• 한방재활의학과학회지
• /
• 제30권4호
• /
• pp.187-194
• /
• 2020

The objective of this study is to report an accidental detection of colorectal cancer (CRC) metastasis to spine during conservative treatment for lumbar disc herniation. We treated a 65-year-old female who was diagnosed with lumbar disc herniation on September 2019 by acupuncture, pharmacopuncture, cupping treatment, chuna manual therapy, herbal medicine treatment, medicine treatment and physical therapy. After that we analyzed medical record from December 12, 2019 to February 11, 2020. The patient was diagnosed with CRC and received tumor resection in 2014. After 2 times of chemotherapy, she arbitrarily interrupted the treatment. Since she stated that CRC treatment was terminated, we had difficulty in finding connection between symptom and CRC. During the treatment period, compression fracture at L3 body was found, which was caused by CRC metastasis. Rigorous question, appropriate radiological and clinical tests are required to patients who have history of malignant tumor.

• 척추신경추나의학회지
• /
• 제4권1호
• /
• pp.95-102
• /
• 2009

Objectives : We studied in order to compare the differences between the symptoms of patients and findings of MRI and X-Ray of patients with herniated disc which has been diagnosed often recently. Methods : We randomly selected among the 301 patients with X-Ray and L-spine MRI films who have visited Jaseng Hospital with low-back pain and lumbar and low extremity pain from Jan.1st of 2009 to Jan.28. We used SPSS 13.0 for Windows I in analyzing statistical data of study results and the level of significance were below 0.05. Results and Conclusions : 1. If there were radiating pain, based on MRI findings, the amount of herniation was more severe(P>0.05). 2. If the finding of a X-ray showed narrowing, based on MRI findings, the amount of herniation was more severe(P>0.05). 3. There were no significant differences between the presence of radiating pain and the findings of X-Ray(P>0.05). 4. Among the 301 cases, cases which showed findings beside HIVD were 79. 7 cases of hemanggioma(2.3%), 24 cases of spinal neoplasm(cord cyst, tumor etc)(8%), 7 cases of spondylitis(2.3%), 16 cases of spinal canal stenosis(5,3%) 9 cases of ligamentum flavum thickening(3%) and 16 cases of facet syndrome(5.3%).

• 대한물리치료과학회지
• /
• 제9권4호
• /
• pp.7-14
• /
• 2002

The drug therapy for rheumatoid arthritis must be maintained constantly or for the whole life but is apt to induce the adverse effects in gastrointestinal or renal system. Therefor, newer methods are paid attention to reduce adverse effects. The thirty-two rat female separated into seven groups depending on the therapy or Freund's adjuvant applied: Normal group(n=8) not received anything, Positive control group(n=8) only received adjuvant, USC group(n=8) received continuous US, USP group(n=8) received pulsed US. The physical and radiological findings by thermal and non-thermal effects of ultrasound were evaluated in groups with continuous mode at 1 MHz, $0.5\;W/cm^2$ for 6 minutes and with pulsed mode (duty cycle 1:9) at 1 MHz, $0.5\;W/cm^2$ for 6 minutes. The result summarized followings. 1. Swelling of forepaw and hindpaw was significantly reduced in USP. 2. Arthritis indices in USP group were significantly reduced than those in PCG. 3. In naked eye and radiologic findings, swelling was significantly prevented in USP group but not in PCG. The change of swelling, arthritis index, gross feature in naked eye, radiologic finding were significantly improved in all groups except for USC group, taking care for using its continuous mode.

• 한국수정란이식학회지
• /
• 제32권3호
• /
• pp.183-192
• /
• 2017

The mammary gland tumor (MGT) is the most common neoplasia in intact female dogs. Of these, 50% are malignant and metastasis to the other sites are often occurred. Therefore, it is very important for decision of treatment plan and prognosis to differentiate benign tumor from malignancies. Calcification of MGT is a very important imaging finding. The purpose of this study was to investigate the radiological and computed tomographic images of the MGT and the morphology and distribution of calcifications in the MGT using the Breast Imaging Reporting and Data System classification. A total of 42 dogs with MGT were included in this study. The dogs were divided into two groups into benign and malignant groups based upon histologic or cytologic results. The appearance of calcification in the tumor on radiographs and CT images was analyzed for the HU value of pre- and post-contrast injection, margin, surface, and shape of the tumor and the lymph node abnormalities. On radiographs, the positive predictive value of malignant and benign tumors was 72.72 and 85.71%, respectively. On CT examinations, the positive predictive value of malignant and benign tumors was the same value of 83.33%. The maximum diameter of the tumor and the presence of abnormal lymph nodes on CT images showed a strong correlation with malignancies. Therefore, it is thought that radiographs and CT provide useful information for evaluating MGT in dogs.

