• Journal of Pharmacopuncture
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• v.19 no.3
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• pp.259-263
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• 2016

Lung cancer has a high mortality rate and is often diagnosed at the metastatic stage. Gefitinib is a targeted molecular therapeutic drug used to treat patients with non-small-cell lung cancer (NSCLC). Korean herbal medicines may also have therapeutic efficacy against lung cancer, reduce the side effects associated with chemotherapy, and improve patient quality of life (QOL). This case report describes the effects of a Korean herbal medicine regimen combined with gefitinib in a patient with NSCLC and bone metastasis. The Korean herbal medicine regimen included woohwanggeosa-dan, hwanggibujeong-dan and geonchilgyebok-jeong. The computed tomography (CT) findings showed that following combination treatment, the size of the tumor was markedly decreased without serious adverse events. Moreover, the Eastern Cooperative Oncology Group (ECOG) performance status was improved and cancer-related pain was decreased. These results suggest that a combination of Korean herbal medicines and gefitinib may be an effective therapeutic option for patients with advanced NSCLC and bone metastasis. Further studies are needed to examine the mechanism and the clinical efficacy of Korean herbal medicines against NSCLC.

• Journal of muscle and joint health
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• v.19 no.2
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• pp.197-209
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• 2012

Purpose: This study was aimed to revise Personal Power of Health Care (PPHC) scale which was developed to measure the personal power and competence for health care. Methods: Research phases designed for this study were literature review, scale development, and discussion with experts and pre-test for content validity, and survey for construct validity and reliability. The scale was composed of 25 items with 7 dimensions and tested to 592 adults ranged from 20 to 59 aged living in S and W city. Results: From factor analysis, 7 dimensions were identified and named as follows: Health-perception, Health problem identifying and solving, Socio-economical involvement, Sociocultural relationship, Self-regulation, Spiritual wellbeing, and Health policy participation. The total explained variance was 54.69%. The reliability was .817 of Cronbach's alpha. The PCHC scale was significantly different from gender, religion, education level, monthly income, and presence of family disease, but not different from age and job. Also, there were significant correlations among Health Promotion Lifestyles Profile II, WHO QOL-BREF and self-efficacy. Conclusion: This PCHC scale is reliable and valid to measure personal competence of health care.

• Journal of Korean Biological Nursing Science
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• v.18 no.4
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• pp.239-246
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• 2016

Purpose: The purpose of this study was to investigate the effect of denture care skills education program on denture self-care, denture satisfaction and subjective oral status among the elderly. Methods: The research design for this study was a non-equivalent control group quasi-experimental design. Total 61 elderly who visited a seniors center, Seoul, Korea, participated in this study. Participants were 31 elderly for the experimental group and 30 elderly for the control group. The experimental group received a lesson in denture care skills education program which was developed by the researchers. Using a structural questionnaire, the elderly's perception about denture self-care, denture satisfaction and subjective oral status were measured before and after the intervention. Descriptive statistics, independent t-test, chi-square test, and ANCOVA test were performed using SPSS WIN 21.0. Results: The experimental group showed significantly higher scores in denture satisfaction(p<.001), QOL of oral health(<.001), concern for oral health(p=.005), subjective oral health status(p<.001), bad breath(p=.010), oral dryness(p<.001) and number of denture clearing(p<.001). Conclusion: The results suggest that the denture care skills education program for elderly at a senior center was effective. Further work is required to develop more effective denture care skills education programs and an oral health promotion program to improve the health status of the elderly.

• Journal of Digital Convergence
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• v.11 no.11
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• pp.643-650
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• 2013

This study was conducted to examine the effects of low-density exercise on physical and psychological function of the frail elderly. The research design was nonequivalent control group pretest-posttest design. Data were analyzed using descriptive statistics, x2-test, Mann-Whitney U test and Cronbach's ${\alpha}$ with SPSS/Win 17.0 program. There was a significant improvement in Lt. Grip strength(U=56.00, p<.000), Rt. Grip strength(U=40.00, p<.000), TUG(U=95.00, p<.022), Depression(U=94.00, p<.011) in the experimental group compared to the control group. The low-density exercise program showed the effects to improve the physical and psychological functions of the frail elderly. In recommendation, this exercise program could be utilized as a health promoting program for the frail elderly.

• Korean Journal of Psychosomatic Medicine
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• v.27 no.2
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• pp.90-100
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• 2019

Objectives : This study aimed to investigate the association between depression with atypical features and metabolic syndromes in Korean adults using the 2016 Korean National Health and Nutrition Examination Survey (KNHANES) data. Methods : We used the 2016 KNHANES data to enroll 277 participants with a score of 10 or higher on Patient Health Questionnaire-9. Depression with atypical features was diagnosed when at least two of the following criteria were met : 1) sleeping more than 10 hours a day ; 2) weight gain of more than 3 kg in a year ; and 3) fatigue/anergia. Depression was divided into two groups based on the presence/absence of atypical features. Physical and mental health, and risk of metabolic syndrome were compared between the groups. Results : Among the 277 participants, 91 had depression with atypical features. We identified significant differences in age, sex, income, and education between the two groups. After adjusting for these variables, depression with atypical features had lower EuroQol-5D index scores (p<0.001) and higher prevalence of metabolic syndromes (p=0.035) compared to the depression without atypical features. Depression with atypical features had higher odds ratio (OR) in association with metabolic syndromes after adjusting for confounding variables (OR=1.923 ; 95% confidence interval : 1.069-3.460). Conclusions : Depression with atypical features increases the risk of metabolic syndromes and lowers the quality of life.

