• 폴리머
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• 제38권4호
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• pp.491-495
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• 2014

UV조사에 의한 2-EHA(ethylhexyl acrylate)/AA(acrylic acid) 점착제를 제조하고 이때 첨가되는 광 개시제의 종류가 점차제의 접착물성에 미치는 영향을 조사하였다. Irgacure$^{(R)}$651(benzyldimethyl ketal)과 Irgacure$^{(R)}$184(1-hydroxy-cyclohexylphenyl ketone) 광 개시제를 도입한 점차제의 경우 UV램프의 방출 스펙트럼 근처에서의 높은 흡수율과 단량체 혼합물과의 상용성에 기인하여 우수한 접착물성을 나타낸 반면 Irgacure$^{(R)}$819(bisacylphosphine oxides) 광 개시제를 도입한 경우 사용된 UV램프의 방출 스펙트럼과 가장 겹치는 흡수 파장대를 가짐에도 불구하고 고농도에서 박리 시 응집파괴가 일어났으며 이것은 높은 함량에서 광 개시제 일부가 산소와 반응하고 이것이 수소 공여체 역할을 하여 추가적인 라디칼 형성을 일으키기 때문으로 생각된다.

• Bulletin of the Korean Chemical Society
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• 제31권6호
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• pp.1561-1567
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• 2010

In this study, we have developed a new detection method using Si field effect transistor (FET)-type biosensors, which enables the direct monitoring of antigen-antibody binding within very high-ionic-strength solutions such as 1$\times$PBS and human serum. In the new method, as no additional dilution or desalting processes are required, the FET-type biosensors can be more suitable for ultrasensitive and real-time analysis of raw sample solutions. The new detection scheme is based on the observation that the strength of antigen-antibody-specific binding is significantly influenced by the ionic strength of the reaction solutions. For a prostate specific antigen (PSA), in some conditions, the binding reaction between PSA and anti-PSA in a low-ionic strength reaction solution such as 10 ${\mu}M$ phosphate buffer is weak (reversible), while that in high-ionic strength reaction solutions such as 1$\times$PBS or human serum is strong.

• 한국안전학회지
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• 제33권6호
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• pp.136-143
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• 2018

In this study, we conducted a pilot study on the multiple spurious operations (MSO) analysis in the fire probabilistic safety assessment (PSA) of domestic nuclear power plant (NPP) to identify the degree of influence of the operator actions used in the MSO mitigation strategies. The MSO scenario of the domestic reference NPP selected for this study is refueling water tank (RWT) drain down event. It could be caused by spurious operations of the containment spray system (CSS) of the reference NPP. The RWT drain down event can be stopped by the main control room (MCR) operator actions for stopping the operation of CSS pump or closing the CSS motor operated valve if the containment spray actuation signal (CSAS) is spuriously actuated. Outside the MCR, it can be stopped by operator actions for closing the CSS manual valves or motor operated valve or stopping the operation of CSS pump. The quantification result of a fire PSA model that takes into account all recovery actions for the RWT drain down event lead to risk reduction by about 95%, compared with quantification result of fire PSA model without considering them. Among the various operator actions, the recovery action for the spurious CSAS operations and the operator action for the manual valve are identified as the most important operator actions. This study quantitatively showed the extent to which the operator actions used as MSO countermeasures have affected the fire PSA quantification results. In addition, we can see the rank of importance among the operator recovery actions in quantitative terms.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2007년도 춘계학술대회B
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• pp.3464-3466
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• 2007

Power uprate is the process of increasing the maximum power level at which a commercial nuclear power plant may operate. Power uprate applications(113 units) for NPPs(Nuclear Power Plants) were recently approved in the United States. Utilities have been using power uprates since the 1970s as a way of increasing the power output of their nuclear plants. To increase the power output of a reactor, typically more highly enriched uranium fuel and/or more fresh fuel is used. This enables the reactor to produce more thermal energy and therefore more steam, driving a turbine generator to produce electricity. In this paper, the propriety of power uprate is explained through the review on the power uprate method and the changes of the physical parameters due to power uprate. The analysis results showed that the CDF(Core Damage Frequency) and LERF(Large Early Release Frequency) are affected in the current probabilistic safety assessment (PSA) model.

• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.9841-9846
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• 2014

Objectives: To compare the metabolic indices, lipid profile, androgens, and prostate specific antigen between prostate cancer and BPH and between grades of prostate cancer in a cross-sectional study. Materials and Methods: The study enrolled 95 cases of prostate cancer and 95 cases of benign prostatic hyperplasia (BPH). Prostate gland volume was measured using transrectal ultrasound. We compared insulin, testosterone, dihydrotestosterone, prostate specific antigen levels and lipid profile between prostate cancer of different grades and BPH. Further, prostate cancer patients were classified into low grade and high grade. Unpaired t-test for normally distributed variables and Man-Whitney U test for non-normal variables were used to assess differences. Results: We found that prostate cancer patients had significantly higher levels of insulin, testosterone, PSA, cholesterol, triglycerides, low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) in comparison to their BPH counterparts. Higher levels of these parameters also correlated with a higher grade of the disease. Conclusions: We conclude that higher levels of insulin, testosterone, PSA, and cholesterol correlate with a higher risk of prostate cancer, and also with a higher grade of the disease.

• ETRI Journal
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• 제43권5호
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• pp.941-949
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• 2021

In this study, a spatial spectrum method is proposed to cope with the pilot spoofing attack (PSA) problem by exploiting the of uplink-downlink channel reciprocity in time-division-duplex multiple-input multiple-output systems. First, the spoofing attack in the uplink stage is detected by a threshold derived from the predefined false alarm based on the estimated spatial spectrum. When the PSA occurs, the transmitter (That is Alice) can detect either one or two spatial spectrum peaks. Then, the legitimate user (That is Bob) and Eve are recognized in the downlink stage via the channel reciprocity property based on the difference between the spatial spectra if PSA occurs. This way, the presence of Eve and the direction of arrival of Eve and Bob can be identified at the transmitter end. Because noise is suppressed by a spatial spectrum, the detection performance is reliable even for low signal-noise ratios and a short training length. Consequently, Bob can use beamforming to transmit secure information during the data transmission stage. Theoretical analysis and numerical simulations are performed to evaluate the performance of the proposed scheme compared with conventional methods.

• Nuclear Engineering and Technology
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• 제54권12호
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• pp.4601-4619
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• 2022

The classical Probabilistic Safety Analysis (PSA) does not include any time dependence explicitly. However, the success criteria (SC) could evolve during the cycle for some initiating events. In that sense, there is a type of sequence in which this time-dependency is quite important, the family of Anticipated Transient without Scram (ATWS) sequences in Pressurized Water Reactors. Therefore, a new risk-informed approach is proposed in this paper, which makes it possible to obtain the time-dependent SC evolution of the safety functions affected by the Moderator Temperature Coefficient (MTC) value. Then, the evolution of the ATWS conditional core damage probability (CCDP) could be obtained using a PSA model. To quantify the CCDP, the average values of the time-dependent failure probabilities must be computed. Finally, the comparison between the CCDP obtained through the application of the classical PSA approach and the new one makes it possible to quantify the impact of time-dependence on the SC of the headers that this new risk-informed ATWS approach can provide.

