• Journal of Korean Neurosurgical Society
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• 제50권2호
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• pp.114-118
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• 2011

Objective : The purpose of this study is to confirm whether brain disease or brain trauma actually affect psychopathology in young male group in Korea. Methods : The authors manually reviewed the result of Korean military multiphasic personal inventory (KMPI) in the examination of conscription in Korea from January 2008 to May 2010. There were total 237 young males in this review. Normal volunteers group (n=150) was composed of those who do not have history of brain disease or brain trauma. Brain disease group (n=33) was consisted of those with history of brain disease. Brain trauma group (n=54) was consisted of those with history of brain trauma. The results of KMPI in each group were compared. Results : Abnormal results of KMPI were found in both brain disease and trauma groups. In the brain disease group, higher tendencies of faking bad response, anxiety, depression, somatization, personality disorder, schizophrenic and paranoid psychopathy was observed and compared to the normal volunteers group. In the brain trauma group, higher tendencies of faking-good, depression, somatization and personality disorder was observed and compared to the normal volunteers group. Conclusion : Young male with history of brain disease or brain trauma may have higher tendencies to have abnormal results of multiphasic personal inventory test compared to young male without history of brain disease or brain trauma, suggesting that damaged brain may cause psychopathology in young male group in Korea.

• 생물정신의학
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• 제21권1호
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• pp.28-35
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• 2014

Objectives This study aimed to identify the relationship between quality of life (QoL) and psychosocial factors of schizophrenia patients registered in a community mental health center. Methods The ninety patients with schizophrenia, diagnosed by Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition-Text Revision, registered in a community mental health center were studied cross-sectionally. Four trained personnels interviewed each subject individually for the assessment of QoL, psychopathology, severity of depressed mood, insight of illness, attitude toward drugs, social function, degree of social supports and conflicts. Results QoL was significantly related to the psychopathology, depressed mood, social conflict, social support; and other aspects of QoL were slightly differently related to depressed mood, social conflict, social support and attitude toward drug by scales. In multiple regression analysis, depressed mood (20.0%) and social conflict (10.3%) were contributed to QoL assessed by Korean version of 4th revision of Schizophrenia Quality of Life. Social support (21.4%), social conflict (20.9%) and depressed mood (3.1%) were contributed to QoL assessed by Korean modification of the Scale to measure Subjective Well-being under Neuroleptic treatment. Conclusions These findings demonstrated that QoL of schizophrenia patients in a community is affected by depressed mood, social support and conflict rather than psychotic symptoms, insight and attitude toward drugs. And this result suggests the necessity of approaching not only to the psychotic symptoms but also to the psychosocial characteristics in caring schizophrenia patients in the community.

• 정신신체의학
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• 제8권2호
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• pp.149-164
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• 2000

신체화는 진단보다는 오히려 일종의 과정으로 간주된다. 따라서 단순히 진단명을 선택하기보다는 정신병리를 알아 보려는 노력이 더 중요하다. 신체형장애의 진단 및 치료의 어려움은 환자의 질병행동 즉 정신사회적 문제를 부정하여 정신과적 접근을 기피하는 것과 밀접한 관계가 있다. 신체증상 이면에 있는 정신사회적 문제에 대한 단서를 포착하는 것은 정신과의사의 중요한 역할이다. 이런 점에서 신체화 환자들에 대한 치료적 접근은 정신과적 치료에 대한 수용을 촉진할 수 있는 특정 기술과 전략이 요구된다. 신체화 환자의 치료목표는 완치가 아니라 관리에 있다. 치료는 환자의 반응과 필요성에 따라 융통성을 두어야 한다. 평가 및 치료 초기부터 여러 과가 공동으로 접근하는 것이 효과적이다. 결론적으로 신체화의 평가 및 치료는 통합적인 접근 즉 생물정신사회적인 접근이 필요하다. 특히 다른 신경증 환자에서보다는 생물의학적 접근이 더 강조될 필요가 있다. 따라서 이런 환자들을 조기에 발견하고 환자의 정신과적 치료의 수용을 촉진시키기 위해서는 신체형환자에게 적절한 접근 즉 면담기술을 개발해야 함은 물론 다른과 의사들을 교육시키는 것도 정신과의사가 해야 할 중요한 역할에 속한다.