• 한국방사선학회논문지
• /
• 제13권4호
• /
• pp.509-516
• /
• 2019

전산화단층촬영에서 선형 및 비선형변환방법을 이용하여 탐색밀도에 따른 압축률과 최대신호대 잡음비를 구하여 의료영상 압축의 화질에 대하여 알고자 한다. 선형변환방법은 원 영상을 여러 개의 레인지블록으로 나눈 후 각각의 레인지블록에 대하여 영상내의 존재하는 최적의 도메인블록을 찾는 부분변환시스템을 사용하여 닮은 블록을 찾아서 압축율과 화질의 성능을 조정가능 하므로 비선형변환방법은 8개의 셔플변환 중에서 회전변환만을 이용하는데, 한정된 도메인블록에서만 탐색이 이루어지므로 영상내의 임의의 블록에 대하여 도메인블록을 탐색하는 선형변환방법보다는 부호화 시간이 빠르나 실제 영상에서 레인지블록에 대한 최적의 도메인블록을 선택할 수 없기 때문에 성능은 다른 방법에서 보다 떨어질 수 있어서 비선형변환방법은 최적의 도메인블록을 선택하는 대신 밝기계수 변환의 근사화 정도를 높여서 성능을 개선하고, 블록의 크기가 작을수록 최대신호대 잡음비(PSNR;peak signal to noise ratio)값은 높아지며 블록의 크기가 클수록 압축비가 높아지므로 최적으로 영상을 부호화하기 위해 퀴드트리 블록분할을 하였다.

• 대한영상의학회지
• /
• 제81권4호
• /
• pp.979-984
• /
• 2020

묘성증후군은 드문 유전자 결손 증후군으로, 환아는 후두 및 후두개의 기형과 신경학적 구조적 이상으로 인해 특징적인 높은 톤의 단조로운 울음소리를 내고 반복적인 흡인성 폐렴을 앓는다. 이전 보고된 증례들의 뇌 자기공명영상 소견을 정리한 결과 교뇌 저형성이 가장 뚜렷하였고, 소뇌 저형성이 동반되기도 하여 주로 후두개와의 이상 소견을 보였다. 천막상부 구조물의 위축도 자주 관찰되었는데 이것은 교뇌 저형성에 의한 이차적인 변화로 생각되었다. 본원에서 확진된 3개월 환아 또한 교뇌 저형성이 두드러져 이전 보고된 증례들과 거의 유사하였으나 수초화 양상에서 내섬유막 전완의 수초화 감소가 아니라 전반적인 수초화의 지연이 관찰되었다는 점에서 타 증례와 차이가 있었다. 후두, 교뇌, 소뇌는 비슷한 척삭에서 유래하므로, 묘성증후군에서 생기는 후두 및 뇌의 구조적 이상은 발생 초기의 이상임을 시사한다.

• Korean Journal of Radiology
• /
• 제20권6호
• /
• pp.967-975
• /
• 2019

Objective: To evaluate whether the combination of magnetic resonance spectroscopy (MRS) and ¹¹C-methionine positron emission tomography (¹¹C-MET PET) could increase accurate diagnostic sensitivity for non-enhancing supratentorial gliomas. Materials and Methods: Between February 2012 and December 2017, 109 patients with non-enhanced supratentorial lesions on contrast-enhanced MRI were enrolled. Each patient underwent MRS and ¹¹C-MET PET before treatment. A lesion was considered to be a glioma when either the MRS or ¹¹C-MET PET results reached the diagnostic threshold. The radiological diagnosis was compared with the pathological diagnosis or medical diagnostic criteria. Results: The sensitivity and specificity were 60.0% and 50.0% for MRS and 75.8% and 50.0% for ¹¹C-MET PET, respectively. Upon combining the two modalities, the sensitivity and specificity of the imaging-based diagnosis prior to surgery reached 89.5% and 42.9%, respectively. Statistically significant differences in the sensitivities were observed between the combined and individual approaches (MRS alone, 89.5% vs. 60.0%, p < 0.001; ¹¹C-MET PET alone, 89.5% vs. 75.8%, p = 0.001). However, no significant differences in specificity were observed between the combined and individual modalities. Conclusion: The combination of MRS and ¹¹C-MET PET findings significantly increases accurate diagnostic sensitivity for non-enhancing supratentorial gliomas without significantly lowering the specificity. This finding suggests the potential of the combined MRS and ¹¹C-MET PET approach in clinical applications.

