• 대한감각통합치료학회지
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• 제14권1호
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• pp.41-49
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• 2016

목적 : 본 연구는 뇌성마비 아동에게 신경발달치료 접근법을 기초한 옷 벗기 기술 훈련에 따른 신체중심선과 보호반응에 미치는 효과를 알아보고자 하였다. 연구방법 : 연구대상은 B시에 거주하는 만 3세 5개월 남아와 만 4세 5개월 여아로 뇌성마비 진단을 받았다. 본 연구는 단일대상연구 중 AB 디자인을 사용하였고, 기초선 기간(A) 2회, 중재 기간(B) 10회로 총 12회기를 실시하였다. 중재는 신경발달치료 접근에 기초한 옷 벗기 훈련을 실시하였고, 평가로 신체중심선은 Miller Assessment for Preschoolers(MAP)의 하위 항목인 Stepping 항목을 사용하였으며, 보호반응은 Quality Upper Extremity Skill Test(QUEST) 검사의 하위 항목인 보호반응 항목을 사용하였다. 결과 : 아동의 신체중심선은 기초선 기간과 비교하여 중재기간이 2표준편차 이상으로 감소하였다. 보호반응은 오른쪽과 왼쪽 모두 중재기간 평균점수가 기초선 평균점수보다 높게 나타났다. 결론 : 뇌성마비 아동에게 신경발달치료접근법을 기초한 옷 벗기 기술 훈련이 신체중심선 향상에 효과적이었다. 앞으로 집단 연구를 통하여 그 효과를 확인하는 것이 필요할 것이다.

• 한국주조공학회지
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• 제30권6호
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• pp.231-234
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• 2010

The effect of $C_2Cl_6$ for preventing to the surface oxidation and ignition of molten Mg alloy was studied with metallographic analysis, X-ray diffraction, scanning electron microscopy and energy dispersive spectroscopy. The alloy used for this study was AM100A Mg casting alloy with high strength. In order to investigate the surface protective characteristic of this molten alloy by $C_2Cl_6$ addition, we added them into molten AM100A alloy at $700^{\circ}C$ and then the melts were slowly cooled under a protective atmosphere of air containing Ar gas and $C_2Cl_6$ flux addition. The result found that the surface oxidation and ignition reaction of molten AM100A Mg alloy by adding $C_2Cl_6$ flux was more slowly occurred than that of the only a protective atmosphere of containing Ar gas with increasing time. This result was due to a dense protective film formed containing $MgCl_2$ on surface of molten Mg alloy during casting and solidification. The $MgCl_2$ was formed by a reaction of $C_2Cl_6$ with molten Mg.

• Journal of Electrochemical Science and Technology
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• 제14권2호
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• pp.162-173
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• 2023

Aqueous zinc-ion batteries are considered as promising alternatives to lithium-ion batteries for energy storage owing to their safety and cost efficiency. However, their lifespan is limited by the irreversibility of Zn anodes because of Zn dendrite growth and side reactions such as the hydrogen evolution reaction and corrosion during cycling. Herein, we present a strategy to restrict direct contact between the Zn anode and aqueous electrolyte by fabricating a protective layer on the surface of Zn foil via phosphidation method. The Zn₃(PO₄)₂ protective layer effectively suppresses Zn dendrite growth and side reactions in aqueous electrolytes. The electrochemical properties of the Zn₃(PO₄)₂@Zn anode, such as the overpotential, linear polarization resistance, and hydrogen generation reaction, indicate that the protective layer can suppress interfacial corrosion and improve the electrochemical stability compared to that of bare Zn by preventing direct contact between the electrolyte and the active sites of Zn. Remarkably, MnO₂ Zn₃(PO₄)₂@Zn exhibited enhanced reversibility owing to the formation a stable porous layer, which effectively inhibited vertical dendrite growth by inducing the uniform plating of Zn²⁺ ions underneath the formed layer.

• Journal of Microbiology and Biotechnology
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• 제34권7호
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• pp.1544-1549
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• 2024

This study presents a fluorescent mechanism for two-step amplification by combining two widely used techniques, exponential amplification reaction (EXPAR) and catalytic hairpin assembly (CHA). Pseudomonas aeruginosa (P. aeruginosa) engaged in competition with the complementary DNA in order to attach to the aptamer that had been fixed on the magnetic beads. The unbound complementary strand in the liquid above was utilized as a trigger sequence to initiate the protective-EXPAR (p-EXPAR) process, resulting in the generation of a substantial quantity of short single-stranded DNA (ssDNA). The amplified ssDNA can initiate the second CHA amplification process, resulting in the generation of many double-stranded DNA (dsDNA) products. The CHA reaction was initiated by the target/trigger DNA, resulting in the release of G-quadruplex sequences. These sequences have the ability to bond with the fluorescent amyloid dye thioflavin T (ThT), generating fluorescence signals. The method employed in this study demonstrated a detection limit of 16 CFU/ml and exhibited a strong linear correlation within the concentration range of 50 CFU/ml to 10⁵ CFU/ml. This method of signal amplification has been effectively utilized to create a fluorescent sensing platform without the need for labels, enabling the detection of P. aeruginosa with high sensitivity.

