• 대한핵의학회:학술대회논문집
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• 대한핵의학회 1999년도 제38차 춘계학술대회
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• pp.200-204
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• 1999

Rheumatoid arthritis (RA) is o chronic inflammatory disease of joints with proliferation of synovial epithelial tissue. Therapeutic approach of the RA consists of pharmacological and surgical interventions. Synovectomy is indicated in patients with progressive inflammatory signs and symptoms intractable to medical treatment including local intracavitary steroid injection. Recently, local injection of radionuclides which emit high energy beta rays are labeled with chemical compounds such as $^{90}Y,\;^{165}Dy-ferric$ hydroxide macroaggregate and have been introduced as an alternative therapeutic modality to surgical synovectomy. Holmium-166 is one of beta emitter and Ho-166-chitosan complex was developed for radiation synovectomy. Preclinical trial is on-going at our hospital using Ho-166-chitosan. The procedure and methods of preclinical trial are discussed.

• Asian Pacific Journal of Cancer Prevention
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• 제15권4호
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• pp.1503-1510
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• 2014

Breast cancer bone metastasis causing severe morbidity is commonly encountered in daily clinical practice. It causes pain, pathologic fractures, spinal cord and other nerve compression syndromes and life threatening hypercalcemia. Breast cancer metastasizes to bone through complicated steps in which numerous molecules play roles. Metastatic cells disrupt normal bone turnover and create a vicious cycle to which treatment efforts should be directed. Bisphosphonates have been used safely for more than two decades. As a group they delay time to first skeletal related event and reduce pain, but do not prevent development of bone metastasis in patients with no bone metastasis, and also do not prolong survival. The receptor activator for nuclear factor ${\kappa}B$ ligand inhibitor denosumab delays time to first skeletal related event and reduces the skeletal morbidity rate. Radionuclides are another treatment option for bone pain. New targeted therapies and radionuclides are still under investigation. In this review we will focus on mechanisms of bone metastasis and its medical treatment in breast cancer patients.

• Nuclear Engineering and Technology
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• 제34권5호
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• pp.415-420
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• 2002

The previous dynamic food chain model was improved for the consideration of the influence of radioactive contamination to agricultural products due to rain during the environmental releases of radionuclides in a nuclear accident Wet interception coefficients for the agricultural plants were derived as a function of radionuclide and rainfall amount, and mathematical formulations of the previous model were modified. As a result, rain during accidental releases was influential in agricultural contamination. The contamination level of agricultural products decreased dramatically according to increasing rainfall amount. It means that predictive concentrations in agricultural products using the previous model, in which dry interception to the agricultural plants is only considered, can be overestimated. The influence of rainfall in agricultural contamination was the most sensitive for $^{131}$ I, and the least sensitive for $^{90}$ Sr among the radionuclides considered in this study.

• KSBB Journal
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• 제27권5호
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• pp.281-288
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• 2012

Phytoremediation-the use of plants for the in situ treatment of contaminated soil and water-has recently emerged as an inexpensive and user-friendly alternative to traditional methods of environmental clean-up. The present article outlines the characteristics of phytoremediation based on accumulated research evidence, along with discussions on its advantages and disadvantages. It further reviews various mechanisms involved in the phytoremediation processes: phytoextraction, rhizofiltration, phytostabilization, phytovolatilization and phytodegradation. Along the way, the author summarizes examples of its applications to environmental pollution control. These include wastewater treatment, removal of heavy metals, and hydrocarbons, remediation of recalcitrant contaminants, phytoremediation of radionuclides, and application of transgenic plants for enhanced biodegradation and phytoremediation. The remainder of the article briefly concludes with directions for future research.

