• Journal of Haehwa Medicine
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• v.19 no.1
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• pp.35-48
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• 2010

In Neijing("內經"), it explains heaven, earth, four seasons(天地四時) take part in human's birth, it gives influence on life support, and have organic relationship between body and movement of sun and earth(日月運行) of heaven and earth. Human body and the natural world corresponds, so the time changes in the natural world give immediate influence to human body, and correspond changes happen inside human body. This has no exception in qi of human(人氣), meridians, the viscera and organs(臟腑) and so on. In time, there are many kinds of cycles such as year, month, 10 days and a day. Yin and yang and the five elements in each cycle shows changes of prosperity and decay and transformation. In a year, there are spring, summer, late summer, fall and winter which are each included to wood, fire, earth, metal and water. Spring and summer belong to yang(陽), and fall and winter belong to yin(陰). A day can be divided into the crowing of the cook, dawn, noon, and twilight. After midnight yin falls and yang rises(陰盡陽生), and after noon yang falls and yin rises(陽盡陰生). Ups and downs of the qi and blood and human body change with time and the region of whereabout is different. In one month, when the moon is full qi of blood rises and when the moon comes down qi of blood falls. The qi of meridian(經氣) has a periodical changes with regular movement in meridian. This is a result of continuing movement of meridian and the nutrient(營) and the defense(衛) in human body, stars correspond with ups, and correspond with flow of water of meridian(經水) with downs. In a day the twelve meridians(十二經脈) in hour of yin(hours 3~5), it starts with qi and blood of lung meridian(手太陰肺經) prosperous, each qi and blood of meridian prosperous in order. In eight extra meridians(奇經八脈), Bideungpalbup(飛騰八法) per 5 days, Younggoopalbup(靈龜八法) per 60 days qi of pulse(脈氣) changes correspond. The qi and blood of five meridian points(五兪穴) is 5 days, so.

• Proceedings of the KSME Conference
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• 2008.11a
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• pp.239-243
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• 2008

Nonferrous metals have a very important position in industry. At present, parts of shipbuilding, automobile, and aircraft etc. are designed and manufactured accurately, simultaneity need light-weight and high-strength. Aluminum copper alloys are one kind of typical precipitation hardening alloy which has been widely used. It is interesting to investigate transformation behavior of precipitated phase in such kind of alloys under high magnetic field. Transformation of materials under high magnetic field is many different compared with conventional condition. The author prepared the Al-4%Cu alloy.

• Journal of Haehwa Medicine
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• v.4 no.2
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• pp.337-353
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• 1996

The following results are obtained through study on the Three Eum and Three Yang. 1. Up to nowadays, many people confuse the Great Yang, the lesser Eum, the Great Eum, and the lesser Yang of the Sasang with the Great Yang, the lesser Yang, the Sunlight, the Great Eum, the lesser Eum, and the absolute Eum of the Three Eum and Three Yang becuase they are expressed with the same letters. But the former is the second specialization of the Eum and Yang, and the latter is the transformation of the six climate, so they cannot be the same thing, and there is no connection between them. 2. Three Eum and Three Yang is the outer expression of the six climate, which is coldness, heat, dryness, humidity, wind, and the fire, and it is the conception of the formation of objects which possess SI-JUNG-JONG & BON-JUNG-MAL, and it represents one term of the status of transformation in which the life and the Yang Qi are born, grown, united, and completed. 3. The Three Eum and Three Yang is not only applyed to the outer expression of the six climate, but also to the twelve channels which correspond with the twelve viscera, six differentiation of the disease of the cold, various illness, and the form of pulse. 4. The combination of the Three Eum and Three Yang and the twelve channels is divided into the channel of Sahwa and the channel of Jonghwa, and it also has important relationship with the physiology of the viscera. 5. The division of the six channels of disease of the cold suggested by Junggyung originates from the heat theory in Neagyung, but the six channels in the heat theory are of pathological conception, so the six channels of Junggyung includes the disease of the channels and the viscera. 6. The difference of the Pyo, Bon, Jung Qi of the Three Eum and Three Yang makes the syndrom of the disease diverse so it can be used in the diagnosis and the treatment of disease, and further studies are necessary on this part.

