• Title/Summary/Keyword: radiation dose

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DOSE AND DOSE RATE EFFECTS OF IRRADIATION ON BLOOD COUNT AND CYTOKINE LEVEL IN BALB/c MICE

  • Son, Yeonghoon;Jung, Dong Hyuk;Kim, Sung Dae;Lee, Chang Geun;Yang, Kwangmo;Kim, Joong Sun
    • Journal of Radiation Protection and Research
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    • 제38권4호
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    • pp.179-184
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    • 2013
  • The biological effects of radiation are dependent on the dose rate and dose of radiation. In this study, effects of dose and dose rate using whole body radiation on plasma cytokines and blood count from male BALB/c mice were evaluated. We examined the blood and cytokine changes in mice exposed to a low (3.49m Gy $h^{-1}$) and high (2.6 Gy $min^{-1}$) dose rate of radiation at a total dose of 0.5 and 2 Gy, respectively. Blood from mice exposed to radiation were evaluated using cytokine assays and complete blood count. Peripheral lymphocytes and neutrophils decreased in a dose dependent manner following high dose rate radiation. The peripheral lymphocytes population remained unchanged following low dose rate radiation; however, the neutrophils population increased after radiation. The sera from these mice exhibited elevated levels of flt3 ligand and granulocyte-colony-stimulating factor (G-CSF), after high/low dose rate radiation. These results suggest that low-dose-rate radiation does not induce blood damage, which was unlike high-dose-rate radiation treatment; low-dose-rate radiation exposure activated the hematopoiesis through the increase of flt3 ligand and G-CSF.

Radiation Exposure from Nuclear Power Plants in Korea: 2011-2015

  • Lim, Young Khi
    • Journal of Radiation Protection and Research
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    • 제42권4호
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    • pp.222-228
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    • 2017
  • Background: On June 18, 2017, Korea's first commercial nuclear reactor, the Kori Nuclear Power Plant No. 1, was permanently suspended, and the capacity of nuclear power generation facilities will be adjusted according to the governments denuclearization policy. In these circumstances, it is necessary to assess the quality of radiation safety management in nuclear power plants in Korea by evaluating the radiation dose associated with them. Materials and Methods: The average annual radiation dose per unit, the annual radiation dose per person, and the annual dose distribution were analyzed using the radiation dose database of nuclear reactors for the last 5 years. The results of our analysis were compared to the specifications of the Nuclear Safety Act and Medical Law in Korea. Results and Discussion: The annual average per unit radiation dose of global major nuclear power generation was 720 man-mSv, while that of Korea's nuclear power plants was 374 manmSv. No workers exceeded 50 mSv per year or 100 mSv in 5 years. The individual radiation dose according to occupational exposure was 0.59 mSv for nuclear workers, 1.77 mSv for non-destructive workers, and 0.8 mSv for diagnostic radiologists. Conclusion: The radiation safety management of nuclear power plants in Korea has achieved the best outcomes worldwide, which is considered to be the result of the as-low-as-reasonably-achievable (ALARA) approach and strict radiation safety management. Moreover, the occupational exposures were also very low.

저선량 방사선 노출과 건강 영향에 대한 역학적 고찰 (Epidemiology of Low-Dose Ionizing Radiation Exposure and Health Effects)

  • 이원진
    • 한국환경보건학회지
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    • 제49권1호
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    • pp.1-10
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    • 2023
  • Low-dose radiation exposure has received considerable attention because it reflects the general public's type and level of exposure. Still, controversy remains due to the relatively unclear results and uncertainty in risk estimation compared to high-dose radiation. However, recent epidemiological studies report direct evidence of health effects for various types of low-dose radiation exposure. In particular, international nuclear workers' studies, CT exposure studies, and children's cancer studies on natural radiation showed significantly increased cancer risk among the study populations despite their low-dose radiation exposure. These studies showed similar results even when the cumulative radiation dose was limited to an exposure group of less than 100 mGy, demonstrating that the observed excess risk was not affected by high exposure. A linear dose-response relationship between radiation exposure and cancer incidence has been observed, even at the low-dose interval. These recent epidemiological studies include relatively large populations, and findings are broadly consistent with previous studies on Japanese atomic bomb survivors. However, the health effects of low-dose radiation are assumed to be small compared to the risks that may arise from other lifestyle factors; therefore, the benefits of radiation use should be considered at the individual level through a balanced interpretation. Further low-dose radiation studies are essential to accurately determining the benefits and risks of radiation.