• 대한방사선기술학회지:방사선기술과학
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• 제9권1호
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• pp.65-71
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• 1986

It is an experimental report about optimum window-width on radionuclides $^{99m}Tc$ and $^{131}I$ and obtained results as follows; 1. In case of $^{99m}Tc$, a) The difference of counting rate in each window-width is greater at the below 20% window than above 20% window-width. b) BKG counting is proportionated to the window-width. 2. In case of $^{131}I$, a) The counting rate increased according to the window-width but the increasing course is not equal in all window. The difference of counting rate is greater at the below of 20% window-width than above 20% window. b) BKG counting is proportionated to the window-width.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2005년도 춘계 학술대회
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• pp.49-55
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• 2005

Unconditional clearance levels were derived for fifteen short-lived radionuclides. Due to the uncertainty of long-term radiological impact analysis, alpha emitting nuclides and nuclides with half-lives longer than 30 years (except for C-14) were excluded from the scope of this study. The candidate waste streams are solid wastes and waste oil generated from nuclear power reactors. The clearance levels were derived by generic assessment for enveloping scenarios, along with specific assessment for each detailed scenario such as landfill, incineration and recycling. The derived values lie in the range from 0.01 to 100 Bq/g.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 1995년도 추계학술발표회논문집(2)
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• pp.879-884
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• 1995

The results of performance assessment analyses have shown that the long-lived radionuclides such as I-129 control the potential individual dose impact to the public. I-129 is difficult-to-measure(DTM) in low-level waste because it is non-gamma emitting radionuclides and exists at extremely low concentrations in radioactive waste generated by nuclear reactors. In this study, computer modeling technique to predict release rate of I-129 is developed to provide another tools far performance assessment of land disposal facilities and characteristics of radwaste. Model suggested in this study will give conservative values of I-129 release rate far determination of radwaste characteristics. More detailed approach is implemented to account for release conditions of fuel source-nuclides. 1-131 concentration measured from reactor coolant and released fraction from tramp fuel have dominant roles in calculating release rate of I-129 with fuel defect conditions.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2018년도 춘계학술논문요약집
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• pp.183-183
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• 2018

In this study, 5-bromo-2,9-bis(5,6-diphenyl-1,2,4-triazin-3-yl)-1,10-phenanthroline (5-bromo-Ph4-BTPhen) was synthesized and evaluated for its ability to remove major radionuclides ($Cs^+$, $Sr^{2+}$, and $Co^{2+}$). The synthesized ligand removed both $Sr^{2+}$ and $Co^{2+}$ from $1mg\;L^{-1}$ aqueous solutions with extraction efficiencies of up to 99% at neutral and alkaline pH. The $Sr^{2+}$ and $Co^{2+}$ removal efficiencies decreased as a consequence of the higher bonding strengths of competing metal ions to the N-donor atoms in the cavity of the ligand; competing divalent ions affected the $Sr^{2+}$ and $Co^{2+}$ removal efficiencies more than monovalent ions.

• Nuclear Engineering and Technology
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• 제53권9호
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• pp.2918-2925
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• 2021

The efficiency of decontamination of model spent ion exchange resins, contaminated with magnetite and hematite, with mineral acid solutions, and using electro-decontamination, was evaluated. It has been shown that effective hematite dissolution occurs in concentrated mineral acid solutions. However, the use of direct current increases the decontamination efficiency of spent ion exchange resins contaminated with hematite. It is determined that with increasing voltage and acid concentration, the dissolution efficiency of hematite deposits increases and can exceed 99%. It has been shown that hematite dissolution is accompanied by secondary adsorption of radionuclides due to ion exchange, which can be removed with sodium nitrate solutions.

• Nuclear Engineering and Technology
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• 제56권4호
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• pp.1250-1253
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• 2024

Activity measurement of the primary circuit water of fission reactors is one method that can provide early detection of a damaged fuel assembly in the reactor core. This is an important aspect in the safe operation of the reactor and for radiation protection of staff. Radionuclides in the primary circuit water are produced by the activation of stable nuclides and the fission of fissile nuclides, mainly the isotope ²³⁵U. In the LVR-15 research reactor, measurement of the activity of the primary circuit water has been regularly undertaken since 1996. A water sample is taken from the primary circuit every week and the activities are measured four days later using gamma spectrometry. The results of these long-term measurements from 1996 to 2022 are presented. The activity time dependences of the individual radionuclides are discussed in relation to fuel assembly damage and for events connected to contamination of the water by objects inserted into the primary circuit during experiments carried out near the reactor core.