• Journal of Korean Ophthalmic Optics Society
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• v.15 no.2
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• pp.169-174
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• 2010

Purpose: The purpose of this study is to evaluate the long-term stability of the improved symptoms and accommodative functions after completion of accommodative therapy. Methods: Seven children (mean age${\pm}$SD: $12{\pm}1.41$ years) who were successfully treated with a vision therapy program for either accommodative insufficiency or infacility were followed for 1 year. The visual symptoms of the subjects were measured by the College of Optometrists in Vision Development Quality of Life (COVD-QOL) checklist, and this was followed by measurement of the monocular and binocular accommodative facility with ${\pm}2.00$ D flipper lens. Results: The mean visual symptoms at the 1 year follow-up examination ($15.14{\pm}8.59$) showed a small increase, but there was no significant difference (p=0.446) from post-therapy ($11.86{\pm}7.22$). There was small regression in the monocular (left eye, $13.86{\pm}3.93cpm$) and binocular ($11.14{\pm}3.13cpm$) accommodative facility at the 1 year follow-up examination, but there were no significant different from the monocular ($15.86{\pm}4.14cpm$, p=0.147) and binocular ($13.21{\pm}3.76cpm$, p=0.066) accommodative facility measurements at post-therapy. Also, every subject met the normative values of ${\geq}7$ cpm for monocular accommodative facility and ${\geq}5$ cpm for binocular accommodative facility in the long-term. Conclusions: There was long-term maintenance of the improved visual symptoms and accommodative functions, and so it is clear that the positive therapeutic effects persist with accommodative therapy.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.5
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• pp.1115-1125
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• 2009

Purpose: The purpose of this study was to investigate the Safety-practice and Its Related Factors among Elementary students in rural area, to provide the basic data for prevention for safety accident occurrence in order to improve the QOL. Methods: The subjects of this study were 549 elementary students using self-report questionnaires. The collected data was analyzed using descriptive statistics, t-test, ANOVA, Scheffe's test, Pearson correlation coefficient and stepwise multiple regression with SPSS 12.0 Program. Results: The mean score for level of the safety awareness was 3.55(${\pm}.36$) and of the safety practice, 2.98(${\pm}.48$). The score of Safety-practice was statistically significant difference according to students' gender(p= .028) and students' grade(p= .004), the number of friends(p= .002), the level of school life adaptation(p= .000), recognized learning proficiency(p= .000), personality(p= .005), curiosity(p= .003), the level of demand for safety education(p= .000), the level of safety-education conducted by parents(p= .000), the level of safety-education conducted by teacher(p= .000). Stepwise multiple regression analysis for Safety-practice revealed that the most powerful predictor was level of Safety-awareness and self-esteem, the level of safety-education conducted by parents explained 28.8% of the variance. Conclusions: Therefore, it is necessary to develop safety practice promotion program in order to enhance the quality of life of elementary students. Future studies need to be pursued to find various variances.

• Journal of Korean Medicine Rehabilitation
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• v.26 no.2
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• pp.105-121
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• 2016

Objectives The purpose of this study was to compare the effects between the degree of herniated intervertebral lumbar disc (HIVD) at L4-5 level and improvement of low back pain treated by Korean Medicine therapy. Methods 567 patients who received inpatient treatment from May 2014 to December 2015 in the Daejeon-Jaseng of Korean Medicine Hospital were divided into 6 groups by the degree of HIVD at L4-5 level confirmed with a Lumbar spine magnetic resonance imaging. All patients received a combination of treatment including acupunture, chuna manual therapy, pharmacopunture, herbal medication. They were compared and analyzed on the basis of improvement between measuring Numeric Rating Scale (NRS), Oswestry Disability Index (ODI), EuroQol-5 Dimension Index (EQ5D Index) as they were hospitalized and as they were discharged. The statistically significance was evaluated by SPSS 23.0 for windows. Results After treatment, Normal stage on Intervertebral Lumbar Disc at L4-5 level group's Numeric Rating Scale (NRS), Oswestry Disability Index (ODI), EuroQol-5 Dimension Index (EQ5D Index) improvement was $1.30{\pm}1.62$, $4.52{\pm}11.82$ and $0.04{\pm}0.11$ respectively. Bulging group's improvement was $3.25{\pm}2.81$, $8.28{\pm}13.02$ and $0.09{\pm}0.17$ respectively. Spinal canal occupying ratio (SOR) less than 20 group's improvement was $2.15{\pm}1.92$, $11.79{\pm}17.81$ and $0.13{\pm}0.23$ respectively. SOR 20 to less than 40 stage group's improvement was $2.13{\pm}1.92$. $10.79{\pm}15.93$ and $0.10{\pm}0.26$ respectively. SOR 40 to less than 60 group's improvement was $2.16{\pm}2.24$, $9.80{\pm}16.62$ and $0.15{\pm}0.25$ respectively. Surgery group's improvement was $2.47{\pm}2.21$, $11.64{\pm}18.53$ and $0.15{\pm}0.27$ respectively (p<0.03). But there was no statistically significance between 6 group's improvement after treatment (p>0.05). Conclusions After inpatient treatment by Korean Medicine therapy, Most patient's pain, disability and Health Related Quality of Life was improved significantly. But there was no statistically correlation between the degree of HIVD at L4-5 level and improvement of low back pain. So We think that future research of higher quality and correct statistics shall be necessary.

