• Title/Summary/Keyword: radiation response

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Follow-Up Consultations for Cervical Cancer Patients in a Mexican Cancer Center. Comparison with NCCN Guidelines

  • Serrano-Olvera, Alberto;Cetina, Lucely;Coronel, Jaime;Duenas-Gonzalez, Alfonso
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.8749-8752
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    • 2014
  • Purpose: This study aimed to determine the patterns of follow-up visits for cervix cancer in a national cancer center in Mexico. Materials and Methods: The National Cancer Institute of Mexico is cancer center with 119 beds that mostly cares for an underserved and socially disadvantaged population. The medical records of cases of cervical cancer that had at least one year of clinical follow-up after being in complete response at the end of primary treatment were analyzed. We recorded the numbers of total and yearly follow-up visits and these were compared with the number of follow-up visits recommended by the National Comprehensive Cancer Network 2013, version 2 for cervical cancer. Results: Between March and June 2007, the medical records of 96 consecutive patients were reviewed. Twenty (21%) of these met inclusion criteria and were selected. In the first year the median number of visits was 11 (4-20). In the ensuing years, $2^{nd}$, $3^{rd}$, $4^{th}$ and $5^{th}$, the number of analyzed patients remaining in follow-up decreased to 17, 14, 13 and 9 respectively. There were 462 follow-up visits to primary treating services (Gynecology Oncology, Radiation Oncology and Medical Oncology) as compared to 220 suggested by the NCCN guidelines ($X^2$ test p<0.0001). There were 150 additional visits to other services. Conclusions: Our results suggest that in our institution there is an overuse of oncological services by cervical cancer patients once treatment is completed.

Effect of Ethanol Extracts of Raw and Boiled Bracken on Blood Pressure in Cats (고사리 (Pteridium aquilinum) Ethanol 추출액(抽出液)에 의한 혈압강하작용(血壓降下作用))

  • Koh, Sang-Don;Kim, Kee-Soon
    • The Korean Journal of Physiology
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    • v.18 no.2
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    • pp.171-180
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    • 1984
  • The death of cattle from acute bracken poisoning has been recognized for many years. Acute bracken poisoning is characterized by mucoidal nasal and anal hemorrhage, severe anorexia. pyrexia, gastric ulcer and myocardial damage. In 1958 Evans first suggested that clinical picture of bracken poisoning was very much similar to that of radiation injuries such as aplastic anemia, leucopenia, thrombocytopenia and increased capillary fragility. Bracken has been clearly demonstrated to contain a carcinogen as well as thiaminase. However, the nature of carcinogen in bracken has not definetely elucidated. Also it was warned by several workers that bracken could be a causative factor for stomach cancer in Korean and Japanese. It appears that little is known on the e(feet of bracken on the function of cardiovascular system. Therefore the present study was designed to explore effects of ethanol extract of raw and toiled bracken (RBEE:BBEE) on blood pressure in cats. Also studied was the mechanism underlying changed in blood pressure of cats by bracken. The result obtained were as follows; 1) Mean arterial blood pressure was invariably decreased following administration of either RBEE or BBEE. Tn general depressor responses to RBEE persisted longer than that to BBEE. Generally, depressor responses were proportional to debases of RBEE and BBEE administered. 2) After administration of 60 mg/kg RBEB and BBEE, blood Pressure decreased by $62.1{\pm}1.7mmHg$ and $68.0{\pm}3.0mmHg$, respectively. No change was observed between depressor responses to RBEE and that to BBEE. 3) Depressor responses to BBEE and RBEE were not affected by vagotomy, propranolol and regitine. 4) In atropinized animal depressor responses to BBEE and RBEE were reduced by 30-40% showing part of depressor response was resulted from cholinergic effect of bracken.

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A Study on the Proper Chest Exposure Conditions of Mobile Digital X-ray Unit by Exposure Index (Exposure Index를 이용한 이동형 디지털 X선 장치의 흉부촬영 적정노출조건에 관한 연구)

  • Kim, Jae-In;Lee, Yang-Sub;Jang, Dong-Soo;Jung, Min-Cheol;Bae, Seung-Ho;Lee, Kwan-Sub;Ha, Dong-Yoon
    • Korean Journal of Digital Imaging in Medicine
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    • v.13 no.3
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    • pp.139-144
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    • 2011
  • The purpose of this report is recommending a standard indicator which reflects the radiation exposure that is incident on a detector after every exposure event and that reflects the noise levels present in the image data. The experiment was performed with mobile digital X-ray unit and used a acrylic phantom for exposure index measurement. Exposure modality was kVp, mAs, SID. After every exposure, make a data sheet for characteristic curve of detector response. The equipment performed Mobile digital X-ray unit provide the user with values ralated to the incident exposure(air kerma)to the digital detector. They are showed as a logarithmic function shaped. As a result, DEI means a relative measure of exposure to the detector, as compared to the expected exposure for a particular anatomical view. Radiographic technique is the combination of factors used to exposure an anatomical part to produce a high quality radiography and technique charts used most commonly by radiographers to produce consistently exposure level which patient dose can be kept acceptably low.

