• 대한기계학회논문집B
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• 제32권11호
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• pp.891-896
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• 2008

In the present computational study, simple stenotic artery models using pulsatile flow condition were investigated. A 1 Hz non-reversing sinusoidal velocity for pulsatile flow was imposed at the flow inlet and the corresponding Womersley number based on the vessel radius is 2.75. The simple stenotic geometries have been used that consist of 25%, 50% and 75% semicircular constriction in a cylindrical tube. In this paper, numerical solutions are presented for a first harmonic oscillatory flow using commercial software ADINA 8.4. As stenosis and Reynolds number increase, the maximum wall shear stress(WSS) increases while the minimum WSS decreases. As the stenotic rate increases, the pressure drop at the throat severely decreases to collapse the artery and plaque. It is found that the fluid mechanical disturbances due to the constriction were highly sensitive with rate of stenosis and Reynolds number. When Reynolds number and stenosis increase, the larger recirculation region exists. In this recirculation region the possibility of plaque attachment is increasingly higher. The present results enhance our understanding of the hemodynamics of a stenotic artery.

• 대한기계학회논문집B
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• 제27권7호
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• pp.920-928
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• 2003

The objective of the present study was to investigate the characteristics of flow and wall shear stress under steady and pulsatile flow in the aneurysm. The numerical simulation using the software were carried out for the diameter ratios ranging from 1.5 to 3.0, Reynolds number ranging from 900 to 1800 and Womersley number, 15.47. For steady flow, it was shown that a recirculating vortex occupied the entire bulge with its core located closer to the distal end of the bulge and the strength of vortex increased with increase of the Reynolds number and diameter ratio. The position of a maximum wall shear stress was the distal end of the aneurysm regardless of the Reynolds number and diameter ratios. For the pulsatile flow, a recirculating flow at the bulge was developed and disappeared for one period and the strength of vortex increased with the diameter ratio. The maximum values of the wall shear stress increased in proportion to the diameter ratio. However, the position of a maximum wall shear stress was the distal end of the aneurysm regardless of the diameter ratios.

• 대한기계학회논문집B
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• 제20권11호
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• pp.3607-3619
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• 1996

Experimental and numerical studies for three-dimensional pulsatile flows are conducted to investigate the flow characteristics in the bifurcated tubes. Velocity measurements in experimental study were made by both Pulsed Doppler Ultrasound(PDU) machine and Laser Doppler Anemometer(LDA) system. Glycerin is used for experimental study. Experimental results are used to verify the results of the numerical simulation. Flow characteristics of Newtonian fluid and blood in the bifurcated tubes under the steady and pulsatlie flows are numerically investigated. Finite volume method is employed for three-dimensional numerical simulations. Blood is considered as a non-Newtonian fluid and the constitutive equation of blood is used for the numerical analysis. Numerical analyses are focused on the flow patterns for various branch angles ranging from 30.deg. to 90.deg. and diameter ratios such as 1.0, 0.8, and 0.6. Pulsatile flow characteristics of blood are compared with those of Newtonian fluid. Parameter effects on axial velocity, pressure and wall shear stress distribution along the bifurcated tubes are discussed in terms of the branch angle, diameter ratio, and Reynolds number.

• 대한의용생체공학회:의공학회지
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• 제19권3호
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• pp.313-320
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• 1998

3상형 박동류는 인체 순환계 혈류의 일반적인 형태이다. 심혈관계의 여러 가지 상황을 모의하려면 이러한 3상형 박동류를 만들어 내는 것이 필수적이다. 본 연구에서는 3상형 박동류를 모의하기 위해서 전기유압식 좌심실보조기를 유리 팬텀과 고무 튜브와 같이 사용하였으며 혈류 모의 시스템의 제어변수를 선정하고 각 변수들의 변화에 대한 영향을 도플러 초음파를 이용하여 관찰하였다. 본 실험의 결과 협착 후위부 탄성과 지연시간이 3상형 혈류를 생성하는 중요한 요인이었다. 본 실험의 결과들은 다양한 혈류 운동을 모의할 수 있게 해 줌으로써 심혈관계의 여러현상을 설명하는 유용한 도구가 될 수 있을 것으로 기대된다.

