• Title/Summary/Keyword: radiological science

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Reduction of Radiation Dose according to Geometric Parameters from Digital Coronary Angiography (디지털 심혈관조영장치의 기하학적 특성에 따른 선량 감소)

  • Kang, Yeonghan;Cho, PyongKon
    • Journal of the Korean Society of Radiology
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    • v.7 no.4
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    • pp.277-284
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    • 2013
  • This study aims to find out geometric parameters which practitioner adjustable to reduce dose in coronary angiography. We take fluoroscopy and cine exposure by use of phantom, and got dose use the dose-area product(DAP) meter of angiography device, than convert DAP to effective dose. As results, Cine exposure shows higher dose measurement about 6-7 times than fluoroscopy. Dose in frame per second(FPS) mode could be decrease down to 70%, as lower FPS. In view of X-ray tube angle, LAO $45^{\circ}$+Caudal $30^{\circ}$ shows highest dose measurement. More use of Collimator, lower dose measurement. Source-image intensifier distance(SID) get longer to 10cm, dose of each fluoroscopy and cine exposure increase up to 25-30%. Image magnification of field of view(FOV) could increase dose up to 1.21-2 times. Also table-image intensifier distance get longer to 10cm, dose increased 1.11-1.25 times. Practitioner can adjust several geometric parameters, as FPS mode, tube angle, Collimation, SID, table-image intensifier distance, FOV. And each factors can reduce radiation dose in coronary angiography.

The usability of the MR Breast perfusion image and Time-Signal Intensity curve in Breast cancer patients (유방암 환자에서 MR Breast perfusion 영상과 시간-신호강도 곡선의 유용성)

  • Cho, Jae-Hwan;Lee, Hae-Kag
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.9
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    • pp.4068-4074
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    • 2011
  • The purpose of this study was to examine the usefulness of MR Breast perfusion image and time-signal intensity curve in patients diagnosed with breast cancer. We selected on 20 patients who were histologically diagnosed to have invasive ductal carcinoma (IDC) from March 2009 to December 2010. First, the Breast perfusion mapping image was reconstructed after obtaining the dynamic contrast enhancement image. The reconstructed image measured the slope, maximal relative enhancement, and time to peak on the detail including the lesion region, normal region, back ground region after obtaining the time-signal intensity curve. The lesion region and normal and slope of the back ground part were measured with the quantitive analytical method about the research and the average was compared and was analyze. In the qualitative analysis, the signal strength of each pixel was analyze with the macroscopic and being high it was low, the medium (2) performed the division of (a) by the three-point standard and the average was measured. The findings from the quantitative image analysis are the following: In the lesion region, the slope and maximal relative enhancement were the highestest among and the time to peak was the highestest in the back ground region. In the qualitative analysis, the breast perfusion image showed a diagnostic efficiency.

The Distribution of $^{14}C-chitosan$ by Different Molecular Weight in Mice (마우스에서 $^{14}C-chitosan$ 분자량별 체내 분포에 관한 연구)

  • Kim, Kwang-Yoon;Kim, Young-Ho;Kim, Hee-Kyung;Bom, Hee-Seung;Kim, Ji-Yeul;Roh, Young-Bok;Nishimura, Yoshikazu
    • Journal of Radiation Protection and Research
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    • v.23 no.2
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    • pp.83-88
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    • 1998
  • Chitosan is a nontoxic natural chealtor which was made by chitin, and reduced a contamination of radiostrontium in animals. In this experiment, A different molecular weight of C-14 chitosan was intravenously administered to mice, and then the distribution of C-14 chitosan in the body was observed. Male mice (8 to 10 weeks, body weight of 30 to 35g) of ICR strain were used. C-14 chitosan was diluted with saline and then given intravenously in mice. After the administration of C-14 chitosan, mice was sacrificed at the 6th hour, 1st, 3rd, 5th, and 7th day. Beta radioactivities in the blood, liver, kidney, liver, muscle, testis, and urine was measured using a liquid scintillation analyzer. Most of the C-14 chitosan was excreted through urine within 6 hours. Biodistribution of C-14 chitosan was similar despite the difference of moleclar weight. Higher distributions of radioactivities were found in the liver, kidney, spleen. The relative concentration in tissue increased for the 6 hours and then decreased. In conclusion, most of C-14 chitosan was excreted through urine despite the difference of molecular weight. and, low molecular weight of C-14 chitosan showed higher distribution than high molecular weight of C-14 chitosan in tissues.