• 방사선산업학회지
• /
• 제17권4호
• /
• pp.385-390
• /
• 2023

The uterus, one of women's reproductive organs, is also closely related to women's health. Among them, hemorrhagic luteal cysts, one of the causes of pelvic pain that women often experience, were observed through CT and ultrasound, and the quality of images was evaluated through quantitative and qualitative evaluations. This study sought to find out whether the test method is more helpful to patients during CT and ultrasound. This study was conducted on 15 adolescent women and 15 adult women(21.31±3.45 average age). The equipment used for filming used EC3-10X (3~10 MHZ) and Philips Mx8000 iCT 256 among Endocavity Probes among Ecube Platinum. After setting a constant ROI on the cyst and the interface as a quantitative analysis method, SNR and CNR values were measured on a 5-point scale based on image quality, lesion clarity, image distortion, clarity of the interface, and motion artifacts (p<0.05). Independent t-test and Mann Whiteny U were performed, and the statistical program used was noted when SPSS (Version 22.0 for windows software package, Chicago, IL, USA) was statistically less than 0.05. Comparing the SNR and CNR values for this experiment, it can be seen that the SNR value was higher in the case of CT images(p<0.05). As a result of the qualitative evaluation, the quality of the image, the clarity of the lesion, the distortion of the image, the clarity of the interface, and the clarity of the boundary were measured on a 5-point scale based on the movement artifact. Comparing each score, CT images scored higher with a finer difference than ultrasound images(p<0.05). In conclusion, both test methods showed excellent results in finding the patient's lesions. However, in quantitative and qualitative evaluations, CT produced higher results in detecting lesions than ultrasound. However, for cyst tests that require continuous observation, ultrasonography, a non-invasive method that is advantageous for patients, will be clinically useful. Therefore, observing the patient's lesions by appropriately distributing these two test methods will provide optimal diagnostic information. These results will be useful for providing clinical basic data and educational materials to CT and US users in the future.

• Nuclear Engineering and Technology
• /
• 제56권6호
• /
• pp.2050-2056
• /
• 2024

Handling of radioisotopes may cause external and internal contamination to occupational workers while using radiation for medical purposes. This research aims to monitor the internal hazard of occupational workers who handle ¹³¹I. Two methods are used: in vivo or direct method and in vitro or indirect method. The in vivo or direct method was performed by assessing thyroid intake with a thyroid uptake monitoring machine. The in vitro or indirect method was performed by assessing urine samples with the help of a gamma-ray spectroscopy practice using a High-Purity Germanium (HPGe) Detector. In this study, fifty-nine thyroid counts and fifty-nine urine samples were collected from seven occupational workers who were in charge of ¹³¹I at the National Institute of Nuclear Medicine and Allied Sciences (NINMAS), Dhaka. The result showed that the average annual effective dose of seven workforces from thyroid counts were 0.0208 mSv/y, 0.0180 mSv/y, 0.0135 mSv/y, 0.0169 m Sv/y, 0.0072 mSv/y, 0.0181 mSv/y, 0.0164 mSv/y and in urine samples 0.0832 mSv/y, 0.0770 mSv/y, 0.0732 mSv/y, 0.0693 mSv/y, 0.0715 mSv/y, 0.0662 mSv/y, 0.0708 mSv/y.The total annual effective dose (in vivo and in vitro method) was found among seven workers in average 0.1039 mSv/y, 0.0950 mSv/y, 0.0868 mSv/y, 0.0862 mSv/y, 0.0787 mSv/y, 0.0843 mSv/y, 0.0872 mSv/y. Following the rules of the International Commission on Radiological Protection (ICRP), the annual limit of effective dose for occupational exposure is 20 mSv per year and the finding values from this research work are lesser than this safety boundary.

• 한국의학물리학회지:의학물리
• /
• 제20권4호
• /
• pp.235-243
• /
• 2009

다양한 간 질환에 Ferucarbotran (SPIO)과 Gd-EOB-DTPA (Primovist) 조영제를 사용하여 자기공명영상 상에서 비교하여 간 질환의 특성 및 검출 과 그 질환에 따른 조영제 흡수관계를 알아보고자 한다. 실험대상은 국소 간 병변을 가진 50명의 환자 중 남자 25명, 여자 25명으로 평균나이는 50세이었다. 사용된 장비와 코일은 3.0T (General Electric Medical System, Excite HD) 자기공명영상장치와 8채널 채부코일이었다. 질환과 조영제 흡수관계를 비교하기 위하여 사용된 펄스 시퀀스는 Liver aquisition with volume acceleration (LAVA)와 Multi-Gradient rapid Echo (MGRE)이었다. 모든 검사기법은 일정한 데이터를 획득하기 위하여 Ferucarbotran (SPIO) 및 Gd-EOB-DTPA (Primovist) 조영제를 주입 전 후에 같은 위치를 선정하여 검사를 시행했다(p<0.05). 검사 결과는 Ferucarbotran와 Gd-EOB-DTPA의 대조도대 잡음비는 간세포암(HCC, 16 cases)이 $3.08{\pm}0.12$과 $7.00{\pm}0.27$이었다. 과다형성결절(Hyperplastic Nodule, 7 cases) 질환은 $3.62{\pm}0.13$, $2.60{\pm}0.23$, 전이(Metastasis, 13 cases)는 $1.70{\pm}0.09$, $2.60{\pm}0.23$, 초점성 결절성 과증식(Focal Nodular Hyperplasia, 6 cases)질환은 $2.12{\pm}0.28$, $5.86{\pm}0.28$, 농양(Abscess, 8 cases)은 $4.45{\pm}0.28$, $1.73{\pm}0.02$이었다. 또한, 각 질환에 대한 진단적 수행을 위해 ANOVA 검증을 하였다(p<0.05). 결론적으로, 두 조영제 효과로 2개 검사기법 모두가 간질환의 특성 및 검출과 그 질환에 따른 조영제 특성을 잘 보여주었다.