• Asian-Australasian Journal of Animal Sciences
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• v.21 no.12
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• pp.1779-1784
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• 2008

Seasonal changes in the concentration of free amino acids were determined monthly in plasma from the jugular blood of 50 thoroughbred racehorses that compete during the night between June and September and during the day between October and January. The concentration of most free amino acids remained relatively constant between June and January. However, those of glutamic acid, alanine, isoleucine and lysine tended to decrease and that of arginine (Arg) significantly decreased between July and September. The concentration of methionine (Met) gradually increased between June and September and significantly decreased thereafter. The concentration of 3-methylhistidine (3-MH) significantly increased between July and September and decreased thereafter. There were significant correlation between 3-MH and Arg. In conclusion, this study provided evidence of significant seasonal change in plasma 3-MH, Arg and Met of racehorses, and this was considered to relate to an environmental effect. Moreover, our study is the first to show 3-MH in plasma of racehorses affected by environmental change.

• Journal of Veterinary Clinics
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• v.31 no.4
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• pp.278-281
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• 2014

The object of this study was to determine rate of ability restoration after arthroscopic surgeries in Thoroughbred racehorses. The racehorses that under arthroscopic surgery due to be injured his limbs were studied during exercise or training at Busan Race Park from 2005 to 2010. Rate of arthroscopic surgical treatments was 1.4% (63/4642). The results of arthroscopic surgery for the removal of osteochondral fragments from 70 limbs in 63 horses are reported. Number of patients under arthroscopic surgery were 63 and 58 horses were recovered from the surgeries and 5 horses were in training or resting at the time of publication. Only 52 of 58 horses had previous race experiences before the surgeries. Success horses of returned to the same level of performance were 31 horses (59.6%) and failed horses were 21 horses (40.4%). Average resting periods in success and failed horses were 7 months and 8.8 months, respectively. Resting periods in success horses were shorter than failed horses.

• Korean Journal of Veterinary Research
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• v.28 no.2
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• pp.307-310
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• 1988

This experiment was carried out to provide the data of blood chemistry in use of application to clinical diagnosis in racehorses. Blood was collected from 30 racehorses(♀ 17, ♂ 13). Calcium, inorganic phosphorus, blood glucose, blood urea nitrogen, cholesterol, bilirubin, fibrinogen and ketone body in serum were analyzed as follows. 1. The values of calcium and inorganic phosphorus were maintained a certain level without much variation regardless of sex and species, Ca/P ratio was in the range of 3.13~3.35. 2. The value of blood glucose was 60 mg/100ml, Age and sex of racehorses make no difference in the value. 3. The value of blood urea nitrogen and total cholesterol showed a tendency to increase according to the age. Total cholesterol value was somewhat higher in male than in female. 4. The value of total bilirubin showed a tendency to increase according to the age. There was no difference between sexes in the value. 5. The value of fibrinogen showed no apparent difference with age and sex. 6. Ketone body was negative in all of the cases. 7. There was no variation in the species of the racehorses.

• Journal of Veterinary Clinics
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• v.15 no.2
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• pp.417-426
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• 1998

During the 5 years period(93-197) of Seoul racecourse Thoroughbred racing, 2i963 holies took an active part in Seoul Racecourse and 61,181 horses entered the racing.400 horses(305 : 1 time, 76 :2 times, 19 :3 times, total : 514 cases) had bled(EIPH) from their nostils after their races. Incidence of bleeding horses from the 21963 racehorses was 13.5%, and incidence of bleeding cases from the 61,181 horses was 0.84%. The average racing frequence (1.05 times/1 month) of bleeders was more than that(0.8 times/1 month) of total race-horses. There was tendency to higher incidence of bleeding at older in age, female in sex, England/ Ireland horses in origin, higher grade in performances heavier in body weight increased, larger in weight to be carried, mid or longer in racing distance, handicap race, spring in season. Relationship did not exist between bleeding and respiratory disease. These results suggested that frequent entering into the race should be controlled. And body weight regulation with conditioning is recommended far reducing incidence of EIPH. It is supposed to prevent bleeding that decrescent performance horses should not be entering long distance or handicap race.

