• Parasites, Hosts and Diseases
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• v.23 no.2
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• pp.214-220
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• 1985

Four cases of human infection by Echinochasmus japonicus (Trematoda; Echinostomatidae) were proven by the recovery of adult worms after a treatment with praziquantel (10mg/kg in single dose) and purgation in February 1984 in Korea. The patients were 3 middle-aged men and 1 elderly woman residing in a riverside village of Kangjin-gun (Tamjin river), Jeonranam-do, an ever-known endemic area of metagonimiasis. The treatment revealed numerous M. yokogawai worms together with 1-43 (total 54) specimens of E. japonicus and/or a few number of other kinds of trematodes or cestodes. The patients had gastrointestinal troubles such as indigestion and abdominal discomfort, probably due to these fluke infections. They have been eating some raw flesh of fresh water fishes such as cyprinoid ones or sweet fish caught from the river. This is the first record of human E. japonicus infection in the literature.

• The Journal of Korean Medicine
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• v.19 no.2
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• pp.59-74
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• 1998

Clinical observation was done on 272 cases of patients who were diagnosed as CVA with brain CT, TCD, MRI scan and clinical observation. They were hospitalized in the oriental medical hospital of Kyung-Won University from 1st January to 31st December in 1997. 1. The cases were classified into the following kinds: cerebral infarction, cerebral hemorrhage. and transient ischemic attack. The most case of them was the cerebral infarction. 2. There is no significant difference in the frequency of strokes in male and female. And the frequency of strokes was highest in the aged over 50. 3. In cerebral infarction the most frequent lesion was the territory of middle cerebral artery, and in cerebral hemorrhage the most frequent lesion was the basal ganglia. 4. The most ordinary preceding disease was hypertension. and the next was diabetes. 5. The rate of recurrence was high in cerebral infarction. 6. The cerebral infarction occurred usually in resting and sleeping, and the cerebral hemorrhage in acting. 7. The common symptoms were motor disability and verbal disturbance. 8 The average time to start physical therapy was 1l.3rd day after stroke in cerebral infarction and it was 15.2th day after stroke in cerebral hemorrhage. 9. The common complications were urinary tract infection, pneumonia, myocardial infarction. 10. Hypercholesterolemia and hypertriglyceridemia are usually found more frequently in cerebral infarction than in hemorrhage. 11. In acute or subacute stage, the methods of smoothening the flow of ki(順氣), dispelling phlegm(祛痰), clearing away heat(淸熱) or purgation(瀉下) were frequently used. and in recovering stage, the methods of replenishing ki(補氣), tonifying the blood(補血) or tranquilization(安神) were frequently used.

• The Journal of Pediatrics of Korean Medicine
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• v.13 no.1
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• pp.63-138
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• 1999

From all possible chinese medical literatures, I studied the history of chinese pediatrics by dividing into Chunqiu Zhanguo, QinHan dynasties, LiangJin, SuiTang five dynasties, Song Dynasty, Jin and Yuan dynasties, Ming Qing dynasties. The conclusions are summarized as followings 1. The mentions related with pediatrics existed already in Yan ruins turtle shell letters, and 〈Yellow Emperor's classic of internal medicine> in Chunqiu Zhanguo time formed the system of medicine, established the theoretical foundation. 2. Chang Ji established the system of diagnosis and treatment based on overall analysis of symptoms and signs in , and later pediatricians commonly applied his prescriptions to the febrile diseases. 3. The period from LiangJin to SuiTang, Pediatrics was established as special department then in , Chao Yuanfang stated the etiology, pathogenesis, symptomatology of pediatric diseases. 4. In Song dynasty. pediatric 4 major, symptoms that had been mentioned from SuiTang dynasties, were clearly established, pediatrical special books were published, and written by Qian Yi who is considered as the founder of chinese pediatrics, established the foundation of pediatrical division formation in distinction from adult fields. 5. In Jin and Yuan dynasties, four eminent physicians established the actual relationship between the theories and practical applications and insisted various and creative theories based on the classical medicine, for example, the theory that fire and heat in the body was the main cause of diseases of Liu Wansu purgation theory of Zhang Congzheng, qi regulating theory of Liu Gao, ministerial fire theory and the theory that yang is ever in excess while Yin is ever deficient of Zhu Zhenheng, etc, and they applied those theories to pediatrical various sides. 6, In Ming Qing dynasties, pediatrical specialists and pediatrical publications had increased, eg, father and son Xue Kai Xue Ji, Wan Quan, Lu Bai-si, etc in Ming dynasty, Ye Gui, Chen Fuzheng, Xia Ding, etc in Qing dynasty were famous as pediatricians. Specially, the doctrine of epidemic febrile diseases at that time showed prominent effects to children's epidemic febrile diseases.