• Journal of Advanced Marine Engineering and Technology
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• 제37권2호
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• pp.149-155
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• 2013

혈류 유동 연구를 위해서는 심장의 맥동 유동을 만들어 내는 것이 중요하다. 본 연구에서는 동맥혈류의 유동 해석을 위해 새롭게 설계된 심장 박동 모사 맥동펌프의 제작 및 그 성능에 관하여 시험을 수행하였다. 피스톤 펌프를 이용한 기본몸체 설계를 수행하였고 직류모터와 엔코더를 사용하여 회전수와 가속비를 설정할 수 있도록 하였으며, 시험결과는 전 영역에서 맥동 유동의 분포를 잘 따르고, 반복되는 맥동 주기의 편차도 작게 나타남을 확인하였다.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2008년도 춘계학술대회논문집
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• pp.6-9
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• 2008

Analyzing the characteristics of blood flow in the blood vessels is very important to diagnose the circulatory diseases. In order to investigate the hemodynamic characteristics in vivo, the measurements of blood flows inside the extraembryonic arterial and venous blood vessels of chicken embryos were carried out using an in vivo micro-PIV technique. The circulatory diseases are closely related with the formation of abnormal hemodynamic shear stress regions, thereby it is important to get blood velocity and vessel's morphological information according to the vessel configuration and the flow conditions. In this study, the flow images of RBCs in blood vessels were obtained using a high-speed CMOS camera with a spatial resolution of approximately 14.6${\mu}$m${\times}$14.6${\mu}$m in the whole circulation network of blood vessels. The blood flows in the veins and arteries show steady laminar and unsteady pulsatile flow characteristics, respectively. The mean blood flows merged (in veins) and bifurcated (in arteries) smoothly into the main blood vessel and branches, respectively, without any flow separation or secondary flow which accompanying large variation of shear stress. Vorticity was high in the inner regions for both types of vessels, where the radius of curvature varied greatly. The instantaneous flows in the arterial blood vessels showed noticeable pulsatility due to the heart beat, and the main features of the velocity waveforms, including pulsatile shape, retrograde flow, mean velocity, maximum velocity and pulsatile frequency, were significantly dependent on the pulsatile condition which dominates the arterial blood flow. In near future, these in vivo experimental results of blood flow measured in various extraembryonic blood vessels would be very useful to understand the hemodynamic characteristics of human blood flows and various blood flow researches for clinically useful hemodynamic discoveries as well.

• 대한의용생체공학회:의공학회지
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• 제29권5호
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• pp.376-383
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• 2008

High-flux dialysis treatment removes various toxins via diffusion as well as convection, which is induced by ultrafiltration and backfiltration. In this study, in vitro (Using the distilled water and the bovine's blood) comparison test was performed to determine whether utilization of a high flux dialyzer paired with different pumps would increase the efficiency of convection. At the same blood flow rates, a pulsatile pump and a roller pump were employed to propel the distilled water and bovine whole blood to a high flux dialyzer. Pressures at the dialyzer inlet and outlet in the blood circuit and in the dialysate circuit were measured, respectively. From these data, we calculated the transmembrane pressure and predicted the ultrafiltration and backfiltration rates developed by both pumps. Using the bovine's blood experiment, ultrafiltration and backfiltration rates were 1.6 times higher with the pulsatile pump than with the roller pump. We conclude that utilization of a pulsatile pump in high flux hemodialysis treatments increases ultrafiltration volume, compared with a roller pump under conditions of the same blood flow rate.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2009년 추계학술대회논문집
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• pp.38-43
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• 2009

The objective of this study is to get a fundamental data for the shape of a robot which operates in blood vessels. The overall analysis was calculated with a CFD code. The flow was idealized as a pulsatile flow, and first the robot was assumed as a simple capsule model. Then a drag of the body in the flow was calculated, and this process was repeated, varying the shape. To validate all the result, the pulastile velocity simulation was compared with the theoretical data, and the drag of a body was compared with the existing data of the other papers first. Then with the next calculation the guideline for the design of robot shape was presented.

• Journal of applied mathematics & informatics
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• 제10권1_2호
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• pp.193-207
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• 2002

The present investigation deals with the pulsatile flow of incompressible viscous fluid through a circular rigid tube provided with constriction. The method applied here is the Decomposition Method, which has been developed by George Adomian [3]. The advantages of this method are the avoidance of simplifications and restrictions, which change the non-linear problem to mathematically tractable one, whose solution is not consistent with physical solution. Theoretically results, such as, wall shear stress and axial velocity component, have been obtained and the graphical solutions of these theoretical results have been shown in the figures.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 춘계학술대회
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• pp.1936-1941
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• 2003

Characteristics of the high frequency and pulsatile flow investigated experimentally to understand the flow phenomena in the hydraulic system. In the study, I axis fatigue tester which are widely used for automobile filed are selected. 4 Pressure transducer, amplifier, A/D convertor are used to analyse and to obtain the pulsatle pressure waveform with high frequencies in hydraulic system. Matlab are used. to analyse the characteristics of frequency. Variation of pump input pressure and actuator acceleration frequency, pressure wave are measured with or without accumulators. For with accumulator, frequency amplitude of pressure are very lower than those of without accumulator due to absorbing function of accumulator. As the actuator acceleration frequency increased, effect of accumulator are very important to decrease the pulsatile pressure waveform with high frequencies.