• The Journal of Korean Obstetrics and Gynecology
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• v.32 no.4
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• pp.116-131
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• 2019

Objectives: The aim of this study was to observe the changes of women's postpartum symptoms, the quality of life and depression scale over the first six weeks after childbirth. Methods: Twenty seven mothers who received Korean medical treatment in the outpatient department treatment (from September 27th, 2017 to January 5th, 2018) were evaluated for Verbal numerical rating scale (VNRS), edema index, EuroQol Visual Analogue Scale (EQ-VAS), and Edinburgh Postnatal Depression Scale (EPDS). Results: There were 17 high risk participants (63.0%) and 10 normal participants (37.0%). The VNRS of edema is the highest in the first week, and the VNRS of joint pain is the highest from the second week to the sixth week in all patients. The Extra Cellular Water/Total Body Water (ECW/TBW) of high risk group significantly decreased from $0.403{\pm}0.011$ to $0.387{\pm}0.006$(p<0.05) in the first 2 weeks. The ECW/TBW of normal group significantly decreased from $0.393{\pm}0.070$ to $0.383{\pm}0.011$ (p<0.05) in the first 2 weeks. The EQ-VAS of high risk group increased from $64.12{\pm}13.941$ to $69.35{\pm}18.155$ (p<0.05) in the first 2 weeks. But this difference was not significant statistically (p=0.234). The EQ-VAS of normal group significantly increased from $62.50{\pm}21.763$ to $74.00{\pm}9.661$ (p<0.05) in the first 2 weeks. The difference of EPDS was not statistically significant between the first week and the sixth week in every participants. Conclusions: VNRS was the highest in edema in the first week, joint pain was the highest from the second week to six week. The edema index of high risk groups was higher than that of the normal group in the first week (p<0.05). The EQ-VAS of normal group significantly increased (p<0.05) in the first 2 weeks but high risk group didn't. In the EPDS, the ratio of nine or more points of high risk group was more than twice than normal group in the first 2 weeks.

• The Journal of Korean Obstetrics and Gynecology
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• v.19 no.2
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• pp.240-260
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• 2006

Purpose : The objective of this study is to serve guidelines for the investigation and management of uterine myomas with KM therapies. Methods : English-language articles from PubMed and Korean-language articles from the database of the journal of oriental gynecology were reviewed from 2000 to 2005, using the key words 'uterine myoma', 'uterine leiomyoma', 'fibroid', 'uterine artery embolization', 'endometrial ablation', 'myomectomy', and jagungguenjong(子宮筋腫)'. Results and Limits : The areas of clinical practices considered in formulating this guideline are assessment, KM therapies, medical treatments, myolysis, selective artery occlusion, endometrial ablation and surgical therapies including myomectomy and hysterectomy. Implementation of this guideline would optimize the decision-making process of women with uterine myomas and further investigation or therapy of their KM doctors. But we don't have abundant evidences of clinical trials of uterine myoma treated with KM therapy, though we treat or manage that with every-day clinical practices. Moreover cultural gaps between Korea and other western countries make many differences in the attitude to surgical therapies, especially hysterectomy. So it is very difficult to compare W therapies with other therapies. Moreover it is much difficult to estimate cost-effectiveness and benefit of those therapies in QOL. Conclusions : The majority of uterine myoma is asymptomatic and will not require any intervention or further investigation. But unmarried women who wish to marry and get pregnant want to find safe therapy for their asymptomatic uterine myomas. In that case, most of the patients prefer non-surgical therapy to surgical therapy. So KM herbal medicinal therapy is a good alternative method for those patients. For the symptomatic myomas, hysterectomy offers a definitive solution. However, it is not the best solution for women who wish to preserve their uterus. So KM therapy is a good alternative for them. But the predicted benefits of alternative therapies including KM therapy must be carefully weighed against the Possible risks of these therapies. To improve the quality of life of both women with asymptomatic and symptomatic myomas, selecting and treating patients should be done carefully. Moreover, the effect of KM therapy has to evaluated, comparing the possible situation without treatment and the benefit of constant treatment as a health-care system.