• Journal of Acupuncture Research
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• v.22 no.4
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• pp.131-141
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• 2005

Objectives : Saam acupuncture has evident principles of prescription based on acupuncture tonification and purgation of Nan-gyeong but many prescriptions of Saam acupuncture are not typical patterns. This paper studies principles of prescriptions of the king fire and the premier fire. Methods : Through investigation of many medical documents concerning king fire and the premier fire, the author explained of physiological and pathological principle of king and the premier fire, also explained of interacting mechanism through five element. And The theoretical authorities of analysis are Nan-gyeong, works of Joo dan-gye and Li dong-won. Results & Conclusion : 1. The sufficiency and the control of the water is the key to treat the disease by fire. Considering the attack and the treatment of disease, heart and liver give rise to fire in its early stage and kidney and lung are the key to treatment. 2. Consequently the pathology of the disease from fire is corresponding to the theory- Yang Sufficient, Yin Deficient- of Joo dan-gye. It seems that the theory of Joo dan-gye influenced on the medical theory of Saam Acupuncture. 3. On that account I believe that the study of medical theories of the Geum and Won Dynasty that various medical theories had appeared is very available for Saam Acupuncture. At present global warming is accelerating because environmental pollution has been increasing. Therefore the damage of fire to human body will be more and more severe and extensive. Because in the future medical plants will not be free from environmental pollution, acupuncture will be very confidential treatment.

• Journal of Pharmacopuncture
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• v.3 no.2
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• pp.1-25
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• 2000

We were trying to study the validity of Puffer fish's poison(Tetrodotoxin- TTX) to make a traditional Korean Medical treatment. The following conclusions were made after literary studies. 1. The first record of the puffer fish dates back 2000 years ago in the Chinese text Book of Mountain and Sea and other texts from the similar period. 2. Puffer fish's poison IS known as tetrodotoxin which is an amino perhydroquinazoline compound. It has a chemical formula of $C_{11}H_{17}N_3O_8$ in the hemiacetal structure and has the molecular weight of 319. 3. Tetrodotoxin (TTX) plays a role as potent neurotransmitter blocker by blocking the $Na^+$ -gate channel which hinders the influx of $Na^+$ ion into the cell. 4. Symptoms of the puffer fish poisoning ranges from blunted sense in the lips and tongue, occasional vomiting in the first degree to sudden descending of the blood pressure, apnea, and other critical conditions in the fourth degree. Intoxication of the puffer fish poison progresses at a rapid pace as death may occur after an hour and half up to eight hours in maximum. Typical death occurs after four to six hours. 5. Ways to treat the puffer fish poisoning include gastric irrigation, induce vomiting, purgation, intravenous fluid injection, and correcting electrolytic imbalance and acidosis. In cases of dyspnea, apply oxygen inhalation and conduct artificial respiration. 6. Tetrodotoxin (TTX) may be applied in treating brain disorders, ocular pain, excess pain in the large intestine and ileum, and relieving tension of the skeletal museles, neuralgia, rheumatism, arthritis, and etc. 7. In terms of Oriental medicine, the puffer fish poison has characteristics of sweet, warm, and poisonous. It's known efficacies are to tonify weakness, dispel damp, benefit the lower back, relieve hemorrhoid, kills parasites, remove edema, and so forth. And the puffer fish eggs processed with ginger are said to be effective against tuberculosis and lung cancer, thus, it's validity must be investigated and further research should be followed.

