• 제목/요약/키워드: quantitative factor

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고속도로 교통안전시설물의 정성적 및 정량적 위험도분석 연구 (A Study of Qualitative and Quantitative Risk Assessment for Highway Safety Facilities)

  • 지동한;오영태;최현호
    • 한국건설관리학회논문집
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    • 제8권4호
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    • pp.99-109
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    • 2007
  • 교통시설물의 위험요소는 안전피해의 규모 및 종류 등 복잡한 제반요소에 영향을 받기 때문에 안전개념에 기초한 분석이 요구된다. 이를 위해 본 연구에서는 교통안전시설에 대한 정성적 및 정량적 위험도분석 방법을 제시하고 이를 가치평가에 도입할 수 있는 절차를 제안하였다. 또한 정량적 분석을 위해 교통사고 데이터 및 이를 분석한 EPDO(Equivalent Property Damage Only)를 이용하여 사고빈도와 피해정도 및 사고요인별로 Event Tree를 작성하여 제시하였으며 이를 이용하여 중앙분리대 비교 1안(140cm) 및 비교 2안(127cm)에 대한 위험지수를 산정하였다.

아민 및 니트로화합물에 대한 QSAR의 물리화학적 매개변수 및 독성과의 상관관계 (A Study on the Correlationship among QSAR Parameters and Toxicity Data of Amine- and Nitrocompounds)

  • 김재현;김애경
    • Environmental Analysis Health and Toxicology
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    • 제14권1_2호
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    • pp.45-54
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    • 1999
  • Quantitative strucrure-activity relationships between the toxicity (LD$\_$50/) and molecular properties of amine and nitro compounds were tested. The all 19 compounds showed low correlations below 0.500 to their LD$\_$50/ values. When amine or nitro compounds were taken separately, the correlation between the calculated chemphysico parameters and LD$\_$50/ were also poor (r$^2$=0.4911, 3967 repectively). The overall relationships among the QSAR parameters were investigated. Molecular weight shows a high correlation with total surface area (r$^2$=0.9287); 0.9090 for zero-order connectivity and second-order connectivity : 0.8784 for bioconcentration factor and second-order connectivity. When amine compounds were taken to perform the statistical treatment, the relationships between parameters were as follows: 0.8436 for volume-negentropy; 0.8925 for volume-bioconcentration factor; 0.9929 for zero-order connectivity-Kow; zero-order connectivity-bioconcentration factor; 0.9141 for zero-order connectivity-solubility; 0.9718 for solubility-bioconcentration factor; 0.9894 for solubility-bioconcentration factor and 0.9319 for Kow-bioconcentration factor. On the other hand, nitro compounds showed different relationships as follows: 0.8952 for volume-I/O character; 0.9520 for volume-total surface area: 0.9351 for volume-molecular weight; 0.9351 for volume-MW; 0.9961 for Kow-Koc; 0.8455 for Kow-bioconcentration factor; 0.8879 for Koc-bioconcentration factor; 0.9987 for MW-total surface area respectively.

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일개 국내산 의료용 N95 마스크의 밀착도 분석 (Fit Testing for Domestic N95 Medical Masks)

  • 서혜경;강병갑;권영일
    • 한국산업보건학회지
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    • 제30권2호
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    • pp.124-133
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    • 2020
  • Objectives: Mask fit is a crucial factor in preventing respiratory infections among healthcare workers. The current coronavirus(COVID-19) pandemic calls for the replacement of imported N95 medical masks with domestic N95 versions. In this study, we aimed to determine whether these masks provide proper protection. Methods: Thirty-five participants from three healthcare institutions donned four types of masks and Quantitative Fit Tests(Portacount, USA) were performed. The order of fit test for the four types of masks was randomized, and a three-minute washout period was applied between test times(2 min 29 sec) to reduce potential error stemming from physical exhaustion. Results: There were no significant differences in the Fit Factor for the four types of masks, and there were no gender differences. However, the Fit Factor significantly differed across the three healthcare institutions (p=0.007). With eight of the 35 participants passing, the pass rate with the criteria of 100 or higher was 21%. Conclusions: The mask used in this study was a new domestic N95 medical mask, and the participants were unfamiliar with how to wear it. They reported difficulties with mask fitting. In light of a previous finding that mask fit improved with frequently used masks, wearer preferred masks, or when masks that are regularly worn are used during fit training, the fact that participants were unfamiliar with the mask used in this study is a limitation that should not be overlooked.

