• Korean Journal of Breeding Science
• /
• v.50 no.4
• /
• pp.364-377
• /
• 2018

Hexaploid wheat (common wheat/bread wheat) is one of the most important cereal crops in the world and a model for research of an allopolyploid plant with a large, highly repetitive genome. In the heritability of agronomic traits, variation in gene presence/absence plays an important role. However, there have been relatively few studies on the variation in gene presence/absence in crop species, including common wheat. Recently, a reference genome sequence of common wheat has been fully annotated and published. In addition, advanced next-generation sequencing (NGS) technology provides high quality genome sequences with continually decreasing NGS prices, thereby dawning full-scale wheat functional genomic studies in other crops as well as common wheat, in spite of their large and complex genomes. In this review, we provide information about the available tools and methodologies for wheat functional genomics research supported by NGS technology. The use of the NGS and functional genomics technology is expected to be a powerful strategy to select elite lines for a number of germplasms.

• Journal of Environmental Impact Assessment
• /
• v.30 no.4
• /
• pp.187-202
• /
• 2021

This study examined the effectiveness of wind corridor construction by analyzing the thermal environment, cold air generation, ventilation, and geographical characteristics to improve urban thermal environment and establish the basis for specialized strategy in Changwon-si, Gyeongsangnam-do. Using spatial analysis and remote sensing techniques, surface temperature, land cover and land use, wind field, and slope were measured and through this, a wind corridor analysis model was constructed. As a result of the analysis as of 2020, Changwon-si generally has land cover characteristics that are advantageous for the generation of cold air, but the temperature in most urban areas is the highest, and the temperature in areas such as north Changwon area, Jinbukmyeon, Ung-dong, and Ungcheon-dong are relatively high. There was a typical trend of high average wind speed in mountain regions and low average wind speed in urban areas. Accordingly, the north Changwon area, the former Changwon downtown area, the Hogye-ri and Pyeongseong-ri areas, and the Changpo Bay area are derived as vulnerable areas to thermal environment, and various measures to reduce temperature and improve air quality that the inflow of cold air into the area considering the characteristics of each area and securing wind ventilation between the surrounding mountains, reservoirs, and park areas were proposed.

• The Korean Journal of Archival Studies
• /
• no.70
• /
• pp.85-117
• /
• 2021

The purpose of this study is to investigate and analyze the current status of unit tasks, unit task operation, and record management problems used by local governments, and to present improvement measures using text-based big data technology based on the implications derived from the process. Local governments are in a serious state of record management operation due to errors in preservation period due to misclassification of unit tasks, inability to identify types of overcommon and institutional affairs, errors in unit tasks, errors in name, referenceable standards, and tools. However, the number of unit tasks is about 720,000, which cannot be effectively controlled due to excessive quantities, and thus strict and controllable tools and standards are needed. In order to solve these problems, this study developed a system that applies text-based analysis tools such as corpus and tokenization technology during big data analysis, and applied them to the names and construction terms constituting the record management standard. These unit task operation support tools are expected to contribute significantly to record management tasks as they can support standard operability such as uniform preservation period, identification of delegated office records, control of duplicate and similar unit task creation, and common tasks. Therefore, if the big data analysis methodology can be linked to BRM and RMS in the future, it is expected that the quality of the record management standard work will increase.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.32 no.6
• /
• pp.434-445
• /
• 2020

In this study, the minimization of harbor oscillation using permeable breakwater was applied to the actual harbor and investigated an effect of minimization by computer simulation in order to take into account the water quality problems and measures of harbor oscillation by infragravity waves at the same time. The study site is Mukho harbor located at East coast of Korea that harbor oscillation has been occurred frequently. The infragravity waves obtained by analyzing the observed field data for five years focused on the distribution between wave periods of 40 s and 70 s and wave heights in less than 0.1 m was 94% of analyzing data. The target wave periods was 68.0 s. The most effective method of minimization of harbor oscillation by infragravity waves was to install a detached permeable breakwater with transmission coefficient of 0.3 on the outside harbor and replace some area of the vertical wall in the harbor with wave energy dissipating structure to achieve a reflectivity of 0.9 or less. The amplitude reduction rate of this method shown in 27.4%. And the effect of the difference in transmission coefficient of permeable breakwater on the reduction rate of the amplitude was not significant.