• 정신신체의학
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• 제25권2호
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• pp.95-100
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• 2017

연구목적 탈북 청소년의 정신병리와 자살 관련 특성과의 관계를 알아보고자 이 연구를 수행하였다. 방 법 국내에 입국 후 대안학교에 재학중인 탈북 청소년 104명을 대상으로 연구를 수행하였다. 한글판 역한연구센터 우울척도, 한글판 Revised Children's Manifest Anxiety Scale, 한글판 Rosenberg Self-Esteem Scale와 함께 자살 사고, 자살 계획, 자살 시도에 대한 유무룰 조사하였다. 결 과 자살 사고를 경험한 탈북청소년은 21명으로 전체의 20.19% 이었으며, 우울 증상(Z=-4.050, p<0.001), 불안 증상(Z=-2.076, p<0.05), 자존감(Z=-2.328, p<0.05)은 자살 사고의 유무에 따라 통계학적으로 유의한 차이가 관찰되었다. 로지스틱 회귀분석 결과 우울 증상(p<0.05)이 통계학적으로 유의하게 자살 사고를 예측하였다. 결 론 탈북 청소년의 우울과 불안에 대한 관심이 탈북 청소년의 자살에 대한 도움을 주는데 기여할 수 있을 것이다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제23권3호
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• pp.127-133
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• 2012

Objectives : The aims of this study were to examine agreement between parent and teacher ratings of the Korean version Strengths and Difficulties Questionnaire (SDQ-Kr) for the children's psychopathology and to determine whether it is effective in diagnostics as the Korean version of Childhood Behavior Checklist (K-CBCL). Methods : SDQ-Kr and K-CBCL were completed by parents and teachers of 165 children aged 6-12 years. The clinical diagnosis was made by a child and adolescent psychiatrist who did not have knowledge of the outcome. Spearman's correlations were computed for associations between parents' and teachers' ratings on a subscale level. The Mann-Whitney U test was performed for the influence of child's age and sex on the results. Finally, AUC values were calculated for the diagnostic capacity and the difference between informants was tested using the z test. Results : High correlations were observed between parents' and teachers' SDQ-Kr on every scale. Parents were more sensitive to emotional symptoms of girls, while teachers appeared to be more responsive to externalized symptoms of boys, inattention-hyperactivity of young children, and emotional symptoms of seniors. Parents' SDQ-Kr demonstrated the highest prediction of attention-deficit hyperactivity disorder. Conclusion : Teachers' SDQ-Kr can be used in identification of child psychopathology when parents are absent or when their reliability is considered low.

• 대한불안의학회지
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• 제11권2호
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• pp.120-128
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• 2015

Objectives : The Minnesota Multiphasic Personality Inventory (MMPI) is a commonly used psychological test measuring personality and psychopathology in both clinical and non-clinical population. This study was to evaluate characteristic MMPI-2 profile associated with the risk of suicide among college students. Methods : We analyzed the survey response of 2,964 college students who participated in a health survey from a school health center at a national university in 2011. Those who endorsed any of six items on the suicidaity module of MINI were classified as a suicide risk group and remaining students who did not as a control group. Then we compared the Patient Health Questionnaire (PHQ-9) score, the MMPI-2 Clinical scales and Restructured Clinical (RC) scales. To evaluate the correlation RC scales with suicidality score, Pearson correlation analysis was performed. Results : The suicide risk group was 464 students, and the control group was 2,500. The classification result of suicidality, 255 (8.6%) students were low-risk group, 149 (4.8%) students were moderate-risk group and 60 (2.0%) students were high-risk group. In the suicide risk group, VRIN, F scale, Clinical scale and RC scales were significantly higher. In the control group L, K and S scales were significantly higher. Suicidality score has significant correlation with all RC scales. Conclusion : In the suicide risk group, overall psychopathology was higher than the control group. Taken together, features of depressive symptom, antisocial behavior, aggressiveness, introversion may indicate the risk of suicide in college students. These results display both clinical and public health implications for clinicians and school health professionals.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제12권2호
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• pp.275-281
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• 2001

본 연구에서는 아동의 발달적 측면을 고려하면서, ADHD 아동의 정신 병리(우울, 불안, 공격성) 수준과 부적응적 인지 특성(인지 오류, 귀인 편파)의 관계를 탐색하였다. 병원을 내원하여 주진단이 ADHD인 40명의 아동과 아동의 어머니는 아동의 우울, 불안, 공격성과 부적응적인 인지 특성들을 평가하는 질문지를 작성하였다. 연구 결과, ADHD 아동의 우울과 불안, 공격성 수준과 부적응적 인지 특성은 유의미한 상관을 보이지 않았다. 연령은 우울증에 특징적인 부적응적인 귀인 특성인 부정적인 사건에 대한 내적 안정적 귀인 경향과 부적인 상관을 보였으며, 연령은 부정적인 사건에 대한 내적 안정적 귀인 경향에 유의미한 영향을 미쳤다. ADHD 아동은 연령이 높아짐에 따라 부정적인 사건에 대해 내부 귀인을 하는 경향이 줄어들었으며, 이들의 우울이나 불안 증상은 부적응적인 인지 특성과 관련되기보다는 그 당시에 직면한 스트레스 사건과 연관된 것일 가능성이 있겠다. 본 연구결과의 시사점과 제한점, 앞으로의 연구방향이 논의되었다.