• The Journal of Internal Korean Medicine
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• v.12 no.1
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• pp.155-165
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• 1991

On the treatment of C.V.A, I obtain the results through the bibliographic investigation in the method of Chong-Yol-Sa-Hwa as follows ; 1. The method of Chong-Yol-Sa-Hwa on the treatment of CVA. is used for the occation of flaming fire in the heart caused by fire emotions in excess (五志過極), difficiency of Yin, flaming up of excessive in liver and plegm-heat. 2. The representative symptoms which can be used by the method of Chong-Yol-Sa-Hwa are firerishness, redness on face, foul breath, fidgets, angry, high fever, constipation slimy and greasy yellow coat of the tongue, and the pulse shaped on full-rapid (洪數), tautsmaooth and rapid (弦滑血數). 3. The general prescription on the method of Chong-Yol-Sa-Hwa are Bang pung tong sung-San, Yangkyuk-San, Backho-Tang, Sosiho-Tang, Samhwa-Tang, Chibo-Tan and Woohwang chongsim-Hwan on excessive symptom-complex, Yookmichihwang-Tang-Kakam, Samool-Tang-Kakam and Youngyangkak-Tang on insufficency symptom complex. 4. The most frequently dosed medicinal plants are Seok-ko, Chi-mo, Dae-Hwang, Mang-cho, Hwang-kewm, Hwang-back, Chi-ja, Si-ho, Han-Su-Seok, Yong-Tam-Cho, Mok-Tan-Pi and Saeng-Chi-Hwang. 5. The method of chong-Yol-Sa-Hwa might be expressed good medicinal effects adopted on the symptoms or flaming evil fire (火旺) after awakend and ‘Yang’ occlusion of Chung-Chang-Pu (中臟脈) which is accompanied with the method of purgation, break through the plegm, resuscitate and nourishing the Yin.

• Parasites, Hosts and Diseases
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• v.32 no.3
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• pp.149-156
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• 1994

An epidemiological study fur the Intestinal trematode infection of the villagers was done In Koje-myon, Kochang-gun, Kyongsangnam-do, Korea in March, 1994. Of 116 stool specimens examined, total helmlnthic ova positive cases were 13 (11.2%) and cumulative ova positive cases 21 (18.1%): Echinostoma hortense 11 cases (9.5%), Metngonimus sp. 6 cases (5.2%), and Clonorchis sinensis 4 cases (3.4%). After the treatment and purgation, variable numbers of E. hokene, 6 to 227 per person, were collected from 7 echlnostome egg Positive cases, together with M. tokohoshii In 6 cases. Three adult flukes of E. cinetorchis were collected from one person and one Stellantchasmw jnlcatus was recovered from another case. This mountainous village was proved to be one of the endemic foci of echlnostomlasis In Korea.

• Parasites, Hosts and Diseases
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• v.45 no.2 s.142
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• pp.149-152
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• 2007

A cohort was established for evaluation of cancer risk factors in Sancheong-gun, Gyeongsangnam-do, Korea. As one of the cohort studies, stools of 947 residents (403 males and 544 females, age range: 29-86 years) were screened for Clonorchis sinensis eggs using both Kato-Katz method and formalin-ether sedimentation technique. The overall egg positive rate of C. sinensis was 37.7% and individual EPG (eggs per gram of feces) counts ranged from 24 to 28,800. Eight egg positive residents voluntarily joined a process of collection of the passed worms after praziquantel treatment. A total of 158 worms were recovered from 5 of the 8 treated persons, ranged from 3 to 108 in each individual. The worms were $15-20 mm{\times}2-3 mm$ in size, and showed brown-pigmented, red, or white body colors. This is the first collection record of C. sinensis adult worms from humans through anthelmintic treatment and purgation. The adult worms of C. sinensis may be paralyzed by praziquantel and then discharged passively through bile flow in the bile duct and by peristaltic movement of the bowel.

• Journal of Korean Medical classics
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• v.21 no.1
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• pp.13-26
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• 2008