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Implementation of Digital Mammogram CAD Algorithm (디지털 유방영상의 CAD 알고리즘 구현)

  • Lee, Byungchea;Choi, Guirack;Jung, Jaeeun;Lee, Sangbock
    • Journal of the Korean Society of Radiology
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    • v.8 no.1
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    • pp.27-33
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    • 2014
  • Medical imaging has increased rapidly in the increase of interest in health, with the development of computer technology, digitization of medical imaging is rapidly advancing, PACS has been introduced to the medical field. Increase in the production of medical images by these phenomena made increased the workload of radiologist who must read a medical image. in response to the need for secondary diagnosis using a computer, The term of CAD in medical radiology field was introduced. In this study, we have proposed a CAD algorithm for the interpretation of the image obtained by the digital X-ray mammography equipment. The experiments were performed by programmed in Visual C++ for the proposed algorithm. A result of the execution of the CAD algorithm seven sample images, the results of five samples was confirmed in breast cancer and benign tumors, both the images sample was error processing. If you use a program that implements this with the algorithm proposed in this study it is helpful to reading breast images, and it is considered to contribute significantly to the early detection of breast cancer.

Chronic Wound Treatment Using rh PDGF (재조합 인체 혈소판 성장인자(rh PDGF)를 이용한 만성 창상의 치료)

  • Jeong, Wong-Ki;Lew, Dae-Hyun;Park, Beyoung-Yun
    • Archives of Reconstructive Microsurgery
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    • v.11 no.2
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    • pp.173-178
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    • 2002
  • Wound healing is the result of interaction of normal cellular and biochemical responses that restore the interrupted anatomical structure in limited period. When any response of them is impaired, it results in chronic wound. The factors that influence the wound healing process is not only limited to the fundamental disease of the individual but also the local factors, especially various growth factors secreted from the various cells involved in tissue regeneration have important role. Recent reports that the chronic wounds are depleted of these growth factors have led active studies on the alteration of local wound environment with manipulation of the growth factors and the its application in management of chronic wounds. We investigated the effect on the chronic wounds in 10 patients with various pathologic conditions to suggest the appropriate application and guideline of the indication. The chronic wounds resulting from various causes in 10 patients were treated with rhPDGF gel and good wound care. All the chronic wounds were located on the lower extremity and the average diameter was 2.5 cm. 7 patients were completely cured within 8 weeks, however the patient who received previous radiation therapy the healing was delayed to 14 weeks. Two patients with vascular ulcer were not cured with rhPDGF alone. Local application of rhPDGF has yielded complete cure of the chronic wound in 70% of the patients within 2 months. The author suggests that it would be an effective alternative treatment modality of chronic wound when it is applied with good wound care and appropriate indication.

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Structural Design of Digital Radiography Detector using Hybrid Method for the Improvement of Response Property by X-ray (X-ray 반응 특성 개선을 위한 Hybrid형 디지털 방사선 검출기의 구조 설계)

  • Kim, Kyo-Tae;Han, Moo-Jae;Kim, Jin-Seon;Heo, Ye-Ji;Oh, Kyung-Min;Park, Ji-Koon;Nam, Sang-Hee
    • Journal of the Korean Society of Radiology
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    • v.9 no.6
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    • pp.363-367
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    • 2015
  • Digital radiography is divided into the direct method using photoconductor and indirect method using phosphor based on the principles in acquiring the image information, but both have different advantages and disadvantages. Therefore, this study conducted a preliminary research on the structure of the hybrid detector that combined phosphor and photoconductor to improve the sensitivity of X-ray. As a result, when the tube voltage was adjusted at 30ms of exposure time, the direct structure displayed an overall excellent sensitivity, but at the exposure time of 50ms or more, the hybrid structure displayed a better outcome. This seems to have enough research value considering that various clinical examinations usually include 50ms or more exposure time.

