• Preventive Nutrition and Food Science
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• 제1권2호
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• pp.196-202
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• 1996

The effect of cooking(boiling, steaming and baking0and drying on the cholesterol content and formation of oxidized cholesterols in quid(Japanese flying squid, Todarodes pacificus) was studied. Cholesterol content of live squid meat varied with the portion sampled, and results from spectrophotometric assay ranged from 263.2mg/1..g(mantle) to 315.8mg/100g(tentacle). The cholesterol levels analyzed by gas chromatography(GC) for squid samples were lower by 7% of total cholesterol for live squid meat and 24% for processed meat than those results by spectrophotometric assay. Cooking resulted in the decrease of the initial total cholesterol content of raw meat from 10%(boiling for 5min.) to 25%(steaming for 5min.) The amounts of cholesterol remaining after baking were 68% for microwave oven samples and 64% for convection oven samples. Drying of raw tissue caused the greater reduction in cholesterol content than cooking but showed no significant difference in samples stored for 6 weeks at 4$^{\circ}C$ and 2$0^{\circ}C$. Raw squid meats contained essentially no oxidized cholesterols, while the 22-hydroxychoesterol was detected in frozen meats. The additional oxidized cholesterols as cholestane-triol was indentified with 22-hydroxycholesterols in cooked samples. Sun dried meat stored at 4一 and 2$0^{\circ}C$ for 6 weeks had the three kinds of oxidized cholesterols such as 22-hydroxycholesterol, cholesta-3,5-dien-7-one and cholestane-triol.

• Biomolecules & Therapeutics
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• 제5권3호
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• pp.253-259
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• 1997

The effect of corticosteroid on the diabetic pregnant rats and their fetuses was investigated. Streptozotocin (STB) was injected into the pregnant rats on the fifth day of pregnancy. Dexamethasone (DXM) was injected into the pregnant rats on the 17th, 18th, 19th and 20th days of pregnancy In prenatal rats, the body weight, an abortion rate, number of fetus, the ratio of lecithin/sphingomyelin (L/S) and the levels of blood glucose and phosphatidylglycerol (PG) were determined. In the postnatal rats, the body weight, the levels of blood glucose, fetal number, stillbirth rate, an organ weight and the levels of hepatic glycogen, protein and triglyceride were determined. The body weight of fetuses was lower in the DXM group and higher in the STZ group than the those of control group. Blood glucose of fetuses produced hypoglycemia in the STZ group compared with the control group. A significant increase in the abortion and stillbirth rates was observed in STZ group. The levels of glycogen, protein and triglyceride in fetus liver and the weight of pancreas were significantly increased in the 572 and STZ+DXM groups compared with the control group. The L/S ratio and the level of PG in the amniotic (quid were significantly decreased in STZ group compared with the control group, whereas those of the STZ+DXM group were similar to the control group. It has been observed that corticosteroid administration on the STZ-induced diabetic rats during final stage of pregnancy can prevent the respiratory depression syndrome of neonatal rats.

• 한국세라믹학회지
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• 제39권6호
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• pp.566-569
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• 2002

일반적으로 Pb-계 복합 perovskite형 산화물들은 그 제조과정에서 중간상으로 알려진 pyrochore상을 통하여 최종적으로 합성된다. 본 연구에서는 Pb(Fe$_{1}$2/Nb$_{1}$2/)O$_3$를 대상으로 하여 고유전율, 고순도, 입자크기 및 저온 소결에 알맞은 Pb(Fe$_{1}$2/Nb$_{1}$2/)O$_3$분말을 초임계 유체의 장점과 autoclave내의 분리 반응 실험으로 285$^{\circ}C$,7.2MPa의 조건하에서 제조하였고, 제조되어진 분말들의 제반 특성들에 대하여 조사하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권10호
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• pp.5087-5090
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• 2012