• Journal of the Korean Regional Science Association
• /
• v.36 no.4
• /
• pp.3-23
• /
• 2020

This study aims to conceptualize the settlement inclusivity for overcoming social exclusion and the decline in quality of life of older people and to examine its effects on their mental health. The concept of the settlement inclusivity for older people focuses on the immediate environment around the place where they live. We proposed two domains for the conceptual framework; social domain that provides opportunities for community cohesion; spatial domain that provides security of residential area and access to basic services within walking distance. The social domain was represented by participation and interdependence, while the spatial domain by security and accessibility in the settlement inclusivity. Zero-inflated negative binomial regression model was constructed with 2017 National Survey of Older Koreans data to analyze the factors influencing depressive symptoms of older adults. The empirical results demonstrate that increased level of neighborhood network and social participation is associated with a decrease in the number of depressive symptoms. In addition, higher satisfaction in neighborhood environment and good accessibility to public transport/stores are associated with fewer depressive symptoms. Finally, housing condition and home ownership have a moderating effect on the relationship between social network/participation and depressive symptoms level, whereas they have no direct effects on depressive symptoms. This study demonstrates multi-dimensionally and mutually significant associations between settlement inclusivity and depressive symptoms for older people providing implications for urban planning and policies to improve mental well-being of older population.

• Journal of agricultural medicine and community health
• /
• v.45 no.4
• /
• pp.183-193
• /
• 2020

Objectives: As an ecological study, this study was performed to identify the community-level variation of health related quality-of-life (HRQOL), and to explore the factors that explain the variation, using 2017 Korean Community Health Survey (KCHS) data. Methods: Community health indicators of KCHS, which are correlated with the EQ-5D index of Si-gun-gu districts, were selected as independent variables. Multiple linear regression model was used to derive factors that explain regional variations in the EQ-5D index. Results: The EQ-5D index variation in 229 districts nationwide was 1.1 times for extremal quotient (EQ) and 1.0 for coefficient of variance (CV). The Si-gun-gu districts with the EQ-5D index in the lower 25% were more distributed in the province (27.7%) than in the metropolitan area (20.3%). As a result of multiple linear regression analysis, the depressed mood experience rate, perceived stress rate, suicide ideation rate, and physician diagnosed arthritis rate were derived as major factors of the variation. Conclusions: In order to reduce the gap in HRQOL between the districts, the priority of local health policies should be placed on the above factors including psychosocial factors.

• The Journal of Internal Korean Medicine
• /
• v.41 no.6
• /
• pp.1100-1118
• /
• 2020

Objectives: The purpose of this study was to assess the effects of acupuncture as a treatment for allergic rhinitis (AR). We used a meta-analysis and systematic review to analyze the results of randomized controlled trials (RCTs) that applied acupuncture to AR patients. Methods: The key question assessed the effects of acupuncture on patients with AR, and we included only RCTs. We searched the KoreaMed, NDSL, KMBASE, Koreantk, OASIS, PubMed, EMBASE, and Cochrane databases, with no language restriction. We assessed risk of bias with the Cochrane Risk of Bias tool. The random effects model was used to adjust for the heterogeneity of the included studies, and the effect sizes between two groups were reported as mean differences (MD) and risk ratios (RR). Results: Twelve RCTs were analyzed, with a total of 1788 participants; 824 participants were in the treatment group (i.e., acupuncture) and 964 were in the control group (sham acupuncture, western medicine, or waitlist). The meta-analysis results of 7 RCTs comparing the therapeutic efficacy of acupuncture with that of sham acupuncture showed a statistically significant difference (p<0.05) in the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) and the Change of Total Nasal Symptom Score (TNSS). The meta-analysis of 4 RCTs comparing the therapeutic efficacy of acupuncture with western medicine showed statistically significant differences (p<0.05) in the RQLQ but not in the changes in effective rate (p>0.05). Conclusions: Acupuncture can be an effective treatment for AR, but more studies are required to enhance the level of evidence and to confirm safety.