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Evaluation of Dose and Image Quality of Lens according to Baseline during Brain CT Scan (두부 전산화단층촬영 시 기준선에 따른 수정체 선량과 화질 평가)

  • Kim, Kyu-Hyung;Kim, Sang-Hyun
    • Journal of the Korean Society of Radiology
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    • v.13 no.5
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    • pp.699-704
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    • 2019
  • It is important to minimize the exposure dose during an examination and obtain good quality images at the same time. This study compared the beam harding effect according to the baseline superior orbito meatal line(SOML), orbito meatal line(OML), inferior orbito metal line(OML) and measured the exposure dose of the lens, especially in brain CT examinations, which generally apply to head diease patients. The beam harding effect assessment of each image along the baseline was performed quantitatively using the Image J program, and the exposure dose of the lens was detected by OSLDs and compared. As a result, As a result, when the SOML was used as the reference line, the dose of the lens was decreased by 85.08% at 80 kV and by 79.7% at 80 kV, compared to when IOML was used as the baseline. If the gantry angle at brain CT was parallel scan to SOML, there were no significant differences in the exposure to the lens and between the OML and IOML. Therefore, this study has shown that it is efficient to have a parallel scan on SOML as a protocol during Brain CT examinations.

Characterization of Physical Processes and Secondary Particle Generation in Radiation Dose Enhancement for Megavoltage X-rays (MV X선의 방사선 선량 증강 현상에서 물리적 특성과 이차입자의 발생)

  • Hwang, Chulhwan;Kim, JungHoon
    • Journal of the Korean Society of Radiology
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    • v.13 no.5
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    • pp.791-799
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    • 2019
  • We evaluated the physical properties that occur to dose enhancement and changes from secondary particle production resulting from the interaction between enhancement material. Geant4 was used to perform a Monte Carlo simulation, and the medical internal radiation dose (MIRD) head phantom were employed. X-rays of 4, 6, 10, 15, 18, and 25 MV were used. Aurum (Au) and gadolinium (Gd) were applied within the tumor volume at 10, 20, and 30 mg/g, and an experiment using soft tissue exclusively was concomitantly performed for comparison. Also, particle fluence and initial kinetic energy of secondary particle of interaction were measured to calculate equivalent doses using the radiation weight factor. The properties of physical interaction by the radiation enhancement material showed the great increased in photoelectric effect as compared to the compton scattering and pair production, occurred with the highest, in aurum and gadolinium it is shown in common. The photonuclear effect frequency increased as the energy increased, thereby increasing secondary particle production, including alpha particles, protons, and neutrons. During dose enhancement using aurum, a maximum 424.25-fold increase in the equivalent dose due to neutrons was observed. This study was Monte Carlo simulation corresponds to the physical process of energy transmission in dose enhancement. Its results may be used as a basis for future in vivo and in vitro experiments aiming to improve effects of dose enhancement.

Evaluation of Image Quality for Compressed SENSE(CS) Method in Cerebrovascular MRI: Comparison with SENSE Method (뇌혈관자기공영영상에서 Compressed SENSE(CS) 기법에 대한 영상의 질 평가: SENSE 기법과 비교)

  • Goo, Eun-Hoe
    • Journal of the Korean Society of Radiology
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    • v.15 no.7
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    • pp.999-1005
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    • 2021
  • The object of this research is CS, which increases resolution while shortening inspection time, is applied to MRA to compare the quality of images for SENSE and CS techniques and to evaluate SNR and CNR to find out the optimal techniques and to provide them as clinical basic data based on this information. Data were analyzed on 32 patients who performed TOF MRA tests at a university hospital in Chung cheong-do (15 males, 17 females), ICA stenosis:10, M1 Aneurysm:10, and average age 53 ± 4.15). In the inspection, the inspection equipment was Ingenia CX 3.0T, Archieva 3.0T, and 32 channel head coil and 3D gradient echo as a method for equipment data. SNR and CNR of each image were measured by quantitative analysis, and the quality of the image was evaluated by dividing the observer's observation into 5 grades for qualitative evaluation. Imaging evaluation is described as being significant when the p-value is 0.05 or less when the paired T-test and Wilcoxon test are performed. Quantitative analysis of SNR and CNR in TOF MRA images Compared to the SENSE method, the CS method is a method measurement method (p <0.05). As an observer's evaluation, the sharpness of blood vessels: CS (4.45 ± 0.41), overall image quality: CS (4.77 ± 0.18), background suppression of images: CS (4.57 ± 0.18) all resulted in high CS technique (p = 0.000). In conclusion, the Compressed SENSE TOF MRA technique shows superior results when comparing and evaluating the SENSE and Compressed SENSE techniques in increased flow rate magnetic resonance angiography. The results are thought to be the clinical basis material in the 3D TOF MRA examination for brain disease.

Measurement of CT Numbers for Effective Atomic Number And Physical Density of Compound (화합물의 물리적 밀도와 유효원자번호에 대한 CT수 측정)

  • Kim, Jong Eon
    • Journal of the Korean Society of Radiology
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    • v.15 no.2
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    • pp.125-130
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    • 2021
  • In the AAPM CT performance phantom, there is little data on the CT number of the effective atomic number and physical density corresponding to each peg and water of the CT number calibration insert. Therefore, the necessity of documentation was raised.The purpose of this study is to calculate the effective atomic number for each peg and water of the CT number calibration insert in the AAPM CT performance phantom, and to measure the CT number for the calculated effective atomic number and physical density for comparative analysis.In order to obtain CT number data on the effective atomic number and physical density of each peg and water from the CT number calibration insert of the AAPM CT performance phantom, the effective atomic number for each peg and water was first calculated. Then, CT slices were obtained by scanning the CT number calibration with a CT scanner. CT numbers were measured for each peg and water in the central CT slice. As a result, the CT numbers for the effective atomic number showed a nonlinear pattern of repeating the increase and decrease as the effective atomic number increased. In addition, the CT numbers for physical density showed a nonlinear pattern of repeating the increase and decrease as the physical density increased.