• Journal of Animal Science and Technology
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• v.66 no.2
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• pp.425-437
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• 2024

Exercise plays an important role in regulating energy homeostasis, which affects the diversity of the intestinal microbial community in humans and animals. To the best of the authors' knowledge, few studies have reported the associations between horse gut microbiota along with their predicted metabolic activities and the athletic ability of Jeju horses and Thoroughbreds living in Korea. This study was conducted to investigate the association between the gut microbiota and athletic performance in horses. This study sequenced the V3 and V4 hypervariable regions of the partial 16S rRNA genes obtained from racehorse fecal samples and compared the fecal microbiota between high- and low-performance Jeju horses and Thoroughbreds. Forty-nine fecal samples were divided into four groups: high-performance Jeju horses (HJ, n = 13), low-performance Jeju horses (LJ, n = 17), high-performance Thoroughbreds (HT, n = 9), and low-performance Thoroughbreds (LT, n = 10). The high-performance horse groups had a higher diversity of the bacterial community than the low-performance horse groups. Two common functional metabolic activities of the hindgut microbiota (i.e., tryptophan and succinate syntheses) were observed between the low-performance horse groups, indicating dysbiosis of gut microbiota and fatigue from exercise. On the other hand, high-performance horse groups showed enriched production of polyamines, butyrate, and vitamin K. The racing performance may be associated with the composition of the intestinal microbiota of Jeju horses and Thoroughbreds in Korea.

• Journal of Veterinary Clinics
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• v.11 no.1
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• pp.347-358
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• 1994

This study was peformed to investigate the morbidity of nutritional secondary hyperparathyroidism(NSH) caused by imbalance of Ca and p, and related athletic disease in Cheju pony racehorse. The seventeen horses with clinical signs among 33 NSH affected, administered CaCO$_3$(34 g) and Vita-rinka1(120 g) respectively for 40 days. The results were asd follows; Morbidity of NSR was 33 among 47 horses, and it was caused by the deficiency of Ca in 32 horses. In a case, level of Ca was norm질 although P was high. There was no case of Ca deficiency with P excess. Among 33 NSH affected horses, 13 were subclinical and 20 were clinical types with severe lameness in 6 and transient lameness in 14. Although there was no difference in bone density between transient lameness and normal horses on radiography, among six horses wlth severe lameness two showed hyperplasia at periosteum, one had low density of phalanges and metacarpal bones, and thin cortex. and there with fracture at carpus, nivicular bone and proximal sesamoids. The levels of FECa and FEP were recovered after CaCO$_3$ administration in 2 horses among ten, and after Vita-rinkal in all of seven. The clinical signs were disappeared in slx horses among ten CaCO$_3$ treated, and in five among seven Vita-rinkal treated. There were no differences on radiography in bone density and thickness of cortex on 14 horses with transient lameness. Three horses with severe signs were recovered to normal bone density and thickness of cortex, and there was no significant difference between two groups. In summary, the morbidity of NSH in Cheju pony racehorses was relatively high because of deficiency of Ca. Constant admistration of Ca supplements is desirable to treat and prevent athletic disease development in Cheju racehorses.

• Korean Journal of Veterinary Research
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• v.37 no.3
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• pp.525-532
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• 1997

The hoof parameters - hoof angle, toe length, heel length, hoof width, hoof length, heel width, hoof circumference - of 1372 Thoroughbred racehorses in Seoul racecourse were measured. Each parameter was compared with the racing time. The parameters were as follows: fore hoof angle $50.1{\pm}0.09^{\circ}$, hind hoof angle $50.1{\pm}0.08^{\circ}$; fore toe fength $82.8{\pm}0.21mm$, hind toe length $88.8{\pm}0.23mm$; fore heel length $28.6{\pm}0.19mm$, hind heel length $24.5{\pm}0.19mm$; fore hoof width $130.9{\pm}0.30mm$, hind hoof width $125.7{\pm}0.28mm$; fore hoof length $133.3{\pm}0.22mm$, hind hoof length $28.1{\pm}0.22mm$; fore heel width $61.2{\pm}0.32mm$, hind heel width $67.9{\p}0.35mm$; fore hoof circumference $264.2{\pm}0.48mm$, hind hoof circumference $253.8{\pm}0.40mm$. Apart from the hoof angle, the hoof parameters increased in proportion to the body weight. The parameters of forelimbs affected the racing time more than those of hindlimbs. The correlation between hoof parameters and racing time was shown more in short-distance race (1000M) than in long-distance race(2200M). The parameters that had correlation with racing time were hoof width, hoof length, heel width of forelimbs and heel width of hindlimbs.

