• Title/Summary/Keyword: rate constant(k)

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The Effect of Doxapram on Cardiopulmonary Function in Dogs under Total Intravenous Anesthesia with Remifentanil and Propofol (개에서 Remifentanil과 Propofol에 의한 완전 정맥 내 마취 시 Doxapram 투여가 심폐기능에 미치는 효과)

  • Yun, Sungho;Kwon, Youngsam
    • Journal of Veterinary Clinics
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    • v.32 no.6
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    • pp.491-498
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    • 2015
  • We investigated the effect of constant rate infusion (CRI) with doxapram on cardiopulmonary function during total intravenous anesthesia (TIVA) with remifentanil and propofol CRI in dogs. Fifteen male Beagle dogs were randomly divided into 3 groups. All groups were premedicated with medetomidine ($20{\mu}g/kg$, IV) and anesthetized by remifentanil/propofol CRI for one and half hour. At the initiating of the anesthesia, different doses of doxapram for each group were administrated as the followings; D1 group - doxapram 0.25 mg/kg bolus followed by doxapram $8.33{\mu}g/kg/min$, D2 group - doxapram 2 mg/kg bolus followed by doxapram $66.66{\mu}g/kg/min$, control group - normal saline. The anesthetic depth for surgery was well maintained in all groups throughout the anesthetic periods. The respiratory rate was significantly higher in D2 group than that of control group (p < 0.05). The values of $PaO_2$ and $SaO_2$ were significantly increased in both D1 and D2 groups compared with control group (p < 0.05). High dose of doxapram (D2 group) significantly decreased the level of $PaCO_2$ compared with control group (p < 0.05). The values of systolic, mean and diastolic arterial pressure were significantly increased in doxapram 2 group (p < 0.05). There were no significant differences in the values of heart rate and pH of arterial blood. Therefore, doxapram CRI may be useful to alleviate the suppression of cardiopulmonary function including hypoxia and hypotension during TIVA with remifentanil and propofol in dogs.

Kinetic Studies on the Thermal Degradation of Ginsenosides in Ginseng Extract (Ginsenosides의 처리온도(處理溫度) 및 시간(時閭)에 따른 반응속도론적(反應速度論的) 연구(硏究))

  • Choi, Jin-Ho;Kim, Doo-Ha;Sung, Hyun-Soon;Kim, Woo-Jung;Oh, Sung-Ki
    • Korean Journal of Food Science and Technology
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    • v.14 no.3
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    • pp.197-202
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    • 1982
  • Kinetic study for the thermal degradation of ginsenosides in ginseng extract was conducted. The results indicate that the thermal degradation followed first order kinetics and rate constants varied substantially depending on the types of ginsenosides and heat treatment temperatures. Activation energy calculated by Arrhenius plots ranged from 16.80 kcal/mole to 30.10 kcal/mole and $Q_{10}$ values ranged from 2.01 to 3.49. Correlation coefficients between the change of ginsenoside contents by thermal degradation and heat treatment temperature were $0.995{\sim}0.999$. The dependence on temperatures of the decomposition rate constant of total ginsenoside can be expressed as $k=4.574{\times}10^8$ exp(8898.8/T).

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Cell Growth and Lipid Production from Fed-batch Cultivation of Chlorella minutissima according to Culture Conditions (유가식 배양에서 배양조건에 따른 Chlorella minutissima의 생육 및 지질생산)

  • Oh, Sung-Ho;Han, Jae-Gun;Kim, Na-Young;Cho, Jeong-Sub;Yim, Tae-Bin;Lee, Shin-Young;Lee, Hyeon-Yong
    • KSBB Journal
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    • v.24 no.4
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    • pp.377-382
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    • 2009
  • The culture condition of growing Chlorella minutissima was optimized to produce biodiesel for fed-batch cultivation. First, under heterotrophic cultivation, the optimum level of glucose was determined to be 10 g/L for 20 days. After, three cultivation conditions were operated: autotrophic, heterotrophic, and mixotrophic growth. The lipid level and the maximum cell concentration from the fed-batch heterotrophic process were 32.0 (%, v/v) and 15.0 (g-dry wt./L) in 20 L flask, respectively. In addition, since the relatively constant specific lipid production rate was observed as 0.040 (% lipid/g-dry wt./day) at the latter period of cultivation time, the fed-batch process could maintain continuous lipid production. Fed-batch process is higher than those values from the batch process. The lipids from the fed-batch process contained over 38% of $C_{18}$, known as the suitable composition for the biodiesel application. For mixotrophic and heterotrophic growth under fed-batch condition, glucose was proved to be an appropriate carbon source for a large scale outdoor cultivation. For fed-batch cultivation, the feeding rate of seawater medium containing glucose was decided to be 0.5 L/day. The mixotrophic cultivation maintained maximum cell concentration of 24 (g-dry wt./L) and the lipid level of 43 (%, w/w). The lipid composition from this process was also proved to be suitable for the biodiesel production. The fatty acids from the mixotrophic growth contains 18% of $C_{17}$ and 49% of $C_{18}$, implying It also tells that C. minutissima is a suitable resource of biodiesel. Especially, the mixotrophic cultivation with fed-batch process might be useful for the large scale cultivation for the biodiesel production.

