• 한국어병학회지
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• 제6권2호
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• pp.177-189
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• 1993

1. 과산화물가가 90.4mEq/kg인 산화사료에 Vitamin E와 C의 함량을 각각 달리 하여 80일간 Ceroid 예방실험을 행하였다. 2. Ceroid증을 예방하기 위하여 산화사료에 Vitamin C와 E를 첨가한 모든 실험군 및 무첨가한 대조군에서의 성장 비교에서 대조군은 산화사료에 의한 성장 장애가 나타났으나 실험군에서는 정상성장을 보였다. 3. 병리조직학적 관찰에서 대조군은 실험과정 일수에 따라 조직변화가 심하였으나 Vitamin E와 C를 첨가한 실험군별 조직상태는 Vitamin E 1mg/g diet와 Vitamin C 2IU/g diet를 첨가한 실험군에서의 예방효과가 가장 양호하게 나타났다.

• The Korean Journal of Pain
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• 제12권2호
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• pp.246-249
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• 1999

Postherpetic neuralgia (PHN) is defined as the persistence of pain after recovery from herpes zoster (HZ), when the rash has healed, usually after about 4 weeks. PHN is the most feared complication of herpes zoster and remains one of the most common and intractable chronic pain disorders. Recent evidence has shed some light on the possible mechanism of pain, and on the prophylactic and treatment approaches to PHN, but there is no secure therapy. This report is a case of a 70-year-old male with PHN, affecting the 8th to 10th thoracic dermatomes. Patient complains of allodynia and hyperalgesia on the affected skins. After sympathectomy, antidepressant, anticonvulsant, and capsaicin ointment application, much pain relief was achieved, but allodynia remained at the subcostal area about $7\times3 cm^2$ in size. We decided to remove the painful area. Skin excision was done under local anesthesia. After skin excision, the pain was decreased and patient did not complain of pain for 10 months.

• 한국가금학회지
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• 제19권3호
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• pp.151-160
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• 1992

현재 콕시듐 병의 방제는 약제 투여, 사육관리, 백신을 이용하거나 혹은 이들 방법을 적당히 혼합하여 실시하고 있다. 약제 투여 방법은 약의 내성이라는 문제점을 내재하고 있지만 아직도 콕시듐 방제에 최우선 방법으로 쓰고 있으며 이러한 약제 내성을 조금이나마 지연시키기 위하여 shuttle, 혹은 rotation program을 쓰고 있다. 따라서 약제 내성 검사는 각 농장에 어떠한 약제가 효과가 있는지를 알아보는데 가장 중요한 방법이 되어 왔던 것이다. 콕시듐 방제에 있어서 사육관리에 의한 방법은 아직은 완전한 효과적인 방법으로 정착되지 않았는데 그 이우는 소독제만으로는 콕시듐의 원충을 죽일 수 없기 때문이다. 백신에 의한 방법은 현재까지 살아있는 콕시듐 원충을 제한적으로 쓰고 있는 단계이다. 새로운 형태의 백신개발이 요즈음 연구가 되고 있는데 이 백신은 순화시킨 콕시듐 원충을 사용하거나 유전공학적 방법 혹은 원충의 일부분에 대한 항원을 추출하여 백신으로 이용하는 것이다.

• Journal of Korean Neurosurgical Society
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• 제63권3호
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• pp.279-313
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• 2020

This review summarises the classification, anatomy and embryogenesis of complex spinal cord lipomas, and describes in some detail the new technique of total lipoma resection and radical reconstruction of the affected neural placode. Its specific mission is to tackle two main issues surrounding the management of complex dysraphic lipomas : whether total resection confers better long term benefits than partial resection, and whether total resection does better than conservative treatment, i.e., no surgery, for asymptomatic lipomas. Accordingly, the 24 years progression-free survival data of the author and colleagues' series of over 350 cases of total resection are compared with historical data from multiple series (including our own) of partial resection, and total resection data specifically for asymptomatic lesions are compared with the two known series of non-surgical treatment of equivalent patients. These comparisons amply support the author's recommendation of total resection for most complex lipomas, with or without symptoms. The notable exception is the asymptomatic chaotic lipoma, whose peculiar anatomical relationship with the neural tissue defies even our aggressive surgical approach, and consequently projects worse results (admittedly of small number of cases) than for the other two lipoma subtypes of dorsal and transitional lesions. Prophylactic resection of asymptomatic chaotic lipomas is therefore not currently endorsed.

• 한국식품위생안전성학회지
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• 제18권4호
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• pp.171-176
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• 2003

누룩치, 고본, 당귀 및 산초의 ethanol ext.는 자발운동량에 미치는 영향에 대한 시험에서 아무런 영향을 미치지 않았다. 다만 phenobarbital sodium 수면시간에 대해서는 산초투여군에서만 다소 단축시켰다. 0.7% acetic acid의 복강내 투여에 의해 유발된 writhing syndrome을 다소 억제하였으나 유의성은 없었다. 체온에 미치는 영향에 대한 시험에서는 유의성 있는 체온 변화가 없었다. 다만 흰쥐의 위액분비에 미치는 영향에 대한 시험에서는 누룩치와 고본투여군에서 위액분비량과 총산도가 유의적으로 감소하였다. 소장운동능에 미치는 영향에 대한 시험결과 누룩치, 당귀 및 고본투여군에서 유의성 있는 charoal의 이동억제가 관찰되었다. 결론적으로 누룩치, 고본, 당귀 및 산초의 ethanol ext.는 일반약리작용에 대하여 특이한 작용이 없었다.

