• Title/Summary/Keyword: quantitative variation

검색결과 709건 처리시간 0.03초

CT-based quantitative evaluation of radiation-induced lung fibrosis: a study of interobserver and intraobserver variations

  • Heo, Jaesung;Cho, Oyeon;Noh, O Kyu;O, Young-Taek;Chun, Mison;Kim, Mi-Hwa;Park, Hae-Jin
    • Radiation Oncology Journal
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    • 제32권1호
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    • pp.43-47
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    • 2014
  • Purpose: The degree of radiation-induced lung fibrosis (RILF) can be measured quantitatively by fibrosis volume (VF) on chest computed tomography (CT) scan. The purpose of this study was to investigate the interobserver and intraobserver variability in CT-based measurement of VF. Materials and Methods: We selected 10 non-small cell lung cancer patients developed with RILF after postoperative radiation therapy (PORT) and delineated VF on the follow-up chest CT scanned at more than 6 months after radiotherapy. Three radiation oncologists independently delineated VF to investigate the interobserver variability. Three times of delineation of VF was performed by two radiation oncologists for the analysis of intraobserver variability. We analysed the concordance index (CI) and inter/intra-class correlation coefficient (ICC). Results: The median CI was 0.61 (range, 0.44 to 0.68) for interobserver variability and the median CIs for intraobserver variability were 0.69 (range, 0.65 to 0.79) and 0.61(range, 0.55 to 0.65) by two observers. The ICC for interobserver variability was 0.974 (p < 0.001) and ICCs for intraobserver variability were 0.996 (p < 0.001) and 0.991 (p < 0.001), respectively. Conclusion: CT-based measurement of VF with patients who received PORT was a highly consistent and reproducible quantitative method between and within observers.

GIS 기반의 리스크 요인을 고려한 노선 계획 (Route Planning Considering Risk Factors Based on GIS)

  • 노태호;장호식
    • 한국도로학회논문집
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    • 제8권3호
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    • pp.1-19
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    • 2006
  • 본 연구는 지형공간정보체계 기반에서 리스크 요인의 변동을 고려한 의사결정을 적용하여 정량적 평가를 수행할 수 있는 기법을 연구한 결과, 다음과 같은 결론을 얻을 수 있었다. 첫째, 리스크 요인의 변동을 고려한 의사결정을 통하여, 기존의 노선에 대한 평가를 정량적인 값으로 산출 할 수 있었으며, 이를 신설될 노선에 대하여 적용하면 도로 계획 및 기본 설계시에 객관적이고 신뢰성 있는 설계를 할 수 있을 것으로 판단된다. 둘째, 리스크 요인의 변동을 고려한 평면선형과 종단선형을 지형공간정보체계 기반에서 쉽게 추출할 수 있었으며, 도로의 계획에서 의사결정에 의한 신속한 3차원 선형 계획 및 분석이 가능하다. 셋째, 본 연구에서 구축된 정량적 평가 시스템을 이용하면 노선선정이 자동화됨으로서, 비교적 많은 비교안을 짧은 시간 내에 리스크 분석을 할 수 있으므로, 도로설계기술발전에 기여 할 수 있다고 판단된다.

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GC에서 검출한계 결정을 위한 새로운 접근 방법에 대한 연구 (Study on the new approaching method to determine limit of detection by gas chromatography)

  • 오도석;신경애;이지아;임종호;신미선
    • 한국산업보건학회지
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    • 제20권4호
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    • pp.217-224
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    • 2010
  • The purity methods to determine LOD/LOQ using standard deviation of the residual, intercept and blank by IUPAC and ACS describe many of the pitfalls and pose significant challenges to analytical chemists. Therefore, the aim of this study is the development of the simple, easy, convenient and statistically significant method to determine LOD in quantitative analysis of organic solvents by GC. The new approaching method by linearization in the given concentration range used coefficient of variation ; ${\sigma}_{n-1}$/S(standard deviation, ${\sigma}_{n-1}$ and average, S) of sensitivity(Response/concentration). The comparison of results among the purity methods(IUPAC and ACS) and the linearization have been fulfilled the F-test for standard deviations and t-test for LOD range values. The results of F-test and t-test are satisfied within 95 % confidence level, respectably. The LOD values determined by the new procedure are n-Hexane 0.0116 mg/$m^3$, Toluene 0.0807 mg/$m^3$, and o-Xylene 0.0494 mg/$m^3$. Because the standard deviation of the residual, intercept and blank and the slope of calibration curve are not calculated and the new approaching method use the coefficient of variation of sensitivity by linearization, this new method is simple, easy, convenient and statistically significant. In future, many chemical analysts will expect to applicate and routinely use this method in the all quantitative analysis.