• Journal of Pharmacopuncture
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• v.10 no.3
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• pp.149-155
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• 2007

Objectives The purpose of this study is aimed at diagnosing and suggesting treatment plans for commonly seen clinical manifestation of heat symptom in the upper body and coldness in the lower body, also known as hot above, cold below syndrome. Methods Various reasons attribute to the presence of hot above, cold below syndrome, but mainly contributed by blockage of normal Qi flow by abnormality of heart-kidney root, spleen-stomach axis, and liver-lung axis. Diagnosing these abnormalities and timely alleviation to the healthy state is presented in the study. Results 1For heat in the upper body, Huang Lian Jie Du Tang(黃連解毒湯), CF, or JsD pharmacopuctures are injected on GB21, GB20. Qi stagnation in the thoracic area is treated with BUM injection on CV17. For impairment of transportation and transformation in the middle energizer, BUM pharmacopuncture is injected on CV12. Coldness in the lower energizer was relieved by bee venom or Sweet BV(Bee Venom free from enzymes) on CV6. Conclusion Above proposed methods of regulating water-fire were effective in treating hot above, cold below syndrome in clinical manifestations. But once the symptom subsides, treatment focused on eliminating innate cause should be rendered to achieve more successful results.

• Journal of Electrical Engineering and Technology
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• v.8 no.2
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• pp.271-281
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• 2013

In order to improve the performance of analysis, it is important to consider the nonlinearity in power system. The Carleman embedding technique (linearization procedure) provides an effective approach in reduction of nonlinear systems. In the approach, a group of differential equations in which the state variables are formed by the original state variables and the vector monomials one can build with products of positive integer powers of them, is constructed. In traditional Carleman linearization technique, the tensor matrix is truncated to form a square matrix, and then regular linear system theory is used to solve the truncated system directly. However, it is found that part of nonlinear information is neglected when truncating the Carleman model. This paper proposes a new approach to solve the problem, by combining the Poincar$\acute{e}$ transformation with the Carleman linearization. Case studies are presented to verify the proposed method. Modal analysis shows that, with traditional Carleman linearization, the calculated contribution factors are not symmetrical, while such problems are avoided in the improved approach.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.5
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• pp.2169-2177
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• 2014

Matrine, a main active component extracted from dry roots of Sophora flavecens, has been reported to exert antitumor effects on A549 human non-small lung cancer cells, but its mechanisms of action remain unclear. To determine effects of matrine on proliferation of A549 cells and assess possible mechanisms, MTT assays were employed to detect cytotoxicity, along with o flow cytometric analysis of DNA content of nuclei of cells following staining with propidium iodide to analyze cell cycle distribution. Western blotting was performed to determined expression levels of Bax, Bcl-2, VEGF and HDAC1, while a microarray was used to assessed changes of miRNA profiles. In the MTT assay, matrine suppressed growth of human lung cancer cell A549 in a dose- and timedependent manner at doses of 0.25-2.5 mg/ml for 24h, 48h or 72h. Matrine induced cell cycle arrest in G0/G1 phase and decreased the G2/M phase, while down-regulating the expression of Bcl2 protein, leading to a reduction in the Bcl-2/Bax ratio. In addition, matrine down regulated the expression level of VEGF and HDAC1 of A549 cells. Microarray analysis demonstrated that matrine altered the expression level of miRNAs compared with untreated control A549 cells. In conclusion, matrine could inhibit proliferation of A549 cells, providing useful information for understanding anticancer mechanisms.

• Journal of Oriental Neuropsychiatry
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• v.29 no.3
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• pp.183-195
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• 2018

Objectives: To investigate validity and effectiveness of Saam five element acupuncture treatment in psychological problems. Methods: We selected a Korean medicine doctor known to apply Saam five element acupuncture treatment to the psychiatry field. An investigator visited the doctor's clinic to observe the cases and interview patients. Duration of each interview was 30 minutes to one hour. A semi-structured questionnaire was used for in-depth interviews. All interviews were recorded and converted into texts. Converted texts were then summarized and analyzed qualitatively. Results and Discussion: Treatment process of Saam five element acupuncture designed for psychiatric use is divided into four stages: qi transformation (氣化), acupuncture treatment, deep breathing, and acupressure. In the first stage, patients are asked to express their feelings and emotions in a physical sense; to imagine their feelings have colors, weight, and physical form, and to describe those characteristics. Next, the doctor evaluates each patient's qi according to the six qi (六氣), and then determines protocol of Saam five element acupuncture treatment. This treatment is focused on suffering of the patient and specific symptoms or emotions. The treatment duration is brief and changes in symptoms are frequently checked during treatment sessions. Without discussing details of stressful events, the doctor enables patients to express physical aspects of their feelings. He also provides them with psychoeducational resources. As a result, patients experienced immediate changes in body sensation, emotions and thinking, decreased response to triggers, and increased self-control after treatment. Conclusions: The Saam five element acupuncture treatment has the potential to be used as a treatment for psychiatric disorders. Treatment can be effective in managing psychiatric disorders when applied by primary Korean medicine clinics.