• Journal of Veterinary Clinics
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• v.40 no.3
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• pp.209-214
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• 2023

A 3-year-old Thoroughbred gelding was referred to the Jeju National University Equine Hospital with prolonged unilateral nasal discharge for several months. A sinus cyst was suspected based on the history, symptoms, endoscopic findings, and radiographic results. Computed tomography (CT) scan revealed that the cyst (7.5 × 8.0 × 10.0 cm) was located between the rostral maxillary sinus and the frontal sinus, causing distortion and remodeling of the overlying bones, swelling of the overlying cutaneous tissues, and a slight deviation of the nasal septum. Standing surgery under sedation was decided to remove the cyst. A frontonasal bone flap was performed using an oscillating bone saw, and the cyst filled with pus was removed. To support the approach to the maxillary sinus, trephination was performed. The horse was treated with sinus lavage via catheterization, nebulization, antibiotics, and nonsteroidal anti-inflammatory drugs. The horse was discharged 18 days after the surgery without signs of any complication. This case showed that a CT scan could be a valuable tool for the diagnosis and subsequent surgical management of paranasal sinus cysts in horses. Also, the frontonasal bone flap was useful for exposing and removing the large-sized of cyst in the paranasal sinus.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.11
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• pp.1633-1642
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• 2017

Objective: Evaluation of exercise effects in racehorses is important in horseracing industry and animal health care. In this study, we compared metabolic patterns between before and after exercise to screen metabolic biomarkers for exercise effects in thoroughbreds. Methods: The concentration of metabolites in muscle, plasma, and urine was measured by $^1H$ nuclear magnetic resonance (NMR) spectroscopy analysis and the relative metabolite levels in the three samples were compared between before and after exercise. Subsequently, multivariate data analysis based on the metabolic profiles was performed using orthogonal partial least square discriminant analysis (OPLS-DA) and variable important plots and t-test was used for basic statistical analysis. Results: From $^1H$ NMR spectroscopy analysis, 35, 25, and 34 metabolites were detected in the muscle, plasma, and urine. Aspartate, betaine, choline, cysteine, ethanol, and threonine were increased over 2-fold in the muscle; propionate and trimethylamine were increased over 2-fold in the plasma; and alanine, glycerol, inosine, lactate, and pyruvate were increased over 2-fold whereas acetoacetate, arginine, citrulline, creatine, glutamine, glutarate, hippurate, lysine, methionine, phenylacetylglycine, taurine, trigonelline, trimethylamine, and trimethylamine N-oxide were decreased below 0.5-fold in the urine. The OPLS-DA showed clear separation of the metabolic patterns before and after exercise in the muscle, plasma, and urine. Statistical analysis showed that after exercise, acetoacetate, arginine, glutamine, hippurate, phenylacetylglycine trimethylamine, trimethylamine N-oxide, and trigonelline were significantly decreased and alanine, glycerol, inosine, lactate, and pyruvate were significantly increased in the urine (p<0.05). Conclusion: In conclusion, we analyzed integrated metabolic patterns in the muscle, plasma, and urine before and after exercise in racehorses. We found changed patterns of metabolites in the muscle, plasma, and urine of racehorses before and after exercise.

• Journal of Practical Agriculture & Fisheries Research
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• v.17 no.1
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• pp.125-132
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• 2015

The report about equine anesthesias in Korea are very rare. This paper aimed at the mortality rate during anesthesia in Thoroughbred horses at Equine Hospital of Busan Race Park, KRA in South Korea from 2005 to 2010. Drugs used in anesthesia was IV injection of detomidine hydrochloride (0.01 mg/kg) or xylazine(0.5mg/kg) for sedation and premedication, Guaifenesin(50-100 mg/kg) for muscle relaxation, ketamine hydrochloride(2 mg/kg) for induction of anaesthesia and Inhalational isoflurane(1.3-1.5 %) to maintain anesthesia. Total number of anesthetic cases was 190, 150 of inhalational anesthesia and 40 of general anesthesia, repectively. The purpose of anesthesia was highest in the disorder of musculoskeletal system, followed by urogenital system and respiratory system Mortality case due to anesthesia was one during arthroscopic surgery for removal of osteochondral chip fragments. The time of anesthesia was 150 min, fatal sign was hypoxemia and the reason was improper machine operation of the anesthetist. In conclusion, the perianesthetic mortality rate during anesthesia in Thoroughbred horses at Busan Race Park was 0.52%(1 death per 190 anesthetics).