인디고 분석 표준액의 제조법 및 쪽 육성계통의 인디고 함량변이 (Preparation Method of Indigo Standard Solution and Variation of Indigo Contents in Blue Dye Extract from Breeding Lines of Persicaria tinctoria H. Gross)

  • 김성주;고재형;박시형;김명석;김관수
    • 한국약용작물학회지
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    • 제21권3호
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    • pp.213-219
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    • 2013
  • This study was carried out to find out the optimum method of preparation of indigo standard solution and its stability, and to investigate the indigo contents in Niram, blue dye extract, from a total of 7 indigo plants and 34 breeding lines of Persicaria tinctoria H. Gross. Proper solvent for indigo standard was dimethyl sulfoxide (DMSO), and appropriate concentration was 1 mg of indigo in 10 mL of DMSO. Absorbance value of UV/Vis Spectrophotometer at 620 nm of standard solution was changed decreasingly 12 hours after the preparation of standard solution irrespective of the storage conditions such as temperature and light. Average value of absorbance of 8-fold diluted standard solutions prepared daily during 16 days was $0.210{\pm}0.005$, indicating the powder of indigo compound was stable chemically. Calibration curve was made for quantitative analysis of indigo of 7 Niram samples, and indigo contents ranged from 0.69% to 18.76% showing relatively larger variation. Across all 34 breeding lines, the range of indigo content was from 7.9 mg to 56.4 mg per 100 g of fresh leaves, averaging 25.2 mg of indigo content and showing a 47.7% coefficient of variation.

Analysis on the special quantitative variation of dot model by the position transform

  • Kim, Jeong-lae;Kim, Kyung-seop
    • International Journal of Advanced Culture Technology
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    • 제5권3호
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    • pp.67-72
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    • 2017
  • Transform variation technique is constituted the vibration status of the flash-gap recognition level (FGRL) on the distribution recognition function. The recognition level condition by the distribution recognition function system is associated with the scattering vibration system. As to search a position of the dot model, we are consisted of the distribution value with character point by the output signal. The concept of recognition level is composed the reference of flash-gap level for variation signal by the distribution vibration function. For displaying a variation of the FGRL of the maximum-average in terms of the vibration function, and distribution position vibration that was the a distribution value of the far variation of the $Dis-rf-FA-{\alpha}_{MAX-AVG}$ with $5.74{\pm}1.12$ units, that was the a distribution value of the convenient variation of the $Dis-rf-CO-{\alpha}_{MAX-AVG}$ with $1.64{\pm}0.16$ units, that was the a distribution value of the flank variation of the $Dis-rf-FL-{\alpha}_{MAX-AVG}$ with $0.74{\pm}0.24$ units, that was the a distribution value of the vicinage variation of the $Dis-rf-VI-{\alpha}_{MAX-AVG}$ with $0.12{\pm}0.01$ units. The scattering vibration will be to evaluate at the ability of the vibration function with character point by the distribution recognition level on the FGRL that is showed the flash-gap function by the recognition level system. Scattering recognition system will be possible to control of a function by the special signal and to use a distribution data of scattering vibration level.

교류 피복 아크 용접에 있어서 아크 안정성의 정량적 평가에 관한 연구 (A Study on the Quantitative Evaluation of Arc Stability in AC SMAW)

    • Journal of Welding and Joining
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    • 제16권4호
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    • pp.125-135
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    • 1998
  • The shielded metal arc welding (SMAW) by AC power source was performed to evaluate the arc stability by arc monitoring and analysing. In this study, the arc stability index was evaluated quantitatively by using he coefficient of resistance variation for welding time. This coefficient was obtained for the long time (20sec.) by analysing the waveforms of welding current, voltage and resistance. The coefficient was applied to indicate numerically the variation level of arc length and the degree of arc extinction. Using the coefficient of resistance variation in practical welding, the arc stability of the high titanium oxide electrode (KS E4313) turned out to be better than that of the low hydrogen electrode (KS E4316). In evaluating the skill level of welders by the coefficient, the horizontal fillet weaving welding became clear to be very discriminating because the higher level welder could weave in keeping constant arc length, but the lower level welder showed the characteristics of weaving with the unstable arc length. And it was confirmed that the welding defects as blow holes was formed when the arc stability index were high.

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우리나라 연최대치 강우량 계열 및 확률강우량의 변화 특성 (Variation Characteristics of Annual Maximum Rainfall Series and Frequency-Based Rainfall in Korea)

  • 김재형
    • 한국습지학회지
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    • 제4권2호
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    • pp.43-56
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    • 2002
  • About 12 rain gauge stations of Korea, annual maximum rainfall series of before and after 1980 whose durations are 1, 2, 3, 6, 12, 24, 48, 72 hours respectively were composed and statistical characteristics of those time series were calculated and probability rainfall were estimated by L-moment frequency analysis method and compared each other in order to investigate the recent quantitative rainfall variations. And also, distribution curves of each statistical variations for each duration were constructed by using Kigging method to look into spacial rainfall variation aspects. As a result, We could confirm recent rainfall increase in the South Korea. And spatial increase pattern of standard deviation and frequency rainfall appeared analogously each other. 1n the cases of comparatively short rainfall duration, we could see relatively low increase or decrease tendency in Chungchong Province, Cholla-bukdo, Cholla-namdo eastern part, Kyongsang-namdo western part area. While, variations happened great1y in seaside district of east coast, southwest seashore, Inchon area etc. In the cases of longer durations relatively low increase was showed in southern seashore such as Yeosoo area and as distance recedes from this area, showed gradually augmented tendency. The aspect of mean looks similar tendency of above except that the variation rate of almost seaside district are big in the case of shorter durations. In addition, rainfall increases of short durations which became the center of hydrologist and meteorologist are unconfirmed in this study.