Study on Characteristic of CO2 Hydrate Formation Using Micro-sized Ice (미세직경 얼음을 이용한 CO2 하이드레이트 제조특성 연구)

  • Lee, Jong-Hyub;Kang, Seong-Pil
    • Korean Chemical Engineering Research
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    • v.50 no.4
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    • pp.690-695
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    • 2012
  • Gas hydrate is an inclusion compound consisting of water and low molecular weight gases, which are incorporated into the lattice structure of water. Owing to its promising aspect to application technologies, gas hydrate has been widely studied recently, especially $CO_2$ hydrate for the CCS (Carbon Capture and Storage) issue. The key point of $CO_2$ hydrate technology for the CCS is how to produce gas hydrate in an efficient and economic way. In this study, we have tried to study the characteristic of gas hydrate formation using micro-sized ice through an ultrasonic nozzle which generate 2.4 MHz frequency wave. $CO_2$ as a carrier gas brings micro-sized mist into low-temperature reactor, where the mist and carrier gas forms $CO_2$ hydrate under $-55^{\circ}C$ and atmospheric pressure condition and some part of the mist also remains unreacted micro-sized ice. Formed gas hydrate was average 10.7 of diameter at average. The starting ice particle was set to constant pressure to form $CO_2$ hydrate and the consumed amount of $CO_2$ gas was simultaneously measured to calculate the conversion of ice into gas hydrate. Results showed that the gas hydrate formation was highly suitable because of its extremely high gas-solid contact area, and the formation rate was also very high. Self-preservation effect of $CO_2$ hydrate was confirmed by the measurement of $CO_2$ hydrate powder at normal and at pressed state, which resulted that this kind of gas storage and transport could be feasible using $CO_2$ hydrate formation.

A Study on Improving Pitch Search for Vocoder (보코더에서 피치검색 성능개선에 관한 연구)

  • Baek, Geum-Ran;Bae, Myung-Jin
    • The Journal of the Acoustical Society of Korea
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    • v.31 no.7
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    • pp.419-426
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    • 2012
  • The pitch searching is a vital process in a vocoder. Generally, the method of pitch searching is employed after highlighting the periodicity, where a correlation is identified with the signal by changing the interval of two pulses. When the correlation value reaches the peak, the pitch can be found by the pulse interval because it is the repetition interval with most striking period. However if the identified period happens to be one of half period, double period or triple period, this cannot be considered as the pitch period. Many methods were suggested to solve this problem. An inaccurate pitch could be obtained as well, when there is an interval where signal amplitude is not constant but varies abruptly in the frame. To solve this matter, searching the pitch by dividing a frame into various subframes is adopted, but too much calculation has to be followed while it leads the correct value. This paper suggests an algorithm to resolve these two problems. First, to search the pitch after advance correction of the signal energy level with an estimated overall energy change ratio in the frame before pitch search to reduce half period, double period and triple period is suggested. Second, to vary the number of subframes by predicting the amplitude change rate in the frame by the energy ratio obtained by the above-mentioned method is advised. If these two methods are applied, the pitch searching time can be reduced and the general pitch searching performance can be improved without affecting the sound quality in the synthesized signal.

The Concentrating Photovoltaic System using a Solar Tracker (태양위치 추적 장치를 이용한 집광형 태양광 발전시스템)

  • Yoo, Yeong-tae;Na, Seung-kwon
    • Journal of Advanced Navigation Technology
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    • v.21 no.4
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    • pp.377-385
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    • 2017
  • The solar cell need the characteristic interpreting because the solar cell changes greatly according to the isolation, temperature and load in the photovoltaic development. Moreover, to get many energy in photovoltaic development need the position tracking of the sun according to the environment change. Also, The solar cells should be operated at the maximum power point. In this paper, I used microprocessor and sensor and designed to improve the efficiency of the photovoltaic system the photovoltaic position tracker device, and compared the normal photovoltaic system of fixed form with the photovoltaic system of solar position tracked form. Moreover, compared the catalogue of solar cell module and the simulation through a mathematics modelling with the solar cell's characteristic interpreting and composed an power conversion system with boost converter and voltage source inverter. Used the constant voltage control method for maximum power point tracking in boost converter control and, used the SPWM(Sinusoidal Pulse Width Modulation) control method in inverter control. The result was less then 5% when compared the catalogue of solar cell module and the simulation through a mathematics modelling. The boost rate of boost converter was similar to 167 % with the simulation.