• BMB Reports
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• 제43권10호
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• pp.683-687
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• 2010

Previous studies have shown that one of the primary causes of increased iron content in the brain may be the release of excess iron from intracellular iron storage molecules such as ferritin. Free iron generates ROS that cause oxidative cell damage. Carnosine and related compounds such as endogenous histidine dipetides have antioxidant activities. We have investigated the protective effects of carnosine and homocarnosine against oxidative damage of DNA induced by reaction of ferritin with $H_2O_2$. The results show that carnosine and homocarnosine prevented ferritin/$H_2O_2$-mediated DNA strand breakage. These compounds effectively inhibited ferritin/$H_2O_2$-mediated hydroxyl radical generation and decreased the mutagenicity of DNA induced by the ferritin/$H_2O_2$ reaction. Our results suggest that carnosine and related compounds might have antioxidant effects on DNA under pathophysiological conditions leading to degenerative damage such as neurodegenerative disorders.

• 한방안이비인후피부과학회지
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• 제19권3호통권31호
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• pp.60-67
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• 2006

Objective : Allergic rhinitis is an allergic reaction characterized by sneezing, coughing, itchy nose, mouth and throat, congestion and/or nasal discharge. We aim to observe effect of Sinichengpae-um on protective effects of nasal mucosal tissue in th allergic rhinitis. Method : For this purpose, we oberserved number of leukocyte and erythrocyte in blood, ratio of neutrophil and lymphocyte in leukocyte, activity of GOT and GPT, and histopathologic change of nasal mucose. Result and Conclusion : Sinicheogpae-um showed effects on immune reaction with no harms liver. And in histopathologic change of nasal mucosal tissue, Sinichengpae-um showed significant protective effet against allergic rhinitis.

• Journal of Veterinary Science
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• 제21권5호
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• pp.74.1-74.13
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• 2020

Background: The quality of a vaccine depends strongly on the effects of the adjuvants applied simultaneously with the antigen in the vaccine. The adjuvants enhance the protective effect of the vaccine against a viral challenge. Conversely, oil-type adjuvants leave oil residue inside the bodies of the injected animals that can produce a local reaction in the muscle. The long-term immunogenicity of mice after vaccination was examined. ISA206 or ISA15 oil adjuvants maintained the best immunity, protective capability, and safety among the oil adjuvants in the experimental group. Objectives: This study screened the adjuvant composites aimed at enhancing foot-and-mouth disease (FMD) immunity. The C-type lectin or toll-like receptor (TLR) agonist showed the most improved protection rate. Methods: Experimental vaccines were fabricated by mixing various known oil adjuvants and composites that can act as immunogenic adjuvants (gel, saponin, and other components) and examined the enhancement effect on the vaccine. Results: The water in oil (W/O) and water in oil in water (W/O/W) adjuvants showed better immune effects than the oil in water (O/W) adjuvants, which have a small volume of oil component. The W/O type left the largest amount of oil residue, followed by W/O/W and O/W types. In the mouse model, intramuscular inoculation showed a better protection rate than subcutaneous inoculation. Moreover, the protective effect was particularly weak in the case of inoculation in fatty tissue. The initial immune reaction and persistence of long-term immunity were also confirmed in an immune reaction on pigs. Conclusions: The new experimental vaccine with immunostimulants produces improved immune responses and safety in pigs than general oil-adjuvanted vaccines.

• Tribology and Lubricants
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• 제7권1호
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• pp.16-27
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• 1991

The mechanism of failure of lubricated surfaces at high sliding speeds was investigated. Experiments were performed with the ball-on-flat and cylinder-on-flat geometries, using lubricants of four different chemical reactivities. Surface failure was found to not be predictable using the ratio, $\lambda$, of fluid film thickness to composite surface roughness except when chemically inert lubricants are used. Even then the influence of temperature rise on fluid film thickness does not adequately explain the low load carrying capacity of lubricants at high sliding speeds, which causes surface failure. The protective layers on sliding surfaces that form by chemical reaction with the lubricant were found to reduce the surface roughening and increase the load carrying capacity of surfaces to values of $\lambda$ as low as 0.03. Neither the surface roughening nor the formation of the protective layers have been incorporated into failure models for lubricated systems.

• 시큐리티연구
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• 제3호
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• pp.145-174
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• 2000

Protection activity is divided by the security measures of preventive action and immediately protective reaction in case of emergency situation. The purpose of this study is to emphasis the importance of prevention when providing security for protectees. What I suggested in this thesis is summarized below. Chapter I which sets out purpose, concept, general remarks are followed 3 steps for conducting security action by Chapter II. Chapter III concerns the classification, security technic of preventive action. Classified involving security information, security action, security measures. It is followed site survey, security plan, detailed procedures, coordinative meeting, previous security action, protective action, review meeting by protective technic. Chapter IV consider effective counter plan method of preventive action. Chater V, conclusion.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.242.2-243
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• 2003

We have developed the novel one-pot synthetic method for regioselective N-protected amines, carbamates as a protective group of amines, through the reaction of various ethers with chlorosulfonyl isocyanate (CSJ). This synthetic method provides a simple and convenient alternative for the formation of carbamates, such as -NHMoc, -NHPoc. -NHCbz, -NHPnz, -NHTroc and -NHAloc, by varying the alkyl moiety of ethers. (omitted)