• Proceedings of the Korean Environmental Health Society Conference
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• 2005.06a
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• pp.326-329
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• 2005

A worker who grinded the inner parts of camshafts for automobile engines using water-soluble metalworking fluid (MWF) for 14 years was diagnosed with sinusitis. We postulated that the outbreak of sinusitis could be associated with exposure to microbes contaminated in water-soluble MWF during the grinding operation. To suggest responsible agents for this outbreak, quantitative exposure assessment for chemical and biological agents and prevalence of work-related respiratory symptoms by questionnaire were studied. The exposure ranges of MWF mist (0.59 $mg/m^3$to 2.12 $mg/m^3$) measured during grinding exceeded 0.5 $mg/m^3$ of the recommended exposure limit (REL). Grinder's exposures to bacteria, fungi and endotoxins were also generally higher than not only the proposed standards, but also those reported by several studies to identify the cause of respiratory effects. Statistical test indicated that the prevalence rate of reported symptoms related to nasal cavities showed no significant differences among the operations. Evaluation on grinding operation characteristics and quantitative exposure assessment indicated that repeated exposure to MWF mist including microbes contaminated from the use of water-soluble MWF may cause respiratory diseases like sinusitis or at least increase susceptibility to the development of sinusitis

• Korean Journal of Poultry Science
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• v.21 no.2
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• pp.73-82
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• 1994

A study was conducted to develop a new analytical method to quantitate chicken dietary fiber (CDF). Four types of grain diets and 2 types of forages were used. Three broiler chicks at eight weeks of age were used in the Latin square design to estirnate the in vivo digestibility. Six quantitative analytical methods (Southgate method, total dietary fiber or TDF, acid detergent fiber or ADF, neutral detergent fiber or NDF, crude fiber or CF) including CDF were compared in this study. ADF, NDF and CF contained the lowest amount of the unavailable carbohydrate(UC). The value of TDF was higher than the values of ADF, NDF and CF and lower than CDF and the Southgate method. The value of NDF showed the lower values than the CDF, Southgate fiber and TDF. The recovery rate of the fiber in the feces was high in the TDF, ADF, NDF and CF, while CDF and Southgate fiber showed lower recovery rates. TDF, NDF, ADF, or CF can replace chromium in the digestibility test, while the CDF and Southgate fiber can not replace chrorniurn. The digestibility of TDF, NDF, ADF and CF in the chicken showed negative values or values close to zero depending on the types of feed but the digestibility of CDF and Southgate fiber showed relatively high positive values.

• Journal of radiological science and technology
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• v.41 no.2
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• pp.149-155
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• 2018

Quantitative analysis was performed to confirm that moire artifact was removed without loss of image when using grid suppression software in the diagnosis of micro lesions. we showed that grid suppression images can be morphologically different from original images as they are significantly lower than those of the optimized grid in the similarity analysis with reference images in mammographic phantom images. We were confirmed that images of microcalcification with smaller signal than noise were lost because the pixel values of all lesions increased significantly after the grid suppression, The change in contrast using the NORMI 13 X-ray test phantom was reduced to 30% of the reference image, This result was significantly lower than the 90% when using the optimized grid. In conclusion, the use of grid suppression software in clinical images should be carefully considered because of the possibility of misdiagnosis due to micro lesion loss and morphological changes.

• Journal of Chest Surgery
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• v.27 no.10
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• pp.833-837
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• 1994

Lung contusion due to blunt chest trauma is the most common lung injury and correlated with the clinical course and prognosis. Its diagnosis by CT[Computerized Tomogram] gives a more clear and understandable three dimensional view, by which we are able to measure the volume of the contused and entire lung. Other variables are arterial blood gas, number of rib fracture, presence of hemopneumothorax, sternal fracture and clavicle fracture, number of associated non-thoracic injuries, ventilator time and presence of pulmonary complication. Percentage[%] of lung contusion are expressed as mean $\pm$ standard deviation and data analysis was performed by means of multivariate repeated measures analysis of variance to detect significant differences in variables between positive thoracic injury group and negative group. The paired t-test was used. Differences of percentage of lung contusion between groups were assessed by one-way analysis of variance. Simple linear regression was used to perform correlation analysis in the number of rib fracture and ventilator time. A p value less than 0.05 was considered statistically significant. Pneumothorax and the number of associated other injuries affect the amount of lung contusion and pulmonary complication group has more contused lung volume. Arterial blood gas study shows no correlation with the amount of lung contusion statistically. The number of rib fracture correlated with the amount of lung contusion, which also correlated with ventilator time[r=0.56, p<0.05]. In conclusion, quantitative anlysis of lung contusion by CT predicts the clinical course and treatment such as ventilator care.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.62 no.1
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• pp.18-22
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• 2013

