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The impact of post-warming culture duration on clinical outcomes of vitrified-warmed single blastocyst transfer cycles

  • Hwang, Ji Young;Park, Jae Kyun;Kim, Tae Hyung;Eum, Jin Hee;Song, Haengseok;Kim, Jin Young;Park, Han Moie;Park, Chan Woo;Lee, Woo Sik;Lyu, Sang Woo
    • Clinical and Experimental Reproductive Medicine
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    • v.47 no.4
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    • pp.312-318
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    • 2020
  • Objective: The objective of the study was to compare the effects of long-term and short-term embryo culture to assess whether there is a correlation between culture duration and clinical outcomes. Methods: Embryos were divided into two study groups depending on whether their post-warming culture period was long-term (20-24 hours) or short-term (2-4 hours). Embryo morphology was analyzed with a time-lapse monitoring device to estimate the appropriate timing and parameters for evaluating embryos with high implantation potency in both groups. Propensity score matching was performed to adjust the confounding factors across groups. The grades of embryos and blastocoels, morphokinetic parameters, implantation rate, and ongoing pregnancy rate were compared. Results: No significant differences were observed in the implantation rate or ongoing pregnancy rate between the two groups (long-term culture group vs. short-term culture group: 56.3% vs. 67.9%, p=0.182; 47.3% vs. 53.6%, p=0.513). After warming, there were more expanded and hatching/hatched blastocysts in the long-term culture group than in the short-term culture group, but there was no significant between-group difference in embryo grade. Regarding pregnancy outcomes, the time to complete blastocyst re-expansion after warming is shorter in women who became pregnant than in those who did not in both culture groups (long-term: 2.19±0.63 vs. 4.11±0.81 hours, p=0.003; short-term: 1.17±0.29 vs. 1.94±0.76 hours, p=0.018, respectively). Conclusion: The outcomes of short-term culture and long-term culture were not significantly different in vitrified-warmed blastocyst transfer. Regardless of the post-warming culture time, the degree of blastocyst re-expansion 3-4 hours after warming is an important marker for embryo selection.

Early Outcomes of Robotic Versus Video-Assisted Thoracoscopic Anatomical Resection for Lung Cancer

  • Park, Ji Hyeon;Park, Samina;Kang, Chang Hyun;Na, Bub Se;Bae, So Young;Na, Kwon Joong;Lee, Hyun Joo;Park, In Kyu;Kim, Young Tae
    • Journal of Chest Surgery
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    • v.55 no.1
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    • pp.49-54
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    • 2022
  • Background: We compared the safety and effectiveness of robotic anatomical resection and video-assisted thoracoscopic surgery (VATS). Methods: A retrospective analysis was conducted of the records of 4,283 patients, in whom an attempt was made to perform minimally invasive anatomical resection for lung cancer at Seoul National University Hospital from January 2011 to July 2020. Of these patients, 138 underwent robotic surgery and 4,145 underwent VATS. Perioperative outcomes were compared after propensity score matching including age, sex, height, weight, pulmonary function, smoking status, performance status, comorbidities, type of resection, combined bronchoplasty/angioplasty, tumor size, clinical T/N category, histology, and neoadjuvant treatment. Results: In total, 137 well-balanced pairs were obtained. There were no cases of 30-day mortality in the entire cohort. Conversion to thoracotomy was required more frequently in the VATS group (VATS 6.6% vs. robotic 0.7%, p=0.008). The complete resection rate (VATS 97.8% vs. robotic 98.5%, p=1.000) and postoperative complication rate (VATS 17.5% vs. robotic 19.0%, p=0.874) were not significantly different between the 2 groups. The robotic group showed a slightly shorter hospital stay (VATS 5.8±3.9 days vs. robotic 5.0±3.6 days, p=0.052). N2 nodal upstaging (cN0/pN2) was more common in the robotic group than the VATS group, but without statistical significance (VATS 4% vs. robotic 12%, p=0.077). Conclusion: Robotic anatomical resection in lung cancer showed comparable early outcomes when compared to VATS. In particular, robotic resection presented a lower conversion-to-thoracotomy rate. Furthermore, a robotic approach might improve lymph node harvesting in the N2 station.