Pediatrics in Geumwon(金元) age had fanned peculiar children's etiology, Byeonggihak(病機學) and Byeonjeungnon(辦證論) curative system grounded on medical theory in Geumwonsadaega(金元四大家). Yuwanso(劉完素), who was front-running man in that age, used so many times 'Yanggyeoksan(凉隔散)' or 'Bangpungtongseongsan(防風通聖散)' which have Hanryang(寒凉) disposition for curing children's disease in view of pathology in Yeoldahanso(熱多寒少), which is his special academic thought, after then Judangye(朱丹溪) succeed Yuwanso(劉完素)'s this view of pathology, Yang-eumjahyeol(養陰滋血) developed the one and made it a standing rule to cure children. Also Idongwon(李東垣) grasped that the main cause of disease is starvation because of war. As a result of it, he insisted on theory, internal cause's outbreak of person's illness, Naesangbiwi(內傷脾胃), Baekbyeong-yusaeng(百病由牛). In this view of this principle, he assorted and used following medicine 'Seungma(升麻), Siho(柴胡), Hwanggi' as 'Seungbalyanggi(升發陽氣)' method to cure children, and concentrated on children's spleen and stomach cure with this way. Jangjongjeong(張從政) applied 'Purgation therapy[攻下法]', Hantoha(汗吐下) centered on the theory of exogenous factors[外因說] , which explains that children's disease is Sagichimseup(邪氣侵襲), too. Like this, in Geumwon(金元) age, they had studied very seriously about main cause of children' s disease in two part, an internal cause and an external cause. Also, in pathological part they had approached academically 'Hwayeolchibyeong(火熱致病)' and 'Gigiseunggangsiljo(氣機乘降失調)' from diverse angles.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.5
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• pp.1341-1345
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• 2007

There are four kinds of formulas for purging the liver to cure its sthenic syndrome based on the types of preparation formulas : Sagan-tang, Saganhwan, Saseem-san and Saganeum. Another formula called Sacheonghwan, Sacheong-tang and Sacheong-san is to purge the green colour of liver. There are 38 kinds of Sagan-tang, 2 kinds of Saganhwan, 29 kinds of Sagan-san, 5 kinds of Saganeum, 4 kinds of Sacheonghwan, 3 kinds of Sacheong-tang and 1 kind of Sacheong-san. Combination of herbal medicines, carried out in formulas for purging the liver, consists of various kinds depending on medical scientists' personal experience in medical treatment without any general principles, which makes it difficult to apply it to clinical use. The objectives of this study lie in theoretical establishment of Sagan-tang for curing the sthenic syndrome of liver through analyzing the component medicines and combination principles of Hyeongok's Sagan-tang, and furthermore, maximizing the clinical use of Sagan-tang. This study analyzed the component medicines and combination principles of Hyeongok's Sagan-tang based on the theory for properties and tastes of herbal medicines from the ${\ulcorner}$Yellow Emperor's Canon of Internal Medicine${\lrcorner}$, the theory for principal herbal medicine, assistant herbal medicine, adjuvant herbal medicine, dispatcher herbal medicine, and the five elements doctrine. Hyeongok's Sagan-tang is an odd prescription, composed of 7 kinds of ingredients : No.1 Radix Paeoniae (2don;7.5 g), No.2 Fructus Chaenomelis (1don;3.75 g), No.3 Radix Rehmanniae (1don), No.4 Folium Phyllostachydis Henonis (1don), No.5 Radix Bupleuri (1don), No.6 Radix Scutellariae (1don), and No.7 Radix Glycyrrhizae (1don). There are three methods for curing the sthenic syndrome of liver according to the five elements doctrine : purging the liver, purging the heart and invigorating the lung. In the case of taste purgation, two herbal medicines with sour taste, Radix Paeoniae and Fructus Chaenomelis, are combined into the principal and assistant herbal medicine, respectively. For property purgation, two herbal medicines with the cool property, Radix Bupleuri and Radix Scutellariae, are combined into adjuvant herbal medicines. Both sweet and cold herbal medicines, Radix Rehmanniae and Folium Phyllostachydis Henonis, are combined into adjuvant herbal medicines. Sour herbal medicines, Radix Paeoniae and Fructus Chaenomelis, were combined to invigorate the lung. Cool herbal medicines, Radix Bupleuri and Radix Scutellariae, were combined to invigorate the lung and to purge the liver. In addition, Radix Glycyrrhizae are combined as dispatcher herbal medicine, harmonizing all the herbal medicines composing the formula. First, to cure the sthenic syndrome of the liver, the methods of purging the liver and the heart, and invigorating the lung should be used according to the five elements doctrine. Secondly, herbal medicines appropriate for those treatment methods should be chosen according to the theory for properties and tastes of herbal medicine and thirdly, the combination of those herbal medicines should be carried out according to the theory for principal herbal medicine, assistant herbal medicine, adjuvant herbal medicine, dispatcher herbal medicine. As a good example, Hyeongok's Sagan-tang is combined according to the above theories.