• 대한한방소아과학회지
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• 제24권2호
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• pp.88-98
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• 2010

Objectives The purpose of this study is to evaluate the clinical effectiveness and prophylactic treatment effectiveness of Gagam-Bopyeyangyeongjeon(GGBYJ) on the Lung Weakness Children(肺系虛弱兒) who catch cold easily. Methods The study has been carried out from 27 children, who were treated with GGBYJ in Department of Pediatrics, $\bigcirc\bigcirc$ Oriental Medical Hospital from August to December in 2009. The study was completed through patient chart review and telephone survey. Results 1. Immediately after the treatment, there was significantly decreasing(p=0.005) on respiratory symptoms in the Lung Weakness Children(肺系虛弱兒) who catch cold easily. 2. After the treatment, when season changes (three months later), there were preventive and continuous effects on reducing morbidity and on decreasing degree of symptoms against new respiratory infections compared to the previous year before taking medicine. 3. GGBYJ improved the respiratory symptoms, and also anorexia, constipation, heights, skin and fatigue. Conclusions In conclusion, there were significant clinical and preventive effectiveness of GGBYJ for the Lung Weakness Children(肺系虛弱兒) who caught a cold easily. Further studies are needed with more clinical cases.

• Journal of Microbiology and Biotechnology
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• 제30권4호
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• pp.477-481
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• 2020

Viability plays an important role in the beneficial microbes (probiotics) to produce health benefits. However, this idea has been changed after the invention of the term "paraprobiotics," indicating that non-viable microbes could produce health benefits similar to those produced by live probiotics. Occasionally, it might be dangerous to administer live probiotics to people with weak immunity. In such cases, ingestion of paraprobiotics could be a potential alternative. The definition of paraprobiotics refers to the use of inactivated (non-viable) microbial cells or cell fractions to provide health benefits to the consumer. Paraprobiotics have attracted much attention because of their long shelf life, safety, and beneficial effects, such as modulation of immunity, modification of biological responses, reduction of cholesterol, anti-inflammatory, and antiproliferative properties. These features indicate that paraprobiotics may play a vital role in improving the health of the consumer by enhancing particular physiological functions, even though the exact underlying mechanisms have not yet been completely elucidated. In this mini-review, we briefly discuss the historical backgrounds of paraprobiotics and evidence of their health-promoting effects, prophylactic, and therapeutic properties.

• 산경연구논집
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• 제10권9호
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• pp.19-24
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• 2019

Purpose - In the digital era, technology advancement enables goods and services to be produced more efficiently but also create economy risk in the global economy including Indonesia. Previous studies stated that the risk can be mitigated through export diversification. This study investigates strategy to expand the markets for existing products and explore the potential market. Research design, data, and methodology - The criteria was followed using a review and considerations combination through the Focus Group Discussion (FGD) to determine the priority product in trading house of Indonesia. This study implemented market share to explore those products' markets and compare it to other ASEAN countries. Results - The Indonesian potential products are T-shirts, singlets and other vests of textile materials, knitted or crocheted (excluding cotton); food preparations; medicaments consisting of mixed or unmixed products for therapeutic or prophylactic purposes; soap in the form of flakes, granules, powder, paste or in aqueous solution; and cocoa powder, not containing added sugar or other sweetening matter. The market analysis also showed that Indonesia still had not optimally accessed yet the largest market in the world for each product. Conclusions - The government should focus more on increasing the competitiveness of those products, particularly in those global marketplaces.

• Clinical and Experimental Reproductive Medicine
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• 제39권4호
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• pp.182-186
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• 2012

Objective: Many studies have demonstrated that hydrosalpinx has a detrimental effect on the outcome of IVF. Treating hydrosalpinges prior to the IVF procedure in women with hydrosalpinges is thought to improve the likelihood of successful IVF outcome. Vaginal ultrasound-guided aspiration of hydrosalpinx fluid (HSF) with injection of the sclerosing agent in situ might be simpler than invasive procedures like salpingectomy. Therefore, we carried out a retrospective study on the effects of ultrasound-guided HSF aspiration and injection of the sclerosing agent of ultrasonically diagnosed hydrosalpinx on IVF outcome. Methods: In our retrospective study, 97 tubal factor infertile female patients that underwent IVF treatment between January 2005 and December 2012 at the Reproductive Medicine Center of CHA Hospital were divided into two study groups. Fifty-six patients underwent interventional ultrasound sclerotherapy (group 1), and the remaining 41 patients received laparoscopic salpingectomy (group 2) before IVF. We compared the IVF outcomes of the two groups. Results: The results showed that ultrasound-guided HSF aspiration and sclerotherapy have IVF outcomes comparable to laparoscopic salpingectomy. Conclusion: Interventional ultrasound guided sclerotherapy before IVF is an effective and less invasive prophylactic intervention alternative to salpingectomy with hydrosalpinx.

• Asian Pacific Journal of Cancer Prevention
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• 제16권6호
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• pp.2107-2117
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• 2015

Thyroid cancer is the most common endocrine neoplasia. The medullary thyroid carcinoma (MTC) is one of the most aggressive forms of thyroid malignancy,accounting for up to 10% of all types of this disease. The mode of inheritance of MTC is autosomal dominantly and gain of function mutations in the RET proto-oncogene are well known to contribute to its development. MTC occurs as hereditary (25%) and sporadic (75%) forms. Hereditary MTC has syndromic (multiple endocrine neoplasia type 2A, B; MEN2A, MEN2B) and non-syndromic (Familial MTC, FMTC) types. Over the last two decades, elucidation of the genetic basis of tumorigenesis has provided useful screening tools for affected families. Advances in genetic screening of the RET have enabled early detection of hereditary MTCs and prophylactic thyroidectomy for relatives who may not show any symptom sof the disease. In this review we emphasize the main RET mutations in syndromic and non syndromic forms of MTC, and focus on the importance of RET genetic screening for early diagnosis and management of MTC patients, based on American Thyroid Association guidelines and genotype-phenotype correlation.