Analysis of art & culture consumption propensity according to art & culture experience after COVID19: analysis of differences by art & culture perception (코로나19 이후 문화예술경험에 따른 문화예술 소비성향 분석 - 문화예술 인식에 따른 차이분석 -)

  • So, Eun Hye
    • Korean Association of Arts Management
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    • no.60
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    • pp.155-191
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    • 2021
  • The purpose of this study is to analyze the effect of art and culture experience according to art and culture perception on art and culture consumption. Accordingly, the perception expressed through the experiences of consumers was defined as the delivery of art and culture marketing strategies, and the behavior of consumers enjoying art and culture was measured. The research data were analyzed through an online survey. As a result of the analysis, sense, relation had a significant effect on the hedonistic factor, and the act, sense, emotion and relation had significant effects on the other's consciousness, and the behavioral and emotional factors had a significant effect on the intentional factors. The implication from the experience of relationships with others was found to have a negative(-) effect on all factors, which means to be the result of consumers' anxiety in enjoying art due to the pandemic. It is necessary to develop an online business model for consumers who naturally avoid it, and to narrow the gap between online and offline art and culture. Second, it is thought that sponsorship from companies is necessary so that artists who provide art and culture can produce high-quality contents. In the future, if it was studied the relationship between not only consumers who enjoy art and culture, but also suppliers and artists who provide art and culture, it will be able to understand the culture in-depth.

Differences in Creative Personality and Environment between Higher-Level and Lower-Level Students in Scientific Creativity (창의 성향, 환경, 과정, 산물의 상관 분석 및 과학 창의성 상·하위 학생의 창의 성향과 환경의 차이)

  • Kim, Minju;Lim, Chaeseong
    • Journal of Korean Elementary Science Education
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    • v.41 no.2
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    • pp.395-417
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    • 2022
  • This study aims to analyze the correlation of creative personality, environment, process, and product as related to scientific creativity for different levels of elementary school students. We evaluated 105 fifth graders' responses to two tests: i) the scientific creativity test for creative process and product and ii) the self-report test for creative personality and environment. In the self-report test, creative personality comprises cognitive and affective personality, and creative environment constitutes home and school environments. To attain a deeper understanding of phenomena that cannot be explained by a quantitative analysis, interviews were conducted with four students who had the highest scores in creative product and four students who had the lowest scores in creative product while having higher-than-average scores in creative process. First, correlation of creative personality and environment were not significant. Second, in the interviews, students who had the highest scores in scientific creativity had common characteristics, namely, the ability to endure current difficulties to achieve future success and the propensity to listen to other people's ideas critically. Third, students who had the highest scores in creativity hailed from families that respected their opinions, whereas students with the lowest scores belonged to families that disregarded or neglected their opinions. Finally, this study specifies the criteria that should be considered for affective and environmental aspects of scientific creativity education.

The Effect of Content Layout in Mobile Shopping Product Page on Product Attitude and Purchase Intention: Focusing on Consumer Cognitive Responses Depending on Regulatory Focus (모바일 쇼핑몰 상세페이지 콘텐츠 레이아웃 형태가 제품태도 및 구매의도에 미치는 영향: 조절초점에 따른 소비자 인지 반응 중심으로)

  • Park, Kyunghee;Seo, Bonggoon;Park, Dohyung
    • Knowledge Management Research
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    • v.23 no.2
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    • pp.193-210
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    • 2022
  • The rapid development of mobile technology and the improvement of network speed are providing convenience to various services, and mobile shopping malls are no exception. Although efforts are being made to promote sales by combining various technologies such as customized recommendations using big data and specialized personalization services based on artificial intelligence, most mobile shopping malls have the same detailed page information structure including detailed product information. In this context, in this study, it was determined that the content layout of the product detail page and the mobile product detail page layout tailored to the consumer's preference should be presented according to the consumer's preference. Based on Higgins' Regulatory Focus Theory, a study of consumer propensity revealed that the content layout arrangement on a product detail page, when presented in an F-shape, informs the consumer that it is organized. If presented in a Z-shape, vivid information was recognized, and it was examined whether the product attitude and purchase intention were affected. As a result, when the content layout composition was presented as a layout arrangement in the form of a sense of unity and organization, prevention-focused consumers were positively affected by product attitudes and purchase intentions, and promotion-oriented consumers felt freedom. When presented in an arrangement, it was confirmed that the product attitude and purchase intention were affected.