Comparison of Linac-based VMAT Stereotatic Radiosurgery and Conventional Stereotatic Radiosurgery for Multiple Brain Lesions (Linac 기반 VMAT 정위적 수술 뇌 병변 연구와 기존의 정위적 방사선 수술 비교)

  • Jang, Eun-Sung;Chang, Bo-Seok
    • Journal of the Korean Society of Radiology
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    • v.15 no.2
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    • pp.239-246
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    • 2021
  • Portal Dosimetry was verified using EPID to secure the clinical application and reliability of the existing research dose evaluation. The dose distribution of Geant4 was compared with the measured value by 360° rotational irradiation with a 2.5 cm cone for stereotactic brain surgery. To confirm the dose distribution of patients with brain metastasis, the dose distribution investigated by inserting a Gafchromic EBT film into the parietal phantom and the dose distribution obtained from the parietal phantom using VMAT are compared and applied to actual patients. As a result of the analysis, it was confirmed that the accuracy of the beam center and the center of the couch coincide accurately with an error within 1mm as a result of QA through a pin ball. In addition, it was confirmed that the EBT3 film has excellent linearity in the range of 0 to 10 Gy according to various dose irradiation. In the same setting as the two cervical phantoms, we confirm that the implementation and simulation results calculations of dose calculations based on Geant4 using photon beams match the experimental data within the treatment planning volume (PTV). Therefore, volume modulated arc treatment (VMAT) 360° rotational irradiation was performed, and the result of iso-dose distribution analysis by rotational irradiation confirmed that it is appropriate to include a virtual tumor.

A Study on the Condition Analysis and Improvement of Domestic Medical 99Mo/99mTc Generators Self-disposal (국내 의료용 99Mo/99mTc Generator 자체 처분 지침 현황 분석 및 개선 방향에 대한 연구)

  • Ryu, Chan-Ju;Hong, Seong-Jong
    • Journal of the Korean Society of Radiology
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    • v.13 no.2
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    • pp.297-303
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    • 2019
  • The nuclear medicine department of a domestic medical institution uses $^{99m}TcI$, a radionuclide, from $^{99}Mo/^{99m}TcI$ Generator, to inject radioactive drugs into patients. Among the expired generators, imported from foreign countries, the medical institution implements its own disposal. Each medical institution shall satisfy the permitted in-house disposal concentration of radioactive wastes. The guidelines for self-disposal presented in Korea suggested that self-disposal can be performed 80 days after the generator is used. The purpose of these guidelines is to analyze them by comparing them with the data measured directly with the generator and to study if they are feasible. As a result, the generator with a capacity of 1,000 mCi has the longest half-life, and when tested with a high-radiation Mo(molybdenum) column, the number of days that are below the permitted concentration of body disposal with radioactive waste was 72 days and 71 days that were derived from direct column measurement. The results of the direct study confirmed that the guidelines for in-house disposal in Korea were reasonable, as there were 8 to 9 days of storage compared to the number of in-house disposal days provided in the guidelines.

Analysis of the Dead Layer Thickness effect and HPGe Detector by Penelope Simulation (Penelope Simulation에 의한 불감층 두께 효과 및 HPGe 검출기 분석)

  • Jang, Eun-Sung;Lee, Hyo-Yeong
    • Journal of the Korean Society of Radiology
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    • v.12 no.7
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    • pp.801-806
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    • 2018
  • Germanium crystals have a dead layer that causes efficiency deterioration because the layer is not useful for detection but strongly weakens the photons. Thus, when the data provided by the manufacturer is used in the detector simulation model, there is a slight difference between the calculated efficiency and the measured efficiency.The shape and dimensions of the high purity germanium (HPGe) detector were determined by CT scans to accurately characterize the shape for the Monte Carlo roll simulation. It is found that the adjustment of the dead layer is a good match with the relative deviation of ${\pm}3%$ between the measurement efficiency and the simulation efficiency at the energy range of 50 - 1500 keV. Simulation data were compared by varying the thickness of the dead layer. The new Monte Carlo simulations were compared with the experimental results to obtain new blank layer thicknesses. The difference in dead layer results for the 1.5 mm thick end cap simulation model in 1.4 and 1.6 mm thick End Cap simulation models was a systematic error due to the accuracy of the end cap dimensions. After considering all errors including statistical errors and systematic errors, the thickness of the detector was calculated as $1.02{\pm}0.14mm$. Therefore, it was confirmed that the increase in the thickness of the dead layer causes the effect to be effected on the efficiency reduction.