• 대한불안의학회지
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• 제2권2호
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• pp.122-127
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• 2006

Objective : We examined the putative association between the psychological symptoms and hypoxemia in hospitalized pneumoconiosis patients. Methods : One hundred and nine hospitalized pneumoconiosis patients were divided into two groups according to their level of hypoxemia (PaO2); hypoxemic group consisted of 47 patients with PaO2 lower than 80 mmHg, and comparative group consisted of 62 patients with higher than 80 mmHg. All of them were interviewed with the Hamilton Depression Rating Scale (HAM-D), and completed the Symptom Checklist-90items-Revised (SCL-90-R) and the State-Trait Anxiety Inventory (STAI). The medical data (PaO2, PaCO2, Hb, and Hct), number of hospital days and socio-demographic data as well as scores of the three psychological measurements were compared between the two groups. Results : Hypoxemic patients with lower PaO2 showed higher scores in the HAM-D (p=0.01) and stateanxiety subscale of the STAI (p<0.05). Values of hemoglobin and hematocrit were negatively correlated with levels of trait-anxiety (p<0.05). Thirty patients (27.5%) of total subjects suffered from depression (higher than 18 in the HAM-D), and 46.8% of hypoxemic patients were depressed, whereas 12.9% of comparative group patients were depressed (p=0.01). Conclusion : These results suggest that depression and anxiety might be associated with the hypoxemic mechanism in pneumoconiosis patients.

• Journal of Korean Neurosurgical Society
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• 제54권5호
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• pp.390-398
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• 2013

Objective : We determined whether the relationship between the neuropsychological performance of patients with mild traumatic brain injury (TBI) and their psychopathological characteristics measured by disability evaluation are interrelated. In addition, we assessed which psychopathological variable was most influential on neuropsychological performance via statistical clustering of the same characteristics of mild TBI. Methods : A total of 219 disability evaluation participants with mild brain injury were selected. All participants were classified into three groups, based on their psychopathological characteristics, via a two-step cluster analysis using validity and clinical scales from the Minnesota Multiphasic Personality Inventory (MMPI) and Symptom Checklist-90-revised (SCL-90-R). The Korean Wechsler Adult Intelligence Scale (K-WAIS), Korean Memory Assessment Scale (K-MAS) and the Korean Boston Naming Test (K-BNT) were used to evaluate the neurocognitive functions of mild TBI patients. Results : Over a quarter (26.9%) experienced severe psychopathological symptoms and 43.4% experienced mild or moderate psychopathological symptoms, and all of the mild TBI patients showed a significant relationship between neurocognitive functions and subjective and/or objective psychopathic symptoms, but the degree of this relationship was moderate. Variances of neurocognitive function were explained by neurotic and psychotic symptoms, but the role of these factors were different to each other and participants did not show intelligence and other cognitive domain decrement except for global memory abilities compared to the non-psychopathology group. Conclusion : Certain patients with mild TBI showed psychopathological symptoms, but these were not directly related to cognitive decrement. Psychopathology and cognitive decrement are discrete aspects in patients with mild TBI. Furthermore, the neurotic symptoms of mild TBI patients made positive complements to decrements or impairments of neurocognitive functions, but the psychotic symptoms had a negative effect on neurocognitive functions.

• 생물정신의학
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• 제17권2호
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• pp.86-93
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• 2010

Objectives : The aim of this research is to determine the effects of depression and anxiety symptoms of schizophrenic psychopathology on the HPA axis. Methods : Twenty patients with schizophrenia were included and divided into the medication non-exposed group(n = 10) and the medication exposed group(n = 10). Evaluated scales were the Positive and Negative Syndrome Scale(PANSS), Scale for the Assessment of Negative Symptoms(SANS), Scale for the Assessment of Positive Symptoms(SAPS), Hamilton Depression Inventory(HAM-D) and Hamilton Anxiety Inventory (HAM-A), and then the combined Dexamethasone/Corticotropin Releasing Hormone(DEX/CRH) test was conducted to determine the basal level, the peak level and the area under the curve(AUC) of cortisol and adrenocorticotropic hormone(ACTH). Results : When the correlations between each psychopathology and cortisol level or ACTH AUC value were analyzed, HAM-D showed a negative correlation, whereas HAM-A showed a positive correlation. Also, the non-depression group(HAM-D ${\leq}$ 18) showed higher cortisol and ACTH concentrations than the depression group(HAM-D > 18), and the anxiety group(HAM-A ${\geq}$ 14) showed significantly higher concentrations than the non-anxiety group(HAM-D < 14)(p < 0.05). Also, as for the comparison between the medication non-exposed group and the medication exposed group, the non-exposed group showed significantly higher cortisol and ACTH concentration than exposed group(p < 0.05). Conclusion : This study suggest that anxiety symptoms rather than depression symptoms are related to the increased activity of the HPA axis of schizophrenics.