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在來種마늘의 量的形質에 대한 遺傳變異와 相關 (Genitic Variability and Correlation of Quantitative Characters in Local Garlic Cultivars)

  • 김정선
    • 한국자원식물학회지
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    • 제11권3호
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    • pp.264-271
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    • 1998
  • This study was conducted to investigate morphological characteristics of Korean local garlic varieties and to define the genetic variability and the correlations amongthe characters associated with yield. The plant height, the leaf sheath diameter, the nubmer of leaves, and bulb weight were significantly increased in the garlic plants from heavier seed bulbs. The proportation of six clove bulbs was more than 60% in Seosan variety and this was not realted with the number of cloves in seed bulb. While more than 70% bulbs in Jeoksung and Danyang varieties cultivated in paddy field were composed of 6 or 7 cloves, majority of the bulbs of Euisung and Danyang varieties cultivated in upland were composed of bulbs with 7 cloves or more. The highest genotypic coefficient of variation (GCV) and phenotypic coefficient of variation (PCV) were observed in bulb weight. GCV and PCV also showed high value in leaf sheath diameter. Thus, there is a greater scope for selection of these characters. The small difference between PCV and GCV values in plant height indicates that the environmental influence would be limited in this character. High heritability was observed of plant height (56.76%) and bulb weight (45.95%). And the weight per bulb (34.24%) exhibited highest genitic advance followed by leaf sheath diameter (18.8%) and plant height (9.61%), and those would be the ideal characters for selelction.

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Strain elastography of tongue carcinoma using intraoral ultrasonography: A preliminary study to characterize normal tissues and lesions

  • Ogura, Ichiro;Sasaki, Yoshihiko;Sue, Mikiko;Oda, Takaaki
    • Imaging Science in Dentistry
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    • 제48권1호
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    • pp.45-49
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    • 2018
  • Purpose: The aim of this study was to evaluate the quantitative strain elastography of tongue carcinoma using intraoral ultrasonography. Materials and Methods: Two patients with squamous cell carcinoma (SCC) who underwent quantitative strain elastography for the diagnosis of tongue lesions using intraoral ultrasonography were included in this prospective study. Strain elastography was performed using a linear 14 MHz transducer (Aplio 300; Canon Medical Systems, Otawara, Japan). Manual light compression and decompression of the tongue by the transducer was performed to achieve optimal and consistent color coding. The variation in tissue strain over time caused by the compression exerted using the probe was displayed as a strain graph. The integrated strain elastography software allowed the operator to place circular regions of interest (ROIs) of various diameters within the elastography window, and automatically displayed quantitative strain (%) for each ROI. Quantitative indices of the strain (%) were measured for normal tissues and lesions in the tongue. Results: The average strain of normal tissue and tongue SCC in a 50-year-old man was 1.468% and 0.000%, respectively. The average strain of normal tissue and tongue SCC in a 59-year-old man was 1.007% and 0.000%, respectively. Conclusion: We investigated the quantitative strain elastography of tongue carcinoma using intraoral ultrasonography. Strain elastography using intraoral ultrasonography is a promising technique for characterizing and differentiating normal tissues and SCC in the tongue.

Evaluation of Potential Reference Genes for Quantitative RT-PCR Analysis in Fusarium graminearum under Different Culture Conditions

  • Kim, Hee-Kyoung;Yun, Sung-Hwan
    • The Plant Pathology Journal
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    • 제27권4호
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    • pp.301-309
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    • 2011
  • The filamentous fungus Fusarium graminearum is an important cereal pathogen. Although quantitative realtime PCR (qRT-PCR) is commonly used to analyze the expression of important fungal genes, no detailed validation of reference genes for the normalization of qRT-PCR data has been performed in this fungus. Here, we evaluated 15 candidate genes as references, including those previously described as housekeeping genes and those selected from the whole transcriptome sequencing data. By a combination of three statistical algorithms (BestKeeper, geNorm, and NormFinder), the variation in the expression of these genes was assessed under different culture conditions that favored mycelial growth, sexual development, and trichothecene mycotoxin production. When favoring mycelial growth, GzFLO and GzUBH expression were most stable in complete medium. Both EF1A and GzRPS16 expression were relatively stable under all conditions on carrot agar, including mycelial growth and the subsequent perithecial induction stage. These two genes were also most stable during trichothecene production. For the combined data set, GzUBH and EF1A were selected as the most stable. Thus, these genes are suitable reference genes for accurate normalization of qRT-PCR data for gene expression analyses of F. graminearum and other related fungi.