Oral cancer is a common site of head and neck cancer, and is relatively frequent in Northeast Thailand. The objective of this hospital-based, case-control study was to determine associations with risk factors. A total of 104 oral cancer cases diagnosed between July 2010 and April 2011 in 3 hospitals were matched with control subjects by age, sex and hospital. Data were collected by personal interview. There were significant associations between oral cancer and tobacco smoking (OR=4.47; 95%CI=2.00 to 9.99), alcohol use among women (OR=4.16; 95%CI=1.70 to 10.69), and betel chewing (OR=9.01; 95%CI=3.83 to 21.22), and all three showed dose-response effects. Smoking is rare among Thai women (none of the control women were smokers), but betel chewing, especially among older women, is relatively common. We did not find any association between practicing oral sex and oral cancer.

• Parasites, Hosts and Diseases
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• 제30권1호
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• pp.53-58
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• 1992

환자는 54세 광부로 1991년 1월 낙반사고로 인해 가벼운 골반 골절상을 받았었고, 골절상은 완치되었으나 설사가 지속하고 체중이 심하게 감소하였다. 발병 약 9 개월만에 시행한 대변검사 및 조직 검사에서 분선충중(strongyloidiasis), 포자충중(isosporiasis) 및 인형 세포거대바이러스(heman cytomegalovirus)에 감염된 사실이 확인되었다. Albendazole로 치료하였으나 약 2개월 후 근로복지공사 장성병원에서 난치 상환 하에 퇴원하였으며, 퇴원 1주 후 사망하였다.

• 디자인학연구
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• 제14권3호
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• pp.165-176
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• 2001

기업들은 고객에게 효과적으로 어필될 수 있는 기업이미지를 구축하기 위하여 Corporate Identity 작업을 계속 해 왔다 특히 매일 수없이 증가되고 있는 인터넷 사이트들 속에서 타 기업과의 차별화 된 이미지구축 노력은 더욱 지열 해 질 전망이다. 그러나 고전적 의미의 CI 프로그램들은 주로 인쇄매체 등의 오프라인에 적용하기 위한 개념으로 개발되었기 때문에 새로운 미디어에 대한 재적용이 불가피할 것으로 보인다. 특히 인쇄매체의 대명사이던 신문도 방대한 데이터베이스 구축과 빠른 업 데이트가 가능한 동시에 독자와 상호 인터렉티브한 기능을 가진 인터넷의 제 특성을 활용하여 그 영역을 온라인으로 넓혀가고 있으나, 오프라인과 일관성 있는 이미지 구축에는 아직 어려움이 많은 것이 현실이다. 이러한 견지에서 본 연구는 뉴스사이트가 인쇄매체와의 동질성을 유지하면서 웹 상에서 특성화될 수 있는 Identity전략과 그 방향을 모색해 보고자 한다

• Nuclear Engineering and Technology
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• 제53권5호
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• pp.1519-1523
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• 2021

Radioactive iodine (¹³¹I) released from nuclear power plants has been a critical environmental concern for workers. The effective trapping of radioactive iodine isotopes from the off-gas stream generated from nuclear facilities is an important issue in radioactive waste treatment systems evaluation. Numerous studies on retaining methyl iodide (CH₃I¹³¹) by impregnated activated carbons under the high content of moisture have been extensively studied so far. But there have been no good results on how to remove methyl iodide at high humid conditions up to now. A new challenge is to introduce other promising impregnating chemical agents that are able to uptake enough radioactive methyl iodide under high humid conditions. In order to develop a good removal efficiency to control radioiodine gas generated from a high humid process, activated carbons (ACs) impregnated with triethylene diamine (TEDA) and qinuclidine (QUID) were prepared. In addition, the removal efficiencies of the activated carbons (ACs) under humid conditions up to 95% RH were evaluated by applying the standard method specified in ASTM-D3808. Quinuclidine impregnated activated carbon showed a much higher decontamination factor above 1,000, which is enough to meet the regulation index for the iodine filters in nuclear power plants (NPPs).

