• 한국엔터테인먼트산업학회논문지
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• 제14권7호
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• pp.571-579
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• 2020

응급구조(학)과 학생들의 방사선 방어에 관한 지식, 태도 및 교육요구도를 조사하고 분석하여 방사선 방어를 위한 안전관리의 교육과정 프로그램 개발에 기초자료를 제공하기 위해 시행되었다. 연구대상자 244명을 분석한 결과 방사선 방어에 대한 지식 점수는 9.50점, 방사선 방어 태도 점수는 30.24점이었다. 방사선 방어에 대한 지식과 태도 모두 방사선 방어 교육을 받은 군이 받지 않은 군에 비해 통계학적으로 유의하게 높았고, 지식과 태도 간의 상관관계에서는 방사선 방어에 대한 태도 점수와 지식 점수와는 양의 상관관계를 보여(r=.472, p<.000), 응급구조(학)과 학생들의 지식 점수가 높아질수록 태도 점수가 높아진다는 것을 알 수 있었다. 방사선 방어 교육을 받은 대상자는 6.1%, 교육요구는 87.3%, 참여 의향은 82.0%, 교육시기는 2학년이 54.9%로 가장 높았다. 교육방법은 시청각 교재를 활용한 강의가 59.04%로 가장높았고, 강연자는 방사선사가 77.45%로 가장 높았다. 이 결과로부터 응급구조(학)과 학생들의 방사선 방어에 대한 지식 점수와 태도 점수가 낮음에도 불구하고 교육요구와 참여 의도가 높음을 알 수 있었고 교육효과를 높이기 위해서는 방사선사가 시청각 교재를 활용하여 교육을 실시하는 것이 가장 효과적이라는 결론을 얻었다.

• Journal of Radiation Protection and Research
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• 제12권2호
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• pp.51-54
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• 1987

• Journal of Radiation Protection and Research
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• 제15권1호
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• pp.15-17
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• 1990

• Journal of Radiation Protection and Research
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• 제15권1호
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• pp.1-8
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• 1990

• Journal of Radiation Protection and Research
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• 제19권1호
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• pp.81-93
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• 1994

• Molecules and Cells
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• 제25권2호
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• pp.224-230
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• 2008

Ceramides are well-known second messengers that induce apoptosis in various kinds of cancer cells, and their effects are closely related to radiation sensitivity. Phytoceramides, the yeast counterparts of the mammalian ceramides, are also reported to induce apoptosis. We investigated the effect of a novel ceramide derivative, N-acetylphytosphingosine (NAPS), on the radiosensitivity of NCI-H460 human lung carcinoma cells and its differential cytotoxicity in tumor and normal cells. The combination of NAPS with radiation significantly increased clonogenic cell death and caspase-dependent apoptosis. The combined treatment greatly increased Bax expression and Bid cleavage, but not Bcl-2 expression. However, there was no effect on radiosensitivity and apoptosis in BEAS2B cells, which derive from normal human bronchial epithelium. Cell proliferation and DNA synthesis were significantly inhibited by NAPS in both NCI-H460 and BEAS2B cells, but only the BEAS2B cells recovered by 48h after removal of the NAPS. Furthermore, the NCI-H460 cells underwent more DNA fragmentation than the BEAS2B cells in response to NAPS. Our results indicate that NAPS may be a potential radiosensitizing agent with differential effects on tumor vs. normal cells.