• Journal of Korean Medical classics
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• v.32 no.4
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• pp.109-118
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• 2019

Objectives : In this study, the relationship between Tingling disease(痺證) and Accumulation (積) was examined focusing on the occurrence of Tingling disease and its development into tangible lesion. Methods : Based on related contents in the "Huangdineijing", the process of creation and development of Tingling and its transformation to Accumulation was mainly examined. Results : While Tingling disease is usually caused by the three Qis of Wind-Cold-Dampness, due to its Yin nature there is high tendency of Qi and blood to be blocked and Blood and Fluid-Humor agglomerating into Accumulation. Symptoms of dysaesthesia are merely expressions manifesting in this process. Development into colic accumulation [疝瘕], Gu(蠱), or convulsion[瘛] after Tingling has traveled to the five zang is also related to its transformation into Accumulation. In the case of Tingling disease of the five zang in the "Huangdineijing", it is not a diagnostic category for treatment but actual lesions in the five zang six fu. In other words, in the beginning stages of Tingling disease, some sort of solidification that causes abnormal senses among other symptoms happens, and this solidification starts taking up space within the flesh. If it is not eliminated and persists, it enters into the inner organs and develops Tingling disease of the zangfu. Conclusions : Understanding Tingling disease(痺證) as a presymptom to developing Accumulation, rather than abnormality of sense will enable people to have higher chances in treating tumor.

• Journal of The Association for Neo Medicine
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• v.1 no.2
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• pp.15-30
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• 1996

In the study about the logical basis and interpreting methods of animal experiments using rats in traditional medicine, several conclusions are obtained and summarized as following. 1. The logical basis of the animal experiments in traditional medicine is the essential homogeneity between human and rat defined as various transformation of one Qi(一氣) packed the cosmos. 2. Morphologically, the rat has abundant Yin(陰) and less Yang(陽) in most of anatomical characteristics. 3. Physiologically, the rat has unstable heart and mild temper with good fertility, which shows the features of Yin animal. 4. Pathologically, the rat shows the pathology of injury of viscera by stresses(氣激傷臟) and pathological transformations of internal water(痰飮水濕) mainly. 5. Constitutionally, the rat is alike to water type man(水形人) or Soeumin(小陰人) out of Yin Ren(陰人). 6. So, the rat is the proper experimental animal for diseases of sputum and water, emotional stimulations, endocrine system, heart, kidney, Yin syndrome(陰證) etc..

• The Korea Journal of Herbology
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• v.25 no.4
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• pp.151-160
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• 2010

Objectives : The purpose of this research was to examine dietary therapy on the edema based on the literary findings, for clinical treatment and prevention of the edema. Methods : This Research was examined on histories, compositions, applications, and effects of dietetic treatment about 100 cases of dietary therapy of the edema from Chinese literatures. Results : 1. Various vegetables and animals including herbs, grains, vegetables, fruits, food and drink were used for the dietary therapy. 2. Methods of the preparation for use as therapeutics were decoction, pulvis, gruel, cake, tea, paste, gelatin and etc. 3. Frequently used materials were Cyprinus carpio Linnaeus, Cucumis sativus L. Coix lachrymajobi var. mayuen, Zea mays, Maydis Stigma, Citrullus vulgaris, Zingiber officinale, Cinnamomum cassia Blume, Allium scorodorpasum var. viviparum Regel, Camellia sinensis, Armeniacae amarum Semen, Phyllostachys bambusoides, Luffa cylindrica, Dioscorea batatas Decne, Panax ginseng, Brassica oleracea and Raphanus sativus. Conclusion : Though dietary therapy for the edema is not based on clinical or experimental data, but through experience. It is mostly based on Yin-Yang and five elements, visceral manifestation, channels and their collateral channels and Oriental herbal medicine theories. If we use them properly according to oriental medicine method, it will be effective on treating and preventing the edema.