This paper describes the information for quantitative simulation of weakly ionized plasma. We must grasp the meaning of the plasma state condition to utilize engineering application and to understand materials of plasma state. Using quantitative simulations of weakly ionized plasma, we can analyze gas characteristic. In this paper, the electron transport characteristic in $CH_4$ has been analysed over the E/N range 0.1~300[Td], at the 300[$_{\circ}\;K$] by the two term approximation Boltzmann equation method and Monte Carlo Simulation. Boltzmann equation method has also been used to predict swarm parameter using the same cross sections as input. The behavior of electron has been calculated to give swarm parameter for the electron energy distribution function has been analysed in $CH_4$ at E/N=10, 100 for a case of the equilibrium region in the mean energy. A set of electron collision cross section has been assembled and used in Monte Carlo simulation to predict values of swarm parameters. The result of Boltzmann equation and Monte Carlo Simulation has been compared with experimental data by Ohmori, Lucas and Carter. The swarm parameter from the swarm study are expected to sever as a critical test of current theories of low energy scattering by atoms and molecules.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.6A
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• pp.589-599
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• 2004

Most models assume the complete debugging environments by requiring a complete software correction in quantitative evaluation of software reliability. But, in many case, new faults are involved in debugging works, for complete software correction is impossible. In this paper, software growth model is proposed about incomplete debugging environments by considering the possibility of new faults involvements, and software faults occurrence status are also mentioned about NHPP by considering software faults under software operation environments and native faults owing to the randomly involved faults in operation before test. While, effective quantitative measurements are derived in software reliability evaluation, applied results are suggested by using actual data, and fitnesswith existing models are also compared and analyzed.

• Korean Journal of Soil Science and Fertilizer
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• v.45 no.5
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• pp.798-804
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• 2012

Although siderophores are induced primarily in response to iron deficiency, soil and other ecological factors can affect on this process. This study was to evaluate the production of siderophores by different fungal species isolated from heavy metal contaminated and uncontaminated soils. More than thirty fungal strains were isolated from heavy metal contaminated and rhizosphere uncontaminated soils. Chrome azurol sulfonate (CAS) was used for both quantitative and qualitative evaluation of siderophores production. No significant correlations were observed between the tested variables such as ultraviolet (UV) irradiation method and CAS-agar plate and heavy metal concentration in both soils. The production of siderophores in rhizosphere fungi was higher than those isolated from the contaminated soil; however, the difference was not significant. The siderophore production (%) by fungi isolated from heavy metal contaminated soil using UV irradiation method was positively correlated with the qualitative values using CAS-plate method (P<0.05). Pearson correlation test indicated a positive correlation between the quantitative and qualitative methods of detection for fungi isolated from rhizosphere and also those isolated from heavy metal contaminated soil.

• Journal of Korean Society for Quality Management
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• v.44 no.2
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• pp.277-296
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• 2016

Purpose: Propose model to diagnose and assess National Defense Industry and quality management by investigating and analyzing established standard model. Methods: Research on established internal model including MB, EQA and JQA model and make standard index for quality index extraction and quantitative index to test objectively for internal state. Results: Extract advantage and disadvantage by performance of National Defense Industry level diagnose and build foundation for quality management policy and road map. Conclusion: Due to result of diagnostic assesment of quality management of national defense industry, dependability, SCQM and safety part shows vulnerability and require improvement and support.

• Speech Sciences
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• v.7 no.2
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• pp.19-35
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• 2000

Speech evaluation and treatment planning for the patients with articulation disorders have traditionally been based on perceptual judgement by speech pathologists. Recently, various computerized speech analysis systems have been developed and commonly used in clinical settings to obtain the objective and quantitative data and specific treatment strategies. 10 dysarthric children (6 neurogenic and 4 functional dysarthria) participated in this experiment. Speech evaluation of dysarthria was performed in two ways; first, the acoustic analysis by Visi-Pitch and a Computerized Speech Lab and second, the perceptual scoring of phonetic errors rates in 100 word test. The results of the initial evaluation served as primary guidlines for the indivisualized treatment planning of each patient's speech problems. After mean treatment period of 5 months, the follow-up data of both dysarthric groups showed increased maximum phonation time, increased alternative motion rate and decreased occurrence of articulatory deviation. The changes of acoustic data and therapeutic effects were more prominent in children with dysarthria due to neurologic causes than with functional dysarthria. Three cases including their pre- and post treatment data were illustrated in detail.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2004.11a
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• pp.210-218
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• 2004

Poly(ADP-ribose)polymerase-1 (PARP-1) is a nuclear enzyme involved in various physical functions related to genomic repair, and PARP inhibitors have therapeutic application in a variety of neurological diseases. Docking and the QSAR (quantitative structure-activity relationships) studies for 52 PARP-1 inhibitors were conducted using FlexX algorithm, comparative molecular field analysis (CoMFA), and hologram quantitative structure-activity relationship analysis (HQSAR). The resultant FlexX model showed a reasonable correlation (r$^{2}$ = 0.701) between predicted activity and observed activity. Partial least squares analysis produced statistically significant models with q$^{2}$ values of 0.795 (SDEP=0.690, r$^{2}$=0.940, s=0.367) and 0.796 (SDEP=0.678, r$^{2}$ = 0.919, s=0.427) for CoMFA and HQSAR, respectively. The models for the entire inhibitor set were validated by prediction test and scrambling in both QSAR methods. In this work, combination of docking, CoMFA with 3D descriptors and HQSAR based on molecular fragments provided an improved understanding in the interaction between the inhibitors and the PARP. This can be utilized for virtual screening to design novel PARP-1 inhibitors.