Effect of Nitrogen Fertilization on Growth, Forage Yield and Nitrogen Use of Sudangrass (질소시비에 대한 Sudangrass의 생육 및 수량반응과 질소이용성)

  • 윤진일;이호진
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.27 no.1
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    • pp.66-71
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    • 1982
  • Field experiments of nitrogen application (0, 100, 200, 400, 800kg N/ha year) were carried out to study the nitrogen response of Sudangrass at College Farm, Seoul National Univ., in 1979 and 1980. Dry matter yield and leaf area index increased up to 400kg N/ha in 1979 and 800kg N/ha in 1980. The forage yield of 1980 was less than that of 1979, due to the extraordinarily low temperature and the decreased solar radiation during summer. Total nitrogen contents in forage increased with nitrogen application, but maximum contents were found either 400 or 800kg N levels depend on each cutting stages. Nitrate nitrogen content in forage exceded over 2000 ppm at 800kg N application. Overall percentages of N recovery were below 50% with average 34%. Net assimilation rate and nitrogen use efficiency of Sudangrass were improved in higher temperature and more sunlight condition during regrowth period.

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Clinical Analysis of Novalis Stereotactic Radiosurgery for Brain Metastases

  • Gu, Hae-Won;Sohn, Moon-Jun;Lee, Dong-Joon;Lee, Hye-Ran;Lee, Chae-Heuck;Whang, C.-Jin
    • Journal of Korean Neurosurgical Society
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    • v.46 no.3
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    • pp.245-251
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    • 2009
  • Objective : The authors analyzed the effectiveness and therapeutic response of Novalis shaped beam radiosurgery for metastatic brain tumors, and the prognostic factors which influenced the outcome. Methods : We performed a retrospective analysis of 106 patients who underwent 159 treatments for 640 metastatic brain lesions between January 2000 and April 2008. The pathologies of the primary tumor were mainly lung (45.3%), breast (18.2%) and GI tract (13.2%). We classified the patients using Radiation Therapy Oncology Group Recursive Partitioning Analysis (RPA) and then analyzed the survival and prognostic factors according to the Kaplan Meier method and univariate analysis. Results : The overall median actuarial survival rate was 7.3 months from the time of first radiosurgery treatment while 1 and 2 year actuarial survival estimates were 31% and 14.4%, respectively. Median actuarial survival rates for RPA classes I, II, and III were 31.3 months, 7.5 months and 1.7 months, respectively. Patients' life spans, higher Karnofsky performance scores and age correlated closely with RPA classes. However, sex and the number of lesions were not found to be significantly associated with length of survival. Conclusion : This result suggests that Novalis radiosurgery can be a good treatment option for treatment of the patients with brain metastases.

Laterally Loaded Soil-Pile Interaction Analysis in Frequency Domain (횡하중을 받는 지반-말뚝 상호작용계의 동적 주파수 응답해석)

  • 김문겸;임윤묵;김민규;조석호
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.13 no.4
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    • pp.437-448
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    • 2000
  • In this study, a numerical analysis method for soil-pile interaction in frequency domain problem is presented. The total soil-pile interaction system is divided into two parts so called near field and far field. In the near field, beam elements are used lot a pile and plain strain finite elements for soil. In the far field, dynamic fundamental solution for multi-layered half planes based on boundary element formulation is adopted lot soil. These two fields are coupled using FE-BE coupling technique. In order to verify the proposed soil-pile interaction analysis, the dynamic responses of pile on multi-layered half planes are simulated and the results are compared with the experimental results. Also, various numerical analyses of piles considering different conditions of soil-pile interaction system are performed to examine the dynamic behavior of the system. It has been found that the developed method which satisfies the radiation conditions of multi-layered half planes can be applied to various structure systems effectively in frequency domain.

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Dynamic Boundary Element Analysis of Underground Structures Using Multi-Layered Half-Plane Fundamental Solutions (2차원 다층 반무한해를 이용한 지하구조계의 동적 경계요소 해석)

  • 김문겸;이종우;조성용
    • Journal of the Earthquake Engineering Society of Korea
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    • v.1 no.4
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    • pp.59-68
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    • 1997
  • In analysis of underground structures, the effects of artificial boundary conditions are considered as one of the major reasons for differences from experimental results. These phenomena can be overcome by using the boundary elements which satisfy the multi-layered half space conditions. The fundamental solutions of multi-layered half-space for boundary element method is formulated satisfying the transmission and reflection of waves at each layer interface and radiation conditions at bottom layer. The governing equations can be obtained from the displacements at each layer which are expressed in terms of harmonic functions. All types of waves can be included using the complete response from semi-infinite integrals with respect to horizontal wavenumbers using expansion of Fourier series and Hankel transformation. Two dimensional Green's functions are derived from cylindrical Navier equations and potentials performing infinite integration in y-direction. In this case, it is effective to transform into two dimensional problem using semi-analytical integration and sinusoidal Bessel function. Some verifications are given to show the accuracy and efficiency of the developed method, and numerical examples to demonstrate the dynamic behavior of underground with various properties.

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