• Title/Summary/Keyword: purity assessment

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Preliminary Hazard Analysis for a Hyperbaric Oxygen Chamber (고압 산소 치료기에 대한 예비위험분석)

  • Jeon, Tae-Bo
    • Journal of Industrial Technology
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    • v.33 no.A
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    • pp.3-8
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    • 2013
  • Reduction of risk plays a pivotal role in the development of medical instruments. A hyperbaric oxygen chamber, as a medical device, is known to help medical therapy for diversity of diseases through provision of high purity oxygen. The use of hyperbaric oxygen is expected to increase in the future and study to rigorously examine reliability and safety is needed. We have performed risk assessment for a newly developed hyperbaric oxygen chamber in this study. We first briefly discussed the system structure and concept of risk assessment for the study. Based on the hazards identified, we performed preliminary hazard analysis for the chamber.

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Use of Microsatellite Markers to Identify Commercial Melon Cultivars and for Hybrid Seed Purity Testing (Microsatellite Marker를 이용한 멜론 시판품종의 품종식별과 F1 순도검정)

  • Kwon, Yong-Sham;Hong, Jee-Hwa
    • Horticultural Science & Technology
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    • v.32 no.4
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    • pp.525-534
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    • 2014
  • Microsatellite markers were used to identify 58 major commercial melon cultivars, and to assess hybrid seed purity of a melon breeding line known as '10H08'. A set of 412 microsatellite primer pairs were utilized for fingerprinting of the melon cultivars. Twenty-nine markers showed hyper-variability and could discriminate all cultivars on the basis of marker genotypes, representing the genetic variation within varietal groups. Cluster analysis based on Jaccard's distance coefficients using the UPGMA algorithm categorized 2 major groups, which were in accordance to morphological traits. The DNA bulks of female and male parents of breeding line '10H08' were tested with 29 primer pairs based on microsatellites to investigate purity testing of $F_1$ hybrid seeds, and 5 primer pairs exhibited polymorphism. One microsatellite primer pair (CMGAN12) produced unambiguous polymorphic bands among the parents. Among 192 seeds tested with CMGAN12, progeny possibly generated by self-pollination of the female parent were clearly distinguished from the hybrid progeny. These markers will be useful for fingerprinting melon cultivars and can help private seed companies to improve melon seed purity.

Assessment of a U Product purity from Pyroprocessing Spent EBR-II Fuel (EBR-II 사용후핵연료의 건식처리공정에 의한 우라늄의 순도 평가)

  • Lee, Jung-Won;Lee, Han-Soo;Kim, Eung-Ho;Lee, Jong-Hyeon;Vaden, D.;Westphal, B.;Simpson, M.F.
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.7 no.3
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    • pp.167-174
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    • 2009
  • A comprehensive analysis has been conducted on the purity of the uranium product generated from a pyroprocessing of EBR-II spent fuel. The analysis results were compared to the low-level waste criteria for both ROK and USA under a collaborative program between INL and KAERI. It is found that the US LLW definition does not include the activity from any U isotopes, but the Korean one does. The analysis results show that Pu-239 is the only alpha emitting isotope other than U isotopes that exceed the limit in the EBR-II U product. Pu contamination of the product seems to be drastically reduced in a preliminary test of the modified cathode process, and the further development of the proposed technology may be possible to meet the US LLW criteria.

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Assessment of Ni Catalyst Properties for Removal of O2 and CO Impurity in Inert Gas (불활성 가스의 O2와 CO 불순물 제거를 위한 Ni 촉매의 물성 평가)