• International Journal of Oral Biology
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• 제46권4호
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• pp.168-175
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• 2021

To investigate the perceptions and attitudes of dental hygienists toward radiation safety management in Korea. A total of 800 dental hygienists were randomly selected for an anonymous survey, and 203 of them participated. The questionnaire items included the following: sex, career period, type of installed radiographic equipment, recognition of the diagnostic reference level (DRL), participation in radiation safety education, and attitudes toward radiation protection for both patients and dental hygienists. The participants were divided into two groups according to their years of experience (< 10 years versus ≥ 10 years). The difference between the groups was investigated according to frequency distribution. Fisher's exact test or Pearson's chi-square (𝛘²) test was used as appropriate. A regression analysis was performed to investigate the impact of wearing a thyroid collar for personnel protection during patient radiation exposure. The types of installed radiographic equipment included panoramic radiography (96.1%), cephalometric radiography (76.9%), intraoral radiography (72.9%), and cone-beam computed tomography (69.5%). Significant differences were observed in the learning pathway for the DRL (Fisher's exact test, p < 0.05), satisfaction with radiation safety education (Pearson's 𝛘² test = 5.3975, Pr = 0.02), and use of personnel radiation monitoring systems (Pearson's 𝛘² test = 18.1233, Pr = 0.000) between the groups. Significant differences were also observed in personnel protection using a thyroid collar and patient protection during panoramic radiography (odds ratio = 14.2). Dental hygienists with more than 10 years of experience were more satisfied with radiation safety education and more interested in radiation monitoring. Considering career experience, customized, continuous, and effective radiation safety management education should be provided.

• Journal of Microbiology and Biotechnology
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• 제28권4호
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• pp.527-533
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• 2018

This study compared the radioprotective effects of high-molecular-weight poly-gamma-glutamate (${\gamma}-PGA$, average molecular mass 3,000 kDa) and a reduced form of glutathione (GSH, a known radioprotector) on calf thymus DNA damage. The radiation-induced DNA damage was measured on the basis of the decreased fluorescence intensity after binding the DNA with ethidium bromide. All the experiments used $^{60}Co$ gamma radiation at 1,252 Gy, representing 50% DNA damage. When increasing the concentration of ${\gamma}-PGA$ from 0.33 to $1.65{\mu}M$, the DNA protection from radiation-induced damage also increased, with a maximum of 87% protection. Meanwhile, the maximal DNA protection when increasing the concentration of GSH was only 70%. Therefore, ${\gamma}-PGA$ exhibited significant radioprotective effects against gamma irradiation.

• Journal of Radiation Protection and Research
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• 제28권2호
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• pp.137-143
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• 2003

Annual radiation dose limit to radiation worker was substantially lowered in Korea by the adoption of 1990 recommendations of the International Commission on Radiation Protection (ICRP 60) in its legislation. On the other hand, radiation management environment in nuclear power plants is getting more worse because of the accumulation of radiation sources inside the system and the frequent need for maintenance according as the operation years of nuclear power plants increase. Therefore, Korea Hydro & Nuclear power Co., Ltd. (KHNP) has established a long-term 10 years plan from 2001 to 2010 for the reduction of radiation dose to workers. The plan is aimed for the reduction of annual dose per unit averaged over 5 years from 0.9 man-Sv in 2001 to 0.75 man-Sv in 2010 by radiation source reduction, equipment/tool improvement or new equipment development for easy maintenance, and the improvement of administration and system.

• Journal of Radiation Protection and Research
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• 제41권3호
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• pp.310-314
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• 2016

Background: FCTC10 container is designed to transport $^{60}Co$ radioactive sources used in irradiation industry. It belongs to Type B(U) Category III (yellow) package when being loaded with a $^{60}Co$ source of $1.8{\times}10^5$ Ci. Materials and Methods: The container is constituted of shielding container, basket, protective cover and bracket. Shielding ability is provided mainly by stainless steel shells, tungsten alloy and lead among steel shells. Radiation level around the container has been calculated with both Monte Carlo simulations and measurements. Results and Discussion: It is proven that the shielding performance of the container fulfills the requirements in GB11806-2004 (Regulations for the safe transport of radioactive material, China Standard Press). Exposure doses to workers and to critical groups of public were calculated based on hypothetical exposure scene according to transport practice experience. Conclusion: The results show that doses to workers and public are less than the constraint dose considered in design, and the radiation level would be increased less than a factor of 2 under design basis accidents.