of the Carbon Heating Source with High Temperature (고온 카본발열체의 발열특성에 관한 연구)

  • Bae, K.Y.;Lee, K.S.;Shin, J.H.;Jeong, H.M.;Chung, H.S.;Chun, J.S.
    • Proceedings of the KSME Conference
    • /
    • 2001.11b
    • /
    • pp.106-111
    • /
    • 2001
  • This paper is a study on the heat generation characteristics of the carbon heating source with high temperature. The main variables of this study are the input current and the amount of carbon heating source. As the results of the experiment in the waste rate of carbon heating source. The case of carbon heating source 300g was large than 500g. As the input current and the temperature are increased, the resistance values of carbon heating source were large. The Joule heat was represented the large value as the amount of heating source decrease with the input current. Finally, the heating source was represented the electrical steady state as the input current is increase.

  • PDF

Electrical Properties of PET(polyethylene teraphthalate) by Ion Implantation (이온주입에 의한 PET(polyethylene teraphthalate)의 표면결합상태 변화와 표면전기전도도 특성)

  • 이재형;길재근
    • The Transactions of the Korean Institute of Electrical Engineers C
    • /
    • v.53 no.7
    • /
    • pp.382-386
    • /
    • 2004
  • A study has been made of surface modification of organic materials by ion implantation to increase the surface electrical properties. The substrate used were PET(polyethylene teraphtalate). N$^{+}$, Ar$^{+}$ implantation was peformed at energies of 40 keV and 50 keV with fluences from $5{\times}10^{15}$, $1{\times}10^{16}$,$7{\times}10^{16}$, $1{\times}10^{17}$/ ions/$cm^2$. UV/Vis, FT-IR and XPS spectroscopy measured for surface structure changes. Surface resistance decrease of implanted polymers was affected by ion implantation energy, ion species and ion dose rate. Surface conductivity of PET increased $2{\times}10^{9}$/∼$2{\times}10^{10}$/$\Omega$/sq by ion implantation. Result of various spectroscopy analysis, the cause of increasing PET surface conductivity was expected to breaking C=O bonds. It was formation carbon network structure by promote cross-linking and create C-C, C=C bonds.

A Study on the Surface Analysis of Plasma-Treated PET Film (플라즈마 처리된 PET 필름의 표면분석에 관한 연구)

  • Lim Kyung-Bum;Choi Hoon-Young;Lee Seok-Hyun;Lee Duck-Chool
    • The Transactions of the Korean Institute of Electrical Engineers C
    • /
    • v.53 no.12
    • /
    • pp.596-600
    • /
    • 2004
  • In this study, the surface properties of PET film were analyzed after plasma surface treatment. After plasma treatment of surface roughness and XPS were evaluated to analyze the chemical property, while the surface potential decay and surface resistance rate was measured to analyze the electric관 characteristic. When plasma discharge treatment was conducted for less than 10 minutes, the electrical insulating property was improved by evaporation of low molecular weight materials and cleaning of surface. However, when the treatment was conducted for more than 10 minutes, the insulating property was decreased due to excessive discharge energy. Analyses of chemical characteristics showed that 10-minute treatment resulted in increase of C-O and O=C-O bonds. However, when treated for more than 10 minutes. they were relatively decreased.

Effect of Stress Ration on Fatigue Crack Propagation Behavior of Pressure Vessel Steel SA516-Grade70 at Higt Temperature. (원자로 압력용기용 강의 고온피로특성에 미치는 응력비의 영향)

  • 박경동;정찬기;김정호
    • Journal of Advanced Marine Engineering and Technology
    • /
    • v.25 no.5
    • /
    • pp.1108-1114
    • /
    • 2001
  • The fatigue crack propagation behavior of the SA516-Grade 70 steel which is used for pressure vessels was experimentally examined under the condition of at room temperature, $150^{\circ}C$, $250^{\circ}C$ and $370^{\circ}C$ with stress ration of R=0.1 and 0.3. The fatigue crack propagation rate , da/dN, related with the stress intensity factor range, $\vartriangle$N, was influenced by the stress ration within the stable growth of fatigue crack(Region II) with an increase in $\vartriangle$N. The resistance to the fatigue crack growth at high temperature is higher in comparison with that at room temperature, and the resistance attributed to the extent of plasticity-induced by compressive residual stress according to the cyclic loads. Fractographic examinations revels that the differences of the fatigue crack growth characteristics between room and high temperatures are mainly explained by the crack and oxide-induced by high temperature.

  • PDF

Effect of Tempering Temperature on Hydrogen Embrittlement of Cr-Mo Low Alloy Steels for High-pressure Gaseous Hydrogen Storage (고압수소 저장용 Cr-Mo계 저합금강의 수소취성에 미치는 템퍼링 온도의 영향)

  • M. S. Jeong;H. C. Shin;S. G. Kim;B. Hwang
    • Transactions of Materials Processing
    • /
    • v.33 no.3
    • /
    • pp.185-192
    • /
    • 2024
  • This study examined how varying tempering temperatures affect the susceptibility of Cr-Mo low alloy steels to hydrogen embrittlement. A slow strain-rate test (SSRT) was carried out on the steels electrochemically pre-charged with hydrogen in order to examine the hydrogen embrittlement behavior. The results showed that the hydrogen embrittlement resistance of the Cr-Mo low alloy steels improved with increasing tempering temperature. Thermal desorption analysis (TDA) revealed that diffusible hydrogen content decreased with increasing tempering temperature, accompanied by a slight increase in the peak temperature. This decrease in hydrogen content was likely due to a reduction in dislocation density which served as reversible hydrogen trap sites. These findings underline the significant role of tempering temperature in enhancing the hydrogen embrittlement resistance of Cr-Mo low alloy steels.