An Improvement Study on the Hydrological Quantitative Precipitation Forecast (HQPF) for Rainfall Impact Forecasting (호우 영향예보를 위한 수문학적 정량강우예측(HQPF) 개선 연구)

  • Yoon Hu Shin;Sung Min Kim;Yong Keun Jee;Young-Mi Lee;Byung-Sik Kim
    • Journal of Korean Society of Disaster and Security
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    • v.15 no.4
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    • pp.87-98
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    • 2022
  • In recent years, frequent localized heavy rainfalls, which have a lot of rainfall in a short period of time, have been increasingly causing flooding damages. To prevent damage caused by localized heavy rainfalls, Hydrological Quantitative Precipitation Forecast (HQPF) was developed using the Local ENsemble prediction System (LENS) provided by the Korea Meteorological Administration (KMA) and Machine Learning and Probability Matching (PM) techniques using Digital forecast data. HQPF is produced as information on the impact of heavy rainfall to prepare for flooding damage caused by localized heavy rainfalls, but there is a tendency to overestimate the low rainfall intensity. In this study, we improved HQPF by expanding the period of machine learning data, analyzing ensemble techniques, and changing the process of Probability Matching (PM) techniques to improve predictive accuracy and over-predictive propensity of HQPF. In order to evaluate the predictive performance of the improved HQPF, we performed the predictive performance verification on heavy rainfall cases caused by the Changma front from August 27, 2021 to September 3, 2021. We found that the improved HQPF showed a significantly improved prediction accuracy for rainfall below 10 mm, as well as the over-prediction tendency, such as predicting the likelihood of occurrence and rainfall area similar to observation.

A Study on the Effect among the Service Quality of Coffee Shop, Store Attitude and Store Loyalty: Focusing on the Construal Level (커피전문점 서비스품질, 점포태도, 점포충성도의 영향관계 연구 : 개인 해석수준의 영향을 중심으로)

  • Kang, Hwa-Seok
    • The Korean Journal of Franchise Management
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    • v.9 no.2
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    • pp.39-52
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    • 2018
  • Purpose - This study investigates the effect of service quality of coffee shop on store attitude and store loyalty. It demonstrates that the individual's behavior identification level plays a moderating role when the service quality of coffee shop affects store attitude. Conceptually drawing on Brady & Cronin's three-dimensional model of service quality, this study examines the effect of service quality of coffee specialty store on customer's attitudes and loyalty. Also, according to construal level theory, it examines the individual's propensity difference whether the individual's behavior identification level on service quality and store attitude has a moderating effect Research design, data, and methodology - This study used Brady & Cronin's three-dimensional service quality model, and 183 valid cases collected through the questionnaire survey were used for data analyses. For hypothesis testing, regression analysis, multiple regression analysis, and covariance analysis were conducted. Result- As a result of this study, first, it is confirmed that service quality has a positive effect on store attitude toward coffee shop. Second, the difference of an individual's construal level did not have a moderating effect on the influential relationship of service quality on the store attitude of coffee shop. This is because the influence of the service quality is greater than the difference between groups at the construal level. Therefore, there was no moderating influence according to construal level. Third, the store attitude of coffee specialty store has a positive effect on store loyalty. Conclusions - It is confirmed that there is a difference in the effect of service quality and store attitude on general and college students. This suggests that it can be used to establish marketing strategies by segment. And, the college students were found to be more influenced by physical environment quality factor among three dimensions of service quality. Therefore, it is necessary to further improve efforts to raise the level of service quality perception through physical environmental factors such as clean and pleasant environment including the interior of a coffee shop, and internal table arrangement. The empirical study on the moderating effects of customer's tendency of difference is meaningful in the absence of empirical studies.

Comparison of Laparoscopic and Open Gastrectomy for Patients With Gastric Cancer Treated With Neoadjuvant Chemotherapy: A Multicenter Retrospective Study Based on the Korean Gastric Cancer Association Nationwide Survey

  • Seul Ki Oh;Chang Seok Ko;Seong-A Jeong;Jeong Hwan Yook;Moon-Won Yoo;Beom Su Kim;In-Seob Lee;Chung Sik Gong;Sa-Hong Min;Na Young Kim;the Information Committee of the Korean Gastric Cancer Association
    • Journal of Gastric Cancer
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    • v.23 no.3
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    • pp.499-508
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    • 2023
  • Purpose: Despite scientific evidence regarding laparoscopic gastrectomy (LG) for advanced gastric cancer treatment, its application in patients receiving neoadjuvant chemotherapy remains uncertain. Materials and Methods: We used the 2019 Korean Gastric Cancer Association nationwide survey database to extract data from 489 patients with primary gastric cancer who received neoadjuvant chemotherapy. After propensity score matching analysis, we compared the surgical outcomes of 97 patients who underwent LG and 97 patients who underwent open gastrectomy (OG). We investigated the risk factors for postoperative complications using multivariate analysis. Results: The operative time was significantly shorter in the OG group. Patients in the LG group had significantly less blood loss than those in the OG group. Hospital stay and overall postoperative complications were similar between the two groups. The incidence of Clavien-Dindo grade ≥3 complications in the LG group was comparable with that in the OG group (1.03% vs. 4.12%, P=0.215). No statistically significant difference was observed in the number of harvested lymph nodes between the two groups (38.60 vs. 35.79, P=0.182). Multivariate analysis identified body mass index (odds ratio [OR], 1.824; 95% confidence interval [CI], 1.029-3.234; P=0.040) and extent of resection (OR, 3.154; 95% CI, 1.084-9.174; P=0.035) as independent risk factors for overall postoperative complications. Conclusions: Using a large nationwide multicenter survey database, we demonstrated that LG and OG had comparable short-term outcomes in patients with gastric cancer who received neoadjuvant chemotherapy.