  • Kim, Kwangbae;Jin, Saera;Kim, Eunseok;Lim, Yesol;Lee, Hyunjun;Kim, Seonghoon;Noh, Yunyoung;Song, Ohsung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.4
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    • pp.588-595
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    • 2020
  • This study examined the catalytic property of Ni-catalyst used in the gas purifying process to manufacture inert gases of N2 and Ar with high-purity over 9N for semiconductor industrial applications. Two types of Ni-catalysts with a cylindrical shape (C1) and churros shape structure (C2) were compared for the assessment. Optical microscopy and FESEM were used to analyze the shape and microstructure of the Ni-catalyst. EDS, XRD, and micro-Raman characterization were performed to examine the composition and properties. BET and Pulse Titration analyses were conducted to check the surface area and catalytic property of the Ni-catalyst. From the composition analysis results, C1 contained a relatively large amount of graphite as an impurity, and C2 contained higher Ni contents than C1. From specific surface area analysis, the specific surface area of C2 was approximately 1.69 times larger than that of C1. From catalytic property analysis, outstanding performance in O2 and CO impurity removal was observed at room temperature. Therefore, C2, having low-impurity and large specific surface area, is a suitable catalyst for the high-purity inert gas process in the semiconductor industry because of its outstanding performance in O2 and CO impurity removal at room temperature.

Radiolysis Assessment of $^{18}F$-FDG According to Automatic Synthesis Module (자동합성장치에 따른 $^{18}F$-FDG의 방사선분해 평가)

  • Kim, Si-Hwal;Kim, Dong-Il;Chi, Yong-Gi;Choi, Sung-Wook;Choi, Choon-Ki;Seok, Jae-Dong
    • The Korean Journal of Nuclear Medicine Technology
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    • v.16 no.1
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    • pp.8-11
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    • 2012
  • Purpose : Among quality control items, the radiochemical impurity must be below 10% of total radioactivity. In this regard, as the recently commercialized automatic synthesis module produces a large amount of 18F-FDG, radiolysis of radiopharmaceuticals is very likely to occur. Thus, this study compared the changes in radiochemical purity regarding radiolysis of $^{18}F$-FDG according to automatic synthesis module. Materials and methods : Cyclotron (PETtrace, GE Healthcare) was used to produce $^{18}F$ and automatic synthesis module (FASTlab, Tracerlab MX, GE Healthcare) was used to achieve synthesis into FDG. For radiochemical purity, Radio-TLC Scanner (AR 2000, Bioscan), GC (Gas Chromatograph, Agilent 7890A) was used to measure the content of ethanol included in $^{18}F$-FDG. Glass board applied with silica gel ($1{\times}10cm$) was used for stationary phase while a mixed liquid formed of acetonitrile and water (ratio 19:1) was used for mobile phase. High-concentration and low-concentration $^{18}F$-FDG were produced in each synthesis module and the radiochemical purity was measured every 2 hours. Results : The purity in low-concentration (below 2.59 GBq/mL) was measured as 99.26%, 98.69%, 98.25%, 98.09% in Tracerlab MX and as 99.09%, 97.83%, 96.89%, 96.62% in FASTlab according to 0, 2, 4, 6 hours changes, respectively. The purity in high-concentration (above 3.7 GBq/mL) was measured as 99.54%, 96.08%, 93.77%, 92.54% in Tracerlab MX and as 99.53%, 95.65%, 92.39%, 89.82% in FASTlab according to 0, 2, 4, 6 hours changes, respectively. Also, ethanol was not detected in GC of $^{18}F$-FDG produced in FASTlab, while 100~300 ppm ethanol was detected in Tracerlab MX. Conclusion : Whereas the change of radiochemical purity was only 3% in low-concentration $^{18}F$-FDG, the change was rapidly increased to 10% in high-concentration. Also, higher radiolysis were observed in $^{18}F$-FDG produced in FASTlab than Tracerlab MX. This is because ethanol is included in the synthesis stage of Tracerlab MX but not in the synthesis stage of FASTlab. Thus, radiolysis is influenced by radioactivity concentration than the inclusion of ethanol, which is the radioprotector. Therefore, after producing high-concentration $^{18}F$-FDG, the content must be diluted through saline to lower concentration.