Metabolic Signatures of Adrenal Steroids in Preeclamptic Serum and Placenta Using Weighting Factor-Dependent Acquisitions

  • Lee, Chaelin;Oh, Min-Jeong;Cho, Geum Joon;Byun, Dong Jun;Seo, Hong Seog;Choi, Man Ho
    • Mass Spectrometry Letters
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    • 제13권1호
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    • pp.11-19
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    • 2022
  • Although translational research is referred to clinical chemistry measures, correct weighting factors for linear and quadratic calibration curves with least-squares regression algorithm have not been carefully considered in bioanalytical assays yet. The objective of this study was to identify steroidogenic roles in preeclampsia and verify accuracy of quantitative results by comparing two different linear regression models with weighting factor of 1 and 1/x2. A liquid chromatography-mass spectrometry (LC-MS)-based adrenal steroid assay was conducted to reveal metabolic signatures of preeclampsia in both serum and placenta samples obtained 15 preeclamptic patients and 17 age-matched control pregnant women (33.9 ± 4.2 vs. 32.8 ± 5.6 yr, respectively) at 34~36 gestational weeks. Percent biases in the unweighted model (wi = 1) were inversely proportional to concentrations (-739.4 ~ 852.9%) while those of weighted regression (wi = 1/x2) were < 18% for all variables. The optimized LC-MS combined with the weighted linear regression resulted in significantly increased maternal serum levels of pregnenolone, 21-deoxycortisol, and tetrahydrocortisone (P < 0.05 for all) in preeclampsia. Serum metabolic ratio of (tetrahydrocortisol + allo-tetrahydrocortisol) / tetrahydrocortisone indicating 11β-hydroxysteroid dehydrogenase type 2 was decreased (P < 0.005) in patients. In placenta, local concentrations of androstenedione were changed while its metabolic ratio to 17α-hydroxyprogesterone responsible for 17,20-lyase activity was significantly decreased in patients (P = 0.002). The current bioanalytical LC-MS assay with corrected weighting factor of 1/x2 may provide reliable and accurate quantitative outcomes, suggesting altered steroidogenesis in preeclampsia patients at late gestational weeks in the third trimester.

혼합모드 변동하중하에서 레일강의 피로균열 진전거동 (Fatigue Crack Growth Behavior for Rail Steel under Mixed Mode Variable Amplitude Loading)

  • 손경주;서영범;김철수;김정규
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2003년도 춘계학술대회
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    • pp.261-266
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    • 2003
  • The growth behavior of the transverse crack, which was one of the most dangerous damages of rail defects, was investigated under mode I and mixed mode loading in rail steel. In the case of variable amplitude loading, the fatigue crack growth behavior was discussed using characteristic stress intensity factor ranges ${\Delta}_{rms}$. In addition, characteristic comparative stress intensity factor ranges ${\Delta}_{V,rms}$ was proposed to evaluate the quantitative effects of the variable amplitude under mixed mode loading. As a result, crack growth rate under variable amplitude loading was faster than that under constant amplitude loading.

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안면부 여과식 방진 마스크와 안경 동시 착용 시 상호 영향 (The Effects of Interrelationship after Wearing between Respirators and Glasses Simultaneously)

  • 어원석;신창섭
    • 한국안전학회지
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    • 제33권1호
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    • pp.47-53
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    • 2018
  • This study compares the interrelation of fit factor(FF) and visual acuity test by the order of wearing preference between Particulate filtering face piece respirators(PFFR) and glasses for 54 participants. Glasses fitting factors is Optical Center Height(OH), Vertex Distance(VD) and Pantoscopic Angle(PA) or Visual acuity. We measured those factors and expressed by the ratio of standard point and change point. Quantitative fit factor was measured by Portacount Pro+ 8038 and compared the result of preference of wearing order between respirators and glasses. Also, we selected to 6 exercises among 8 exercises OSHA QNFT (Quantitative Fit testing) protocol to measure the fit factors. The pass/ fail criterion of FF was set at 100. Visual acuity test chart is developed by Chunsuk Han was used, Descriptive statistics was performed. Descriptive statistics(SAS ver 9.2), it is used geometric means, Wilcoxon analysis, peason correlation(P=0.05) Fit factor was increased when the respirator was worn before wearing the glasses(p=0.000) and decreased for visual acuity(p=0.000) The negative correlation was showed between OH and Overall fit factor(r=-0.409, p=0.002). Among 54 participants, 11 participants(20.3%) were worn respirator before wearing glasses and 1 participant(1.9%) was worn glasses before wearing respirator. The overall fit test showed the higher level was investigated for the group of participants wearing respirator before wearing glasses in 6 exercises. Also, overall fit factor were increased when participants wore glasses prior to respirator(16.6) to respirator prior to glasses(36.6). Visual acuity were increased when participants wore respirator prior to glasses(93.8) to glasses prior to respirator(106.0). Finally, comparison result of overall fit factor and visual acuity were glasses first choice from mask first choice. The results showed that higher overall fit factor was investigate when the participants wore the respirator prior to glassess at all. The results implied that it is important to maintain the overall fit factor and visual acuity according to the consideration of OH for glasses fitting when worker wore respirator and glasses at the same time.