• Journal of Korean Medicine for Obesity Research
• /
• v.20 no.2
• /
• pp.178-192
• /
• 2020

Objectives: The present study aimed to compare the impacts of cognitive behavioral therapy (CBT) and behavioral treatment (BT) on weight loss and psychological outcomes among patients with three different subtypes of obesity: simple obesity, obesity with binge eating disorder, and obesity with depression. Methods: Embase, PubMed, the Cochrane Central Register of Controlled Trials, Research Information Sharing Service, and Korean Studies Information Service System were systematically searched for randomized controlled trials conducted on or before May 2020, that used CBT to treat obesity. Methodological quality was assessed using Cochrane's risk of bias tool 2 and publication bias was evaluated through the funnel plot using the trim and fill method, Egger's test, and Begg and Mazumdar rank correlation test. A meta-analysis was conducted using a random-effects model and the standardized mean difference with 95% confidence interval (CI) was used to determine effect size. Results: Twenty-one randomized controlled trials with a total of 22 intervention arms and 2,590 patients were included. Our study results revealed that the effects of CBT, compared with BT, on weight loss distinctly differed across all patient subgroups. In the simple obesity group, CBT was more effective than BT (Hedges' g=0.138, CI=0.012~0.264); however, in the obesity with binge eating disorder group, BT was more effective than CBT (Hedges' g=-0.228, CI=-0.418~-0.038); in the obesity with depression group, the effect of CBT was not statistically different from that of BT (Hedges' g=0.276, CI=-0.307~0.859). Further studies with larger sample sizes are required to confirm the outcomes observed in this study. Conclusions: Our results indicated that the effects of CBT on obesity treatment vary based on patient subtype. Therefore, our findings suggest that CBT or BT should be selectively recommended as a treatment strategy for different obesity subtypes.

• Journal of Korean Medicine for Obesity Research
• /
• v.20 no.2
• /
• pp.138-148
• /
• 2020

Objectives: The aim of this study is to evaluate the effects of Bangpungtongseong-san (Fangfengtongsheng-san, BTS) and Daesiho-tang (Dachaihu-tang, DST) on weight loss and improvement in lipid metabolism and glucose metabolism. Furthermore, we intend to develop a prediction model for drug effects through the analysis of the single nucleotide polymorphism (SNP), gut-microbiota, and the expression of immune-related biomarkers. Methods: This study is a single-center, randomized, double-blind, parallel-design clinical trial. One hundred twenty-eight participants will be assigned to the BTS group (n=64) and DST group (n=64). Both groups will be administered 4 g medication three times a day for up to 2 weeks. The primary outcomes is weight loss. The secondary outcomes include bioelectrical impedance analysis, waist circumstance, body mass index, total cholesterol, high-density lipoprotein, triglyceride, insulin resistance. The exploratory outcomes include 3-day dietary recall, food frequency questionnaire, quality of life questionnaire, gut microbiota analysis, immune biomarkers analysis, and SNP analysis. Assessment will be made at baseline and at week 4, 8, and 12. Conclusions: This protocol will be implemented by approval of the Institutional Review Board of Dongguk University. The results of this trial will provide a systematic evidence for the treatment of obesity and enable more precise herbal medicine prescriptions.

• The Journal of the Korea Contents Association
• /
• v.21 no.5
• /
• pp.94-104
• /
• 2021

It is no longer special for the gaming industry to provide a community to promote their games. Much prior research related to the community also focuses on the spread of community influence and its importance. In particular, the user community in the gaming industry is having a big impact on the company's revenue creation beyond the simple level of information provision and promotion of friendship. Therefore, providing a community at the same time as the game is released is becoming a common trend in the gaming industry This study attempted to explore factors influencing the design of more effective communities under the assumption that the user community will influence the loyalty of mobile games. The design elements of the community suggested in this study are the provision of interaction tools between users, the provision of information, and communication between the game maker and the users. This study aims to confirm that these design factors affect customer loyalty by reinforcing user empathy and trust in the game within the user community. After collecting data from 251 users active in the mobile game user community, the model presented in this study was empirically analyzed. As a result, the design elements of the game community suggested in this study were found to affect customer loyalty by strengthening the empathy for the game and the trust in the game developer.