방사선피폭관리시스템를 위한 D-Shuttle 선량계의 방사선 선량측정 (Radiation Dose Measurement of D-Shuttle Dosimeter for Radiation Exposure Management System)

  • 권대철
    • 한국방사선학회논문지
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    • 제11권5호
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    • pp.321-328
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    • 2017
  • D-Shuttle (Chiyoda Technol Corporation, Tokyo, Japan) 선량계를 이용하여 개인피폭관리 및 자연방사선량의 모니터링을 위한 기초자료를 제공하는데 연구의 목적이 있다. D-Shuttle을 이용하여 선량을 산출하였다. 선량보고서에서 400 일 노출되었을 때에 1.346 mSv 이었고, 연간선량 (annual dose per year)은 1.228 mSv/year, 평균시간선량 (average dose per hour)은 $0.014{\mu}Sv/hr$ 이었다. 국내의 개인 외부피폭선량 (1.295 mSv/year =Korea average natural individual external dose), 국내의 연간부가선량 (additional dose per year)은 -0.0663 mSv/year 이다. D-Shuttle은 방사선모니터링을 위한 개인선량계로 방사선의 검출성능 우수한 기능, 실시간 방사선 피폭관리, 방사선 작업의 경보 기능, 효율적이고 사용이 편리한 개인 방사선선량의 피폭관리로 ALARA에 매우 유용한 선량계로 사용할 수 있다. 방사선작업종사자와 지역주민의 방사선모니터링 측정기기로 병원, 산업, 의료현장, 원전사고 지역과 비파괴 분야의 위험한 지역에서 방사선모니터링으로 활용될 수 있다.

High-radiation-exposure work in Korean pressurized water reactors

  • Changju Song;Tae Young Kong;Seongjun Kim;Jinho Son;Hwapyoung Kim;Jiung Kim;Jaeok Park;Hee Geun Kim;Yongkwon Kim
    • Nuclear Engineering and Technology
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    • 제56권5호
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    • pp.1874-1879
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    • 2024
  • Owing to strict radiation safety management in Korean nuclear power plants (NPPs), most radiation workers receive very low radiation doses, even lower than the annual dose limit for the general public. However, the occupational dose distribution indicates that some Korean NPP workers receive a relatively higher dose than the average dose. This inequity in radiation exposure could be reduced by providing customized radiation protection measures, such as dose constraints, to workers receiving relatively higher doses. In this study, dose normalization was performed to identify the highest radiation exposure work in Korean pressurized water reactors (PWRs). The results show that most of the occupational exposure in Korean PWRs occurs during the planned maintenance period. Finally, the three highest radiation exposure tasks in Korean PWRs were identified: nozzle dam installation and removal, eddy current testing, and man-way opening and closing.

국내 수처리시설 종사자 작업유형에 따른 외부피폭방사선량 평가 (Assessment of External Radiation Dose for Workers in Domestic Water Treatment Facility According to the Working Type)

  • 전성훈;이성연;김혁재;김민성;김광표
    • 방사선산업학회지
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    • 제17권2호
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    • pp.151-160
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    • 2023
  • The International Atomic Energy Agency (IAEA) proposes 11 industries that handle Naturally Occurring Radioactive Material (NORM) that are considered to need management. A water treatment facility is one of the above industries that takes in groundwater and produces drinking water through a water treatment process. Groundwater can accumulate natural radionuclides such as uranium and thorium in raw water by contacting rocks or soil containing natural radionuclides. Therefore, there is a possibility that workers in water treatment facilities will be exposed due to the accumulation of natural radionuclides in the water treatment process. The goal of this study is to evaluate the external radiation dose according to the working type of workers in water treatment facilities. In order to achieve the above goal, the study was conducted by dividing it into 1) analysis of the exposure environment, 2) measurement of the external radiation dose rate 3) evaluation of the external radiation dose. In the stage of analyzing the exposure environment, major processes that are expected to occur significantly were derived. In the measurement stage of the external radiation dose rate, a map of the external radiation dose rate was prepared by measuring the spatial radiation dose rate in major processes. Through this, detailed measurement points were selected considering the movement of workers. In the external radiation dose evaluation stage, the external radiation dose was evaluated based on the previously derived external radiation dose rate and working time. As a result of measuring the external radiation dose rate at the detailed points of water treatment facilities A to C, it was 1.90×10-1 to 3.75×100 μSv h-1, and the external radiation dose was analyzed as 3.27×10-3 to 9.85×10-2 mSv y-1. The maximum external radiation dose appeared during the disinfection and cleaning of activated carbon at facility B, and it is judged that natural radionuclides were concentrated in activated carbon. It was found that the external radiation dose of workers in the water treatment facility was less than 1mSv y-1, which is about 10% of the dose limit for the public. As a result of this study, it was found that the radiological effect of external radiation dose of domestic water treatment facility workers was insignificant. The results are expected to contribute as background data to present optimized safety management measures for domestic NORM industries in the future.