Absolute Radiometric Calibration for KOMPSAT-3 AEISS and Cross Calibration Using Landsat-8 OLI

  • Ahn, Hoyong;Shin, Dongyoon;Lee, Sungu;Choi, Chuluong
    • 한국측량학회지
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    • 제35권4호
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    • pp.291-302
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    • 2017
  • Radiometric calibration is a prerequisite to quantitative remote sensing, and its accuracy has a direct impact on the reliability and accuracy of the quantitative application of remotely sensed data. This paper presents absolute radiometric calibration of the KOMPSAT-3 (KOrea Multi Purpose SATellite-3) and cross calibration using the Landsat-8 OLI (Operational Land Imager). Absolute radiometric calibration was performed using a reflectance-based method. Correlations between TOA (Top Of Atmosphere) radiances and the spectral band responses of the KOMPSAT-3 sensors in Goheung, South Korea, were significant for multispectral bands. A cross calibration method based on the Landsat-8 OLI was also used to assess the two sensors using near simultaneous image pairs over the Libya-4 PICS (Pseudo Invariant Calibration Sites). The spectral profile of the target was obtained from EO-1 (Earth Observing-1) Hyperion data over the Libya-4 PICS to derive the SBAF (Spectral Band Adjustment Factor). The results revealed that the TOA radiance of the KOMPSAT-3 agree with Landsat-8 within 5.14% for all bands after applying the SBAF. The radiometric coefficient presented here appears to be a good standard for maintaining the optical quality of the KOMPSAT-3.

호흡기보호구의 Fit Test 방법과 규정에 관한 고찰 (A Review on Fit Test for Respirators and the Regulations)

  • 한돈희
    • 한국산업보건학회지
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    • 제6권1호
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    • pp.38-54
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    • 1996
  • Respirator fit testing is required before entering specific work environmentals to ensure that the respirator worn satisfies a minimum of fit and that the user knows when the respirator fits properly. The fit of a respirator can be determined by qualitative (QLFT) or quantitative fit test (QNFT). The QNFT, having been universally accepted more than the QLFT, provide an objective and numerical basis by measuring a fit factor (FF). Until a few years age, only one QNFT technigue was available and accepted by U.S. Occupational Safety and Health Administration (OSHA) regulations. In the 1980's and 1990's, several new and fundamentally different QNFT methods were developed. Two of the newer methods are commercially availale and are accepted by OSHA as suitable alternatives. In this articles, the principle of operation of each ONFT technique is explained and each technique's major advantages and disadvantages are pointed out. Emphasis is given to negative-pressure air-purifying respirators, as they are in most frequent use today. The requirements and recommendations for fit testing positive-pressure respirators are discussed as well. Finally, the presently available QNFT standards and regulations are summarized to assist the user in making fit testing decisions.

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공공임대주택의 근린생활시설 활성화 방안 연구 (Study on the Direction to Revitalize Commercial Facilities in the Public Rental Housing Complexes)

  • 한다혁;이민석
    • 한국주거학회논문집
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    • 제28권1호
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    • pp.9-17
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    • 2017
  • This study investigates and analyzes (1) the status of neighborhood commercial facilities, (2) the location of neighborhood commercial facilities and (3) the users' viewpoint of them for the purpose of establishing the revitalizing factors of neighborhood commercial facilities within permanent rental housing complexes. This study attempts to determine the factors that revitalize neighborhood commercial facilities through quantitative factor analysis based on the analysis of the basic status and purpose of neighborhood commercial facilities using the basic status of permanent rental housing complexes and the quantitative data on neighborhood commercial facilities within these complexes. A survey investigating the residents' perception of neighborhood commercial facilities was conducted to analyze the qualitative aspects neighborhood commercial facilities within permanent rental housing complexes. The factors affecting the revitalization of neighborhood commercial facilities were analyzed by quantifying the actual problems perceived by the users and the elements of their use patterns. From these analysis results, it was found that the factors are not independent from one another, but organically affect one another. It is expected that more meaningful data will be obtained if future studies conduct correlation analysis and weighted value analysis on each factor based on the findings of the present study.