Validity of the Happiness-Enhancing Activities and Positive Practices Inventory(HAPPI) Scale in Physical Activities Participation in Korean Old Adults (신체활동참여 한국 노인을 위한 행복증진활동(HAPPI)척도의 구인타당도)

  • Kim, Woo-Kyung
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.7
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    • pp.285-294
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    • 2019
  • The purpose of this study is to assess construct validity and verify the concept of the Happiness-enhancing Activities and Positive Practices Inventory(HAPPI) developed by Henricksen & Stephens(2013), for Korean old adults who participating physical activities with measuring happiness-related propensity. In this study, the research model was confirmed by evidenced based on the content validity, EFA, construct validity of the latent structure analysis with CFA, reliability as internal consistency. Using self-reported questionnaire conducted among 370 participants who physical activities. Total of 344 data were selected. As a result, internal consistency α was acceptable. Evidence-based on convergent and discriminant of the CFA as GFI=.925, CFI .962, TLI .953, and RMSEA .062 appeared significantly. Model goodness-of-fit, C.R. ratio(Critical ratio: estimates/SE) and Squared Multiple Correlations(SMC), and average variance extracted(AVE) was verified with the hypothesis of the model. Therefore, HAPPI validity evidence for the model fit was confirmed. In conclusion, the HAPPI 4 factors and 16 items(Other-focused, Personal recreation and interests, Achievement, Self-Concordant Work, Spiritual and thought-related) has reliable evidence to apply for Korean old adults and applicable assessment of happiness.

The Effect of Regulatory Focus on the Link Between Purchase Behavior and Redemption Behavior

  • Kim, Ji Yoon
    • Asia Marketing Journal
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    • v.15 no.4
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    • pp.51-60
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    • 2014
  • Previous research on loyalty program has verified the factors that influence redemption behavior and the understanding of the mechanism of redemption behavior with academic and practical implications. However, these research has not proven boundary conditions in which the phenomena can be strengthened or weakened- that is, the moderating effect remains unclear. The inclusion of moderating variables can provide a more extensive understanding of the mechanism of this behavior from academic and managerial perspectives alike. Therefore, this current research proposes regulatory focus as a moderating variable, which has received scarce attention in the study of loyalty program behavior, especially individual characteristic variables that, in turn, affect the consumers' purchasing behavior in various ways. Previous research on consumer decision making investigates the differential role of regulatory focus as a series of stages. Regulatory focus theory posits that people depend on the two types of regulatory focus when pursuing goals: promotion focus vs. prevention focus. The former induces tendencies to recognize a goal as a hope and ideal, as something that satisfies the need for accomplishment, and to be sensitive to the presence of a positive outcome of the match and to match the pursuit of goals. On the other hand, the latter tends to regard a goal as the responsibility or obligation to achieve the goal, has a tendency to avoid failure to meet a target, and is sensitive to the presence of the negative consequences that do not reach the target. The following propositions are suggested: 1) The effect of higher accumulation effort level on delaying point redemption speed will be relatively more pronounced for customers with prevention focus. 2) The effect of higher accumulation effort level on large redemption unit size will be relatively more pronounced for customers with prevention focus. 3) The effect of higher accumulation effort level on hedonic redemption ratio will be relatively more pronounced for customers with promotion focus. Therefore, this research provides a moderating variable that has the potential to be used as a reference for market segmentation and affects the relationship between point accumulation effort and three sides of point redemption behavior. On this basis, the direction for the future research on this issue is recommended. Future research could verify these propositions conducting a survey of customers' propensity of regulatory focus in conjunction with the history of the loyalty program of data. This would provide a more realistic effect on the usage behavior of loyalty program consumers by providing useful implications for both marketing practitioners and researchers.

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