• 청정기술
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• 제19권4호
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• pp.370-378
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• 2013

본 논고에서는 가스 흡착 분리 산업에서 광범위하게 적용되고 있는 압력순환흡착(pressure swing adsorption, PSA) 기술의 전형적인 흡착조건인 $15{\sim}40^{\circ}C$의 온도와 4~6 bar의 압력에서 금속-유기 골격체(metal-organic frameworks, MOF)와 제올라이트 이미다졸레이트 골격체(zeolite imidazolate frameworks, ZIF)의 $CO_2$ 흡착성능을 살펴보고 이들이 가지고 있는 장 단점을 분석해보고자 한다. $CO_2$는 $H_2$, CO, $N_2$ 및 $CH_4$와 같은 기체분자들에 비해 큰 분극률을 가지므로 동일한 세공크기라면 흡착제의 비표면적이 클수록 높은 흡착량을 보이며, $CO_2$의 분자크기($3.3{\AA}$)보다 큰 세공으로 이루어진 흡착제라면 상기 흡착조건에서의 $CO_2$ 흡착성능은 세공크기에 크게 영향을 받는다. MOF와 ZIF의 $CO_2$ 흡착성능은 이들의 골격을 이루는 금속과 유기 링커의 종류, 세공크기, 비표면적, 흡착조건(온도와 압력) 등에 따라 달라질 수 있지만, 특히 흡착압력의 영향이 절대적이다. 다시 말하면, $CO_2$의 흡착압력이 비슷할 경우 MOF와 ZIF의 $CO_2$ 흡착량에 미치는 상기 인자들의 영향은 비교적 작다. 15 bar 이상의 $CO_2$ 흡착압력에서 이 흡착제들이 수 십 mmol/g의 흡착성능을 나타낸다고 할지라도, 전형적인 PSA 공정조건에서 이들의 $CO_2$ 흡착성능은 제올라이트, 활성탄과 같은 벤치마크 흡착제들의 성능과 유사하거나 오히려 낮을 뿐만아니라, 이들의 가격은 벤치마크들에 비해 매우 높기 때문에 경제성 확보에 어려움이 있다.

• 한국안전학회지
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• 제32권3호
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• pp.160-171
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• 2017

US national research laboratories developed the first Vital Area Identification (VAI) method for the physical protection of nuclear power plants that is based on Event Tree Analysis (ETA) and Fault Tree Analysis (FTA) techniques in 1970s. Then, Korea Atomic Energy Research Institute proposed advanced VAI method that takes advantage of fire and flooding Probabilistic Safety Assessment (PSA) results. In this study, in order to minimize the burden and difficulty of VAI, (1) a set of streamlined VAI rules were developed, and (2) this set of rules was applied to PSA fault tree and event tree at the initial stage of VAI process. This new rule-based VAI method is explained, and its efficiency and correctness are demonstrated throughout this paper. This new rule-based VAI method drastically reduces problem size by (1) performing PSA event tree simplification by applying VAI rules to the PSA event tree, (2) calculating preliminary prevention sets with event tree headings, (3) converting the shortest preliminary prevention set into a sabotage fault tree, and (4) performing usual VAI procedure. Since this new rule-based VAI method drastically reduces VAI problem size, it provides very quick and economical VAI procedure. In spite of an extremely reduced sabotage fault tree, this method generates identical vital areas to those by traditional VAI method. It is strongly recommended that this new rule-based VAI method be applied to the physical protection of nuclear power plants and other complex safety-critical systems such as chemical and military systems.

• The Korean Journal of Physiology and Pharmacology
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• 제17권5호
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• pp.405-409
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• 2013

We studied the sex different nicotine effect on evoked population spike amplitudes (ePSA) and connexin (Cx) expression in the hippocampus CA1 area of gerbils. Acute doses of nicotine bitartrate (0.5 mg/kg: NT-0.5) slightly reduced ePSA in males but markedly augmented that in females. Acute NT (5.0 mg/kg) markedly increased the ePSA in all gerbils. Unlike acute NT-0.5, repeated NT-0.5 injection (twice a day for 7 days) significantly increased the ePSA in males and slightly affected the NT-0.5 effect in females. The Cx36 and Cx43 expression levels as well as Cx expressing neuronal populations were significantly increased by repeated NT-0.5 in in both male and female gerbils, and particularly, Cx43 expression was somewhat prominent in females. These results demonstrated a sex difference with respect to the nicotine effect on hippocampal bisynaptic excitability, irrelevant to connexin expression.