• 제목/요약/키워드: public medicine

검색결과 7,430건 처리시간 0.032초

랫드와 비글에서 GC-100X 세정제의 독성에 대한 연구 (Toxicity study of GC-100X in rats and beagles)

  • 강경선;조성대;안남식;정지원;양세란;박준석;박기수;홍인선;서민수;조은혜;;이영순
    • 대한수의학회지
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    • 제44권1호
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    • pp.29-40
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    • 2004
  • Because cleaning products are part of our everyday lives, it is essential that they should not present significant risks to health. However, many petrochemicals in most soaps and detergents can be absorbed through the scalp and skin and, over time, accumulate in the organs and tissues. This accumulation may result in brain, nerve, and liver damage. Therefore, it is interested in developing non-harmful detergent. According to Korea Research Institute of Chemical Technology, GC-100X may be non-harmful and non-corrosive alkaline ionic water (pH 12). It is composed of hydroxyl radicals and supplemented with xylitol. To evaluate influence of GC-100X on rats and beagles, GC-100X was diluted with distilled water (25%, 50%, and 100% solution respectively). Each of diluted GC-100X was daily treated per oral. In body weight analysis, urinary analysis, ophthalmological test and autopsy, we did not find any significance, but in serum biochemical analysis and hematological analysis, we found some significances in middle dose group compared with control group. These significances in serum biochemical analysis and hematological analysis may be not induced by GC-100X, because it was not found to be significant from control group in histopathological examination. Thus, it is concluded that NOEL(No Observed Effect Level) of GC-100X may be higher than all treatment doses used in this study, and GC-100X may be a non-toxic detergent.

Inhibition of human breast carcinoma by BLC (Sargassum fulvellum) and BLC/HEN Egg in vitro and in vivo

  • Jo, Eun-Hye;Cho, Sung-Dae;Ahn, Nam-Shik;Jung, Ji-Won;Yang, Se-Ran;Park, Joon-Suk;Hwang, Jae-Woong;Lee, Sung-Hoon;Park, Jung-Ran;Kim, Sun-Jung;Park, Hyun-Kyung;Lee, Yong-Soon;Kang, Kyung-Sun
    • 대한수의학회지
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    • 제45권1호
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    • pp.85-91
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    • 2005
  • Much of the interest on the chemopreventive properties of herbs and plants has been raised, whereas little is regarding to anti-tumor effect of farming and aquatic products. In the present study, the anti-tumor effect of hot-water extract of a seaweed, BLC (Sargassum fulvellum) and BLC/HEN egg was investigated using MCF-7 cells in vitro and in vivo systems. We found that the BLC extract and BLC/HEN egg inhibited cell proliferation in a dose-dependent manner, which might be mediated through up-regulation of p53. Furthermore, this test compound can directly induce apoptosis in MCF-7 cells, which might be mediated through up-regulation of a pro-apoptotic Bax protein and down-regulation of a anti-apoptotic Bcl-2 protein, not by immune system. Nude mice bearing established breast tumors (with exogenous estradiol) were treated with BLC extract and BLC/HEN egg. Treatment BLC extract and BLC/HEN egg caused a 42% and 71% inhibition of tumor growth, respectively. Both agents caused a significant inhibition of volume and weight growth of estrogen independent human breast tumors established from MCF-7 cells. Our results suggested that BLC extract and BLC/HEN egg have the efficacious effect of human breast cancer not only in vitro but also in vivo.

국내 한의약공공보건사업 최근 연구 분석 (The Analysis of the Recent Research of Korean Medicine Public Health Promotion Programs in Korea)

  • 김경한;송현종;김지우;장보형;신용철;고성규
    • 대한예방한의학회지
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    • 제18권2호
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    • pp.1-10
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    • 2014
  • Objective : The aim of this study is to analyze the recent research of Korean Medicine(KM) public health promotion programs in Korea. Method : We searched the study using Korean Medicine Information System, Research Information Service System and Korean Studies Information Service. We analyzed studies by research content, publication year and type of journal. Results : Analysis by research contents, it was divided into survey research, policy research, development research and evaluation research. Analysis by publication year, little research had been conducted from 1990 until 2000 and most of the research was done since 2000. Analysis by type of journal, 53% of studies published by journals related with KM. Conclusion : Development and evaluation research of KM public health promotion programs should be actively conducted. It is also need to establish the foundation in which KM public health promotion programs would be expanded not only KM field but also in other fields.

도시의 노인보건방문서비스를 위한 자원 및 모델 개발에 관한 연구 (Research and Development of Urban Health Infrastructure for Home Health Care for the Elderly)

  • 강복수;황인수;김창윤;김석범;이경수
    • 농촌의학ㆍ지역보건
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    • 제21권1호
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    • pp.47-60
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    • 1996
  • Home health care is one of the important components of health care services. Today, the need and demand for the home health care is increasing. To assess the effects of home visit health services by public health nurses in health center on the stat of health, use of medical services and quality of life by elderly people living at home, a randomized controlled trial was implemented for 65 years or more old people randomly allocated to intervention(93) and control(118) group. Intervention group received 2 visits a month over 6 months. Control group received no home visits. The data was collected in a one-year follow-up survey conducted at Kyongju before and after the intervention which composed of health risk assessment, risk factor education and health related behavior counseling. The prevalence rate of chronic illness was more decreased in intervention group than control group after intervention. The intervention group visited medical facilities less frequently than control group. And the home visit health services encouraged the elderly to practice regular exercise. After the intervention, the score of ADL(activities of daily living), LSI(life satisfaction index) and SSI(social support index) in intervention group were more increased than control group. And the increase of scores was more prominent in 70 years or more old people, female, non-smoker and non-chronic illed elderly rather than others. In conclusion, the regular home visit health services provided by public health nurses were beneficial for the elderly in terms of health promotion and quality of life.

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