Development of an Analytical Model of BOD(AMB) for Total Pollution Load Regulation (오염총량관리를 위한 분석적 BOD모델(AMB) 개발)

  • Kim, Gyeong-Seop;An, Tae-Jin
    • Journal of Korea Water Resources Association
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    • v.33 no.6
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    • pp.775-782
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    • 2000
  • Water quality models can be applied to manage the regional water quality problems and to estimate the target and allowable pollution load in watershed effectively. Since the models such as QUAL2E, W ASP5 and HSPF need many data and are not easily applied in real systems, the water quality model, which would be simple and easily applicable, has been required. Thus, an Analytical Model of BOD(AMB) considering travel time of pollutant was developed for the total pollution load regulation in drainage basin. It was found that the main stream length of a sub-basin in the AMB should be shorter than 7km and the length of distributed pollutant load should also be shorter than 3.5km in a sub-basin. The basin in the AMB could be divided into sub-basins with almost same hydraulic characteristics and reaction rate constant satisfying the proposed stream length. The running results of the AMB in a small stream were very close to the results of QUAL2E, which is widely used one in the world. Therefore, the AlVIB can be used to regulate the total pollution load in drainage district by local government.rnment.

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Reduction of Hydraulic Conductivity in the Subsurface by the Formation of Aerobic Biobarrier (토양 내 호기성 생물벽체(Biobarrier)의 형성에 의한 투수계수의 제어)

  • Bae, Bum-Han;Oh, Je-Ill
    • Journal of Soil and Groundwater Environment
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    • v.12 no.2
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    • pp.1-8
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    • 2007
  • A series of batch and column experiments were conducted for the development of biobarrier technology which can be applied to containment and reduction of contaminants in soil and ground waters. The growth kinetic constants of Pseudomonas fluorescens on glucose or molasses were determined using batch experiments. The maximum specific growth rate (Vmax) of P. fluorescens at $23^{\circ}C$ on glucose or molasses were $0.246\;hr^{-1}$ and $0.073\;hr^{-1}$, respectively. However, molasses was selected as carbon source due largely to the absence of lag phase of P. fluorescens growth on molasses and economic reason. In constant head column experiments, the hydraulic conductivity of the column soil reduced by $6.8{\times}10^{-3}$ times from $4.1{\times}10^{-2}cm/sec$ to $2.8{\times}10^{-4}cm/sec$ after the inoculation of P. fluorescens and administration of carbon source and nutrients. The biomass concentration was observed highest in the column inlet. Measurements of carbon source and electron accepter (dissolved oxygen) concentration showed that the growth of P. fluorescence, which is the main reason for hydraulic conductivity reduction, was limited not by the concentration of carbon source but by the concentration of electron acceptor.

Comparison of Annual Maximum Rainfall Series and Annual Maximum Independent Rainfall Event Series (연최대치 계열과 연최대치 독립 호우사상 계열의 비교)

  • Yoo, Chul-Sang;Park, Cheol-Soon
    • Journal of Korea Water Resources Association
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    • v.45 no.5
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    • pp.431-444
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    • 2012
  • This study investigated the differences between annual maximum series and annual maximum independent rainfall event series with relatively short and long rainfall durations. Annual maximum independent rainfall events were selected by applying various IETDs and thresholds to the hourly rainfall data in Seoul for the duration from 1961 to 2010. Annual maximum independent rainfall event series decided were then compared with the conventional annual maximum series. Summarizing the results is as follows. First, the effect of IETD and threshold was not beyond the expected level. For example, as the IETD increases, the frequencies of independent rainfall events decreased similarly in their rate for both with short and long durations. However, as the threshold increases, the frequency of those with rather long durations decreased much higher. Second, The mean rainfall intensity of the independent rainfall events was found to remain constant regardless of their duration. This indicates that the annual maximum rainfall intensity could be found in a rainfall event with longer durations. Lastly, the difference between the annual maximum rainfall series and the annual maximum independent rainfall event series with rather short rainfall durations was found significantly large, which decreases with longer durations. This result indicates that the conventional data analysis method, especially for small basins with short concentration time, could lead an unrealistic design rainfall with little possibility of occurrence.

Aging Effects on Sorption and Desorption of Atrazine in Soils (Atrazine의 토양 흡착 및 탈착에 미치는 접촉시간의 영향)

  • Park Jeong-Hun
    • Journal of Soil and Groundwater Environment
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    • v.10 no.1
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    • pp.26-34
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    • 2005
  • The effects of soil-chemical contact time (aging) on sorption and desorption of atrazine were studied in soil slurries because aging is an important determinant affecting on the sorption and desorption characteristics of organic contaminants in the environment. Sorption isotherm and desorption kinetic experiments were performed, and soilwater distribution coefficients and desorption rate parameters were evaluated using linear and non-linear sorption equations and a three-site desorption model, respectively. Aging time for sorption of atrazine in sterilized soil slurries ranged from 2 days to 8 months. Atrazine sorption isotherms were nearly linear $(r^2\;>\;0.97)$ and sorption coefficients were strongly correlated to soil organic carbon content. Sorption distribution coefficients $(K_d)$ increased with increasing aging in all soils studied. Sorption non-linearity did not increase with increased aging except for the Houghton muck soil. Desorption profiles were well described by the three-site desorption model. The equilibrium site fraction $(f_{eq})$ decreased and the non-desorbable site fraction $(f_{nd})$ increased as a function of aging time in all soils. In all soils studied, it was found that when normalized to soil organic matter content the concentration of atrazine in desorbable sites was comparatively constant, whereas that in non-desorbable site increased as aging increased.