RADIATION DAMAGE IN THE HUMAN BODY ACUTE RADIATION SYNDROME AND MULTIPLE ORGAN FAILURE

  • AKASHI, MAKOTO;TAMURA, TAIJI;TOMINAGA, TAKAKO;ABE, KENICHI;HACHIYA, MISAO;NAKAYAMA, FUMIAKI
    • Nuclear Engineering and Technology
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    • 제38권3호
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    • pp.231-238
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    • 2006
  • Whole-body exposure to high-dose radiation causes injury involving multiple organs that depends on their sensitivity to radiation. This acute radiation syndrome (ARS) is caused by a brief exposure of a major part of the body to radiation at a relatively high dose rate. ARS is characterized by an initial prodromal stage, a latent symptom-free period, a critical or manifestation phase that usually takes one of four forms (three forms): hematologic, gastrointestinal, or cardiovascular and neurological (neurovascular), depending upon the exposure dose, and a recovery phase or death. One of the most important factors in treating victims exposed to radiation is the estimation of the exposure dose. When high-dose exposure is considered, initial dose estimation must be performed in order to make strategy decisions for treatment as soon as possible. Dose estimation can be based on onset and severity of prodromal symptoms, decline in absolute lymphocyte count post exposure, and chromosomal analysis of peripheral blood lymphocytes. Moreover, dose assessment on the basis of calculation from reconstruction of the radiation event may be required. Experience of a criticality accident occurring in 1999 at Tokai-mura, Japan, showed that ARS led to multiple organ failure (MOF). This article will review ARS and discuss the possible mechanisms of MOF developing from ARS.

Recent Trend of Occupational Exposure to Ionizing Radiation in Korea, 2015-2019

  • Lim, Young Khi
    • Journal of Radiation Protection and Research
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    • 제46권4호
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    • pp.213-217
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    • 2021
  • Background: Radiation exposure can occur as a result of occupational activities utilizing sources of radiation. The average level of occupational exposure is generally similar to the global average, but some workers receive more than this. In this study, the occupational exposure data for workers in Korea to check the recent trend of radiation exposure. Materials and Methods: The data collection and analysis are carried out by two separate periods based on the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) survey. One is the year 2003 to 2014 for a recent survey, and the other is 2015 to 2019. All available data were collected by annual reports from radiation dose registry organizations. Results and Discussion: The annual dose over the record level to the total workers did not change much compared with the total increasing number of workers in this period. The dose to the nuclear fuel cycle field has a tendency to decrease. It resulted from the efforts of radiation dose reduction with high technology introduced to this area. Also, it is important result that the radiation dose to the workers in radiography is remarkably reduced. Conclusion: The number of radiation workers and average doses were analyzed for occupational categories in Korea. It still needs cooperative efforts between the dose registry organizations for the efficient dose management of Korean radiation workers.

Analysis of Radiation Exposure Dose according to Location Change during Radiation Irradiation

  • Chang-Ho Cho;Jeong-Lae Kim
    • International Journal of Advanced Culture Technology
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    • 제12권2호
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    • pp.368-374
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    • 2024
  • During an X-ray examination, the beam of radiation is dispersed in many directions. We believe that managing radiation dose is about providing transparency to users and patients in the accurate investigation and analysis of radiation dose. The purpose of measuring the radiation dose as a function of location is to ensure that medical personnel using the equipment or participating in the operating room are minimally harmed by the different radiation doses depending on their location. Four mobile diagnostic X-ray units were used to analyze the radiation dose depending on the spatial location. The image intensifier and the flat panel detector type that receives the image analyzed the dose by angle to measure the distribution of the exposure dose by location. The radiation equipment used was composed of four units, and measuring devices were installed according to the location. The X-ray (C-arm) was measured by varying the position from 0 to 360 degrees, and the highest dose was measured at the center position based on the abdominal position, and the highest dose was measured at the 90° position for the head position when using the image intensifier equipment. The operator or medical staff can see that the radiation dose varies depending on the position of the diagnostic radiation generator. In the image intensifier and flat panel detector type that accepts images, the dose by angle was analyzed for the distribution of exposed dose by position, and the measurement method should be changed according to the provision of dose information that is different from the dose output from the equipment according to the position.

A Review of Organ Dose Calculation Tools for Patients Undergoing Computed Tomography Scans

  • Lee, Choonsik
    • Journal of Radiation Protection and Research
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    • 제46권4호
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    • pp.151-159
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    • 2021
  • Background: Computed tomography (CT) is one of the crucial diagnostic tools in modern medicine. However, careful monitoring of radiation dose for CT patients is essential since the procedure involves ionizing radiation, a known carcinogen. Materials and Methods: The most desirable CT dose descriptor for risk analysis is the organ absorbed dose. A variety of CT organ dose calculators currently available were reviewed in this article. Results and Discussion: Key common elements included in CT dose calculators were discussed and compared, such as computational human phantoms, CT scanner models, organ dose database, effective dose calculation methods, tube current modulation modeling, and user interface platforms. Conclusion: It is envisioned that more research needs to be conducted to more accurately map CT coverage on computational human phantoms, to automatically segment organs and tissues for patient-specific dose calculations, and to accurately estimate radiation dose in the cone beam computed tomography process during image-guided radiation therapy.