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Failure Mode Analysis for a Hyperbaric Oxygen Chamber (고압산소 치료기에 대한 고장모드 분석)

  • Jeon, Tae-Bo;Park, Seong-Bin
    • Journal of Industrial Technology
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    • v.33 no.A
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    • pp.9-14
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    • 2013
  • Reliability plays a pivotal role in the development of medical instruments. A hyperbaric oxygen chamber, as a medical/health device, is known to help medical therapy for diversity of diseases through provision of high purity oxygen. The use of hyperbaric oxygen chamber is expected to increase in the future and study to examine reliability and safety is needed. We have performed reliability assessment for a newly developed hyperbaric oxygen chamber in this study. We first briefly discussed the system structure and mechanism. We then performed FMEA (Failure Mode and Effect Analysis) for the chamber. We drew major failure modes affecting the system performance and performed in depth analysis for measuring the expected effects.

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Estimating Chlorophyll-a Concentration using Spectral Mixture Analysis from RapidEye Imagery in Nak-dong River Basin (RapidEye영상과 선형분광혼합화소분석 기법을 이용한 낙동강 유역의 클로로필-a 농도 추정)

  • Lee, Hyuk;Nam, Gibeom;Kang, Taegu;Yoon, Seungjoon
    • Journal of Korean Society on Water Environment
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    • v.30 no.3
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    • pp.329-339
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    • 2014
  • This study aims to estimate chlorophyll-a concentration in rivers using multi-spectral RapidEye imagery and Spectral Mixture Analysis (SMA) and assess the applicability of SMA for multi-temporal imagery analysis. Comparison between images (acquired on Oct. and Nov., 2013) predicted and ground reference chlorophyll-a concentration showed significant performance statistically with determination coefficients of 0.49 and 0.51, respectively. Two band (Red-RE) model for the October and November 2013 RapidEye images showed low performance with coefficient of determinations ($R^2$) of 0.26 and 0.16, respectively. Also Three band (Red-RE-NIR) model showed different performance with $R^2$ of 0.016 and 0.304, respectively. SMA derived Chlorophyll-a concentrations showed relatively higher accuracy than band ratio models based values. SMA was the most appropriate method to calculate Chlorophyll-a concentration using images which were acquired on period of low Chlorophyll-a concentrations. The results of SMA for multi-temporal imagery showed low performance because of the spatio-temporal variation of each end members. This approach provides the potential of providing a cost effective method of monitoring river water quality and management using multi-spectral imagery. In addition, the calculated Chlorophyll-a concentrations using multi-spectral RapidEye imagery can be applied to water quality modeling, enhancing the predicting accuracy.

Assessment of Radiological Hazards in Some Foods Products Consumed by the Malian Population Using Gamma Spectrometry

  • Adama Coulibaly;David O. Kpeglo;Emmanuel O. Darko
    • Journal of Radiation Protection and Research
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    • v.48 no.2
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    • pp.84-89
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    • 2023
  • Background: Food consumption is one of the most important routes for radionuclide intake for the public; therefore, there is the need to have a comprehensive understanding of the amount of radioactivity in food products. Consumption of radionuclide-contaminated food could increase potential health risks associated with exposure to radiation such as cancers. The present study aims to determine radioactivity levels in some food products (milk, rice, sugar, and wheat flour) consumed in Mali and to evaluate the radiological effect on the public health from these radionuclides. Materials and Methods: The health impact due to ingestion of radionuclides from these foods was evaluated by the determination of activity concentration of radionuclides 238U, 232Th, 40K, and 137Cs using gamma spectrometry system with high-purity germanium detector and radiological hazards index in 16 samples collected in some markets, mall, and shops of Bamako-Mali. Results and Discussion: The average activity concentrations were 9.8±0.6 Bq/kg for 238U, 8.7±0.5 Bq/kg for 232Th, 162.9±7.9 Bq/kg for 40K, and 0.0035±0.0005 Bq/kg for 137Cs. The mean values of radiological hazard parameters such as annual committed effective dose, internal hazard index, and risk assessment from this work were within the dose criteria limits given by international organizations (International Commission on Radiological Protection and United Nations Scientific Committee on the Effects of Atomic Radiation) and national standards. Conclusion: The results show low public exposure to radioactivity and associated radiological impact on public health. Nevertheless, this study stipulates vital data for future research and regulatory authorities in Mali.