• 응용통계연구
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• 제29권7호
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• pp.1311-1327
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• 2016

본 논문에서는 종말 사건에 대한 정보는 주어져 있지만 중간 사건이 구간 중도절단되었거나 연구 기간 도중에 추적이 끊겨 중간 사건의 발생 유무를 모르는 준 경쟁 위험 자료에 다중상태모형을 적용하여 모수를 추정하는 방법을 제안하였다. 이를 위해 상태 간 전이 강도는 정규 프레일티를 랜덤효과로 가진 Cox 비례위험모형을 따른다고 가정하였다. 다섯 가지 상태를 가진 다중상태모형에서 가능한 여섯 가지 경로별로 조건부 우도를 정의하였고 주변 우도를 구하기 위해 조정 가우스 구적법을 적용하였으며 뉴튼-랩슨 방법으로 최적 해를 구하였다. 모수의 95% 신뢰구간 포함률을 통해 제안한 방법의 소표본 성질을 살펴보기 위해 모의실험을 수행하였으며, Persones $Ag{\acute{e}}es$ Quid(PAQUID) 자료 (Helmer 등, 2001)에 제안한 모형을 적용하고 그 결과를 해석하였다.

• 한국식생활문화학회지
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• 제14권2호
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• pp.67-81
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• 1999

The present study was surveyed for the normal meal and particular folk meal in east cot area in Kyungpook province, Pohang, Youngduk, and Uljin areas. The results are as below: Most subjects for surveying were 30-40 years old and permanent residents in those areas. For the normal meal, the boiled rice was the top main dishes among 18 main dishes. The folloing upper five main dishes were boiled bean rice, boiled barley rice, boiled miscellaneous cereals rice, noodles, and Bbimbab (miced rice with cooked various vegetables and meats). Less frequent main dishes were raw fish Bbimbab and the various fish soups etc. The two upper side dishes, out of 17 surveyed ones, were kimchi and soybean paste soup. Twelve dishes(about 70%) out of 17 side dishes, the loach soup, the marinated and fermented raw fishes (fish Sikhae'), the baked mackerel, the pickled fishes, the friedsardine, the green seaweed, and the quid, etc. were made from the sea products. For the particular folk meal, about 30 kinds of the specific folk food items of this area were surveyed: Gudungchi' Sikhae', which was made with seaweed, out of the 11 kinds of fish Sikhae', raw fish(Whae') in water, Sigumjang', a salty agar, a steamed seaweed which was covered with the flour or bean power the various kinds of fish soups, the various kinds of fish stews were the particular folk side dishes in these areas. The dietary habit in these east coast areas were affected by the various sea food products, the fishes and the seaweeds, which were acquired easily through four season in these area.

• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.9955-9960
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• 2014

Background: Promoter hypermethylation is a common event in human cancer. O6-methylguanine-DNA methyltransferase (MGMT) is a gene involved in DNA repair, which is methylated in a variety of cancers. We aimed to explore the methylation status of MGMT gene among the North Eastern population where esophageal cancer incidence and exposure to carcinogens like nitrosamines is high. Materials and Methods: A total of 100 newly diagnosed esophageal cancer cases along with equal number of age, sex and ethnicity matched controls were included in this study. Methylation specific PCR was used to determine the MGMT methylation status in serum samples. Results: Aberrant promoter methylation of the MGMT gene was detected in 70% of esophageal cancer cases. Hypermethylation of MGMT gene was found to be influenced by environmental factors like betel quid and tobacco which contain potent carcinogens like nitrosamines. Tobacco chewing and tobacco smoking habit synergistically with MGMT methylation elevated the risk for esophageal cancer development [adjusted OR=5.02, 95% CI=1.35-18.74; p=0.010 for tobacco chewing and Adjusted OR=3.00, 95% CI=1.22-7.36; p=0.014 for tobacco smoking]. Conclusions: Results suggest that the DNA hypermethylation of MGMT is an important mechanism for MGMT gene silencing resulting in esophageal cancer development and is influenced by the environmental factors. Thus MGMT hypermethylation can be used as a biomarker for esophageal cancer in high incidence region of North East India.