Water Quality Forecasting of River using Neural Network and Fuzzy Algorithm (신경망과 퍼지 알고리즘을 이용한 하천 수질예측)

  • Rhee, Kyoung-Hoon;Kang, Il-Hwan;Moon, Byoung-Seok;Park, Jin-Geum
    • Journal of Environmental Impact Assessment
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    • v.14 no.2
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    • pp.55-62
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    • 2005
  • This study applied the Neural Network and Fuzzy theory to show water-purity control and preventive measure in water quality forecasting of the future river. This study picked out NAJU and HAMPYUNG as the subject of investigation and used monthly the water quality and the outflow data of KWANGJU2, NAJU, YOUNGSANNPO and HAMPYUNG from 1995 to 1999 to forecast BOD, COD, T-N, T-P water density. The datum from 1995 to 1999 are used for study and that of 2000 are used for verification. To develop model of water quality forecasting, firstly, this research formed Neural Network model and divided Neural Network model into two case - the case of considering lag and not considering. And this study selected optimal Neural Network model through changing the number of hidden layer based on input layer(n) from n to 3n. Through forecasting result, the case without considering lag showed more precise simulated result. Accordingly, this study intended to compare, analyse that Fuzzy model using the method without considering lag with Neural Network model. As a result, this study found that the model without considering lag in Neural Network Network shows the most excellent outcome. Thus this study examined a forecasting accuracy, analyzed result and verified propriety through appling the method of water quality forecasting using Neural Network and Fuzzy Algorithms to the actual case.

Analysis of radioactivity levels and hazard assessment of black sand samples from Rashid area, Egypt

  • Abdel-Rahman, Mohamed A.E.;El-Mongy, Sayed A.
    • Nuclear Engineering and Technology
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    • v.49 no.8
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    • pp.1752-1757
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    • 2017
  • The aim of this study is to evaluate the radioactivity levels and radiological impacts of representative black sand samples collected from different locations in the Rashid area, Egypt. These samples were prepared and then analyzed using the high-resolution gamma ray spectroscopy technique with a high-purity germanium detector. The activity concentration ($A_c$), minimum detectable activity, absorbed gamma dose rate, external hazard index ($H_{ex}$), annual effective dose rate equivalent, radium equivalent, as well as external and internal hazard index ($H_{ex}$ and $H_{in}$, respectively) were estimated based on the measured radionuclide concentration of the $^{238}U$($^{226}Ra$) and $^{232}Th$ decay chains and $^{40}K$. The activity concentrations of the $^{238}U$, $^{232}Th$ decay series and $^{40}K$ of these samples varied from $45.11{\pm}3.1Bq/kg$ to $252.38{\pm}34.3Bq/kg$, from $64.65{\pm}6.1Bq/kg$ to $579.84{\pm}53.1Bq/kg$, and from $403.36{\pm}20.8Bq/kg$ to $527.47{\pm}23.1Bq/kg$, respectively. The activity concentration of $^{232}Th$ in Sample 1 has the highest value compared to the other samples; this value is also higher than the worldwide mean range as reported by UNSCEAR 2000. The total absorbed gamma dose rate and the annual effective dose for these samples were found to vary from 81.19 nGy/h to 497.81 nGy/h and from $99.86{\mu}Sv/y$ to $612.31{\mu}Sv/y$, which are higher than the world average values of 59 nGy/h and $70{\mu}Sv/y$, respectively. The $H_{ex}$ values were also calculated to be 3.02, 0.47, 0.63, 0.87, 0.87, 0.51 and 0.91. It was found that the calculated value of $H_{ex}$ for Sample 1 is significantly higher than the international acceptable limit of <1. The results are tabulated, depicted, and discussed within national and international frameworks, levels, and approaches.